Re: EN Nodules Leave Dents!

[Guest guest]

LOL! I had a funny thought! If only I could get EN on my hips and

love handles....then I wouldn't have to think about liposuction!

*HA*

Why oh why can't they come and destruct that nasty fat I don't

want?!?!? )

Thanks for the info, and AJ! This group is the greatest!!

~Ellen

>

> Hi Ellen and AJ,

>

> The indentation is caused by destruction of the fat layer. I know

that I

> have lost the fat layer where my lumps used to be,[ on the lower,

inner

> area above the ankle]. I never got the indentations though. It only

> affects my left leg which I call my " EN Leg " , and since I have

thin

> legs, it isn't too obvious. But if you compare my legs, the EN leg

is

> thinner. I am hoping since the fat is gone, maybe the EN will not

come

> back. My thinking is if EN is inflammation of the fat and the fat

is

> destroyed, maybe the EN will stop. My remissions are lasting

longer in

> any event.

> Here is an

> EN Link <http://www.medicinenet.com/erythema_nodosum/article.htm>

> Erythema nodosum can be self-limited and resolve on its own in 3

to 6

> weeks. Upon resolution, it may leave only a temporary bruised

appearance

> or leave a chronic indentation in the skin where the fatty layer

has

> been injured.

>

> The loss of fat is called

>

> Lipoatrophy

>

<http://www.merckmedicus.com/ppdocs/us/hcp/content/white/chapters/whi

te-\

> ch-018-s004.htm>

>

>

> DISORDERS OF FAT AND SUBCUTANEOUS TISSUES

>

> Lipoatrophy

>

> Lipoatrophy may be localized, partial (upper trunk) or total;

it may

> occur in isolation or associated with atrophy of other deeper

structures

> (such a panatrophy).

>

> Localized areas of lipoatrophy may occur in the following

> situations:

> • injection sites: insulin lipoatrophy (Fig. 18.43

>

<http://www.merckmedicus.com/ppdocs/us/hcp/content/white/chapters/whi

te-\

> ch-018-s004.htm#F018043> ), intralesional/depot steroid injections

(Figs

> 18.44

>

<http://www.merckmedicus.com/ppdocs/us/hcp/content/white/chapters/whi

te-\

> ch-018-s004.htm#F018044> and 18.45

>

<http://www.merckmedicus.com/ppdocs/us/hcp/content/white/chapters/whi

te-\

> ch-018-s004.htm#F018045> ); • postinflammatory: following

> panniculitis; • idiopathic: thighs (lipoatrophia

> semicircularis, possibly related to pressure), abdomen (centrifugal

> lipodystrophy, Fig. 18.46

>

<http://www.merckmedicus.com/ppdocs/us/hcp/content/white/chapters/whi

te-\

> ch-018-s004.htm#F018046> ), and others.

>

> Maybe removing the " bad tissue " with a cannula like the ones they

use to

> suck out fat in liposuction, might " cure EN in some cases like mine

> where the same spot kept getting inflammed. But this has never been

> done, to my knowledge, and I doubt any doctor would try it.

>

> Love,

>

>

[Guest guest]

Hi,

It is also a very similar situation with Skin and Subcutaneous

Sarcoidosis. Both leave dents or indentations when they go away.

Sarcoidosis can also affect the underlying dermal and vascular system

with the inflammation, leading to loss of blood flow to the tissue.

Loss of blood flow causes the loss of the tissue. Unfortunately, the

long term result is the same as EN, those fantastic beauty marks in the

skin that never go away.

Wayne