Kennedy's disease

[Guest guest]

I could find no reference to Kennedy's disease in the archives or on the

website. Is there any information about it for LDN? It is caused by "

trinucleotide repeat expansion " , " the expanded CAG repeats underlying KD

create an abnormal structure within the androgen receptor called expanded

polyglutamine " (http://www.mdausa.org/publications/Quest/q93kd.cfm_

" A treatment that's developed for any one of the nine polyglutamine

diseases is likely to be effective against the others, " Fischbeck says, and,

in an ironic, but encouraging twist, drugs that work against KD might also

work against ALS. "

So, is the opposite likely to be true? A drug (LDN) helpful for ALS might

also be helpful for KD?

Kennard