Dr Megson's vitamin A and Urecholine/Bethanecol protocol

[Guest guest]

Hi Anita and others,

as vitamin A protocol has been mentioned here a lot I thought you might be interested in this write-up on Megson's work.

(for what it is worth... it seems to me this protocol goes towards

repairing damage caused by viruses/toxins, not so much it being an

antiviral protocol as such...)

G-alpha Protein Abnormalities - The Megson Protocol: Vitamin A and Bethanecol (Urecholine)

In 1999 Dr. Megson of the University of Virginia presented her

research findings at the Defeat Autism Now! (DAN!) Conference. Dr.

Megson discovered that G-alpha protein receptors (LINKED TO POTASSIUM / CALCIUM CHANNELS?!)

on the surface of cells were disrupted in autistic children with

genetic susceptibilities to this defect. G proteins are cell surface

molecules which, when activated, transmit signals to the inside of the

cell that in turn cause a variety of chemical reactions to occur.

The abnormal G-alpha protein receptors found in autistic children were

associated with defective receptors for retinoids (vitamin A and its

analogs) in the brain and intestinal tract. Vitamin A is necessary for

vision, the prevention of night blindness (nb CACNA MUTATION in New Zealand monogenetic Calcium Channel syndrome causing night blindness and autism!!!),

sensory perception, language processing and attention. Children of

families with a history of night blindness, pseudo-hypo-parathyroidism

or adenoma (benign tumor) of the thyroid or pituitary gland were found

to be more prone to this G-alpha protein abnormality.

Dr. Megson found a connection between the measles and pertussis vaccinations and G-alpha protein defects.

She discovered that the pertussis toxin found in the DPT vaccine

(normally injected at 2, 4, 6 and 18 months of age) separates the

G-alpha protein from retinoid (vitamin A) receptors. It also promotes a

chronic auto-immune reaction (monocytic [a type of white cell]

infiltration) of the deep layer (lamina propria) in the gut lining

(mucosa).

This in turn leads to a chemical disconnect of the G-alpha protein

pathways and the regulating retinoid (Vitamin A) switch, which results

in the non-specific branch of the immune system being turned on. Unfortunately, without the proper functioning of the retinoid switch the immune system canÕt be turned off!!

The measles virus, part of the MMR vaccination, also plays a role in

the g-alpha protein problem. Measles vaccination is associated with

lower vitamin A levels and vitamin A in its natural form (cis-vitamin

A) is necessary for activating the retinoid receptors.

The antibodies to the measles virus also disrupt the Òmolecular glueÓ

that connects one cell to another and which is so essential

cell-to-cell communication and gut mucosal integrity. The absorption of

vitamin A from the intestinal tract requires an intact gut mucosal

surface, the right acidity (pH) and the presence of bile.

Dr. Megson also found that there is an important difference between

natural (cis-retinoic acid) Vitamin A (found in fish oils) and the

synthetic vitamin A palmitate found in infant formulas and commercial

vitamins. The artificial Vitamin A palmitate binds the free G-alpha

protein and by so doing deactivates the Òoff switchÓ for multiple

metabolic pathways involved in vision, cell growth, hormonal regulation

and the metabolism of lipids (fats), proteins and glycogen, a storage

form of glucose.

Fortunately, Dr. Megson was able to find a simple and inexpensive

solution for this biochemical dilemma: cod liver oil and Urocholine

(Bethanecol). This protocol has been used in over 500 patients without

any side effects. In the first phase loading with vitamin A in its

natural form, preferably from toxin-free cod liver oil) is started and

continued for 2-3 months. This is followed by the introduction of

Bethanecol, a parasympathetic nervous system stimulator that promotes

the utilization of vitamin A in cells.

The treatment is especially effective for those experiencing any of

the following symptoms: malabsorption, divergent gaze, speech delay,

dry skin, poor social skills, night blindness, soft stools and dry eyes.

The recommended dosage of mercury & dioxin-free cod liver oil is as follows:

20-30 lbs 850-1250 IU

31-45 lbs 2500 IU

46-75 lbs 3750 IU

76-125 lbs 5000 IU

>125 lbs 7500 IU

Good brands of cod liver oil include Nordic Naturals, Eskimo 3, Pharmax, CarlsonÕs and KirkmanÕs

The bethanecol comes as thin, scored 10 mg tablets. They can be halved

or quartered or crushed and dissolved in water. Bethanecol remains

stable in a watery solution for at least 30 days. DonÕt start the

Bethanecol until the child has been on the cod liver oil for at least

two months. Continue the cod liver oil while on the Bethanecol.

Suggested oral daily dosages of bethanecol are as follows:

Less Than 5 years start with 2.5 mg

5-8 years start with 5-7.5 mg

Above 8 years start with 10 mg

Maximum dosage is 12.5 mg

If the initial dosage of bethanecol doesnÕt result in signs of improved

functioning then the dose may be increased by increments of 2.5 mg per

dose to maximum of 12.5 mg. A sign of too much bethanecol is

constricted pupils.

Hope this helps someone,

Natasa