Guest guest Posted May 16, 2006 Report Posted May 16, 2006 DHEA has a short half life under an hour. When DHEA is sulfated in the liver to become DHEA-S the half life is as long as 24 hours. Chris > > I was wondering if you know of any reasons that supplementing DHEA > cream would cause it to build up in the blood instead of converting > down? > > Joy > Quote
Guest guest Posted May 16, 2006 Report Posted May 16, 2006 Hi I was wondering because my DHEA is always way below range, so I was put on 25mg cream every morning. After 8 weeks my labs showed my DHEA level was at 2400 (range 100-300) and I felt horrible. My Dr. took me off of it immediately, and couldn't understand why it went so high (she was pretty shocked). My sex hormones were still really low (except Progesterone which I supplement) so obviously it wasn't converting. If I understand what you are saying correctly, the supplement wouldnt have built up due to its short life. Do you know of any other reasons my levels would have gone so high with supplementation? My last labs (one month after discontinuing DHEA) showed my DHEA even lower than usual. I need to get it up, but am afraid to supplement again due to the horrid symptoms I had last time. Any ideas? Joy > > DHEA has a short half life under an hour. When DHEA is sulfated in > the liver to become DHEA-S the half life is as long as 24 hours. > > Chris > > > > > > > I was wondering if you know of any reasons that supplementing DHEA > > cream would cause it to build up in the blood instead of converting > > down? > > > > Joy > > > Quote
Guest guest Posted May 16, 2006 Report Posted May 16, 2006 Your high DHEA was likely driving down your cortisol and that is probably why you felt bad. What I was trying to show that the cream being converted in your liver (absorbtion through skin ends up in liver) will be turned into DHEA-S. Most drugs are made with the liver in mind, being that the end effect of the drug is what it turns into in the liver. Your cream was converted to DHEA-S and that is why your level was so high. Supposedly, taking Dhea will not suppress natural Dhea, but I'm suspect. When it comes to low sex hormones I don't recommend relying on DHEA to fix, but to treat those hormones directly. In the future if you want to treat your low DHEA just for its sake, try the pill form. I recommend a brand called Nature something. It's in a purple bottle. Start with a quarter pill (6 1/4 mg) and work up as tests show (every 6 weeks) is needed. Chris > > > > > > I was wondering if you know of any reasons that supplementing DHEA > > > cream would cause it to build up in the blood instead of converting > > > down? > > > > > > Joy > > > > > > Quote
Guest guest Posted May 16, 2006 Report Posted May 16, 2006 " I recommend a brand called Nature something. " I forgot to say it's in a purple bottle and Walgreens has it. Chris > > > > > > > > I was wondering if you know of any reasons that supplementing DHEA > > > > cream would cause it to build up in the blood instead of converting > > > > down? > > > > > > > > Joy > > > > > > > > > > Quote
Guest guest Posted May 16, 2006 Report Posted May 16, 2006 So, that sounds like one should take the cream every two days? The cream sound like an easier deal, no? wrote: DHEA has a short half life under an hour. When DHEA is sulfated inthe liver to become DHEA-S the half life is as long as 24 hours. Chris>> I was wondering if you know of any reasons that supplementing DHEA > cream would cause it to build up in the blood instead of converting > down?> > Joy> New Yahoo! Messenger with Voice. Call regular phones from your PC and save big. Quote
Guest guest Posted May 16, 2006 Report Posted May 16, 2006 The cream may be more potent than equivlent dose in pill form. If cream comes in a syringe then you could try lowering the dose, but I doubt that taking it every other day would be enough. Chris > > > > I was wondering if you know of any reasons that supplementing DHEA > > cream would cause it to build up in the blood instead of converting > > down? > > > > Joy > > > > > > > > > Quote
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