Guest guest Posted January 11, 2005 Report Share Posted January 11, 2005 > > It seams that Switzerland has made a connection between Lyme, and MS. > Hope this may help > > > > > Med Hypotheses. 2005;64(3):438-48. > > > Chronic Lyme borreliosis at the root of multiple sclerosis - is a > cure with antibiotics attainable? > Fritzsche M. > > Clinic for Internal and Geographical Medicine, Soodstrasse 13, 8134 > Adliswil, Switzerland. > > Apart from its devastating impact on individuals and their families, > multiple sclerosis (MS) creates a huge economic burden for society by > mainly afflicting young adults in their most productive years. > Although effective strategies for symptom management and disease > modifying therapies have evolved, there exists no curative treatment > yet. Worldwide, MS prevalence parallels the distribution of the Lyme > disease pathogen Borrelia (B.) burgdorferi, and in America and Europe, > the birth excesses of those individuals who later in life develop MS > exactly mirror the seasonal distributions of Borrelia transmitting > Ixodes ticks. > > In addition to known acute infections, no other disease exhibits > equally marked epidemiological clusters by season and locality, > nurturing the hope that prevention might ultimately be attainable. As > minocycline, tinidazole and hydroxychloroquine are reportedly capable > of destroying both the spirochaetal and cystic L-form of B. > burgdorferi found in MS brains, there emerges also new hope for those > already afflicted. The immunomodulating anti-inflammatory potential of > minocycline and hydroxychloroquine may furthermore reduce the Jarisch > Herxheimer reaction triggered by decaying Borrelia at treatment > initiation. > > Even in those cases unrelated to B. burgdorferi, minocycline is known > for its beneficial effect on several factors considered to be > detrimental in MS. Patients receiving a combination of these > pharmaceuticals are thus expected to be cured or to have a longer > period of remission compared to untreated controls. Although the goal > of this rational, cost-effective and potentially curative treatment > seems simple enough, the importance of a scientifically sound approach > cannot be overemphasised. A randomised, prospective, double blinded > trial is necessary in patients from B. burgdorferi endemic areas with > established MS and/or Borrelia L-forms in their cerebrospinal fluid, > and to yield reasonable significance within due time, the groups must > be large enough and preferably taken together in a multi-centre study. > > Regards > Jim > www.canlyme.com Quote Link to comment Share on other sites More sharing options...
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