Re: STINKY L-Glutathione!!

[Guest guest]

Hey all,

I mixed the L-Glutathione with my son's other medicines and it reaked like ammonia. Is this the normal smell of it? Yuk! I've just started the chelation process and wonder what the benefit of this supplement is. I'd rather not give it to him!

Thanks,

Eileen

[Guest guest]

Eileen, we stopped giving our son L-Glutathione for the same reason you mentioned. It does smell like ammonia. He is sixteen years old and won't swallow capsules. About two years ago, he was able to tolerate the L-Glutathione when it was mixed with some special vitamin powder mix from our Dan doctor we used back then. I don't remember the name of the vitamin powder. It was awfully expensive. I believe we added cocoa powder to the mix as well. Now, it does not matter what we mix the L-Glutathione with, the smell comes through, and he simply cannot tolerate it. Rose

Re: [ ] STINKY L-Glutathione!!

Hey all, I mixed the L-Glutathione with my son's other medicines and it reaked like ammonia. Is this the normal smell of it? Yuk! I've just started the chelation process and wonder what the benefit of this supplement is. I'd rather not give it to him! Thanks, Eileen =======================================================

[Guest guest]

Eileen,

Glutathione aids the liver in detox processes.

I know that L-Glutathione is composed of amino acids and therefore are nitrogenous, if they are broken down, then I expect it is possible that in some way ammonia is formed, it's smell is almost unmistakable. That said, of the amino acids that make-up Glutathione included is one in particular that could be troublesome, Glutamine, it has as a precursor Glutamic acid which can readily accept ammonia to become Glutamine, I'm not in the know enough to say for certain, but maybe, it is just as easy for it to unload the stuff too. Don't know enough about your protocol, but what you are mixing could be causing this to happen. I think that you are wise to give it a wide berth because ammonia is no good for clear thought. I'm hoping that a chemist (Andy???) might chime-in here as my information source on this is not altogether highly scientific. I furthermore am under the impression that elevated levels of ammonia are present in autistics, and can show up in their urine (something I have noticed too).

This will now go beyond your question Eileen, I'm adding it to try to canvas the views of anyone who may know better.

The issue of elevated ammonia made me look into Glutamine a bit more, I learned that of the possible fates that await it, the above can happen as can conversion to Glutamate, the difference being that it in this case attaches H+ (Hydrogen) instead of ammonia, just suppose here that there is a problem with the mitochondria electron transport chain (I suggest owing to Nicotinamide adenine dinucleotide deficiency or Cytochrome deficiency owing to Lead inhibition of aminolevulinic acid dehydratase) H+ will build up in the cells and maybe Glutamic acid more readily accepts H+ than it does Ammonia/Ammonium. So Glutamate is formed which is an excitory neurotransmitter, and Ammonia is left elevated. I'm presuming that this could contribute to the alkalosis that is (I understand) a frequent finding. The nitrogenous waste products of protein catabolism could in my estimation partly account for difficulties found on a Gluten rich diet, there is plenty of nitrogenous bits holding Gluten products together and without it bread would not possess it's doughy characteristics that make it that bit more palatable than the GF alternatives. Why the increased catabolism if protein? As I tried to explain on the list recently, the sometimes elevated Citric & Succinic and reduced level of Oxo-Glutarate could stem back as far as the electron transport process being inhibited, this (in my view) could cause the Isocitric acid to fail to pass successfully to Oxo-Glutarate which would leave a gap in the Krebs cycle, this can be bridged by using up amino acids, it seems that they must first transform into Glutamic acid. It is at this point that I propose things may be going wrong for Glutamine and instead Glutamate is formed owing to excess H+, in usual instance the Krebs cycle should not have protein as first choice and only uses it as a last resort (similar to fats and Glycogenolysis), but if the products of glycolysis can't pass, then so it seems this remarkable system is able to self rectify. The consequence of this is that one experiences a poor combination of neuromodulators that to me fit in with Autism very well. I have no medical or scientific background and all this could be trash, does anyone know different? Has anyone noticed any improvement during fasting and/or a low protein diet? I'm sure I have heard of this.

Jon .

Re: [ ] STINKY L-Glutathione!!

Hey all, I mixed the L-Glutathione with my son's other medicines and it reaked like ammonia. Is this the normal smell of it? Yuk! I've just started the chelation process and wonder what the benefit of this supplement is. I'd rather not give it to him! Thanks, Eileen =======================================================

[Guest guest]

In a message dated 4/11/01 9:56:21 PM Eastern Daylight Time, Tiredrwe@...

writes:

<<

I mixed the L-Glutathione with my son's other medicines and it reaked like

ammonia. Is this the normal smell of it? Yuk! I've just started the

chelation process and wonder what the benefit of this supplement is. I'd

rather not give it to him!

Thanks,

Eileen >>

I give my son glutathione in a capsule form. I open the capsule and put it

into some juice. It does not have an odor!.

[Guest guest]

Dear Jon,

Whew! Can you give that to me in English? <g> I have read your post more than a few times and trying very hard to understand it. It sounds like you are saying there would be a few reasons why this is not necessarily a good supplement. It aids the liver, however, with the breakdown of the amino acids to ammonia would not be very good. What would be an alternative supplement for L-Glutathione? I have heard whey is another alternative in getting Glutathione. What do you think?

How about melantonin? I have heard of people using this supplement to protect the brain during chelation. It was not recommended to me. Do you or anyone else on the list think that it's a necessary supplement to be using during the chelation process?

Thanks for your time!

Eileen

[Guest guest]

Eileen,

In summary: it may be that the Glutamine part of Glutathione is causing the smell, I went on a bit because it is something I looked into a while back and wanted to canvas the views of others on what I had found. OK, Glutathione helps the liver and I guess that is why you are giving it, what I was trying to point out is that the smell is likely Ammonia, Ammonia is no good for you and that your/our children may have a problem dealing with it as a normal by-product anyway. My speculative conclusion is that Glutamate is made (instead of glutamine) which is an excitory neurotransmitter, it could make them 'stimmy'. Sorry you asked a simple question and got a complicated answer. I know that you were mixing it yourself and were not saying that your child smelled of ammonia, what I tried to do was illustrate what could also be going wrong with Glutathione/Glutamine/Glutamic/Glutamate inside our children.

I don't know much about chelation yet myself which is why I'm here, so I can't advise on it, interesting what you say about melatonin though, I think maybe because it is an antioxidant too.

Jon.

Re: [ ] STINKY L-Glutathione!!

Dear Jon, Whew! Can you give that to me in English? <g> I have read your post more than a few times and trying very hard to understand it. It sounds like you are saying there would be a few reasons why this is not necessarily a good supplement. It aids the liver, however, with the breakdown of the amino acids to ammonia would not be very good. What would be an alternative supplement for L-Glutathione? I have heard whey is another alternative in getting Glutathione. What do you think? How about melantonin? I have heard of people using this supplement to protect the brain during chelation. It was not recommended to me. Do you or anyone else on the list think that it's a necessary supplement to be using during the chelation process? Thanks for your time! Eileen =======================================================

[Guest guest]

Our Kirkman's Reduced L_Glutathione is odor free. Is that what you're using?

My daughter does much better on a high protein diet, and many people have noted that their kids do better while they are ill and fasting.

K.

Has anyone noticed any improvement during fasting and/or a low protein diet? I'm sure I have heard of this?

[Guest guest]

,

No we are not using Kirkman's brand. Are you saying that when it is mixed it does not smell at all?

I would love to have my son on a high protein diet. I just wish I could get more protein in!<g>

Thanks,

Eileen

[Guest guest]

I added the Kirkman L-Glutathione to some other powdered supplements, which I mix with pear baby food, and nobody noticed a change. I opened a capsule and barely noticed an odor.

My daughter uses Seacure too, and it has helped. She's gained weight since starting it, and now eats a reasonable amount of meat (she was eating >1lb. per day). An adult who is very sensitive says she doesn't react to Seacure, which she feels indicates it's not toxic. At one time my daughter ate very little protein, but using digestive enzymes helped her to want to eat more meat. If you haven't already, try to cut the meat up into tiny bits, or make bite sized mini meat balls (meat, pure salt, maybe pure garlic powder) and stew them for an hour so they are tender.

K.

> No we are not using Kirkman's brand. Are you saying that when it is mixed it does not smell at all? > I would love to have my son on a high protein diet. I just wish I could get more protein in!<g>

............

> Although our son eats mainly all protein, we've used Brewer's Yeast and> Seacure in the past for more protein. Seacure is derived from white fish> protein into peptides & amino acids. It also contains omega-3 fatty acids.> Unsure of its mercury content and haven't used since chelation. Wanda

[Guest guest]

Dear K,

I really appreciate all of the suggestions! I am going to try the digestive enzymes and preparing the meat as you said IMMEDIATELY. What a great thing it would be to have my son eat more protein.

Thanks for the Kirkman tip. I got mine somewhere else and will reorder from Kirkman today.

Eileen

[Guest guest]

Dear Eileen, further on the stinky glutathione. In my experience, most autistic

children react badly to glutamine in anything more than a small dose. Most

autistic children have impaired ammonia metabolism pathways (as indicated on

urinary organic acids- Bioscreen) and therefore extra glutamine is diverted to

glutamate. Gut repair needs to be done with other nutrients.

Robyn Cosford

Re: [ ] STINKY L-Glutathione!!

Dear Jon,

Whew! Can you give that to me in English? <g> I have read your post more

than a few times and trying very hard to understand it. It sounds like you

are saying there would be a few reasons why this is not necessarily a good

supplement. It aids the liver, however, with the breakdown of the amino

acids to ammonia would not be very good. What would be an alternative

supplement for L-Glutathione? I have heard whey is another alternative in

getting Glutathione. What do you think?

How about melantonin? I have heard of people using this supplement to

protect the brain during chelation. It was not recommended to me. Do you

or

anyone else on the list think that it's a necessary supplement to be using

during the chelation process?

Thanks for your time!

Eileen

=======================================================

[Guest guest]

Hi - This explanation is very good...pls help me to understand why

glutathione (L-glutathione 100mg capsules) is recommended?Stephnanie

Re: [ ] STINKY L-Glutathione!!

Dear Eileen, further on the stinky glutathione. In my experience, most

autistic children react badly to glutamine in anything more than a small

dose. Most autistic children have impaired ammonia metabolism pathways (as

indicated on urinary organic acids- Bioscreen) and therefore extra glutamine

is diverted to glutamate. Gut repair needs to be done with other nutrients.

Robyn Cosford

Re: [ ] STINKY L-Glutathione!!

Dear Jon,

Whew! Can you give that to me in English? <g> I have read your post

more

than a few times and trying very hard to understand it. It sounds

like you

are saying there would be a few reasons why this is not necessarily a

good

supplement. It aids the liver, however, with the breakdown of the

amino

acids to ammonia would not be very good. What would be an alternative

supplement for L-Glutathione? I have heard whey is another

alternative in

getting Glutathione. What do you think?

How about melantonin? I have heard of people using this supplement to

protect the brain during chelation. It was not recommended to me. Do

you or

anyone else on the list think that it's a necessary supplement to be

using

during the chelation process?

Thanks for your time!

Eileen

=======================================================

[Guest guest]

Jon

What does this mean?

antibodies against Y-GT (enzyme involved with glutamine/GSH and gut

maintenance)

My son is on the diet too . I also didn't want to use the glutamine for fear

of it turning to glutamate..

I know ...I always need you to explain..

Dang complicated stuff....

thanks kelly

[Guest guest]

,

There are various reports on glutathione (Gamma-Glutamylcysteinylglycine) or GSH

for short having different precursors, they generally boil down to the same

thing (N-Acetyl-Cysteine and Cysteine for example), Glutamate and Glutamine are

both attributed with being precursors, I don't think that Glutamate is, I think

it is due to competition for Glutamic acid, Hydrogen wins over Nitrogen and so

there may be potential for a problem here, leaving excessive Glutamate and

Ammonia, not good! What would be good is if Glutamine was there instead, not

because it was supplemented but because the body made it for it's self, and that

same glutamine were to be incorporated into the synthesis of GSH which, to

answer your question, is an anti-oxidant that helps protect DNA and the Liver.

It is a hard nut to crack, I'm sure that glutamine and Glutathione are good,

just so long as they stay that way, I suspect though that Glutamine ends up as

Glutamate and GSH ends up being used, where then it can be renewed, but this is

dependant on NADPH-Cytochrome P-450 Reductase, (which is dependant on NAD),

funny that NAD is also the thing that takes away the Hydrogen that could be

latching on to Glutamic acid, funny too that Hydrogen produced by bad bugs in

the gut can cause symptoms of IBS. I contend that metals are skewing the above

cytochrome, and others, they are essentially chelators, and iron or zinc is

supposed to be there, they are also messing with proper function of NAD(P)H and

if you mess with this lot then you will have problems that are a kin to low GSH,

high Ammonia, high Glutamate and myriad others. Glutathione (IMO) is a good

interim measure, and will help the body be healthier but I think that it has

it's limitations that need to be addressed, shifting the bad metals out has got

to be a good move because it is possible that they are the primary cause. This

is just how I see it, if anyone has anything else on this I'd like to hear,

Robyn, what you said makes much sense, but what other nutrients do you suggest?

Are you angling at attending to mucosal repair to provide a better barrier for

the gut? I think that glutamine is quite relevant esp. if you consider that in

some Coeliac disease gluten promotes antibodies against Y-GT (enzyme involved

with glutamine/GSH and gut maintenance) it is some time since I looked at this

though, yes it may be turned into glutamate, but the alternative is low

glutamine and poor gut integrity.

Jon.

Re: [ ] STINKY L-Glutathione!!

Dear Jon,

Whew! Can you give that to me in English? <g> I have read your post

more

than a few times and trying very hard to understand it. It sounds

like you

are saying there would be a few reasons why this is not necessarily a

good

supplement. It aids the liver, however, with the breakdown of the

amino

acids to ammonia would not be very good. What would be an alternative

supplement for L-Glutathione? I have heard whey is another

alternative in

getting Glutathione. What do you think?

How about melantonin? I have heard of people using this supplement to

protect the brain during chelation. It was not recommended to me. Do

you or

anyone else on the list think that it's a necessary supplement to be

using

during the chelation process?

Thanks for your time!

Eileen

=======================================================

[Guest guest]

Hi

I think Kirkmans is coming out with a glutathione cream that will be

absorbed through the skin.. Much like the Magnesium sulfate. ( epsom salts baths

)... I made my own by using a Reduced L-glutathione capsule with coconut oil ..

Does anyone have any ideas about this.? I don't really know if it works...

I was always under the impression that it was a worthless oral suppliment

because it would quickly lose it potency...

kelly

[Guest guest]

Thanks Jon- My son's ammonia in plasma is high so this part of your

explanation really sticks out to me...My appt. with a DAN Dr. isn't until

mid Aug. so I got some input at the DAN conference and L-Glutathione was

recommended to me as one of the supplements to give . Dr. Higgins

looked at all the tests I had done before the suggestion, but the potential

for problems wasn't mentioned and we really don't have anyone monitoring us

till the Aug. visit so...dilema?!?!?! to give or not to give ...that's the

question?!?!? Is there any way I would know if it was leaving excessive

glutamate & ammonia?- We already have very acidic smelling BM's. (We start

GFCF this week though so maybe that will help his " confused little system "

some.) Any more input???

Re: [ ] STINKY L-Glutathione!!

,

There are various reports on glutathione (Gamma-Glutamylcysteinylglycine)

or GSH for short having different precursors, they generally boil down to

the same thing (N-Acetyl-Cysteine and Cysteine for example), Glutamate and

Glutamine are both attributed with being precursors, I don't think that

Glutamate is, I think it is due to competition for Glutamic acid, Hydrogen

wins over Nitrogen and so there may be potential for a problem here, leaving

excessive Glutamate and Ammonia, not good! What would be good is if

Glutamine was there instead, not because it was supplemented but because the

body made it for it's self, and that same glutamine were to be incorporated

into the synthesis of GSH which, to answer your question, is an anti-oxidant

that helps protect DNA and the Liver. It is a hard nut to crack, I'm sure

that glutamine and Glutathione are good, just so long as they stay that way,

I suspect though that Glutamine ends up as Glutamate and GSH ends up being

used, where then it can be renewed, but this is dependant on

NADPH-Cytochrome P-450 Reductase, (which is dependant on NAD), funny that

NAD is also the thing that takes away the Hydrogen that could be latching on

to Glutamic acid, funny too that Hydrogen produced by bad bugs in the gut

can cause symptoms of IBS. I contend that metals are skewing the above

cytochrome, and others, they are essentially chelators, and iron or zinc is

supposed to be there, they are also messing with proper function of NAD(P)H

and if you mess with this lot then you will have problems that are a kin to

low GSH, high Ammonia, high Glutamate and myriad others. Glutathione (IMO)

is a good interim measure, and will help the body be healthier but I think

that it has it's limitations that need to be addressed, shifting the bad

metals out has got to be a good move because it is possible that they are

the primary cause. This is just how I see it, if anyone has anything else

on this I'd like to hear, Robyn, what you said makes much sense, but what

other nutrients do you suggest? Are you angling at attending to mucosal

repair to provide a better barrier for the gut? I think that glutamine is

quite relevant esp. if you consider that in some Coeliac disease gluten

promotes antibodies against Y-GT (enzyme involved with glutamine/GSH and gut

maintenance) it is some time since I looked at this though, yes it may be

turned into glutamate, but the alternative is low glutamine and poor gut

integrity.

Jon.

Re: [ ] STINKY L-Glutathione!!

Dear Jon,

Whew! Can you give that to me in English? <g> I have read your

post

more

than a few times and trying very hard to understand it. It sounds

like you

are saying there would be a few reasons why this is not

necessarily a

good

supplement. It aids the liver, however, with the breakdown of the

amino

acids to ammonia would not be very good. What would be an

alternative

supplement for L-Glutathione? I have heard whey is another

alternative in

getting Glutathione. What do you think?

How about melantonin? I have heard of people using this

supplement to

protect the brain during chelation. It was not recommended to me.

Do

you or

anyone else on the list think that it's a necessary supplement to

be

using

during the chelation process?

Thanks for your time!

Eileen

=======================================================

[Guest guest]

Can or somebody 'splain this one to me??? I've had glutamine

recommended to me as something that helps heal the gut:

> I also didn't want to use the glutamine for fear of it turning to

> glutamate..

Terri

[Guest guest]

Terri

I try to s'plain to ya.. I just don't know if it will be very clear.. It

started when I was reading about MSG and its effects.. Glutamine is a

precurser to glutamate . There is something called a glutamate transport

protein and if these don't soak up excess glutamine then they can lead to

excess glutamate which can kill neurons . This is the kind of thing I

remember from reading and took it to heart.. If you'd like I could delve

deeper into my MSG book. I haven't had this out for a long time so mainly I

remember be wary of glutamine for this particular reason...,

Now if it is not turning to glutamate then it can be just fine and do

exactly what you said.. Heal the gut.. I just didn't want to take any

chances... Jon you can always step in here..... kelly

[Guest guest]

,

Not to mislead you, it is only some coeliacs, and I was more on the track of

metals doing the similar by way of inhibiting rather than by inducing antibodies

that also recognise Y-GT. So it seems there is someone who thinks alike, Bernie

re-posted " Re: indicators of mercury toxicity " today and I note that the same

enzyme is apparantly effected by mercury. Y-GT and GGT are one and the same,

just a shame that all medical terms are not universal, it makes things more

difficult. It is a while since I looked into it, but from what I can remember,

GGT is very important in the maintenence of the gut wall, sorry I can't be

specific, that would take me a couple of months, it's something like when

Glutathione is synthesised, before it becomes glutathione it can give-up

glutamine, and this is to do with GGT, I'm confidant in saying though that if

you have identified mercury as a problem then the odds are that things will

improve as mercury shifts out, and perhaps it is better not to worry too much

about the science bit that you have no control over anyway except to remove

mercury. Interesting that you have made a similar conclusion about glutamine

and glutamate, did you read it somewhere? I was worried that it might just seem

like scaremongering when I said it. I do think that there is a place for

glutamine, just that it may be a good idea to monitor behaviour, and adjust

accordingly. I suppose that it is worth a try (it's been shown to increase IQ of

mentaly deficient children and help with senility & schizophrenia). It's

precursor: Glutamic acid is used primarily as a brain fuel and picks up excess

ammonia (I'm quoting here), but I have no experience of using glutamic acid, I

don't even know if they sell it, seems to make some sense though that if you

give a supplement 'loaded' with ammonia to someone who may already have a

problem with ammonia then it could make things worse.

Jon.

RE: [ ] STINKY L-Glutathione!!

Jon

What does this mean?

antibodies against Y-GT (enzyme involved with glutamine/GSH and gut

maintenance)

My son is on the diet too . I also didn't want to use the glutamine for fear

of it turning to glutamate..

I know ...I always need you to explain..

Dang complicated stuff....

thanks kelly

[Guest guest]

,

You mentioned coconut oil, well I thought I'd add that according to Dr. Rosemary

Waring (Sulphur whiz), coconut oil actually activates TPST (Tyrosyl-protein

sulphotransferase) which is said to have low activity in autism, you may have

compounded a 'wonder-drug', did you have any good results?

Jon.

RE: [ ] STINKY L-Glutathione!!

Hi

I think Kirkmans is coming out with a glutathione cream that will be

absorbed through the skin.. Much like the Magnesium sulfate. ( epsom salts baths

)... I made my own by using a Reduced L-glutathione capsule with coconut oil ..

Does anyone have any ideas about this.? I don't really know if it works...

I was always under the impression that it was a worthless oral suppliment

because it would quickly lose it potency...

kelly

[Guest guest]

,

I can't say for sure that this is the case, this was prompted originally by the

observation that glutathione smells of ammonia when mixed with other

supplements, I put forth a case that it probably was and tried to explain why.

Please understand that I'm a fellow parent only, and on this one I think I would

consider the responses others have observed, I think that it is likely that

Glutathione and Glutamine are going to be depressed, and so there should be some

benefit from it, the trade-off for the benefit will/could be elevated ammonia

and maybe glutamate, it is something I would try, but with caution. Look out for

sore bottoms, smell and behaviour.

I would expect your own Doctor to run tests (urea) which could help point to the

cause, good chance (IMO) that it is because he is running on protein instead of

glucose. We all make ammonia and deal with it, it is a waste product and

problems come from making too much or excreting too little, that is what the

tests should help with.

Jon.

Re: [ ] STINKY L-Glutathione!!

Dear Jon,

Whew! Can you give that to me in English? <g> I have read your

post

more

than a few times and trying very hard to understand it. It sounds

like you

are saying there would be a few reasons why this is not

necessarily a

good

supplement. It aids the liver, however, with the breakdown of the

amino

acids to ammonia would not be very good. What would be an

alternative

supplement for L-Glutathione? I have heard whey is another

alternative in

getting Glutathione. What do you think?

How about melantonin? I have heard of people using this

supplement to

protect the brain during chelation. It was not recommended to me.

Do

you or

anyone else on the list think that it's a necessary supplement to

be

using

during the chelation process?

Thanks for your time!

Eileen

=======================================================

[Guest guest]

JON:

Didn't you know I am a mad scientist ? HA<HA<HA I am familiar with Rosemary

Waring and sulfation.. Is this (Tyrosyl-protein sulphotransferase) the same???

Could you give me a run down on what it is and what it does?? I know I ask a

lot. I'll let you know if it works after I go mix up my next batch in my

lab...HA<HA HA>>>>> kelly

You mentioned coconut oil, well I thought I'd add that according to Dr.

Rosemary Waring (Sulphur whiz), coconut oil actually activates TPST

(Tyrosyl-protein sulphotransferase) which is said to have low activity in

autism, you may have compounded a 'wonder-drug', did you have any good

results?

Jon.

[Guest guest]

Thanks Jon- Your input is very helpful...we'll look for a Dr. who might

consider these tests before our DAN Dr. appt. in a few months.

Re: [ ] STINKY L-Glutathione!!

,

I can't say for sure that this is the case, this was prompted originally

by the observation that glutathione smells of ammonia when mixed with other

supplements, I put forth a case that it probably was and tried to explain

why. Please understand that I'm a fellow parent only, and on this one I

think I would consider the responses others have observed, I think that it

is likely that Glutathione and Glutamine are going to be depressed, and so

there should be some benefit from it, the trade-off for the benefit

will/could be elevated ammonia and maybe glutamate, it is something I would

try, but with caution. Look out for sore bottoms, smell and behaviour.

I would expect your own Doctor to run tests (urea) which could help point

to the cause, good chance (IMO) that it is because he is running on protein

instead of glucose. We all make ammonia and deal with it, it is a waste

product and problems come from making too much or excreting too little, that

is what the tests should help with.

Jon.

Re: [ ] STINKY L-Glutathione!!

Dear Jon,

Whew! Can you give that to me in English? <g> I have read

your

post

more

than a few times and trying very hard to understand it. It

sounds

like you

are saying there would be a few reasons why this is not

necessarily a

good

supplement. It aids the liver, however, with the breakdown of

the

amino

acids to ammonia would not be very good. What would be an

alternative

supplement for L-Glutathione? I have heard whey is another

alternative in

getting Glutathione. What do you think?

How about melantonin? I have heard of people using this

supplement to

protect the brain during chelation. It was not recommended to

me.

Do

you or

anyone else on the list think that it's a necessary supplement

to

be

using

during the chelation process?

Thanks for your time!

Eileen

=======================================================

[Guest guest]

Another person who's super-expert on sulfation stuff is Lang, the

guy who owns Brainchild Nutritionals. He's a great resource, so if you

ever want the real detailed into on this, talk to him! He doesn't post

all that much, but his site is www.brainchildnutritionals.com and next week

we'll be putting up an article he wrote for the Durham conference last year

about his theory on the causal factors of autism. I do web work for him,

on a trade basis.

Terri

At 09:15 PM 5/21/01 +0100, you wrote:

>Professor ,

>

>I'm not ultra clear on this one myself, Phenol-Sulphur-Transferase seems

>to have gone out of the window in favour of TPST, as the one that is

>predominantly inhibited in ASD, I scribbled down some notes just as fast

>as I could, but want to get hold of the recording and go over it

>again, What I wrote is this: " catalyses the addition of sulphate to

>Tyrosine residues. " and " TPST has low activity in autism. " and " What can

>be done about it? Fatty acids (coconut oil),fish oils can activate this

>enzyme. " the point was made that there are multiple deficiencies (Sulphite

>Oxidase for example) and that these can be attributed as being a cause of

>the symptoms of ASD. Once I have found out more I'll try to share

>it. Something that did surprise me is that Flavonoids can inhibit the

>sulphurtransferases which sulphate amines and phenols, and yet some can be

>activated by fatty acids and by certain flavonoids.

>I have to point out though that Owens has a much better idea about

>this than me, I read up on previous reports, but have not made it my

>'thing', I just try to keep up to date on it, I did not manage to take it

>in well enough on the day.

>Don't get much Lab time anymore, my wife treats the place like it is a

>kitchen or something, even my specimen fridge is full of food!

>

>Igor.

> Re: [ ] STINKY L-Glutathione!!

>

>

> JON:

> Didn't you know I am a mad scientist ? HA<HA<HA I am familiar with

> Rosemary Waring and sulfation.. Is this (Tyrosyl-protein

> sulphotransferase) the same??? Could you give me a run down on what it is

> and what it does?? I know I ask a lot. I'll let you know if it works

> after I go mix up my next batch in my lab...HA<HA HA>>>>> kelly

>

> You mentioned coconut oil, well I thought I'd add that according to Dr.

> Rosemary Waring (Sulphur whiz), coconut oil actually activates TPST

> (Tyrosyl-protein sulphotransferase) which is said to have low activity in

> autism, you may have compounded a 'wonder-drug', did you have any good

> results?

>

> Jon.

>

>

> =======================================================

>

[Guest guest]

Professor ,

I'm not ultra clear on this one myself, Phenol-Sulphur-Transferase seems to have

gone out of the window in favour of TPST, as the one that is predominantly

inhibited in ASD, I scribbled down some notes just as fast as I could, but want

to get hold of the recording and go over it again, What I wrote is this:

" catalyses the addition of sulphate to Tyrosine residues. " and " TPST has low

activity in autism. " and " What can be done about it? Fatty acids (coconut

oil),fish oils can activate this enzyme. " the point was made that there are

multiple deficiencies (Sulphite Oxidase for example) and that these can be

attributed as being a cause of the symptoms of ASD. Once I have found out more

I'll try to share it. Something that did surprise me is that Flavonoids can

inhibit the sulphurtransferases which sulphate amines and phenols, and yet some

can be activated by fatty acids and by certain flavonoids.

I have to point out though that Owens has a much better idea about this

than me, I read up on previous reports, but have not made it my 'thing', I just

try to keep up to date on it, I did not manage to take it in well enough on the

day.

Don't get much Lab time anymore, my wife treats the place like it is a kitchen

or something, even my specimen fridge is full of food!

Igor.

Re: [ ] STINKY L-Glutathione!!

JON:

Didn't you know I am a mad scientist ? HA<HA<HA I am familiar with Rosemary

Waring and sulfation.. Is this (Tyrosyl-protein sulphotransferase) the same???

Could you give me a run down on what it is and what it does?? I know I ask a

lot. I'll let you know if it works after I go mix up my next batch in my

lab...HA<HA HA>>>>> kelly

You mentioned coconut oil, well I thought I'd add that according to Dr.

Rosemary Waring (Sulphur whiz), coconut oil actually activates TPST

(Tyrosyl-protein sulphotransferase) which is said to have low activity in

autism, you may have compounded a 'wonder-drug', did you have any good

results?

Jon.

=======================================================