Re: Re: Valtrex opening methylation pathway? Can't get enough MB12? -HELP!

[Guest guest]

Gayatri I had a look at the cycles. Looks like chinese puzzle. What metal would trigger deficiency of folic acid. RehanaGayatri Rampal <gayatri_rampal@...> wrote: Anne:Given the prevalent thought that viruses and metals are intertwined (for lack of a better word) and that the presence of metals (and viruses) inhibit the enzymes that run the methylation cycles, it really is not surprising at all. In fact my personal opinion is that the sulphation

pathways are affected by viruses as well. Have you seen any red ears whilst on Valtrex (running out of the PST enzyme). What I love about Yasko and her diagrams is that I have actually begun to understand this stuff!!http://www.holistichealth.com/genetics.htmSee the 6th diagram with the metals.Gayatri>> Hi Everyone,> > My son has been on Valtrex for about 4 months. I don't think it > will be the thing that ultimately recovers my son, but it has been a > very good intervention for us.> > Here is my question: My son was never able to tolerate any MB12 > (whether by injection or spray) until fairly recently (and he got > little if any benefit from oral

MB12). For the last few weeks, my > son has been showing signs of B12 deficiency (red sides and tip of > tongue. In fact, it had gotten quite bad. I am thinking that > perhaps the Valtrex helped open up a methylation pathway....?> > For the umpteenth time, I tried the MB12/Folinic nasal spray on him, > and lo and behold, he is tolerating it fine. I have been giving him > one spray each morning for the last week, without problems. The > tongue has improved some, but the signs of deficiency are still > there. If I am right that this is a B12 deficiency sign, it is > almost like he needs lots of B12 now. Is that possible? How much > can I give him? Does anyone else know what these signs could point > to? Any other deficiency I may be missing? Any co-factors to help > bring the B12 levels up? > > The only thing that annoys me about the Valtrex is that it has

> changed things so much I can't figure out what the heck to do!> > Thanks in advance.> > Anne>

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Gayatri I had a look at the cycles. Looks like chinese puzzle. What metal would trigger deficiency of folic acid. RehanaGayatri Rampal <gayatri_rampal@...> wrote: Anne:Given the prevalent thought that viruses and metals are intertwined (for lack of a better word) and that the presence of metals (and viruses) inhibit the enzymes that run the methylation cycles, it really is not surprising at all. In fact my personal opinion is that the sulphation

pathways are affected by viruses as well. Have you seen any red ears whilst on Valtrex (running out of the PST enzyme). What I love about Yasko and her diagrams is that I have actually begun to understand this stuff!!http://www.holistichealth.com/genetics.htmSee the 6th diagram with the metals.Gayatri>> Hi Everyone,> > My son has been on Valtrex for about 4 months. I don't think it > will be the thing that ultimately recovers my son, but it has been a > very good intervention for us.> > Here is my question: My son was never able to tolerate any MB12 > (whether by injection or spray) until fairly recently (and he got > little if any benefit from oral

MB12). For the last few weeks, my > son has been showing signs of B12 deficiency (red sides and tip of > tongue. In fact, it had gotten quite bad. I am thinking that > perhaps the Valtrex helped open up a methylation pathway....?> > For the umpteenth time, I tried the MB12/Folinic nasal spray on him, > and lo and behold, he is tolerating it fine. I have been giving him > one spray each morning for the last week, without problems. The > tongue has improved some, but the signs of deficiency are still > there. If I am right that this is a B12 deficiency sign, it is > almost like he needs lots of B12 now. Is that possible? How much > can I give him? Does anyone else know what these signs could point > to? Any other deficiency I may be missing? Any co-factors to help > bring the B12 levels up? > > The only thing that annoys me about the Valtrex is that it has

> changed things so much I can't figure out what the heck to do!> > Thanks in advance.> > Anne>

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Which metal causes folic acid deficiency RehanaGayatri Rampal <gayatri_rampal@...> wrote: Anne I should have added these are PDF files. To see them don't forget to use the "rotate clockwise" feature in the toolbar on the top to the right, else you run the risk of getting a crick in the neck.Gayatri--- .

All new "The new Interface is stunning in its simplicity and ease of use." - PC Magazine

[Guest guest]

Which metal causes folic acid deficiency RehanaGayatri Rampal <gayatri_rampal@...> wrote: Anne I should have added these are PDF files. To see them don't forget to use the "rotate clockwise" feature in the toolbar on the top to the right, else you run the risk of getting a crick in the neck.Gayatri--- .

All new "The new Interface is stunning in its simplicity and ease of use." - PC Magazine

[Guest guest]

Hello Gayatri, I've been looking over Amy Yasko's site and her diagrams. I am only now beginning to understand them. Basically, the diagrams show a complicated set of intertwined events (pathways) which are being screwed up because of the metals -- right? The metal interference is causing all the symptoms and thus the autism -- is that correct? So what is Amy Yasko's protocal to fix this? Is it chelation? Valtrex? something else? Also, I notice the diagrams do not deal with the testosterone factor. Do you know if Dr. Yasko considers high testosterone when treating her patients? You seem to understand her charts and I hope you don't mind my many questions. Thank you. Gayatri Rampal <gayatri_rampal@...> wrote: Anne:Given the prevalent thought that viruses and metals are intertwined (for lack of a better word) and that the presence of metals (and viruses) inhibit the enzymes that run the methylation cycles, it really is not surprising at all. In fact my personal opinion is that the sulphation pathways are affected by viruses as well. Have you seen any red ears whilst on Valtrex (running out of the PST enzyme). What I love about Yasko and her

diagrams is that I have actually begun to understand this stuff!!http://www.holistichealth.com/genetics.htmSee the 6th diagram with the metals.Gayatri>> Hi Everyone,> > My son has been on Valtrex for about 4 months. I don't think it > will be the thing that ultimately recovers my son, but it has been a > very good intervention for us.> > Here is my question: My son was never able to tolerate any MB12 > (whether by injection or spray) until fairly recently (and he got > little if any benefit from oral MB12). For the last few weeks, my > son has been showing signs of B12 deficiency (red sides and tip of > tongue. In fact, it had gotten quite bad. I

am thinking that > perhaps the Valtrex helped open up a methylation pathway....?> > For the umpteenth time, I tried the MB12/Folinic nasal spray on him, > and lo and behold, he is tolerating it fine. I have been giving him > one spray each morning for the last week, without problems. The > tongue has improved some, but the signs of deficiency are still > there. If I am right that this is a B12 deficiency sign, it is > almost like he needs lots of B12 now. Is that possible? How much > can I give him? Does anyone else know what these signs could point > to? Any other deficiency I may be missing? Any co-factors to help > bring the B12 levels up? > > The only thing that annoys me about the Valtrex is that it has > changed things so much I can't figure out what the heck to do!> > Thanks in advance.> >

Anne> __________________________________________________

[Guest guest]

Hello Gayatri, I've been looking over Amy Yasko's site and her diagrams. I am only now beginning to understand them. Basically, the diagrams show a complicated set of intertwined events (pathways) which are being screwed up because of the metals -- right? The metal interference is causing all the symptoms and thus the autism -- is that correct? So what is Amy Yasko's protocal to fix this? Is it chelation? Valtrex? something else? Also, I notice the diagrams do not deal with the testosterone factor. Do you know if Dr. Yasko considers high testosterone when treating her patients? You seem to understand her charts and I hope you don't mind my many questions. Thank you. Gayatri Rampal <gayatri_rampal@...> wrote: Anne:Given the prevalent thought that viruses and metals are intertwined (for lack of a better word) and that the presence of metals (and viruses) inhibit the enzymes that run the methylation cycles, it really is not surprising at all. In fact my personal opinion is that the sulphation pathways are affected by viruses as well. Have you seen any red ears whilst on Valtrex (running out of the PST enzyme). What I love about Yasko and her

diagrams is that I have actually begun to understand this stuff!!http://www.holistichealth.com/genetics.htmSee the 6th diagram with the metals.Gayatri>> Hi Everyone,> > My son has been on Valtrex for about 4 months. I don't think it > will be the thing that ultimately recovers my son, but it has been a > very good intervention for us.> > Here is my question: My son was never able to tolerate any MB12 > (whether by injection or spray) until fairly recently (and he got > little if any benefit from oral MB12). For the last few weeks, my > son has been showing signs of B12 deficiency (red sides and tip of > tongue. In fact, it had gotten quite bad. I

am thinking that > perhaps the Valtrex helped open up a methylation pathway....?> > For the umpteenth time, I tried the MB12/Folinic nasal spray on him, > and lo and behold, he is tolerating it fine. I have been giving him > one spray each morning for the last week, without problems. The > tongue has improved some, but the signs of deficiency are still > there. If I am right that this is a B12 deficiency sign, it is > almost like he needs lots of B12 now. Is that possible? How much > can I give him? Does anyone else know what these signs could point > to? Any other deficiency I may be missing? Any co-factors to help > bring the B12 levels up? > > The only thing that annoys me about the Valtrex is that it has > changed things so much I can't figure out what the heck to do!> > Thanks in advance.> >

Anne> __________________________________________________

[Guest guest]

I’ve

seen the red ears and wondered what exactly was going on with Drew. I thought

maybe he was reacting to a food, but he hasn’t had anything different in

his diet for over 2 years. That is very interesting!

Missy Nadeau

Re: Valtrex

opening methylation pathway? Can't get enough MB12? -HELP!

Anne I should have added

these are PDF files. To see them don't

forget to use the " rotate clockwise " feature in the toolbar on the

top to the right, else you run the risk of getting a crick in the

neck.

Gayatri

> >

> > Hi Everyone,

> >

> > My son has been on Valtrex for about 4 months. I don't think it

> > will be the thing that ultimately recovers my son, but it has

been

> a

> > very good intervention for us.

> >

> > Here is my question: My son was never able to tolerate any MB12

> > (whether by injection or spray) until fairly recently (and he

got

> > little if any benefit from oral MB12). For the last few weeks,

my

> > son has been showing signs of B12 deficiency (red sides and tip

of

> > tongue. In fact, it had gotten quite bad. I am thinking that

> > perhaps the Valtrex helped open up a methylation pathway....?

> >

> > For the umpteenth time, I tried the MB12/Folinic nasal spray on

> him,

> > and lo and behold, he is tolerating it fine. I have been giving

> him

> > one spray each morning for the last week, without problems. The

> > tongue has improved some, but the signs of deficiency are still

> > there. If I am right that this is a B12 deficiency sign, it is

> > almost like he needs lots of B12 now. Is that possible? How

much

> > can I give him? Does anyone else know what these signs could

> point

> > to? Any other deficiency I may be missing? Any co-factors to

> help

> > bring the B12 levels up?

> >

> > The only thing that annoys me about the Valtrex is that it has

> > changed things so much I can't figure out what the heck to do!

> >

> > Thanks in advance.

> >

> > Anne

> >

>

[Guest guest]

I’ve

seen the red ears and wondered what exactly was going on with Drew. I thought

maybe he was reacting to a food, but he hasn’t had anything different in

his diet for over 2 years. That is very interesting!

Missy Nadeau

Re: Valtrex

opening methylation pathway? Can't get enough MB12? -HELP!

Anne I should have added

these are PDF files. To see them don't

forget to use the " rotate clockwise " feature in the toolbar on the

top to the right, else you run the risk of getting a crick in the

neck.

Gayatri

> >

> > Hi Everyone,

> >

> > My son has been on Valtrex for about 4 months. I don't think it

> > will be the thing that ultimately recovers my son, but it has

been

> a

> > very good intervention for us.

> >

> > Here is my question: My son was never able to tolerate any MB12

> > (whether by injection or spray) until fairly recently (and he

got

> > little if any benefit from oral MB12). For the last few weeks,

my

> > son has been showing signs of B12 deficiency (red sides and tip

of

> > tongue. In fact, it had gotten quite bad. I am thinking that

> > perhaps the Valtrex helped open up a methylation pathway....?

> >

> > For the umpteenth time, I tried the MB12/Folinic nasal spray on

> him,

> > and lo and behold, he is tolerating it fine. I have been giving

> him

> > one spray each morning for the last week, without problems. The

> > tongue has improved some, but the signs of deficiency are still

> > there. If I am right that this is a B12 deficiency sign, it is

> > almost like he needs lots of B12 now. Is that possible? How

much

> > can I give him? Does anyone else know what these signs could

> point

> > to? Any other deficiency I may be missing? Any co-factors to

> help

> > bring the B12 levels up?

> >

> > The only thing that annoys me about the Valtrex is that it has

> > changed things so much I can't figure out what the heck to do!

> >

> > Thanks in advance.

> >

> > Anne

> >

>

[Guest guest]

Good Grief-if you know all this and are a novice-what does that say about me. Wow!Gayatri Rampal <gayatri_rampal@...> wrote: Rehana I am a novice at this and so will attempt to explain to the best of my ability. In the diagram 5 Methyl THF is the form of folate that the body uses. If you have a mutation in the MTHFR (C677T) which is the circle in the middle, then you cannot easily convert folate/folinic to 5MTHF and so you will need something like Folapro (from Metagenics) to supply some form of folic acid to the body. Yasko cautions

that you do her Step 1 supplement support prior to adding in Folapro.The MTHFR has another mutation the A1298C. As a Yasko mom explained it to me here goes:"The MTHFr A1298C is a problem but there are ways around it. This enzyme influences the reverse reaction of the folate cycle ( I think I said that right). On your diagram where the middle circle is you will see a rectangle that represents MTHFR, this is our enzyme. Folic acid will have trouble converting to 5 Methyl TetrahydroFolate that's where our Folapro will be useful AFTER step one supplements. It is also responsible for the reverse reaction in making BH4 on the circle to the left (see how the arrows go both ways? So the thought is that BH4 goes around the circle, 2 parts go to the Urea Cycle to clean out the trash and 2 parts go back around to the MTHFr enzyme to make more BH4. The MTHFr enzyme borrows from SAMe to make more BH4, but not in this

case. It isn't likely because of the ++ that the MTHFr A1298C is able to borrow from SAMe. SO we have an enzyme MTHFr A1298C (with added burden of metal, bacteria blocking the enzyme) that has a double block. So instead of have the 4 parts of BH4 at the top of the circle lets imagine that we only have 3 parts. Lets say for illustrative purposes that 1 1/2 parts go to the Urea Cycle which is not juctioning at top speed because we already have the NOS+- there, and 1 1/2 parts go back into our original cycle. You need BH4 for all kinds of things, you also need it for serotonin/dopamine synthesis. You need serotonin/dopamine synthesis for language. I don't know if your son is verbal or not. It may be that the body is using the BH4 for language and it may be that it is using it for the Urea Cycle or a number of other things, but this is what I understand and can remember at the moment about it. It is not necessary to have

the pure or pharma BH4, parents are getting detox from the BIO THYRO which contains BH4. I've used it myself and plan to in the next couple of weeks. Lowering the burden of lipid, sulphur supplements will also free up some room for BH4 to be processed naturally Royal Jelly is also a naural source of BH4.""The MTR and MTRR is a severe lack of of Vitamin B12 production. The multi Vitamin from HHC will have small amount of SAMe and Methionine to assist with other parts of the cycle for these mutaitons, outside of that Hydroxy and cyano B12 would be recommened."To your question about which metal is blocking folic acid, I don't know - the answer as you can probably tell lies in mutations and viruses/bacteria and metals. If you go and read at autismanswer.com you can find out a lot of theory but it probably won't make individual sense if you don't have your genetic mutations on hand. There is only one panel

available now, costs $750, and it at www.holistichealth.com. If you want a GAR (Genetic Analysis Review) that will be an additional $575. The parents there are very helpful if you have questions. You can go to the Basic Forum and read to get a sense of the protocol. Also the same website will let you buy the suplements mentioned above - HHC (a multivitamin) or Bio-thyro - should you want to.HTHGayatri> Anne I should have added these are PDF files. To see them don't > forget to use the "rotate clockwise" feature in the toolbar on the > top to the right, else you run the risk of getting a crick

in the > neck.> > Gayatri> > ---> > > We Made Changes> Your email is all new.> Learn More> > > > Share Feedback> > > Recent Activity> > 54> New Members> > 1> New Photos> > Visit Your Group >

[Guest guest]

Good Grief-if you know all this and are a novice-what does that say about me. Wow!Gayatri Rampal <gayatri_rampal@...> wrote: Rehana I am a novice at this and so will attempt to explain to the best of my ability. In the diagram 5 Methyl THF is the form of folate that the body uses. If you have a mutation in the MTHFR (C677T) which is the circle in the middle, then you cannot easily convert folate/folinic to 5MTHF and so you will need something like Folapro (from Metagenics) to supply some form of folic acid to the body. Yasko cautions

that you do her Step 1 supplement support prior to adding in Folapro.The MTHFR has another mutation the A1298C. As a Yasko mom explained it to me here goes:"The MTHFr A1298C is a problem but there are ways around it. This enzyme influences the reverse reaction of the folate cycle ( I think I said that right). On your diagram where the middle circle is you will see a rectangle that represents MTHFR, this is our enzyme. Folic acid will have trouble converting to 5 Methyl TetrahydroFolate that's where our Folapro will be useful AFTER step one supplements. It is also responsible for the reverse reaction in making BH4 on the circle to the left (see how the arrows go both ways? So the thought is that BH4 goes around the circle, 2 parts go to the Urea Cycle to clean out the trash and 2 parts go back around to the MTHFr enzyme to make more BH4. The MTHFr enzyme borrows from SAMe to make more BH4, but not in this

case. It isn't likely because of the ++ that the MTHFr A1298C is able to borrow from SAMe. SO we have an enzyme MTHFr A1298C (with added burden of metal, bacteria blocking the enzyme) that has a double block. So instead of have the 4 parts of BH4 at the top of the circle lets imagine that we only have 3 parts. Lets say for illustrative purposes that 1 1/2 parts go to the Urea Cycle which is not juctioning at top speed because we already have the NOS+- there, and 1 1/2 parts go back into our original cycle. You need BH4 for all kinds of things, you also need it for serotonin/dopamine synthesis. You need serotonin/dopamine synthesis for language. I don't know if your son is verbal or not. It may be that the body is using the BH4 for language and it may be that it is using it for the Urea Cycle or a number of other things, but this is what I understand and can remember at the moment about it. It is not necessary to have

the pure or pharma BH4, parents are getting detox from the BIO THYRO which contains BH4. I've used it myself and plan to in the next couple of weeks. Lowering the burden of lipid, sulphur supplements will also free up some room for BH4 to be processed naturally Royal Jelly is also a naural source of BH4.""The MTR and MTRR is a severe lack of of Vitamin B12 production. The multi Vitamin from HHC will have small amount of SAMe and Methionine to assist with other parts of the cycle for these mutaitons, outside of that Hydroxy and cyano B12 would be recommened."To your question about which metal is blocking folic acid, I don't know - the answer as you can probably tell lies in mutations and viruses/bacteria and metals. If you go and read at autismanswer.com you can find out a lot of theory but it probably won't make individual sense if you don't have your genetic mutations on hand. There is only one panel

available now, costs $750, and it at www.holistichealth.com. If you want a GAR (Genetic Analysis Review) that will be an additional $575. The parents there are very helpful if you have questions. You can go to the Basic Forum and read to get a sense of the protocol. Also the same website will let you buy the suplements mentioned above - HHC (a multivitamin) or Bio-thyro - should you want to.HTHGayatri> Anne I should have added these are PDF files. To see them don't > forget to use the "rotate clockwise" feature in the toolbar on the > top to the right, else you run the risk of getting a crick

in the > neck.> > Gayatri> > ---> > > We Made Changes> Your email is all new.> Learn More> > > > Share Feedback> > > Recent Activity> > 54> New Members> > 1> New Photos> > Visit Your Group >

[Guest guest]

Gayatri Very pleased that you have replied to my question I will have to read this 10 times to understand the intricacies of this. I will come back with more questions if you do not mind. Many thanks and you must be a genuis to understand these complex flowcharts. Warm wishes Rehana Maurine Meleck <maurine_meleck@...> wrote: Good Grief-if you know all this and are a novice-what does that say about

me. Wow!Gayatri Rampal <gayatri_rampal@...> wrote: Rehana I am a novice at this and so will attempt to explain to the best of my ability. In the diagram 5 Methyl THF is the form of folate that the body uses. If you have a mutation in the MTHFR (C677T) which is the circle in the middle, then you cannot easily convert folate/folinic to 5MTHF and so you will need something like Folapro (from Metagenics) to supply some form of folic acid to the body. Yasko cautions that you do her Step 1 supplement support prior to adding in Folapro.The MTHFR has another mutation the A1298C. As a Yasko mom explained it to me here goes:"The MTHFr A1298C is a problem but there are ways around it. This enzyme influences the reverse reaction of the folate cycle ( I think I said that right). On your diagram

where the middle circle is you will see a rectangle that represents MTHFR, this is our enzyme. Folic acid will have trouble converting to 5 Methyl TetrahydroFolate that's where our Folapro will be useful AFTER step one supplements. It is also responsible for the reverse reaction in making BH4 on the circle to the left (see how the arrows go both ways? So the thought is that BH4 goes around the circle, 2 parts go to the Urea Cycle to clean out the trash and 2 parts go back around to the MTHFr enzyme to make more BH4. The MTHFr enzyme borrows from SAMe to make more BH4, but not in this case. It isn't likely because of the ++ that the MTHFr A1298C is able to borrow from SAMe. SO we have an enzyme MTHFr A1298C (with added burden of metal, bacteria blocking the enzyme) that has a double block. So instead of have the 4 parts of BH4 at the top of the circle lets imagine that we only have 3 parts. Lets say for illustrative

purposes that 1 1/2 parts go to the Urea Cycle which is not juctioning at top speed because we already have the NOS+- there, and 1 1/2 parts go back into our original cycle. You need BH4 for all kinds of things, you also need it for serotonin/dopamine synthesis. You need serotonin/dopamine synthesis for language. I don't know if your son is verbal or not. It may be that the body is using the BH4 for language and it may be that it is using it for the Urea Cycle or a number of other things, but this is what I understand and can remember at the moment about it. It is not necessary to have the pure or pharma BH4, parents are getting detox from the BIO THYRO which contains BH4. I've used it myself and plan to in the next couple of weeks. Lowering the burden of lipid, sulphur supplements will also free up some room for BH4 to be processed naturally Royal Jelly is also a naural source of BH4.""The MTR and MTRR is a

severe lack of of Vitamin B12 production. The multi Vitamin from HHC will have small amount of SAMe and Methionine to assist with other parts of the cycle for these mutaitons, outside of that Hydroxy and cyano B12 would be recommened."To your question about which metal is blocking folic acid, I don't know - the answer as you can probably tell lies in mutations and viruses/bacteria and metals. If you go and read at autismanswer.com you can find out a lot of theory but it probably won't make individual sense if you don't have your genetic mutations on hand. There is only one panel available now, costs $750, and it at www.holistichealth.com. If you want a GAR (Genetic Analysis Review) that will be an additional $575. The parents there are very helpful if you have questions. You can go to the Basic Forum and read to get a sense of the protocol. Also the same website will let you buy the suplements

mentioned above - HHC (a multivitamin) or Bio-thyro - should you want to.HTHGayatri> Anne I should have added these are PDF files. To see them don't > forget to use the "rotate clockwise" feature in the toolbar on the > top to the right, else you run the risk of getting a crick in the > neck.> > Gayatri> > ---> > > We Made Changes> Your email is all new.> Learn More> > > > Share Feedback> > > Recent Activity> > 54> New Members> > 1> New

Photos> > Visit Your Group >

[Guest guest]

Gayatri Very pleased that you have replied to my question I will have to read this 10 times to understand the intricacies of this. I will come back with more questions if you do not mind. Many thanks and you must be a genuis to understand these complex flowcharts. Warm wishes Rehana Maurine Meleck <maurine_meleck@...> wrote: Good Grief-if you know all this and are a novice-what does that say about

me. Wow!Gayatri Rampal <gayatri_rampal@...> wrote: Rehana I am a novice at this and so will attempt to explain to the best of my ability. In the diagram 5 Methyl THF is the form of folate that the body uses. If you have a mutation in the MTHFR (C677T) which is the circle in the middle, then you cannot easily convert folate/folinic to 5MTHF and so you will need something like Folapro (from Metagenics) to supply some form of folic acid to the body. Yasko cautions that you do her Step 1 supplement support prior to adding in Folapro.The MTHFR has another mutation the A1298C. As a Yasko mom explained it to me here goes:"The MTHFr A1298C is a problem but there are ways around it. This enzyme influences the reverse reaction of the folate cycle ( I think I said that right). On your diagram

where the middle circle is you will see a rectangle that represents MTHFR, this is our enzyme. Folic acid will have trouble converting to 5 Methyl TetrahydroFolate that's where our Folapro will be useful AFTER step one supplements. It is also responsible for the reverse reaction in making BH4 on the circle to the left (see how the arrows go both ways? So the thought is that BH4 goes around the circle, 2 parts go to the Urea Cycle to clean out the trash and 2 parts go back around to the MTHFr enzyme to make more BH4. The MTHFr enzyme borrows from SAMe to make more BH4, but not in this case. It isn't likely because of the ++ that the MTHFr A1298C is able to borrow from SAMe. SO we have an enzyme MTHFr A1298C (with added burden of metal, bacteria blocking the enzyme) that has a double block. So instead of have the 4 parts of BH4 at the top of the circle lets imagine that we only have 3 parts. Lets say for illustrative

purposes that 1 1/2 parts go to the Urea Cycle which is not juctioning at top speed because we already have the NOS+- there, and 1 1/2 parts go back into our original cycle. You need BH4 for all kinds of things, you also need it for serotonin/dopamine synthesis. You need serotonin/dopamine synthesis for language. I don't know if your son is verbal or not. It may be that the body is using the BH4 for language and it may be that it is using it for the Urea Cycle or a number of other things, but this is what I understand and can remember at the moment about it. It is not necessary to have the pure or pharma BH4, parents are getting detox from the BIO THYRO which contains BH4. I've used it myself and plan to in the next couple of weeks. Lowering the burden of lipid, sulphur supplements will also free up some room for BH4 to be processed naturally Royal Jelly is also a naural source of BH4.""The MTR and MTRR is a

severe lack of of Vitamin B12 production. The multi Vitamin from HHC will have small amount of SAMe and Methionine to assist with other parts of the cycle for these mutaitons, outside of that Hydroxy and cyano B12 would be recommened."To your question about which metal is blocking folic acid, I don't know - the answer as you can probably tell lies in mutations and viruses/bacteria and metals. If you go and read at autismanswer.com you can find out a lot of theory but it probably won't make individual sense if you don't have your genetic mutations on hand. There is only one panel available now, costs $750, and it at www.holistichealth.com. If you want a GAR (Genetic Analysis Review) that will be an additional $575. The parents there are very helpful if you have questions. You can go to the Basic Forum and read to get a sense of the protocol. Also the same website will let you buy the suplements

mentioned above - HHC (a multivitamin) or Bio-thyro - should you want to.HTHGayatri> Anne I should have added these are PDF files. To see them don't > forget to use the "rotate clockwise" feature in the toolbar on the > top to the right, else you run the risk of getting a crick in the > neck.> > Gayatri> > ---> > > We Made Changes> Your email is all new.> Learn More> > > > Share Feedback> > > Recent Activity> > 54> New Members> > 1> New

Photos> > Visit Your Group >

[Guest guest]

My little guy would qualify as a COMT+++ kid and shows a lot of viral

issues. He also does not have the CBS 699 up regulation, which was

suppose to the " trump card " to autism years ago (a must have). With

the polluted environment and vaccination schedule, I'm not quite sure

what the " magic bullet " in avoiding an autism diagnoses anymore.

I'm afraid to think that the bar is going lower and lower the more we

do to our environment.

---- Original Message ----

From: gayatri_rampal@...

mb12 valtrex

Subject: Re: Valtrex opening methylation pathway?

Can't get enough MB12? -HELP!

Date: Wed, 07 Jun 2006 04:56:12 -0000

> I should qualify that my son has had severe sulphur issues

>in the past, even whilst his measles titres were mildly to

>moderately elevated, not superhigh. Maybe the sulphur problem is

>what makes his health issues more severe, he is also a seizures kid.

>What makes it even more strange is that he is a COMT++ kid and

>should be having a lower metal and viral load, but I think

>everything is connected and maybe the sulphur problem colors the

>picture.

>

>Gayatri

>

>

>

>

>> >

>> > Anne:

>> >

>> > Given the prevalent thought that viruses and metals are

>intertwined

>> > (for lack of a better word) and that the presence of metals (and

>> > viruses) inhibit the enzymes that run the methylation cycles, it

>> > really is not surprising at all. In fact my personal opinion is

>> that

>> > the sulphation pathways are affected by viruses as well. Have

>you

>> > seen any red ears whilst on Valtrex (running out of the PST

>> enzyme).

>> > What I love about Yasko and her diagrams is that I have actually

>> > begun to understand this stuff!!

>> >

>> > http://www.holistichealth.com/genetics.htm

>> >

>> > See the 6th diagram with the metals.

>> >

>> > Gayatri

>>

>

>

>

>

[Guest guest]

My little guy would qualify as a COMT+++ kid and shows a lot of viral

issues. He also does not have the CBS 699 up regulation, which was

suppose to the " trump card " to autism years ago (a must have). With

the polluted environment and vaccination schedule, I'm not quite sure

what the " magic bullet " in avoiding an autism diagnoses anymore.

I'm afraid to think that the bar is going lower and lower the more we

do to our environment.

---- Original Message ----

From: gayatri_rampal@...

mb12 valtrex

Subject: Re: Valtrex opening methylation pathway?

Can't get enough MB12? -HELP!

Date: Wed, 07 Jun 2006 04:56:12 -0000

> I should qualify that my son has had severe sulphur issues

>in the past, even whilst his measles titres were mildly to

>moderately elevated, not superhigh. Maybe the sulphur problem is

>what makes his health issues more severe, he is also a seizures kid.

>What makes it even more strange is that he is a COMT++ kid and

>should be having a lower metal and viral load, but I think

>everything is connected and maybe the sulphur problem colors the

>picture.

>

>Gayatri

>

>

>

>

>> >

>> > Anne:

>> >

>> > Given the prevalent thought that viruses and metals are

>intertwined

>> > (for lack of a better word) and that the presence of metals (and

>> > viruses) inhibit the enzymes that run the methylation cycles, it

>> > really is not surprising at all. In fact my personal opinion is

>> that

>> > the sulphation pathways are affected by viruses as well. Have

>you

>> > seen any red ears whilst on Valtrex (running out of the PST

>> enzyme).

>> > What I love about Yasko and her diagrams is that I have actually

>> > begun to understand this stuff!!

>> >

>> > http://www.holistichealth.com/genetics.htm

>> >

>> > See the 6th diagram with the metals.

>> >

>> > Gayatri

>>

>

>

>

>

[Guest guest]

Hi Gayatri Correct me if I am wrong. I should get the multi vitamin first, 2nd give folapro which I have ordered already, 3rd do the detox and fourth try the Royal jelly. I will now go and search for the vitamins and detox on the website you mentioned. I Many thanks for sharing your knowledge with us Warm wishes Rehana Gayatri Rampal <gayatri_rampal@...> wrote: Rehana I am a novice at this and so will attempt to explain to the best of my ability. In the diagram 5 Methyl THF is the form of folate that the body uses. If you have a mutation in the MTHFR (C677T) which is the circle in the middle, then you cannot easily convert folate/folinic to 5MTHF and so you will need something like Folapro (from Metagenics) to supply some form of folic acid to the body. Yasko cautions that you do her Step 1 supplement support prior to adding in Folapro.The MTHFR has another mutation the A1298C. As a Yasko mom explained it to me here goes:"The MTHFr A1298C is a problem but there are ways around it. This enzyme influences the reverse reaction of the folate cycle ( I think I said that right). On your diagram where the middle circle is you will see a rectangle that represents MTHFR, this is our enzyme. Folic acid will have trouble converting to 5 Methyl

TetrahydroFolate that's where our Folapro will be useful AFTER step one supplements. It is also responsible for the reverse reaction in making BH4 on the circle to the left (see how the arrows go both ways? So the thought is that BH4 goes around the circle, 2 parts go to the Urea Cycle to clean out the trash and 2 parts go back around to the MTHFr enzyme to make more BH4. The MTHFr enzyme borrows from SAMe to make more BH4, but not in this case. It isn't likely because of the ++ that the MTHFr A1298C is able to borrow from SAMe. SO we have an enzyme MTHFr A1298C (with added burden of metal, bacteria blocking the enzyme) that has a double block. So instead of have the 4 parts of BH4 at the top of the circle lets imagine that we only have 3 parts. Lets say for illustrative purposes that 1 1/2 parts go to the Urea Cycle which is not juctioning at top speed because we already have the NOS+- there, and 1 1/2 parts go back

into our original cycle. You need BH4 for all kinds of things, you also need it for serotonin/dopamine synthesis. You need serotonin/dopamine synthesis for language. I don't know if your son is verbal or not. It may be that the body is using the BH4 for language and it may be that it is using it for the Urea Cycle or a number of other things, but this is what I understand and can remember at the moment about it. It is not necessary to have the pure or pharma BH4, parents are getting detox from the BIO THYRO which contains BH4. I've used it myself and plan to in the next couple of weeks. Lowering the burden of lipid, sulphur supplements will also free up some room for BH4 to be processed naturally Royal Jelly is also a naural source of BH4.""The MTR and MTRR is a severe lack of of Vitamin B12 production. The multi Vitamin from HHC will have small amount of SAMe and Methionine to assist with other parts of the cycle

for these mutaitons, outside of that Hydroxy and cyano B12 would be recommened."To your question about which metal is blocking folic acid, I don't know - the answer as you can probably tell lies in mutations and viruses/bacteria and metals. If you go and read at autismanswer.com you can find out a lot of theory but it probably won't make individual sense if you don't have your genetic mutations on hand. There is only one panel available now, costs $750, and it at www.holistichealth.com. If you want a GAR (Genetic Analysis Review) that will be an additional $575. The parents there are very helpful if you have questions. You can go to the Basic Forum and read to get a sense of the protocol. Also the same website will let you buy the suplements mentioned above - HHC (a multivitamin) or Bio-thyro - should you want to.HTHGayatri> Anne I should have added these are PDF files. To see them don't > forget to use the "rotate clockwise" feature in the toolbar on the > top to the right, else you run the risk of getting a crick in the > neck.> > Gayatri> > ---> > > We Made Changes> Your email is all new.> Learn More> > > > Share Feedback> > > Recent Activity> > 54> New Members> > 1> New Photos> > Visit Your Group >

[Guest guest]

Hi Gayatri Correct me if I am wrong. I should get the multi vitamin first, 2nd give folapro which I have ordered already, 3rd do the detox and fourth try the Royal jelly. I will now go and search for the vitamins and detox on the website you mentioned. I Many thanks for sharing your knowledge with us Warm wishes Rehana Gayatri Rampal <gayatri_rampal@...> wrote: Rehana I am a novice at this and so will attempt to explain to the best of my ability. In the diagram 5 Methyl THF is the form of folate that the body uses. If you have a mutation in the MTHFR (C677T) which is the circle in the middle, then you cannot easily convert folate/folinic to 5MTHF and so you will need something like Folapro (from Metagenics) to supply some form of folic acid to the body. Yasko cautions that you do her Step 1 supplement support prior to adding in Folapro.The MTHFR has another mutation the A1298C. As a Yasko mom explained it to me here goes:"The MTHFr A1298C is a problem but there are ways around it. This enzyme influences the reverse reaction of the folate cycle ( I think I said that right). On your diagram where the middle circle is you will see a rectangle that represents MTHFR, this is our enzyme. Folic acid will have trouble converting to 5 Methyl

TetrahydroFolate that's where our Folapro will be useful AFTER step one supplements. It is also responsible for the reverse reaction in making BH4 on the circle to the left (see how the arrows go both ways? So the thought is that BH4 goes around the circle, 2 parts go to the Urea Cycle to clean out the trash and 2 parts go back around to the MTHFr enzyme to make more BH4. The MTHFr enzyme borrows from SAMe to make more BH4, but not in this case. It isn't likely because of the ++ that the MTHFr A1298C is able to borrow from SAMe. SO we have an enzyme MTHFr A1298C (with added burden of metal, bacteria blocking the enzyme) that has a double block. So instead of have the 4 parts of BH4 at the top of the circle lets imagine that we only have 3 parts. Lets say for illustrative purposes that 1 1/2 parts go to the Urea Cycle which is not juctioning at top speed because we already have the NOS+- there, and 1 1/2 parts go back

into our original cycle. You need BH4 for all kinds of things, you also need it for serotonin/dopamine synthesis. You need serotonin/dopamine synthesis for language. I don't know if your son is verbal or not. It may be that the body is using the BH4 for language and it may be that it is using it for the Urea Cycle or a number of other things, but this is what I understand and can remember at the moment about it. It is not necessary to have the pure or pharma BH4, parents are getting detox from the BIO THYRO which contains BH4. I've used it myself and plan to in the next couple of weeks. Lowering the burden of lipid, sulphur supplements will also free up some room for BH4 to be processed naturally Royal Jelly is also a naural source of BH4.""The MTR and MTRR is a severe lack of of Vitamin B12 production. The multi Vitamin from HHC will have small amount of SAMe and Methionine to assist with other parts of the cycle

for these mutaitons, outside of that Hydroxy and cyano B12 would be recommened."To your question about which metal is blocking folic acid, I don't know - the answer as you can probably tell lies in mutations and viruses/bacteria and metals. If you go and read at autismanswer.com you can find out a lot of theory but it probably won't make individual sense if you don't have your genetic mutations on hand. There is only one panel available now, costs $750, and it at www.holistichealth.com. If you want a GAR (Genetic Analysis Review) that will be an additional $575. The parents there are very helpful if you have questions. You can go to the Basic Forum and read to get a sense of the protocol. Also the same website will let you buy the suplements mentioned above - HHC (a multivitamin) or Bio-thyro - should you want to.HTHGayatri> Anne I should have added these are PDF files. To see them don't > forget to use the "rotate clockwise" feature in the toolbar on the > top to the right, else you run the risk of getting a crick in the > neck.> > Gayatri> > ---> > > We Made Changes> Your email is all new.> Learn More> > > > Share Feedback> > > Recent Activity> > 54> New Members> > 1> New Photos> > Visit Your Group >