lymphocytes

[Guest guest]

,

Ranges will vary every day, especially if there is a bug in the system.

Over what period of time are the labs? However, 49% down to 10% is a pretty

big drop. Could it be a lab error, maybe a mathematical error? When the

lymphocytes are added to the other parts of the WBC--monocytes, eosinophils,

basophils, neutrophils--do they total 100%? I just stumbled across this web

page. http://www.fpnotebook.com/HEM91.htm When you click on " Lymphocyte

Count " , Number II gives a loose " normal " reference range for WBC, CBC, and

much more. The " normal " ranges will vary by performing lab or hospital,

patient's age, and other factors.

Antipov

mother to , 4 years old, X-SCID, 2 BMTS @ Duke, normal T cell

function, SCIG weekly

[Guest guest]

- why was she having the lab test done? It would mean that at the

time of the test she had what they call a " left shift " and a bacterial

infection was on board.

Ursula - mom to Macey (10,CVID) and (13)

http://members.cox.net/maceyh

Immune Deficiency Foundation http://www.primaryimmune.org

Pediatric PID email list

Modell Foundation http://jmfworld.org

[Guest guest]

It would mean that at the

> time of the test she had what they call a " left shift " and a

bacterial

> infection was on board.

>

>Thanks! That would make sense. She was just having follow up lab

work done so they ran a CBC but she went on antibiotics again for an

ear infection.

Ana 13mo IgG etc ???

[Guest guest]

A left shift is when the neutrophil count is " left shifted " -- i.e.

when the immature neutrophils, the bands are increased --- in the CBC diff

there are two types of neuts they count-the bands and the segs to get the

ANC (absolute neutrophil count) you add the two together and multiply w/

the total WBC-

The " left shift " got its name because way back when they wrote out the CBC

diff, the bands were the first thing they wrote on the left side of the

paper-and they wrote from left to right across the paper with the counts.

When the bands were increased, they called it a left shift.. The name has

just stayed with it all these years.

When my boys have CBCs done (they get them a lot b/c of their neutropenia)

and there is a n increase in band neutrophils, then we assume it is

bacterial. This is one way they decide if they need to start IV

antibiotics with fever (if they have a left shift) I'll try to locate a

file on my computer or you can go to www.shwachmandiamondamerica.org

<http://www.shwachmandiamondamerica.org/> and click on " community " then on

the Blood forum. I have info about left shift there.

My boys also have a left shift in their bone marrow---- which indicates

something different than a left shift in the peripheral blood. As for

their lymphocytes- their counts jump around a lot. It isn't unusual for

them to be lymphopenic.

Here is info on left and right shifts:

In a differential count, the presence of many band cells and their pecusors

is known as a shift to the left and indicates bacterial infection. A shift

to the right describes the presence of mature, hypersegmented neutrophils

that have more nuclear segments than normal; his commonly occurs with

pernicious anemia and hepatic disease. Increased band cells and low total

WBC count reflect bone marrow depression (as in typhoid fever), known as a

degenerative shift. A regenerative shift implies stimulation of the bone

marrow (as in pneumonia and appendicitis) and may be noted by increased band

cells, metamyelocytes and myelocytes together with a high WBC count. " from

my nursing implications of Diagnostic tests, procedures

~Pattie~

" It is easy to take liberty for granted when you have never had it taken

from you. " ~ Dick Cheney

_____

From: [mailto: ] On Behalf Of

Ursula Holleman

Sent: Thursday, March 02, 2006 8:16 PM

Subject: Re: lymphocytes

- why was she having the lab test done? It would mean that at the

time of the test she had what they call a " left shift " and a bacterial

infection was on board.

Ursula - mom to Macey (10,CVID) and (13)

http://members.cox.net/maceyh

I was looking at Ana's lab reports and her lymphocytes have dropped

from 49% to 10%. I'll ask the doc in three weeks when I see them what

that means, but any clues in the mean time?

mom of Ana, 13mo with IgG/???? def.

_____

[Guest guest]

Hi Elinor,

No, a major part of your immune system is the lymph system, not the

nervous system. See this short article http://www.healthline.com/sw/wl-

how-your-lymph-system-works

Gretchen