Rich this might interest you if you are doing mitochondria

[Guest guest]

It takes into account the binding of adenylates to Mg2+ and the

importance of the free and Mg-bound states for the translocase and

adenylate kinase equilibria (in healthy plants). I hadnt seen that

level of detail before in my light studies on this subject, tho maybe

you have.

http://jxb.oxfordjournals.org/cgi/reprint/57/10/2133.pdf

I'm interested in col 2 of page 2135, where they revise the concept of

adenylate energy charge -- by, again, distinguishing free and Mg-bound

states. Energy charge (the adenylate mol fraction of ATP + half the

adenylate mole fraction of ADP) is an index of energization that's

canonically supposed to regulate lots of path-committment enzymes. This

could be an important part of my bacteria's behaviour if they face

energy restriction due to, say, NO inhibition of O2 respiration.

1247543 claims that energy charge very sensitively regulates

translation initiation (in a eucaryote) but I only have the abstract.

There's also an AMP-dependent kinase, in eucaryotes only, which goes

around phosphoylating things when [AMP] rises.

[Guest guest]

Hi, .

Thanks. I'll take a look at it when I can.

Rich

>

> It takes into account the binding of adenylates to Mg2+ and the

> importance of the free and Mg-bound states for the translocase and

> adenylate kinase equilibria (in healthy plants). I hadnt seen that

> level of detail before in my light studies on this subject, tho

maybe

> you have.

>

> http://jxb.oxfordjournals.org/cgi/reprint/57/10/2133.pdf

>

> I'm interested in col 2 of page 2135, where they revise the

concept of

> adenylate energy charge -- by, again, distinguishing free and Mg-

bound

> states. Energy charge (the adenylate mol fraction of ATP + half

the

> adenylate mole fraction of ADP) is an index of energization that's

> canonically supposed to regulate lots of path-committment enzymes.

This

> could be an important part of my bacteria's behaviour if they face

> energy restriction due to, say, NO inhibition of O2 respiration.

> 1247543 claims that energy charge very sensitively regulates

> translation initiation (in a eucaryote) but I only have the

abstract.

> There's also an AMP-dependent kinase, in eucaryotes only, which

goes

> around phosphoylating things when [AMP] rises.

>