Inheritance is a mystery

[Guest guest]

CMT is a strange disease. My older brother and I are wheelchair users

and have a difficult time walking at all. Our younger brother has it

but works in a hospital and is on his feet all day, but his feet are

getting progressively worse. My sister has not been diagnosed but she

probaly also has it, but like my brother she works in a hospital and

is on her feet all day.

And that is it! Neither of our parents showed any signs. None of

their brothers or sisters showed any signs. I have a whole lot of

cousins on my mom's side of the family and none of them have CMT. I

don't have any family on my dad's side still around that I know of but

none of them seemed to have it while they were living. So far none of

my nieces and nephews have shown signs, even though some of them are

in their 20s and 30s. It just hit our generation.

The doctors have asssumed it is Type 4, where both parents carry the

recessive gene. It is common among families where there has been

intermarriage. I have traced both parent's ancestry at leat 4

generations and in one case 8 generations and have yet to find a

common ancestor, although things get murky when I get back to Ireland

and the records are not clear. CMT has been a mystery in our family.

I hope this helps make things more murky. LOL

Tom