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Re: Pfizer stops testing of newest statin...

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Posted

>

> Read this... I just saw it on news.

>

> http://tinyurl.com/y26258

>

> Ed

>

Yeah, the cardiologist wanted me on that. I passed. Looks like a smart

decision to pass.

Note from Ed: Very good decision on your part. The cardiologist was

being PAID to have his patients on the test for Pfizer. No concern for the

patient at all... just think about it. All of us are nothing more to the

medical and pharmaceutical companies than FREE lab rats. I am just wondering,

when the cardiologist wanted you to start taking this new drug did he tell you

it was being tested and was not approved by the FDA yet? Or did he tell you

what the side effects were and that people had already begun to die during the

tests?

If anyone continues to take the word of a dr. with blind value needs to seek a

few hours on his back on a couch. LOL

I have no faith in drs any more. Just recently my wife had a severe headache

that last for 12 days. She is a nurse in a hospital here in the labor and

delivery wing. She received a flu shot on Wednesday on Thursday afternoon she

got a whopper of a headache. Instead of going away after some Excedrin it got

worse. Saturday morning I took her to ER at the hospital. We were there for 8

hours to try and stop the pain. After using 4 different pain IV's they sent us

home with a prescription for MORPHINE where she took it every day for the next 9

days until the pain went away. No other pain reliever even this new DHE which

is supposed to relieve a migraine within minutes did not work.

Bottom line ... it is now suspected that gentically she reacted violently to the

flu shot and her regular dr. now believes that she had a bout of spinal

meningitis. She could have died from this flu shot and nothing was being done

to explore the cause. She did have a CT scan in ER and showed it to be

negative.

So after it was all done it is suspected that she had spinal meningitis and she

was being treated for a migraine in ER for 8 hours.

I honestly am beginning to have no faith in the medical community other than

passinng out prescriptions.

just my two cents...sorry!!!

Posted

Interesting. I don't know why 51 deaths for Lipitor is considered normal compared with 82 deaths for the new drug. I wonder if they ever compared both with the sugar-pill group, which I believe would have a much lower number.HX Pfizer stops testing of newest statin...

Read this... I just saw it on news.

http://tinyurl. com/y26258

Ed

Posted

I wonder why this study didn't raise questions about Lipitor's safety.

Gene

Note from Ed: I wondered the same thing. I am hoping that this will

put some more concern about all this crap from the general public. I

have only seen in on so far.. not on TV nor radio or in a news

paper yet. It may not be sexy enough to be news worthy.

At 09:11 PM 12/2/2006, you wrote:

>Read this... I just saw it on news.

>

>http://tinyurl.com/y26258

>

>Ed

Posted

I saw it on TV this morning...not sure what

station...either CBS or NBC...I hope I hear it again!

This news certainly merits more broadcasts!

Jan

--- Gene Wolfe <genew@...> wrote:

> I wonder why this study didn't raise questions about

> Lipitor's safety.

>

> Gene

>

> Note from Ed: I wondered the same thing. I am

> hoping that this will

> put some more concern about all this crap from the

> general public. I

> have only seen in on so far.. not on TV nor

> radio or in a news

> paper yet. It may not be sexy enough to be news

> worthy.

>

> At 09:11 PM 12/2/2006, you wrote:

> >Read this... I just saw it on news.

> >

> >http://tinyurl.com/y26258

> >

> >Ed

>

>

________________________________________________________________________________\

____

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Learn how on Small Business.

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Posted

I saw it on TV this morning...not sure what

station...either CBS or NBC...I hope I hear it again!

This news certainly merits more broadcasts!

Jan

--- Gene Wolfe <genew@...> wrote:

> I wonder why this study didn't raise questions about

> Lipitor's safety.

>

> Gene

>

> Note from Ed: I wondered the same thing. I am

> hoping that this will

> put some more concern about all this crap from the

> general public. I

> have only seen in on so far.. not on TV nor

> radio or in a news

> paper yet. It may not be sexy enough to be news

> worthy.

>

> At 09:11 PM 12/2/2006, you wrote:

> >Read this... I just saw it on news.

> >

> >http://tinyurl.com/y26258

> >

> >Ed

>

>

________________________________________________________________________________\

____

Want to start your own business?

Learn how on Small Business.

http://smallbusiness./r-index

Posted

>

> Interesting. I don't know why 51 deaths for Lipitor is considered

normal compared with 82 deaths for the new drug. I wonder if they ever

compared both with the sugar-pill group, which I believe would have a

much lower number.

------- reply follows--------

Great question!

If they did not have a placebo control, it suggests the test were

basically rigged.

This is the kind of thing that should be investigated by the FDA and

congress.

Marty

Posted

Ed Gundy wrote:

>

> Read this... I just saw it on news.

>

> http://tinyurl. com/y26258 <http://tinyurl.com/y26258>

>

> Ed

>

>

Hi Ed,

Pfieser hold the patent to ECT 216 a drug that is already proven to

reverse arterial blockages and cure most heart disease but they have

been withholding it from the FDA trials.

Read this! It is all about the money!!

http://www.drugdevelopment-technology.com/projects/etc/

Joe

Posted

Ed Gundy wrote:

>

> Read this... I just saw it on news.

>

> http://tinyurl. com/y26258 <http://tinyurl.com/y26258>

>

> Ed

>

>

Hi Ed,

Pfieser hold the patent to ECT 216 a drug that is already proven to

reverse arterial blockages and cure most heart disease but they have

been withholding it from the FDA trials.

Read this! It is all about the money!!

http://www.drugdevelopment-technology.com/projects/etc/

Joe

Posted

Tom wrote:

>

>

>

> >

> > Read this... I just saw it on news.

> >

> > http://tinyurl. com/y26258 <http://tinyurl.com/y26258>

> >

> > Ed

> >

>

> Yeah, the cardiologist wanted me on that. I passed. Looks like a smart

> decision to pass.

>

> Note from Ed: Very good decision on your part. The cardiologist was

> being PAID to have his patients on the test for Pfizer. No concern for

> the patient at all... just think about it. All of us are nothing more

> to the medical and pharmaceutical companies than FREE lab rats. I am

> just wondering, when the cardiologist wanted you to start taking this

> new drug did he tell you it was being tested and was not approved by

> the FDA yet? Or did he tell you what the side effects were and that

> people had already begun to die during the tests?

>

> If anyone continues to take the word of a dr. with blind value needs

> to seek a few hours on his back on a couch. LOL

>

> I have no faith in drs any more. Just recently my wife had a severe

> headache that last for 12 days. She is a nurse in a hospital here in

> the labor and delivery wing. She received a flu shot on Wednesday on

> Thursday afternoon she got a whopper of a headache. Instead of going

> away after some Excedrin it got worse. Saturday morning I took her to

> ER at the hospital. We were there for 8 hours to try and stop the

> pain. After using 4 different pain IV's they sent us home with a

> prescription for MORPHINE where she took it every day for the next 9

> days until the pain went away. No other pain reliever even this new

> DHE which is supposed to relieve a migraine within minutes did not work.

>

> Bottom line ... it is now suspected that gentically she reacted

> violently to the flu shot and her regular dr. now believes that she

> had a bout of spinal meningitis. She could have died from this flu

> shot and nothing was being done to explore the cause. She did have a

> CT scan in ER and showed it to be negative.

>

> So after it was all done it is suspected that she had spinal

> meningitis and she was being treated for a migraine in ER for 8 hours.

>

> I honestly am beginning to have no faith in the medical community

> other than passinng out prescriptions.

>

> just my two cents...sorry! !!

>

>

Ed,

My wife also had one of those severe headaches. After all the tests and

spinal taps, they sent her home. The next day she went to her

Chiropractor. Turns out it all was caused by a pinched nerve in her

neck. He adjusted her neck...headache gone!!

Joe

Posted

Tom wrote:

>

>

>

> >

> > Read this... I just saw it on news.

> >

> > http://tinyurl. com/y26258 <http://tinyurl.com/y26258>

> >

> > Ed

> >

>

> Yeah, the cardiologist wanted me on that. I passed. Looks like a smart

> decision to pass.

>

> Note from Ed: Very good decision on your part. The cardiologist was

> being PAID to have his patients on the test for Pfizer. No concern for

> the patient at all... just think about it. All of us are nothing more

> to the medical and pharmaceutical companies than FREE lab rats. I am

> just wondering, when the cardiologist wanted you to start taking this

> new drug did he tell you it was being tested and was not approved by

> the FDA yet? Or did he tell you what the side effects were and that

> people had already begun to die during the tests?

>

> If anyone continues to take the word of a dr. with blind value needs

> to seek a few hours on his back on a couch. LOL

>

> I have no faith in drs any more. Just recently my wife had a severe

> headache that last for 12 days. She is a nurse in a hospital here in

> the labor and delivery wing. She received a flu shot on Wednesday on

> Thursday afternoon she got a whopper of a headache. Instead of going

> away after some Excedrin it got worse. Saturday morning I took her to

> ER at the hospital. We were there for 8 hours to try and stop the

> pain. After using 4 different pain IV's they sent us home with a

> prescription for MORPHINE where she took it every day for the next 9

> days until the pain went away. No other pain reliever even this new

> DHE which is supposed to relieve a migraine within minutes did not work.

>

> Bottom line ... it is now suspected that gentically she reacted

> violently to the flu shot and her regular dr. now believes that she

> had a bout of spinal meningitis. She could have died from this flu

> shot and nothing was being done to explore the cause. She did have a

> CT scan in ER and showed it to be negative.

>

> So after it was all done it is suspected that she had spinal

> meningitis and she was being treated for a migraine in ER for 8 hours.

>

> I honestly am beginning to have no faith in the medical community

> other than passinng out prescriptions.

>

> just my two cents...sorry! !!

>

>

Ed,

My wife also had one of those severe headaches. After all the tests and

spinal taps, they sent her home. The next day she went to her

Chiropractor. Turns out it all was caused by a pinched nerve in her

neck. He adjusted her neck...headache gone!!

Joe

Posted

Pfizer may have stopped trials on torcetrapib combo, but..."Pfizer is trying to convince Wall Street that it has a robust pipeline, following a series of pipeline setbacks in recent years. Among other problems, Pfizer pulled out of an effort to develop a sleeping pill called Indiplon after it ran into problems at the FDA, and just this week it discontinued a schizophrenia drug pact. Meanwhile, the company said that the antibiotic Dalbavancin, which has been delayed at the FDA, should be approved in the first half of 2007. Another drug that has been delayed because of manufacturing issues is ETC-216, an injected compound to clear plaque from arteries; it could enter large scale trials within a year, Pfizer said."There are several other drugs in the pipeline for various maladies:Six Pfizer Drugs To Watch Forbes.com Langreth 11.30.06, 4:00 PM ET

Joe wrote:

Pfizer hold the patent to ECT 216 a drug that is already proven to

reverse arterial blockages and cure most heart disease but they have

been withholding it from the FDA trials.

Read this! It is all about the money!!

http://www.drugdevelopment-technology.com/projects/etc/

Joe

Posted

Pfizer has had ect 216 since the mid 1990's. Interestingly, I do not

believe it used to be an injectionable drug. Pfizer could push this

drug through now but it would virtually cure heart disease thus cutting

deeply into their profits. They will delay as long as possible.

Joe

Fran wrote:

>

> Pfizer may have stopped trials on torcetrapib combo, but...

>

> " Pfizer is trying to convince Wall Street that it has a robust

> pipeline, following a series of pipeline setbacks in recent years.

> Among other problems, Pfizer pulled out of an effort to develop a

> sleeping pill called Indiplon after it ran into problems at the FDA,

> and just this week it discontinued a schizophrenia drug pact.

> Meanwhile, the company said that the antibiotic Dalbavancin, which has

> been delayed at the FDA, should be approved in the first half of 2007.

>

> Another drug that has been delayed because of manufacturing issues is

> ETC-216, an injected compound to clear plaque from arteries; it could

> enter large scale trials within a year, Pfizer said. "

>

> There are several other drugs in the pipeline for various maladies:

> *Si x Pfizer Drugs To Watch

>

<http://www.forbes.com/2006/11/30/pfizer-drug-pipeline-biz-cz_rl_1130drugs_print\

..html> *

> Forbes.com

> Langreth 11.30.06, 4:00 PM ET

>

> Joe wrote:

> Pfizer hold the patent to ECT 216 a drug that is already proven to

> reverse arterial blockages and cure most heart disease but they have

> been withholding it from the FDA trials.

> Read this! It is all about the money!!

> http://www.drugdeve lopment-technolo gy.com/projects/ etc/

> <http://www.drugdevelopment-technology.com/projects/etc/>

> Joe

>

>

>

>

Pfizer has had ect 216 since the mid 1990's. Interestingly, I do not

believe it used to be an injectionable drug. Pfizer could push this

drug through now but it would virtually cure heart disease thus cutting

deeply into their profits. They will delay as long as possible.

Joe

Posted

Joe -- the source you listed in your original posting on this subject

said it was an intravenous drug

Marty

> > Pfizer hold the patent to ECT 216 a drug that is already proven to

> > reverse arterial blockages and cure most heart disease but they have

> > been withholding it from the FDA trials.

> > Read this! It is all about the money!!

> > http://www.drugdeve lopment-technolo gy.com/projects/ etc/

> > <http://www.drugdevelopment-technology.com/projects/etc/>

> > Joe

> >

> >

> >

> >

> Pfizer has had ect 216 since the mid 1990's. Interestingly, I do not

> believe it used to be an injectionable drug. Pfizer could push this

> drug through now but it would virtually cure heart disease thus cutting

> deeply into their profits. They will delay as long as possible.

>

> Joe

>

Posted

,

Yes they did. When I researched this drug a couple of years ago I

understood it to be in pill form. The drug itself is a duplicate of a

type of gene found in some people in Itally who eat lots of pasta etc

and yet have pristine arteries. I could be wrong about the drug

originally being in pill form.

Joe

Carbone wrote:

>

> Joe -- the source you listed in your original posting on this subject

> said it was an intravenous drug

>

> Marty

>

>

> > > Pfizer hold the patent to ECT 216 a drug that is already proven to

> > > reverse arterial blockages and cure most heart disease but they have

> > > been withholding it from the FDA trials.

> > > Read this! It is all about the money!!

> > > http://www.drugdeve lopment-technolo gy.com/projects/ etc/

> > > <http://www.drugdeve lopment-technolo gy.com/projects/ etc/

> <http://www.drugdevelopment-technology.com/projects/etc/>>

> > > Joe

> > >

> > >

> > >

> > >

> > Pfizer has had ect 216 since the mid 1990's. Interestingly, I do not

> > believe it used to be an injectionable drug. Pfizer could push this

> > drug through now but it would virtually cure heart disease thus cutting

> > deeply into their profits. They will delay as long as possible.

> >

> > Joe

> >

>

>

,

Yes they did. When I researched this drug a couple of years ago I

understood it to be in pill form. The drug itself is a duplicate of a

type of gene found in some people in Itally who eat lots of pasta etc

and yet have pristine arteries. I could be wrong about the drug

originally being in pill form.

Joe

Posted

Joe,

As far as I have read nothing is available in pill form for this type

of product. It is given to test subjects in the form of 5 weekly

transfusions at this time. Heres some more...

http://www.usatoday.com/news/health/2006-01-08-heart-disease-cover_x.htm

The apoA-1 Milano story illustrates how a chance observation can

uncover a medical mystery and trigger an explosion of medical research.

There's nothing dramatic about Chapter One: Three decades ago an

ailing 49-year-old man visited a doctor in the northern Italian

village of Limone sul Garda.

The doctor found that the villager's HDL of 7 was dangerously low,

well below the normal level of 40. His triglycerides, other blood fats

linked to heart disease, were 319, more than twice the norm. Despite

these ominous signs, his arteries were clear, says Cedars Sinai

Hospital's Prediman Shah.

Puzzled by the result, the doctor sent the villager to a specialist,

Cesare Sirtori, in Milan. The case so intrigued Sirtori that he

screened all 1,100 residents of Limone sul Garda to see whether he

could find others with similar blood profiles. He found 40 people, all

of whom could be traced to common ancestors born in the late 1700s.

Their HDL averaged less than 20, half of normal for men and women.

The doctor sent blood samples to the Gladstone Institute of

Cardiovascular Disease at the University of California-San Francisco.

Researchers there found that the villagers had a mutation in HDL's

biggest protein, apoA-1. They dubbed the mutant version apoA-1 Milano.

Shah infused synthetic apoA-1 Milano into rats and rabbits that were

fed fatty food. Plaques in their arteries shrank. During a celebratory

dinner in Milan, several researchers decided to form a company called

Espirion to develop apoA-1 Milano for use in patients. Newton,

the company's new CEO and a developer of Lipitor, recruited the

Cleveland Clinic's Nissen to test it.

Nissen was picked because he had helped develop IVUS, which allows

doctors to peek inside coronary arteries and measure the blockages

they find.

" I started out by telling my lab team it wouldn't work, " Nissen says.

" How do you take a disease that has taken decades to develop and

reverse it? "

Using IVUS in 47 heart patients, he found that just one infusion of

apoA-1 Milano a week for five weeks shrank their artery-blocking

plaques by more than 4%, the first time that any treatment has melted

plaque away. " I just about fell off my chair, " Nissen says.

The study turned apoA-1 Milano into a billion-dollar molecule. Just

days after Nissen published the results in the Journal of the American

Medical Association in 2003, the drug goliath Pfizer bought Espirion

Therapeutics and apoA-1 for $1.3 billion.

> > > > Pfizer hold the patent to ECT 216 a drug that is already proven to

> > > > reverse arterial blockages and cure most heart disease but

they have

> > > > been withholding it from the FDA trials.

> > > > Read this! It is all about the money!!

> > > > http://www.drugdeve lopment-technolo gy.com/projects/ etc/

> > > > <http://www.drugdeve lopment-technolo gy.com/projects/ etc/

> > <http://www.drugdevelopment-technology.com/projects/etc/>>

> > > > Joe

> > > >

> > > >

> > > >

> > > >

> > > Pfizer has had ect 216 since the mid 1990's. Interestingly, I do not

> > > believe it used to be an injectionable drug. Pfizer could push this

> > > drug through now but it would virtually cure heart disease thus

cutting

> > > deeply into their profits. They will delay as long as possible.

> > >

> > > Joe

> > >

> >

> >

>

> ,

> Yes they did. When I researched this drug a couple of years ago I

> understood it to be in pill form. The drug itself is a duplicate of a

> type of gene found in some people in Itally who eat lots of pasta etc

> and yet have pristine arteries. I could be wrong about the drug

> originally being in pill form.

>

> Joe

>

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