Re: Orapred - is refrigeration req'd????

August 15, 2006

Uh-oh, the pharmicist told me that refrigeration for Orapred was optional and I

don't refrig. mine - does this make it lose its effectiveness? I have an

unopened bottle that came from the pharmacy not refrigerated. Should I

refrigerate it after opening? We have noticed a change in our son's response to

the drug (e.g. needing more than one dose to eliminate a fever cycle) so I'm

worried that it may be due to something as simple as lack of refrigeration???

Any responses would be greatly appreciated!

Kathleen

Henry <heatherp_87@...> wrote:

Orapred now comes in 15mg/5ml. That is what we use.

Also, it is MUCH better tasting, as least to Audrey.

She doesn't fight with us half as much as she did with

the generic. It is worth the extra money. The only

down side is that it requires refrigeration.

Mother to (5) and Audrey (3 )

--- Fran Bulone <fbulone@...> wrote:

> Prednisone and Orapred ONLY comes in a dose of

> 5mg/5ml

>

> The normal dosing is 1-2mg per kg

>

> 1kg equals 2.2lb

>

> Fran

> Fran Bulone RN

> Mom to ph 7yr

> Waxhaw NC

> /

>

> [Non-text portions of this message have been

> removed]

>

__________________________________________________

August 15, 2006

According to the company info that makes Orapred it should be refrigerated and

will lose potency....

Fran

August 15, 2006

Hi Kathleen,

I've been told that it MUST be refrigerated by one

pharmicist and that it is optional by another - I

refrigerate to be safe. However, we often need to

give a second dose dispite this. I would love to know

what happens to it when it is not refrigerated.

Mom to (5) and Audrey (3 )

--- Kathleen Cunningham <kjbcunningham@...>

wrote:

> Uh-oh, the pharmicist told me that refrigeration for

> Orapred was optional and I don't refrig. mine - does

> this make it lose its effectiveness? I have an

> unopened bottle that came from the pharmacy not

> refrigerated. Should I refrigerate it after

> opening? We have noticed a change in our son's

> response to the drug (e.g. needing more than one

> dose to eliminate a fever cycle) so I'm worried that

> it may be due to something as simple as lack of

> refrigeration???

>

> Any responses would be greatly appreciated!

> Kathleen

>

> Henry <heatherp_87@...> wrote:

> Orapred now comes in 15mg/5ml. That is

> what we use.

> Also, it is MUCH better tasting, as least to Audrey.

>

> She doesn't fight with us half as much as she did

> with

> the generic. It is worth the extra money. The only

> down side is that it requires refrigeration.

>

> Mother to (5) and Audrey (3 )

>

> --- Fran Bulone <fbulone@...> wrote:

>

> > Prednisone and Orapred ONLY comes in a dose of

> > 5mg/5ml

> >

> > The normal dosing is 1-2mg per kg

> >

> > 1kg equals 2.2lb

> >

> > Fran

> > Fran Bulone RN

> > Mom to ph 7yr

> > Waxhaw NC

> > /

> >

> > [Non-text portions of this message have been

> > removed]

> >

>

> __________________________________________________

>

August 15, 2006

Hi Again

Just went to the orapred.com site and checked out the info packet pdf file. It

states the medication must be refrigerated.

I went ahead and wrote to the company to get more information for all of you

questioning the info packet information and getting different advise from

pharmacists.

Will update as soon as I get more info.

Fran

Fran Bulone RN

Mom to ph 7yr

Waxhaw NC

/

August 15, 2006

We use Orapred for our son.

And for the first few years, I had no idea it had to be kept in the

refrigerator. It was not labeled on the bottle, the doctor did not

tell me to and the pharmacist did not tell me to. So I kept it in

the medicine cabinet.

Also it is interesting to note that one bottle lasted me over 2

years, so the expiration date had come and gone. And according to

several doctors, (including the infectious disease specialist we

saw), Orapred is effective for long after a year. If it looses any

effectiveness, it is very very minimal.

Anyway, despite being expired and not being refrigerated, my son's

fever always " vanished " within one hour of taking it.

I do keep it in the refrigerator now, but I don't feel uncomforable

about traveling with it and keeping it in a hotel room for a few

days while on vacation unrefrigerated. Then it goes back into the

fridge when we get home.

So in our experience not keeping it in the fridge did not change the

effectiveness of the Orapred.

Hope this helps. in Tampa, Mom to Jonah 5 years old.

> >

> > > Prednisone and Orapred ONLY comes in a dose of

> > > 5mg/5ml

> > >

> > > The normal dosing is 1-2mg per kg

> > >

> > > 1kg equals 2.2lb

> > >

> > > Fran

> > > Fran Bulone RN

> > > Mom to ph 7yr

> > > Waxhaw NC

> > > /

> > >

> > > [Non-text portions of this message have been

> > > removed]

> > >

> >

> > __________________________________________________

> >

August 15, 2006

FYI

We have used Orapred not for , but for many other things in all three of

our children and our doc has always said it does not have to be refrigerated but