Re: J & W: : virginiamycin/gut bugs in horses

[Guest guest]

/:

I know the species in horses aren't all the same as the species in

humans- but I just find it interesting, that in horses syndrome X

is like type 2 diabetes and has overlap symptoms of CFS in humans-

exercise intolerance, fatigue, hypothyroidism, weight gain (and

insulin resistance.)

Their digestive systmes are not like ours- but I find it extremely

interesting that it's fermentation and over growth of a few species

killing off other species that set up the mechanism that's a systemic

domino effect.

It's assumed that insulin resistance (I/R) is the root cause - But

COULD it be gut bug imbalance that comes first?

I'm no expert on this- but am starting to read about it.

Horses are controlled by a strick low carb, low sugar diet which

means NO grass - (and horses are grazing aimals)

But that's treating symptoms- it's not a cure.

Vets are getting mighty close to calling it an autoimmune...

I feel like there's something to be learned here if we can drag it

out of the observations and data from horses.

QUOTE

This overgrowth, particularly of streptococci and lactobacilli, was

associated with lactic acid accumulation and the death of gram-

negative bacteria leading to endotoxin release, both of which were

postulated to be the cause of this condition. END QUOTE

and it's Streptococcus bovis that's the bacteria that virginiamycin

kills but the paper acknowledges:

QUOTE:

Virginiamycin, a streptogramin antibiotic, has been used to prevent

starch overload-induced laminitis, by preventing the overgrowth of

gram-positive bacteria which ferment carbohydrate and produce lactic

acid (40). It is not known whether it is the inhibition of lactate

production per se and/or inhibition of the formation and absorption

of other bacterial products which mediates this protective effect.

END QUOTE

Identification of Equine Cecal Bacteria Producing Amines in an In

Vitro Model of Carbohydrate Overload

S. R. ,1* M.-L. Baillon,2 A. N. Rycroft,3 P. A. ,2 and J.

Elliott1

Departments of Veterinary Basic Sciences,1 Pathology and Infectious

Diseases, Royal Veterinary College, London,3 The Waltham Centre for

Pet Nutrition, Melton Mowbray, Leicestershire, United Kingdom2

FULL PAPER : http://aem.asm.org/cgi/reprint/69/4/2087

Received 2 October 2002/ Accepted 7 January 2003

BACKGROUND INFO:

read the section on Virginamycin..

Antimicrobial Growth Promoters Used in Animal Feed: Effects of Less

Well Known Antibiotics on Gram-Positive Bacteria

http://www.pubmedcentral.gov/articlerender.fcgi?artid=153145

I have soome reading to do.

Barb

> > >

> > > Interesting that. One thing that jumped out at me was the

> > accumulation of

> > > fat in the intestine,Inappropriate gut flora promoting the

> laying

> > down of

> > > fat ..Now, many with a yeast infection report a paunch..I

wonder

> > > ......anyone else notice an accumulation of fat?..

> > > Here's the direct link

> > >

> > > http://www.pubmedcentral.gov/articlerender.fcgi?

> > tool=pubmed & pubmedid=1646732

> > > 2

> > >

> > >

> > >

> > > [infections] newish Raoult paper on

> > immunology of

> > > whipples disease

> > >

> > >

> > > Free text. Wanna read it, gotta go

> > >

> > > http://www.pubmedcentral.gov/articlerender.fcgi?

> > > tool=pubmed & pubmedid=16467322

> > >

> > >

> > >

> > >

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