Guest guest Posted December 4, 1998 Report Share Posted December 4, 1998 > Technically the bill is still in committee so it appears it will be dead for > this particular legislative session. But, it will be reintroduced in the 1999 > legislative session. > > Hugs, Liz > > Dear Liz: Thanks for the info! Keep after them, or they'll forget about us!! Is there anything the rest of us can do to help? Lovette Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 8, 1999 Report Share Posted June 8, 1999 << " still wondering though if animals can carry HepC? " ... what about the meat we eat?? ine. >> From all that I've read, only Hep A, never C, can be tranmitted through any type of food. The instances I've heard about came from contaminated foods (fecal matter) in the food products...normally meat, shell fish, etc. If anyone knows differently I'd be interested in hearing about it, but I really doubt there's transmission in that manner. - Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 1999 Report Share Posted September 22, 1999 > Date: Tue, 21 Sep 1999 17:59:13 -0600 > From: " Hoggan Clan " <banock@...> >Subject: There has to be an answer SOMEWHERE! Dear Debi, >It is our understanding that " achondroplasia does not have neuro problems usually, >while some other forms of dwarfism do. Curtis is achon and he has *many* neurological problems due to spinal cord injury from a severe stenosis of his foramen magnum. The stenosis was so severe before it was decompressed, that it permanently damaged his brain stem and upper spinal cord. Curtis used to have central sleep apnea because of his neurological problems. We are praying for Mandy and the Hoggan Clan. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 1999 Report Share Posted October 20, 1999 Hi Does anyone here have recipes for kids bath paints? ELLEN Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 20, 2000 Report Share Posted January 20, 2000 In a message dated 01/19/2000 6:15:57 AM Central Standard Time, onelist writes: << Or you can make it a heck of a lot easier on yourself and just megadose on Vitamin C for a few days. >> That's oK if you don't have an viral or bacterial infections working... but if you do have any infections, the Olive Leaf, echinacea, goldenseal and GSE have anti-viral and anti-bacterial properties in them that will combat these microbes that Vit. C alone cannot do. Blessings, Jan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 20, 2000 Report Share Posted January 20, 2000 In a message dated 01/19/2000 6:15:57 AM Central Standard Time, onelist writes: << ps - I used the stick blender & it traced in about a minute! I LOVE that thing! >> Can you tell me what a " stick blender " is and how you use it? I'm a newbie when it comes to soap making, in fact, I haven't made the first batch yet!! Got my stuff ordered tho, and we should begin in the next week or so. Thanks Blessings, jan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 20, 2000 Report Share Posted January 20, 2000 I have had questions in my own mind about what I can sell and what I cannot because it's someone else's recipe. If I get a recipe out of a book and there are no copywrite laws, then I assume it's OK to use and sell the soaps, lotions etc made from these recipes. If I go to another's web site and they have recipes posted, can you use these recipes if it's not stated otherwise? Please clarify the rules for me, as I am new to this whole thing. I want to sell my products, but I don't want to " steal " recipes from others. Thank you. Blessings, Jan << the former and/or present member of this list, and member of the soap & > toiletries web ring, who has stolen and posted, as her own work, the > copyrighted file that I generously allowed to post in the toiletries > library can expect an invoice. >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2000 Report Share Posted April 5, 2000 I am not sure if I am responding the right way here. I have been reading and learning alot here but wanted to comment to Virginia and also about leaving the shots out. I ddi the same thing. I talked to my pharmicist and fount out that the med is still stable at temps up to 95 for 7 days. Virginia, I had the same problem with my husband. He and I had had problems for many years and i just kept trying to work it out. Finding out about my having hep c actually opened my eyes as to what i was doing. I was living my life for him and not myself. Being sick i put my foot down saying i had to concentrate on getting better. We are now separated after 4 months on the combo. He does feel like he took me for granted for too long but he has felt bad before and i dont trust him anymore. The only thing is that my 12 year old dau has real problems dealing with my illness and she moved out of state with my husband. I am hoping she comes around, but decided it would be worse to force her to stay. Our three sons are still here in the same city as me and 2 have been so supportive of me. I love them dearly. One lives with me and i am so glad ...was maried 21 years and never lived on my own before and going thru side effects and then just had a recheck and have not cleared the virus after 4 months. going to continue for 2 months and re check then. I have had all the side effects but i had some before the combo treatment. I have cirrhosis already. I have lost 30 pounds as have no appetite. I have to force myself to eat for energy and to not get upset stomach. I hate complaining about the sides so people around me dont really realize how i am feeling until i have to give in and go home sick from work. Sorry if i went on and on bout myself but feel that even if no one reads or hears , it is still good for me to get things down in writing.I do want to know if anyone has had any problems with sinuses bleeding easily when blow nose or even a couple of times i found one ear bleeding a little. Not sure if i just scratched it or not but I dont think i did. Anyway, Virginia, the best i can say is be honest and upfront with him but look out for urself while trying to get better.... Stress causes worse sides i have found. Dawn --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2000 Report Share Posted April 5, 2000 Dawn, I am so glad you wrote. You have explained everything in a nutshell. I don't trust my husband like I use too. I get so tired of being told I am a hypochondriac and my illness isn't as bad as I make it out to be. I am living with the illness and not him. I am going to start focusing on myself more. My little ones need their Mom. I too have nosebleeds alot. I can't blow my nose without it bleeding. I have also lost weight because of poor appetite and fatigue. I force myself to eat also to avoid tube feedings again. It is so hard to eat at times. I know if I don't I will only get more tired and then not be able to eat . It is a vicious cycle. I appreciate all of you who have responded. I am going to take care of myself for me and my children. If my husband could care less, it is his problem. I have to be around for my children. They need me even if he says he doesn't need me. I will survive this thing with or without him. I never thought I would be saying all of this. I think I will plan a trip with my children and parents to Laredo, TX. and take a break from things. I need a vacation. I haven't had one in a good long time. I think one is due. Hugs to all for your help, Virginia Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2000 Report Share Posted April 6, 2000 Dawn, Please try and eat if only a little all the time. My husband has Hep C and has developed hyperglycemic diabetes (and no one even suspected that's why he lost 30 pounds). He didn't need to lose the weight either. He is having a heart cath today, the final test before being placed on the transplant list. We are separated by 1000 miles, not by choice and it is very difficult for both of us to cope with this disease. I cannot stress enough to EAT EAT EAT. It is very difficult to start trying to gain weight when you develop other problems like managing blood sugar etc and you need to be in your best physical condition if you should need a transplant. God Bless, MJ Re: Digest Number 95 I am not sure if I am responding the right way here. I have been reading and learning alot here but wanted to comment to Virginia and also about leaving the shots out. I ddi the same thing. I talked to my pharmicist and fount out that the med is still stable at temps up to 95 for 7 days. Virginia, I had the same problem with my husband. He and I had had problems for many years and i just kept trying to work it out. Finding out about my having hep c actually opened my eyes as to what i was doing. I was living my life for him and not myself. Being sick i put my foot down saying i had to concentrate on getting better. We are now separated after 4 months on the combo. He does feel like he took me for granted for too long but he has felt bad before and i dont trust him anymore. The only thing is that my 12 year old dau has real problems dealing with my illness and she moved out of state with my husband. I am hoping she comes around, but decided it would be worse to force her to stay. Our three sons are still here in the same city as me and 2 have been so supportive of me. I love them dearly. One lives with me and i am so glad ...was maried 21 years and never lived on my own before and going thru side effects and then just had a recheck and have not cleared the virus after 4 months. going to continue for 2 months and re check then. I have had all the side effects but i had some before the combo treatment. I have cirrhosis already. I have lost 30 pounds as have no appetite. I have to force myself to eat for energy and to not get upset stomach. I hate complaining about the sides so people around me dont really realize how i am feeling until i have to give in and go home sick from work. Sorry if i went on and on bout myself but feel that even if no one reads or hears , it is still good for me to get things down in writing.I do want to know if anyone has had any problems with sinuses bleeding easily when blow nose or even a couple of times i found one ear bleeding a little. Not sure if i just scratched it or not but I dont think i did. Anyway, Virginia, the best i can say is be honest and upfront with him but look out for urself while trying to get better.... Stress causes worse sides i have found. Dawn --------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2000 Report Share Posted April 6, 2000 We are both moving to Texas the first of June. Thanks for the thoughts. MJ Re: Digest Number 95 > > > > I am not sure if I am responding the right way here. > I have been reading and > learning alot here but wanted to comment to Virginia > and also about leaving > the shots out. I ddi the same thing. I talked to my > pharmicist and fount out > that the med is still stable at temps up to 95 for 7 > days. > > Virginia, > > I had the same problem with my husband. He and I had > had problems for many > years and i just kept trying to work it out. Finding > out about my having hep > c actually opened my eyes as to what i was doing. I > was living my life for > him and not myself. Being sick i put my foot down > saying i had to > concentrate on getting better. We are now separated > after 4 months on the > combo. He does feel like he took me for granted for > too long but he has felt > bad before and i dont trust him anymore. The only > thing is that my 12 year > old dau has real problems dealing with my illness > and she moved out of state > with my husband. I am hoping she comes around, but > decided it would be worse > to force her to stay. Our three sons are still here > in the same city as me > and 2 have been so supportive of me. I love them > dearly. One lives with me > and i am so glad ...was maried 21 years and never > lived on my own before and > going thru side effects and then just had a recheck > and have not cleared the > virus after 4 months. going to continue for 2 months > and re check then. I > have had all the side effects but i had some before > the combo treatment. I > have cirrhosis already. I have lost 30 pounds as > have no appetite. I have to > force myself to eat for energy and to not get upset > stomach. I hate > complaining about the sides so people around me dont > really realize how i am > feeling until i have to give in and go home sick > from work. Sorry if i went > on and on bout myself but feel that even if no one > reads or hears , it is > still good for me to get things down in writing.I do > want to know if anyone > has had any problems with sinuses bleeding easily > when blow nose or even a > couple of times i found one ear bleeding a little. > Not sure if i just > scratched it or not but I dont think i did. Anyway, > Virginia, the best i can > say is be honest and upfront with him but look out > for urself while trying > to get better.... Stress causes worse sides i have > found. > > Dawn > > > > --------------------------------- > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2000 Report Share Posted April 6, 2000 We are both moving to Texas the first of June. Thanks for the thoughts. MJ Re: Digest Number 95 > > > > I am not sure if I am responding the right way here. > I have been reading and > learning alot here but wanted to comment to Virginia > and also about leaving > the shots out. I ddi the same thing. I talked to my > pharmicist and fount out > that the med is still stable at temps up to 95 for 7 > days. > > Virginia, > > I had the same problem with my husband. He and I had > had problems for many > years and i just kept trying to work it out. Finding > out about my having hep > c actually opened my eyes as to what i was doing. I > was living my life for > him and not myself. Being sick i put my foot down > saying i had to > concentrate on getting better. We are now separated > after 4 months on the > combo. He does feel like he took me for granted for > too long but he has felt > bad before and i dont trust him anymore. The only > thing is that my 12 year > old dau has real problems dealing with my illness > and she moved out of state > with my husband. I am hoping she comes around, but > decided it would be worse > to force her to stay. Our three sons are still here > in the same city as me > and 2 have been so supportive of me. I love them > dearly. One lives with me > and i am so glad ...was maried 21 years and never > lived on my own before and > going thru side effects and then just had a recheck > and have not cleared the > virus after 4 months. going to continue for 2 months > and re check then. I > have had all the side effects but i had some before > the combo treatment. I > have cirrhosis already. I have lost 30 pounds as > have no appetite. I have to > force myself to eat for energy and to not get upset > stomach. I hate > complaining about the sides so people around me dont > really realize how i am > feeling until i have to give in and go home sick > from work. Sorry if i went > on and on bout myself but feel that even if no one > reads or hears , it is > still good for me to get things down in writing.I do > want to know if anyone > has had any problems with sinuses bleeding easily > when blow nose or even a > couple of times i found one ear bleeding a little. > Not sure if i just > scratched it or not but I dont think i did. Anyway, > Virginia, the best i can > say is be honest and upfront with him but look out > for urself while trying > to get better.... Stress causes worse sides i have > found. > > Dawn > > > > --------------------------------- > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2000 Report Share Posted April 6, 2000 MJ wish there was some way we could get you 2 together. Being together helps.....Connie --- " M. J. Ruble " <mjruble@...> wrote: > Dawn, > > Please try and eat if only a little all the time. > My husband has Hep C and > has developed hyperglycemic diabetes (and no one > even suspected that's why > he lost 30 pounds). He didn't need to lose the > weight either. He is having > a heart cath today, the final test before being > placed on the transplant > list. We are separated by 1000 miles, not by choice > and it is very > difficult for both of us to cope with this disease. > I cannot stress enough > to EAT EAT EAT. It is very difficult to start > trying to gain weight when > you develop other problems like managing blood sugar > etc and you need to be > in your best physical condition if you should need a > transplant. God Bless, > MJ > > Re: Digest Number 95 > > > > I am not sure if I am responding the right way here. > I have been reading and > learning alot here but wanted to comment to Virginia > and also about leaving > the shots out. I ddi the same thing. I talked to my > pharmicist and fount out > that the med is still stable at temps up to 95 for 7 > days. > > Virginia, > > I had the same problem with my husband. He and I had > had problems for many > years and i just kept trying to work it out. Finding > out about my having hep > c actually opened my eyes as to what i was doing. I > was living my life for > him and not myself. Being sick i put my foot down > saying i had to > concentrate on getting better. We are now separated > after 4 months on the > combo. He does feel like he took me for granted for > too long but he has felt > bad before and i dont trust him anymore. The only > thing is that my 12 year > old dau has real problems dealing with my illness > and she moved out of state > with my husband. I am hoping she comes around, but > decided it would be worse > to force her to stay. Our three sons are still here > in the same city as me > and 2 have been so supportive of me. I love them > dearly. One lives with me > and i am so glad ...was maried 21 years and never > lived on my own before and > going thru side effects and then just had a recheck > and have not cleared the > virus after 4 months. going to continue for 2 months > and re check then. I > have had all the side effects but i had some before > the combo treatment. I > have cirrhosis already. I have lost 30 pounds as > have no appetite. I have to > force myself to eat for energy and to not get upset > stomach. I hate > complaining about the sides so people around me dont > really realize how i am > feeling until i have to give in and go home sick > from work. Sorry if i went > on and on bout myself but feel that even if no one > reads or hears , it is > still good for me to get things down in writing.I do > want to know if anyone > has had any problems with sinuses bleeding easily > when blow nose or even a > couple of times i found one ear bleeding a little. > Not sure if i just > scratched it or not but I dont think i did. Anyway, > Virginia, the best i can > say is be honest and upfront with him but look out > for urself while trying > to get better.... Stress causes worse sides i have > found. > > Dawn > > > > --------------------------------- > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2000 Report Share Posted April 6, 2000 MJ wish there was some way we could get you 2 together. Being together helps.....Connie --- " M. J. Ruble " <mjruble@...> wrote: > Dawn, > > Please try and eat if only a little all the time. > My husband has Hep C and > has developed hyperglycemic diabetes (and no one > even suspected that's why > he lost 30 pounds). He didn't need to lose the > weight either. He is having > a heart cath today, the final test before being > placed on the transplant > list. We are separated by 1000 miles, not by choice > and it is very > difficult for both of us to cope with this disease. > I cannot stress enough > to EAT EAT EAT. It is very difficult to start > trying to gain weight when > you develop other problems like managing blood sugar > etc and you need to be > in your best physical condition if you should need a > transplant. God Bless, > MJ > > Re: Digest Number 95 > > > > I am not sure if I am responding the right way here. > I have been reading and > learning alot here but wanted to comment to Virginia > and also about leaving > the shots out. I ddi the same thing. I talked to my > pharmicist and fount out > that the med is still stable at temps up to 95 for 7 > days. > > Virginia, > > I had the same problem with my husband. He and I had > had problems for many > years and i just kept trying to work it out. Finding > out about my having hep > c actually opened my eyes as to what i was doing. I > was living my life for > him and not myself. Being sick i put my foot down > saying i had to > concentrate on getting better. We are now separated > after 4 months on the > combo. He does feel like he took me for granted for > too long but he has felt > bad before and i dont trust him anymore. The only > thing is that my 12 year > old dau has real problems dealing with my illness > and she moved out of state > with my husband. I am hoping she comes around, but > decided it would be worse > to force her to stay. Our three sons are still here > in the same city as me > and 2 have been so supportive of me. I love them > dearly. One lives with me > and i am so glad ...was maried 21 years and never > lived on my own before and > going thru side effects and then just had a recheck > and have not cleared the > virus after 4 months. going to continue for 2 months > and re check then. I > have had all the side effects but i had some before > the combo treatment. I > have cirrhosis already. I have lost 30 pounds as > have no appetite. I have to > force myself to eat for energy and to not get upset > stomach. I hate > complaining about the sides so people around me dont > really realize how i am > feeling until i have to give in and go home sick > from work. Sorry if i went > on and on bout myself but feel that even if no one > reads or hears , it is > still good for me to get things down in writing.I do > want to know if anyone > has had any problems with sinuses bleeding easily > when blow nose or even a > couple of times i found one ear bleeding a little. > Not sure if i just > scratched it or not but I dont think i did. Anyway, > Virginia, the best i can > say is be honest and upfront with him but look out > for urself while trying > to get better.... Stress causes worse sides i have > found. > > Dawn > > > > --------------------------------- > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2000 Report Share Posted April 7, 2000 woo hoo texas!! where? I'm near Dallas. Good support groups in Texas alley/ ICQ 12631861 alleypat@... http://www.flash.net/~alleypat Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2000 Report Share Posted April 22, 2000 (((((((((((((((((( Dawn )))))))))))))))))))) big hugs to you! I know I have learned to let go a lot of things, esp housework. Hubby just doesn't see what steps on and I'm usually too tired to worry about it. I've found that if I ask him he will do what I ask. He's good about that. I try not to nag, but " select my battles " so to speak. I try to ask him to do the things that really need done and not wear him out on the petty stuff. Like we can let the dishes stack, but we aren't leaving glasses and plates all over the house ya know. He can do what he wants in his office, but the living room must remain picked up (not always dusted and not always vacuumed but at least his underwear is somewhere else haha). The floor might only get mopped once a month, but the toilets have to be clean. Energy is a precious commodity for a hepper! alley/ ICQ 12631861 alleypat@... http://www.flash.net/~alleypat Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2000 Report Share Posted April 22, 2000 (((((((((((((((((( Dawn )))))))))))))))))))) big hugs to you! I know I have learned to let go a lot of things, esp housework. Hubby just doesn't see what steps on and I'm usually too tired to worry about it. I've found that if I ask him he will do what I ask. He's good about that. I try not to nag, but " select my battles " so to speak. I try to ask him to do the things that really need done and not wear him out on the petty stuff. Like we can let the dishes stack, but we aren't leaving glasses and plates all over the house ya know. He can do what he wants in his office, but the living room must remain picked up (not always dusted and not always vacuumed but at least his underwear is somewhere else haha). The floor might only get mopped once a month, but the toilets have to be clean. Energy is a precious commodity for a hepper! alley/ ICQ 12631861 alleypat@... http://www.flash.net/~alleypat Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2000 Report Share Posted April 22, 2000 Virginia............. how are you doing hon? alley/ ICQ 12631861 alleypat@... http://www.flash.net/~alleypat Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2001 Report Share Posted September 8, 2001 Here's mine . . . let me know if it works! Always, SJ, hooking up the scanner Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2001 Report Share Posted September 8, 2001 SJ I'm not able to get anything . You will need to try again. Don't know what's up. Get in touch. I'm on I'm just acting like DZ when he's workin.........I'm a sneakin!!!!!!!!!!!!! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2003 Report Share Posted May 14, 2003 Hi all: Well it is two weeks and two days since my double knee replacements. The doctors are amazed at my progress. I can bend my left knee to 97 and my right to 105. I can get in and out of a car with absolutely no problem whatsoever and up and down stairs. My gait with the walker is almost the same as it was before the surgery. Things are going too good to be true. My therapist doesn't understand this either. I think it is due to a positive attitude and the fact that I'm sick of being handicapped with bad knees. I've been pushing myself. I got to see my new knees yesterday and they are beautiful. Carole - AKA Thorn Willowweb, AKA Daisy Proudfoot of Standelf. God grant me the Senility to forget the people I never liked anyway, the good fortune to run into the ones I do, and the eyesight to tell the difference. ·.,¸¸,.·´¯`·.,¸¸,.·´¯`·.»§«©©©»§«·.,¸¸,.·´¯`·.,¸¸,.·´¯`· I think I lost my mind, so watch where you step! ·.,¸¸,.·´¯`·.,¸¸,.·´¯`·.»§«©©©»§«·.,¸¸,.·´¯`·.,¸¸,.·´¯`· Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2003 Report Share Posted May 15, 2003 Hi Carole I am following your progress and you are doing sooooooo well.....congratulations! Sally Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 4, 2005 Report Share Posted May 4, 2005 Re:Message: 9 - Thanks for the references and Matts original post. I think I'll email this to Wheldon, who has kindly responded to other questions in the past, and see what he says. As a medical microbiologist and MD treating actual cases (in Cpn) he may have a more complex take on this. If he replies I'll post it. I'll also ask his opinion on the " metro wall " phenomenon-- herx or sensitization, that is the question. Wheldon, in my read, is referring to what Stratton calls the " cryptic " form (Stratton actually referrs to two cryptic stages, one of which is especially sensitive to nicotinamide related agents- it took me a third read of his patent papers to register this) as the non-replicating phase. A good puzzle to follow! Jim Date: Tue, 03 May 2005 21:31:44 -0000 From: " Hodologica " <usenethod@...> Subject: Jim - metronidazole Jim, Here are the papers: http://www.ub.rug.nl/eldoc/dis/medicine/e.j.van.der.wouden/c8.pdf http://tinyurl.com/62tz2 And if those dont work, here is Matts earlier post #92, from which I got both papers: infections/messag e/92 Your idea about the metro-wall could be right, but I cant really say. I dont know if the reduced (active) form circulates - I kinda suspect not - in the 2nd paper there they found that non-metro- reducing cells were unharmed when mixed with metro and metro- reducing cells. The reduced form may be so reactive that it exists only something very roughly like one second or less, before being re- oxidized in a reaction that damages some other molecule. Also, enzymes are not depleted or worn out by use; they are just molecular machines that basically stay in good shape, re-usably. Saturation occurs if there is too much substrate present, relative to the number of copies of the enzyme - the enzymes get " backed up " , at which point the enzymatic reaction does not stop, but its rate has maxed out and substrate may continue to accumulate. But some enzymes in the liver (and elsewhere?) are inducible, meaning the body can sense their saturation and respond by synthesizing extra enzyme copies. All my knowledge is pretty vague since I'm just taking early college bio classes now. I think I see what you mean about what Wheldon's saying. By non- replicating form, do you know if he means the elementary body, or something else? - Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 4, 2005 Report Share Posted May 4, 2005 I found this posted on another list I belong to and thought it might be of interest to those who have played out the abx approaches and want a more rigorous alternative. Probably mega-expensive with all the supplements! Jim THE USE OF PHARMAX NUTRICEUTICALS IN THE TREATMENT OF CHRONIC LYME DISEASE by Dietrich Klinghardt PhD/MD A Few Words on Chronic Lyme Disease Chronic Lyme disease is a fast-spreading problem in the USA and worldwide. Classical Lyme disease is caused by a bacterial spirochete called Borrelia burgdorferi. Conventional belief attributes Lyme Disease conveyance through tick bites. Interestingly to the physician, more recent literature has shown that also certain stinging flies, spiders and even some mosquitoes can infect humans with this spirochete. This means that the disease vector can be more widespread than previously anticipated. Lyme disease typically does not occur alone but together with a number of co-infections. Classical Lyme disease, also known as Borrelia, affects the immune system in predictable ways: it lowers the white blood count and lessens the host¡¦s immunity. When the immune system becomes dysfunctional, the patients then become infected with a multitude of secondary bacterial, fungal, mycoplasmal and viral infections. A necessary co-condition for the thriving of infectious organisms in the system is the presence of toxic metals and other environmental toxins. Chronic Lyme disease affects the immune system by rendering it blind to the existence of Borrelia and other co-infections, including parasites. Lyme can also affect the musculo-skeletal system with recurrent joint problems and fibromyalgia type pain. A third presentation affects the central nervous system with a multitude of related symptoms including emotional changes, psychiatric problems and neurological problems, i.e. numbness, paralysis and strange abnormal sensations. The area most commonly affected is the brain and the face including the teeth, jawbone, ears and sinuses. The symptoms are caused by the presence of neurotoxins that are created by the organisms. Neurotoxins are usually peptides and other substances intended to alter the host¡¦s immune system and make the host a comfortable environment for the proliferation of Borrelia and the co-infections. It is our experience that most Lyme patients, by the time the infection has become chronic, have multiple parasites in their bowel. Co-infections from the herpes virus family, sackie¡¦s viruses, influenza viruses, echo viruses and the measles virus seem to be common. Frequently they also have one of several mycoplasma species present and a multitude of other bacterial infections. Fungi always thrive in a Lyme-infected patient. The treatment therefore needs to be broad based and address all these co- infections in order to succeed. Treatment for Lyme disease is often unsuccessful when it targets only the Lyme spirochete but not the existing co-infections. 1) Borrelia affects the immune system by lessening the host¡¦s immunity. 2) The host becomes a comfortable environment for co-infections. 3) Treatment needs to be broad based, addressing co-infections. A Few Words on the GI Tract It is imperative to understand that the reservoir for many of these co-infections is the gastrointestinal (GI) tract. It typically contains eight to twelve pounds of living organisms. Many of these in the chronic Lyme patient are parasites and abnormal bacteria, fungi, viruses and mycoplasmas, which set up housekeeping in the gut and spread from there periodically to the other tissues. In terms of sheer numbers, the GI tract is home to 100,000 billion microorganisms at any one point in time. Considering that the average person has approximately 10,000 billion mammalian cells in their body, one could say there are 10 times more of ¡¥them¡¦ than of ¡¥us¡¦. The monolayer of epithelial cells of the intestinal mucosa constitutes the largest surface in the body that is exposed to the environment. In other words, one cell layer separates you from the outside world in your GI tract! It is estimated that this mucosal surface is equal to the size of two tennis courts. The gut can turn into a storehouse of infectious organisms and must be understood in order to be treated successfully. A Few Words on Pharmax Nutriceuticals I have chosen the nutriceuticals from Pharmax LLC for dealing with many of the issues outlined in this article. Secondly, they manufacture their own nutriceuticals with strict quality controls, as reflected in their ISO 9001 certification. Most companies merely repackage products manufactured elsewhere. As a prime manufacturer, Pharmax produce their own base materials and their unique freeze-drying technology enables the company to use a solvent-free manufacturing process. Thirdly, I find the products are pure and intelligently designed. Specific Treatment for Co-infections in the GI Tract 1) Freeze Dried Garlic (700mg freeze dried garlic concentrate [Allium sativum] per capsule) The active antimicrobial in garlic is allicin (Ankri & Mirelman, 1999). It has MIC (minimum inhibitory concentration) values very similar to antibiotics and antifungals for their prospective targeted organism. For example, the MIC for Staphylococcus aureus is 26, Escherichia coli is 44 and Candida albicans is 36 (these are all astoundingly low numbers, indicating that allicin is a potent antibiotic or antifungal for these organisms!). Allicin also kills protozoa¡¦s such as Cryptosporidium, E. histolytica (Mirelman et al., 1987) and Giardia ( et al., 2000). Allicin is effective against viruses such as the Rotavirus (Blake, 1983), Influenza virus (Fenwick & Hanley, 1985) and viruses from the herpes family (i.e. HHV-6 and others), to name just a few (Tsai et al., 1985). Yet it is not cytotoxic and does not harm the beneficial bacteria in the gut, i.e. the lactic acid bacteria such as Lactobacillus acidophilus and Bifidobacterium bifidum (Rees et al., 1993). In treatment, I advise 2 capsules after each meal - a total of between 4 and 6 capsules each day. 2) AlliCinn (500mg freeze dried garlic concentrate [Allium sativum], 200mg freeze dried cinnamon bark oil concentrate [Cinnamomum cassia] per capsule) I generally give 2 capsules, three times a day after a meal. 3) Antimicrobial Complex (200mg barberry bark standardized extract [berberis vulgaris], 50mg goldenseal standardized extract [Hydrastis canadensis], 100mg freeze dried garlic concentrate [Allium sativum], 50mg freeze dried wormwood oil concentrate [Artemesia absinthium] per capsule) We also include the Antimicrobial Complex to treat other often- undefined bacterial co-infections. Artemesia absinthium has been shown to be an ideal agent to treat Babesia, which is one of the organisms frequently present as a co-infection with Lyme disease (it is an intracellular parasite similar to malaria). Berberis vulgaris is a potent antibacterial agent (Ruggeri et al., 1991). I generally advise one capsule, three times a day with meals. 4) Intestinal Purifier (3g psyllium husk, 1.75g FOS, 1g L- glutamine, 2g resistant starches, 2g freeze dried prune puree and 0.25g quercetin per 10g scoop) 5) HLC High Potency (4 billion Lactobacillus acidophilus and Bifidobacterium bifidum per capsule) To replace the normal bowel flora, we always recommend Pharmax¡¦s human lactic commensals, i.e. HLC High Potency for bowel restoration. I recommend 1 - 2 capsules after each meal. 6) Intestinal Complex (150mg slippery elm bark extract 4:1 [ulmus fulva], 100mg marshmallow root extract 4:1 [Althaea officinalis], 85mg camomile flower standardized extract [Matricaria recutita], 100mg marigold flower extract 4:1 [Calendula officinalis], 50mg licorice root standardized extract [Glycyrrhiza glabra], 50mg gamma-oryzanol per capsule). 7) Permeability Complex I (1,500mg FOS, 1,000mg L-glutamine, 500mg aspartic acid, 500mg L-arginine, 20mg magnesium, 330mg vitamin C, 100mg N-acetyl glucosamine [NAG], 100mg quercetin, 15mg zinc, 20mg essential oil of ginger [Zingiber officinale], 5,000iu vitamin A, 100iu vitamin E) Provides luminal nutrients for a healthy GI mucosa (Souba, 1990). I advise 1 ¡V2 scoops (5 ¡V 10 grams), three times a day with meals Specific Treatment for Borrelia, Ehrlichiosis, Babesia and Mycoplasma Infections 1) Freeze Dried Garlic (700mg freeze dried garlic concentrate [Allium sativum] per capsule) For the specific treatment of Borrelia, we use Freeze Dried Garlic in the dose already recommended. The garlic will first eliminate the microorganisms and parasites in the bowel before the allicin and its breakdown products can be active in the connective tissue and later also in the brain. Allicin, the primary active ingredient, has been shown to cross the blood-brain barrier and it is a surprisingly effective antimicrobial agent against the Lyme spirochete even in the brain and the CNS. However, high doses are recommended, usually upwards from 5,600mg total daily intake given in divided doses every 6 hours. This translates to 4 capsules QID. The way I often titrate the individual dose is by body odor. When a patient gets a slight garlic body odor, the desired dosage is reached. 2) Pyloricin (700mg total capsule fill of freeze dried oregano oil concentrate [Thymus capitus], freeze dried clove oil concentrate [syzygium aromaticum], freeze dried ginger oil concentrate [Zingiber officinale] and freeze dried wormwood oil concentrate [Artemesia absinthium]) Babesia, Ehrlichiosis and Borrelia are often sensitive to the product Pyloricin. The most effective ingredient here is again oil of artemesia for its tremendous effect on Babesia. The second most important ingredient is the oregano oil, which we found to be most effective against Borrelia, Babesia, Ehrlichiosis and Mycoplasmas. Clove oil and ginger have a synergistic effect. I usually give one capsule TID taken on an empty stomach along with the rest of the program. (Again, if the patient experiences cramping as a result of the treatment, a drop or two of peppermint oil in a little bit of water taken at the same time will alleviate the symptoms. Peppermint also potentiates the effect of all the other essential oils.) Specific Treatment for Yeast Infections 1) Freeze Dried Garlic (700mg freeze dried garlic concentrate [Allium sativum] per capsule) 2) Colon Guard (350mg freeze dried garlic concentrate[Allium sativum], 60mg freeze-dried cinnamon bark oil concentrate[Cinnamomum cassia], 150mg magnesium caprylate, 215mg calcium caprylate per capsule) 3) Caprylate Complex (500mg magnesium caprylate and calcium caprylate per capsule) 1. Freeze Dried Garlic or AlliCinn: 2 capsules three times daily with meals. 2. Antimicrobial Complex: One capsule three times daily with meals. 3. Pyloricin: One capsule twice daily with meals. 4. HLC High Potency: One capsule twice daily with meals. 5. Intestinal Complex: One capsule three times daily with meals. 6. Intestinal Purifier: One 10g scoop taken once daily with a meal. 7. Colon Guard: 2 capsules three times daily with meals. 8. Caprylate Complex: One capsule three times daily with meals. 9. Permeability 1 One to 2 scoops twice daily with meals 9. Detoxification Heavy metals and environmental toxins change the inner environment of the patient. This milieu is a necessary sine qua non for the presence of harmful microorganisms and the inability of the immune system to deal with them. Therefore, every patient with chronic Lyme Disease has to be detoxified. We have developed new simple steps in the elimination of toxic metals from the body. We are using a product that contains a large amount of branched chained amino acids and is most effective in detoxifying heavy metals from the central nervous system. Also, glutathione is critically important and must be added. Detoxification Treatment - One Year Duration. 1) BMI Balance (100ƒÝg chromium, 23.75g whey protein concentrate, 1.5g conjugated linolenic acid, 225mg L-carnitine, 1.2g FOS per 30g scoop) It is made from whey protein, which contains these important amino acids in ideal amounts. I get patients to take 30g per meal. 2) Glutathione Precursors (300mg N-acetyl cysteine, 200mg glutamic acid, 200mg alpha-lipoic acid per capsule) Mineral Replacement Treatment Metals are bound to various structures in the connective tissue, the cell walls and the surfaces of intracellular organelles. They are in the cell on binding sites that are usually reserved for other beneficial minerals. Only when the body is depleted of minerals do heavy metals permanently attach to those sites. In order to displace the heavy metals from those binding sites, the system has to be saturated with beneficial minerals. 1) Trace Mineral Complex (20mg iron, 10mg manganese, 200ƒÝg chromium, 200ƒÝg selenium, 200ƒÝg iodine, 1mg copper, 25mg zinc, 200ƒÝg molybdenum, 100ƒÝg vanadium, 2mg boron, 450mg vitamin C, 25ƒÝg nickel, 35ƒÝg of silica per capsule - all listed in elemental amounts). I recommend one capsule with each meal for 6 to 12 months. 2) Selenium CWS (100ƒÝg elemental selenium per drop) 3) Mag:Cal Citrate (75mg calcium, 75mg magnesium, 100ƒÝg boron, 15mg of vitamin B6 per capsule - the minerals are listed in elemental amounts.) 1. BMI Balance: One scoop (30grams) per meal replacement, with water or milk for one year. 2. Glutathione Precursors: One capsule per day, taken with food for one year. 3. Trace Mineral Complex: One capsule with each meal for 6 to 12 months. 4. Selenium CWS: 12 drops per day dropped over food, for 6 months. 5. Trace Mineral CWS: 5 to 10 drops with each capsule dose of the Trace Mineral Complex. 6. Mag:Cal Citrate: 2 to 4 capsules with the evening meal. Treating Neurological Symptoms When the patient¡¦s presentation is primarily neurological, we have to pay attention to the fatty acids. Fatty acids make up 80% of the weight of the brain, and are necessary to maintain healthy barriers within the brain. The cell walls are made up to a large degree of lipids that can only be intact if a patient has a good input of lipids on a daily basis. Fish oil and fish oil derivatives are the most important component to be observed in the treatment of Lyme Disease. My current most popular way of dosing this is to use DriCelle EFA 950. 1) DriCelle EFA 950 (300mg DHA, 400mg EPA, 100mg GLA, 150mg ALA per teaspoon) It is best to test the different oil products with ART or EAV, or through Ared-cell Membrane Fatty Acid Test. The current ¡§Body Bio Fatty Acid Test¡¨ is also good. The test, however, overlooks the fact that we like patients to have extremely high levels of EPA and DHA in the abnormal range, which is protective against viral replication and neurological damage from Lyme disease. Whenever the patient takes oils that are meant to be absorbed into the blood and to then travel from there into the brain, the oil absorption should be enhanced by giving an enzyme with a high amount of lipase. We therefore recommend that the patient take the product called: 2) Pure Pancreatin (700mg vegetable pancreatin per capsule) 1. DriCelle EFA 950 One half teaspoon, four times a day in water or juice with a meal. 2. Pure Pancreatin One to 2 capsules every time DriCelle EFA 950 is taken. For severe neurological symptoms such as paralysis, check for the presence of a co-infection called Bartonella henselae (also called cat scratch disease). This illness responds to high doses of antibiotics, which should be the preferred treatment of choice. We have been treating Lyme Disease with the above protocols plus the addition of bee venom therapy two to three times a week for a prolonged period of time, and have often seen good and lasting results with this approach. For the treatment of Babesiosis, we have sometimes to include the antibiotic Mepron for 3 to 6 weeks. Treating Immune System Symptoms If the immune system symptoms predominate, I like to include: 1) Ginseng Combination (350mg Siberian ginseng root, 350mg Korean panax ginseng root per capsule) This has a multitude of beneficial effects on the immune system. I give 2 capsules BID with meals. 2) Immusol (2ml Echinacea angustafolia, 2ml Echinacea purpurea, 2ml Elderberry liquid extract, 0.3ml CLA, 300mg Vitamin C, 10mg Zinc) A combination of immune stimulating factors, which is also excellent (Coeugniet & Elek, 1987; Craig, 1999). I give 3 teaspoons daily with food. 1. Ginseng Combination Two capsules BID with meals 2. Immusol Three teaspoons daily with food. Neurotoxin Binding Neurotoxins are constantly excreted by the body through the liver into the bile ducts and from there into the small intestines. Neurotoxins have a high affinity for nervous system tissue. The small intestines are lined with nerve endings. On the way through the small intestine, most neurotoxins are re-absorbed by the nerve endings and travel from there to the spinal cord and back up into the brain. They are on an endless rotation through these different systems without leaving the body. It has been shown that several substances can intercept the neurotoxins on their way down and bind them in the stool so they are excreted. 1) Beta Sitosterol (100mg b-sitosterol per capsule) 2) Liver Support and Detoxification (200mg choline bitartrate, 100mg milk thistle seed standardized extract [silybum marianum], 25mg inositol, 25mg L-methionine, 80mg turmeric standardized extract [Curcuma longae], 50mg licorice root standardized extract [Glycyrrhiza glabra], 50mg calcium glucarate, 25mg indole-3- carbinol, 50ƒÝg biotin, 25mg limonene, 25mg L-glycine per capsule) 1. Beta Sitosterol One to 2 capsules four times a day between meals 2. Liver Support and Detoxification Two capsules per day with a meal. Laboratory Diagnosis Lyme Disease is a chronic disease that is responsible for a multitude of illnesses including chronic low back pain, migraine headache, fibromyalgia, chronic fatigue and even some cancers. It is most often misdiagnosed as another illness. For the diagnosis, we are currently recommending the lymphocyte transformation test that is not available in the USA. Here, the most successful diagnostic procedure is the direct proof of the microbial presence through phase contrast dark field microscopy after using species- specific fluorescent stain (Bowen Research laboratory). Other tests used: Western Blot Test, PCR Test and Lymphocyte Transformation Test. Optimal Diet and The Four Pillars of Nutrient Supplementation from Pharmax. Multivitamins and minerals, fatty acids, antioxidants and probiotics form the Four Pillars of the Pharmax approach, and these, along with an optimal diet form the necessary underlying base upon which sound treatment is built. However, as long as a significant amount of parasites and microorganisms are present in the gut, these also are fed with the multivitamins approach. Therefore we usually suggest an initial three-week approach of using the anti-infectious agents and bowel restoration products only to reduce the amount of pathogenic flora in the gut before starting on the multivitamins, antioxidants and other rich nutrient sources. After the initial three weeks of antimicrobial use, the following Four Pillars can be brought into play: Summary of the Four Pillars of Supplementation (see Pharmax flier) 1. Vitamins and Minerals: Multivitamin & Mineral (adult formula) Two capsules per day with food or Multi Omega Plex Two scoops per day with food. Vitamin C Powder One gram per day with food. Natural E 300 One capsule per day with food 2. Fatty Acids DHA/EPA 1000 Five grams per day with food or EFA 950 Five grams per day with food or Omega 3:6:9 Ad lib with food 3. Antioxidants Endogenous Antioxidants One capsule per day with food or Glutathione Precursors One capsule per day with food plus Carotenoid Complex Two capsules per week with food plus Phyto Antioxidants Two capsules per week with food 4. Probiotics & Prebiotics: HLC High Potency Two capsules per day with food The Use of Antibiotics in Treating Lyme Disease The recommended medical treatment for Lyme disease and the associated co-infections is the use of antibiotics. The typical treatment of mycoplasma infections takes several six-week cycles of high doses of antibiotics. We currently believe that the approach using natural antibiotics and antimicrobials has superior long-term effects. However sometimes the patient cannot respond to a particular approach and another approach has to be chosen. We occasionally have to include the use of intravenous antibiotics. Other ¡¥Alternative¡¦ treatments include the use of microcurrent, ozone therapy, ultraviolet blood irradation, hyperbaric oxygen, bee venom therapy, ozone sauna, acupuncture and colon hydrotherapy. We recommend the following web sites for further information: 1. www.Lymenet.com (antibiotic schedules) 2. www.chronicneurotoxins.com (neurotoxin binding agents) 3. www.neurotherapy.com (bee-venom therapy) 4. www.pharmaxllc.com (nutriceuticals) References Antimicrob Agents Chemother 30 (3): 499-501. Ankri, S. & Mirelman, D. (1999) Antimicrobial properties of allicin from garlic. Microbes and Infection. 2, 125-129 Beck M.A. et al., (2001) Selenium deficiency increases the pathology of an influenza virus infection. FASEB J 15(8): 1481-3 Blake, K. (1983) Onion and garlic oils inhibit tumour promotion. Carcinogenesis 4, (8) 1063-1065 Fenwick, G.R. & Hanley, A.B. (1985) The genus Allium. CRC. Rev. Food Sci. Nutr. 22, 199-377 , J.C. et al. (2000) The microaerophilic flagellate Giardia intestinalis: Allium sativum (garlic) is an effective antigiradial. Microbiology 146, 3119-3127 Mirelman, D. et al. (1987) Inhibition of growth of Entamoeba histolytica by allicin, the active principle of garlic extract (Allium sativum). Journal of Infectious Diseases. 156(1) 243-244 Rees, L.P. et al., (1993) A quantitative assessment of the anti- microbial activity of garlic (Allium sativum). World Journal of Microbiology and Biotechnology. 9, 303-307 Ruggeri P. et al., (1991) Chemical composition and antimicrobial activity of two Peruvian plants Boll Soc Ital Biol Sper 67(10- 11):955-60 Souba W.W. (1990) The role of glutamine in maintaining a healthy gut and supporting the metabolic response to injury and infection. J Surg Res 48(4):383-91 Srivastava S.K. et al., (2002) Role of glutathione conjugate efflux in cellular protection against benzo[a]pyrene-7,8-diol-9,10-epoxide- induced DNA damage. Mol Carcinog. 33(3):156-62. Firstly, the company is co-owned by brilliant researchers who have spent years in the trenches as research microbiologists. Quote Link to comment Share on other sites More sharing options...
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