Guest guest Posted February 19, 2006 Report Posted February 19, 2006 Luke,If I thought these drugs would quickly and safely reverse lipoatrophy, I would have started them ages ago when speculation first began that they might be of use.There are good reasons why these agents MIGHT help, but studies so far have not been miraculous, though some improvements have been noted. Some improvements have been noted by measurements and x-rays, but there has not been dramatic improvement in terms of what patients see, which is really what is important.I'm continuing to keep my ears open, and maybe reliable benefit will be found sometime. I'm more optimistic about piogitazone than rosiglitazone, but not enough to pop more pills. Despite what some think on this list may think, I'm a most enthusiastic supporter of taking the lowest number of drugs possible.In the back of my mind, there is the spectre of Rezulin®, a related drug that killed a few folks. Wait and see........On Feb 19, 2006, at 8:23 AM, PozHealth wrote:I read yesterday that both rosiglitazine and pioglitazone both increase limb fat. Having skinny legs from zerit. I started it on April 1997 and took it for 2 1/2 yrs till dec 99.... 6 yrs later and no fat has returned,, SO which of the drugs would you suggest as least side effects and dosage.. and most effective etc.. currently on truvada and .sustiva and vl<50 and cd4 500's.. thanks... I tried leg workouts but the skinniness remains the same esp w/ lots of veins showing from the knee to the ankle... this is where it looks the thinnest any ideas.. thank you,, luke Barrowpozbod@... Quote
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