Guest guest Posted December 29, 2004 Report Share Posted December 29, 2004 Hmmm. . . I was always under the impression that sucralose was not absorbed. I was corrected and they DO claim it is absorbed. Jan From http://www.splenda.com/page.jhtml?id=splenda/hcp/safety.inc Over a 20-year period after the discovery of sucralose in 1976, more than 100 studies were conducted to support the safety of sucralose. These studies, the results of which are summarized below, were designed to determine how sucralose is absorbed, metabolized, and excreted by the body and to assess its potential effects on the body. These studies have shown that sucralose is safe for use. The safety of sucralose has also been confirmed by years of both domestic and international use. Absorption, Distribution, Metabolism, and Elimination of Sucralose Absorption: Most ingested sucralose passes through the digestive system unchanged and without causing gastrointestinal side effects. Studies have shown that about 15% of ingested sucralose is passively absorbed from the gastrointestinal tract. Distribution: The small amount of sucralose that is absorbed is distributed to essentially all tissues. Studies show that there is no active transport of sucralose across the blood-brain barrier, across the placental barrier, or from the mammary gland into milk. Metabolism: Although derived from sucrose, sucralose is not perceived by the body as a carbohydrate. Unlike carbohydrates, sucralose is not broken down during its passage through the body. In humans, approximately 2% of the amount consumed is biotransformed into toxicologically insignificant components that are rapidly excreted in urine. Elimination: Most ingested sucralose is excreted unchanged in feces, without gastrointestinal effects. Of the small amount that is absorbed, most is eliminated unchanged in urine within about 24 hours. Jan Patenaude, RD Director, Medical Nutrition Signet Diagnostic Corp. www.nowleap.com 1- (toll free) Fax: DineRight4@... or JanP@... Disease Management Programs for Irritable Bowel Syndrome and Migraine caused by Food Sensitivity IMPORTANT - This e-mail message is intended only for the use of the individual or entity to which it is addressed, and may contain information that is privileged, confidential and exempt from disclosure under applicable law. If you have received this message in error, you are hereby notified that we do not consent to any reading, dissemination, distribution or copying of this e-mail message. If you have received this communication in error, please notify the sender immediately by e-mail and telephone ( toll free) and destroy the transmitted information. E-mail transmission cannot be guaranteed to be secure or error-free as information could be intercepted, corrupted, lost, destroyed, arrive late, incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message, which arise as a result of e-mail transmission. Quote Link to comment Share on other sites More sharing options...
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