Re: Med Hypotheses:Spirochetal cyst forms in neurodegenerative disorders

[Guest guest]

> :

> Do you know anything about AB Macdonald from this pathology lab?

> And what " endowments " is (s)he talking about- having image data

> removed? Hmmmm what's up?

> Barb

I believe Dr Mac has posted on eurolyme. At any rate, a couple

decades ago, he fluoroimaged borreliae in a few abortive fetuses -

possibly also in some other situations of transplacental passage, I

forget.

I think(?) he just means that spriochetal cyst images have not

successfully competed for space in new texts or editions. This would

accord with the more general eclipse of the idea of bacterial

pleomorphism. At least some " pleomorphic variants " isolated (and

preserved) by old workers have turned out (according to stronger

genomic age technology) to actually be separate strains or species -

rather than being merely different phenotypes of the same genotype.

I vaguely understand that this has been a major factor in tarnishing

pleomorphism theory generally. As competition for lab spots has

increased over the decades, it would make sense that the possibility

of " recovering " your standing in the competition for your own lab,

after having once been associated with a " tainted " topic, has

decreased. Therefore it can sometimes be hard for a tainted idea to

make a comeback even if there are some arguments in its favor.

As for the question of whether the spirochetal cyst could be

illegitimate or artifactual, I have no doubt whatsoever that it is

genuine.

Cell-wall-deficient bacteria are one sort of pleomorphism that is

fully accepted as real, but I think the occurance or at least the

pathogenicity of CWD in vivo are generally held in doubt by the

larger community.