Re: Overheating?

[Guest guest]

Here's some ideas:

I hope you are using Viramune in combination with other anti-virals as resistance to Viramune develops very quickly when used as a single agent;

Allergic reactions to Viramune are relatively common, although less common than with Ziagen. If a drug was causing me to lose my hair and run a fever upon mild exertion, I would be extremely cautious about using it, especially if I had alternative drugs to use. My partner started losing his eyebrows at one point - and when he stopped using Crixivan they quickly grew back in. So everyone reacts differently, but if you don't like the reactions from a drug, why continue. I can understand you like the results, but I wouldn't find this sort of side-effect acceptable;

While a temperature of 98.1 - 99.1 (36,7 to 37,3) is quite normal, a temperature of 100.0 -101.3 (37,8-38,5) on mild exertion is clearly not - unless you are extremely obese. If this elevated temperature is due to a rapid reconstitution of your immune system due to increased levels of Interleukin-2 production, then Indomethacin (known in the US as Indocin-SR) will normalize your temperature. If your elevated temperature is due to a drug reaction to Viramune, then Indomethacin will have little or no effect on the fever;

I am curious what changes you have seen in your total White Count. Your increase in Lymphocytes from 1,150 to 1,900 is a good change, but a large increase in other types of White Cells is possibly indicative of an allergic reaction to the drug;

Reyataz (atazanavir) is the only protease inhibitor which does not disrupt the lipid metabolism in most people, so if you have no other alternatives to Viramune, this is one.

>> In March 2006 I changed to Viramune (nevirpine) from Kaletra.> The big change in labs was that my absolute lymfocyte count went from> 1,15*10^9 to 1,9*10^9, my cd4% from 38 to 45%, thus CD4's from 440 to 770.> (Plus cholesterol and triglyc. went back to normal and liver enzymes a bit> up).> > Since then I am dealing with two issues:> a) Alopecia> Overheating> > a) I lost all my leg hair, arm hair, my eye lashed became blond, as my> eyebrows, and my head hair has patches.> When in rest, my bodytemp is normal (36,7 to 37,3). But, when I walk -> and it's summer - or do stuff like clean the house or shop, my body temp> goes up to 37,8-38,5 degrees celcius.> > I had my thyroid checked but those labs are fine (tsh 2,0 and t4 13,2).> > Any insight in what is happening? The doctors have no clue whatsoever.> The only thing I can come up with is hypothalamus-trouble, and that would> not be great.> > Thanks so much,> >

[Guest guest]

It's very diffucult to figure out what this might be.   It doesn't sound like any kind of allergy, nor are these effects typically seen with Virimune.  If the fevers persist, or you should develop other problems, especially a rash or oral ulcers, bring it to the attention of your doctor immediately.Norm is correct that Crixivan is often associated with skin/hair/nail problems, but this too is not allergic.  Crixivan seems to block the maturation of keratin, causing all manner of skin problems in some people. "In March 2006 I changed to Viramune (nevirpine) from Kaletra.The big change in labs was that my absolute lymfocyte count went from1,15*10^9 to 1,9*10^9, my cd4% from 38 to 45%, thus CD4's from 440 to 770.(Plus cholesterol and triglyc. went back to normal and liver enzymes a bitup).Since then I am dealing with two issues:a) Alopeciab) Overheatinga) I lost all my leg hair, arm hair, my eye lashed became blond, as myeyebrows, and my head hair has patches. When in rest, my bodytemp is normal (36,7 to 37,3). But, when I walk -and it's summer - or do stuff like clean the house or shop, my body tempgoes up to 37,8-38,5 degrees celcius.I had my thyroid checked but those labs are fine (tsh 2,0 and t4 13,2)." Barrowpozbod@...