Successful Completion Evaluation And Validation Of Human Neural Crest Stem Cell

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Successful Completion Evaluation And Validation Of Human Neural Crest

Stem Cell Line - Stem Cell Research Institute, Inc

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U.S. BioDefense (OTC Bulletin Board: UBDE) is pleased to announce

today that it has successfully completed the evaluation and

validation of its human neural crest stem cells as a part of its

agreement with the University of British Columbia.

Director of Research, Dr. Cyndi Chen, Ph.D. stated " This is exciting

news for us and the medical community. The possibilities of

developing neural crest stem cell therapies and treatments for a

number of degenerative diseases give hopes to those who suffer from

these debilitating diseases. "

Having passed the initial validation phase, U.S. BioDefense, Inc. is

now working toward a full licensing relationship and will begin pre-

clinical analysis of how this cell line can be utilized. Currently,

the company is considering investigating the stem cells applications

in combating ALS and Parkinson's disease. U.S. BioDefense, Inc. joins

StemCells, Inc. in the fight to find a therapeutic treatment for

neurodegenerative diseases in the United States.

On September of 2005, U.S. BioDefense, Inc. received its first stem

cell line. The stem cell line is part of an option to license world

patent application WO 03/054202 A1 and US patient application

5,958,767 entitled " Generation of Human Neural Crest Stem Cell Line

and Its Utilization in Human Transplantation " and related

applications with the University of British Columbia. The line was

developed by Dr. Seung Kim and has potential applications in the

development of therapeutic treatments for a variety of

neurogenerative diseases.

CEO Chin stated that, " We are pleased to announce to our

shareholders the completion of the evaluation phase and look to move

forward on completing the negotiation to acquire this amazing

technology. Currently, the existence of immature multi-potent stem

cells has been identified in the embryonic and adult human brain and

several groups have generated stable, perpetual neural stem cell

lines that were utilized for cell replacement or gene transfer

therapies in animal models of human neurological disorders. To this

end, we will continue our progress to investigate the potentials of

these cells for future clinical prospects. "