RE: Calcium intake increases risk of prostate cancer among Singapore Chinese.

[Guest guest]

Jeff: how does this translate to what we should eat? We certainly don’t want to give up veggies.

And it sounds like CRONIES because of low body mass would qualify for being more “at risk”.

On 8/9/10 1:59 PM, " Novick " <jnovickrd@...> wrote:

(thanks to Al for posting this on another list)

Calcium intake increases risk of prostate cancer among Singapore Chinese.

LM, Wong AS, Koh WP, Wang R, Yuan JM, Yu MC.

Cancer Res. 2010 Jun 15;70(12):4941-8. Epub 2010 Jun 1.

PMID: 20516117

Abstract

Consumption of dairy products, the primary source of calcium in Western diets, has been found to be positively associated with prostate cancer. In an Asian diet, nondairy foods are the major contributors of calcium. Thus, a study of dietary calcium and prostate cancer in Asians can better inform on whether calcium, as opposed to other dairy components, is responsible for the dairy foods-prostate cancer association.

We examined calcium intake and prostate cancer risk among 27,293 men in the Singapore Chinese Health Study that was established between 1993 and 1998.

As of December 31, 2007, 298 incident prostate cancer cases had been diagnosed among the cohort members. Diet was assessed at baseline with a validated 165-item food-frequency questionnaire. It is hypothesized that there is greater net absorption of calcium in smaller individuals. Therefore, the calcium-prostate cancer association was also assessed in stratified analyses by median body mass index.

Vegetables were the largest contributor of daily calcium intake in the study population. Overall, we observed a modest, statistically nonsignificant 25% increase in prostate cancer risk for the 4th (median = 659 mg/d) versus 1st (median = 211 mg/d) quartiles of calcium intake after adjustment for potential confounders. The association became considerably stronger and achieved statistical significance (hazard ratio, 2.03; 95% confidence interval, 1.23-3.34; P for trend = 0.01) for men with a below median body mass index (22.9 kg/m(2)). Dietary calcium might be a risk factor for prostate cancer even at relatively low intake.

[Guest guest]

According to this study, maybe

veggies are bad for us after all...

Steve

From:

[mailto: ] On Behalf Of Francesca Skelton

Sent: Monday, August 09, 2010 12:02 PM

support group

Subject: Re: [ ] Calcium intake increases risk of prostate

cancer among Singapore Chinese.

Jeff:

how does this translate to what we should eat? We certainly don’t want to

give up veggies.

And it sounds like CRONIES because of low body mass would qualify for being

more “at risk”.

On 8/9/10 1:59 PM, " Novick " <jnovickrd@...> wrote:

(thanks to Al for posting this on another list)

Calcium intake increases risk of prostate cancer among Singapore Chinese.

LM, Wong AS, Koh WP, Wang R, Yuan JM, Yu MC.

Cancer Res. 2010 Jun 15;70(12):4941-8. Epub 2010 Jun 1.

PMID: 20516117

Abstract

Consumption of dairy products, the primary source of calcium in Western diets,

has been found to be positively associated with prostate cancer. In an Asian

diet, nondairy foods are the major contributors of calcium. Thus, a study of

dietary calcium and prostate cancer in Asians can better inform on whether

calcium, as opposed to other dairy components, is responsible for the dairy

foods-prostate cancer association.

We examined calcium intake and prostate cancer risk among 27,293 men in the

Singapore Chinese Health Study that was established between 1993 and 1998.

As of December 31, 2007, 298 incident prostate cancer cases had been diagnosed

among the cohort members. Diet was assessed at baseline with a validated

165-item food-frequency questionnaire. It is hypothesized that there is greater

net absorption of calcium in smaller individuals. Therefore, the

calcium-prostate cancer association was also assessed in stratified analyses by

median body mass index.

Vegetables were the largest contributor of daily calcium intake in the study

population. Overall, we observed a modest, statistically nonsignificant 25%

increase in prostate cancer risk for the 4th (median = 659 mg/d) versus 1st

(median = 211 mg/d) quartiles of calcium intake after adjustment for potential

confounders. The association became considerably stronger and achieved

statistical significance (hazard ratio, 2.03; 95% confidence interval,

1.23-3.34; P for trend = 0.01) for men with a below median body mass index

(22.9 kg/m(2)). Dietary calcium might be a risk factor for prostate cancer even

at relatively low intake.

[Guest guest]

i doubt that vegetables will ever be considered bad for us, but like every other thing in life, excess can have unintended consequences. Somebody who proudly uses his food serving software to keep calories down by eating pounds of leafy greens daily may want to reinspect that practice. life will kill us all eventually... moderation moderation moderation.... JROn Aug 9, 2010, at 2:15 PM, Steve wrote:

According to this study, maybe

veggies are bad for us after all...

Steve

From:

[mailto: ] On Behalf Of Francesca Skelton

Sent: Monday, August 09, 2010 12:02 PM

support group

Subject: Re: [ ] Calcium intake increases risk of prostate

cancer among Singapore Chinese.

Jeff:

how does this translate to what we should eat? We certainly don’t want to

give up veggies.

And it sounds like CRONIES because of low body mass would qualify for being

more “at risk”.

On 8/9/10 1:59 PM, " Novick" <jnovickrd > wrote:

(thanks to Al for posting this on another list)

Calcium intake increases risk of prostate cancer among Singapore Chinese.

LM, Wong AS, Koh WP, Wang R, Yuan JM, Yu MC.

Cancer Res. 2010 Jun 15;70(12):4941-8. Epub 2010 Jun 1.

PMID: 20516117

Abstract

Consumption of dairy products, the primary source of calcium in Western diets,

has been found to be positively associated with prostate cancer. In an Asian

diet, nondairy foods are the major contributors of calcium. Thus, a study of

dietary calcium and prostate cancer in Asians can better inform on whether

calcium, as opposed to other dairy components, is responsible for the dairy

foods-prostate cancer association.

We examined calcium intake and prostate cancer risk among 27,293 men in the

Singapore Chinese Health Study that was established between 1993 and 1998.

As of December 31, 2007, 298 incident prostate cancer cases had been diagnosed

among the cohort members. Diet was assessed at baseline with a validated

165-item food-frequency questionnaire. It is hypothesized that there is greater

net absorption of calcium in smaller individuals. Therefore, the

calcium-prostate cancer association was also assessed in stratified analyses by

median body mass index.

Vegetables were the largest contributor of daily calcium intake in the study

population. Overall, we observed a modest, statistically nonsignificant 25%

increase in prostate cancer risk for the 4th (median = 659 mg/d) versus 1st

(median = 211 mg/d) quartiles of calcium intake after adjustment for potential

confounders. The association became considerably stronger and achieved

statistical significance (hazard ratio, 2.03; 95% confidence interval,

1.23-3.34; P for trend = 0.01) for men with a below median body mass index

(22.9 kg/m(2)). Dietary calcium might be a risk factor for prostate cancer even

at relatively low intake.

[Guest guest]

I hope you’re joking. Veggies (especially certain ones – see our files on cancer) work to prevent cancer. They are the mainstay of any self respecting CRONIE.

This seems to be another nail in the coffin for being too restricted from what I can see. Other opinions welcomed.

Moderation, moderation, moderation – in all things, even (maybe especially) thinness.

On 8/9/10 3:15 PM, " Steve " <stev.alex@...> wrote:

According to this study, maybe veggies are bad for us after all...

Steve

From: [mailto: ] On Behalf Of Francesca Skelton

Sent: Monday, August 09, 2010 12:02 PM

support group

Subject: Re: [ ] Calcium intake increases risk of prostate cancer among Singapore Chinese.

Jeff: how does this translate to what we should eat? We certainly don’t want to give up veggies.

And it sounds like CRONIES because of low body mass would qualify for being more “at risk”.

On 8/9/10 1:59 PM, " Novick " <jnovickrd@...> wrote:

(thanks to Al for posting this on another list)

Calcium intake increases risk of prostate cancer among Singapore Chinese.

LM, Wong AS, Koh WP, Wang R, Yuan JM, Yu MC.

Cancer Res. 2010 Jun 15;70(12):4941-8. Epub 2010 Jun 1.

PMID: 20516117

Abstract

Consumption of dairy products, the primary source of calcium in Western diets, has been found to be positively associated with prostate cancer. In an Asian diet, nondairy foods are the major contributors of calcium. Thus, a study of dietary calcium and prostate cancer in Asians can better inform on whether calcium, as opposed to other dairy components, is responsible for the dairy foods-prostate cancer association.

We examined calcium intake and prostate cancer risk among 27,293 men in the Singapore Chinese Health Study that was established between 1993 and 1998.

As of December 31, 2007, 298 incident prostate cancer cases had been diagnosed among the cohort members. Diet was assessed at baseline with a validated 165-item food-frequency questionnaire. It is hypothesized that there is greater net absorption of calcium in smaller individuals. Therefore, the calcium-prostate cancer association was also assessed in stratified analyses by median body mass index.

Vegetables were the largest contributor of daily calcium intake in the study population. Overall, we observed a modest, statistically nonsignificant 25% increase in prostate cancer risk for the 4th (median = 659 mg/d) versus 1st (median = 211 mg/d) quartiles of calcium intake after adjustment for potential confounders. The association became considerably stronger and achieved statistical significance (hazard ratio, 2.03; 95% confidence interval, 1.23-3.34; P for trend = 0.01) for men with a below median body mass index (22.9 kg/m(2)). Dietary calcium might be a risk factor for prostate cancer even at relatively low intake.

[Guest guest]

Definitely joking. What

would I eat without veggies? Oh, I guess there’s chocolate. Is chocolate a

vegetable?

I’d go along with the

moderation thing. And thinness is somewhat overrated, IMO, especially in young

women. Talk about skinny! For a healthy looking

person, I’d take the “standard” tables and add about 10-20 lbs. Personally, I happen

to fit the standard tables, but I feel for those who don’t.

Steve

From:

[mailto: ] On Behalf Of Francesca Skelton

Sent: Monday, August 09, 2010 12:56 PM

support group

Subject: Re: [ ] Calcium intake increases risk of prostate

cancer among Singapore Chinese.

I

hope you’re joking. Veggies (especially certain ones – see our files on

cancer) work to prevent cancer. They are the mainstay of any self

respecting CRONIE.

This seems to be another nail in the coffin for being too restricted from what

I can see. Other opinions welcomed.

Moderation, moderation, moderation – in all things, even (maybe especially)

thinness.

On 8/9/10 3:15 PM, " Steve " <stev.alex@...>

wrote:

According to this study, maybe

veggies are bad for us after all...

Steve

From: [mailto: ]

On Behalf Of Francesca Skelton

Sent: Monday, August 09, 2010 12:02 PM

support group

Subject: Re: [ ] Calcium intake increases risk of prostate

cancer among Singapore Chinese.

Jeff: how does this translate to

what we should eat? We certainly don’t want to give up veggies.

And it sounds like CRONIES because of low body mass would qualify for being

more “at risk”.

On 8/9/10 1:59 PM, " Novick " <jnovickrd@...>

wrote:

(thanks to Al for posting this on another list)

Calcium intake increases risk of prostate cancer among Singapore Chinese.

LM, Wong AS, Koh WP, Wang R, Yuan JM, Yu MC.

Cancer Res. 2010 Jun 15;70(12):4941-8. Epub 2010 Jun 1.

PMID: 20516117

Abstract

Consumption of dairy products, the primary source of calcium in Western diets,

has been found to be positively associated with prostate cancer. In an Asian

diet, nondairy foods are the major contributors of calcium. Thus, a study of

dietary calcium and prostate cancer in Asians can better inform on whether

calcium, as opposed to other dairy components, is responsible for the dairy

foods-prostate cancer association.

We examined calcium intake and prostate cancer risk among 27,293 men in the

Singapore Chinese Health Study that was established between 1993 and 1998.

As of December 31, 2007, 298 incident prostate cancer cases had been diagnosed

among the cohort members. Diet was assessed at baseline with a validated

165-item food-frequency questionnaire. It is hypothesized that there is greater

net absorption of calcium in smaller individuals. Therefore, the

calcium-prostate cancer association was also assessed in stratified analyses by

median body mass index.

Vegetables were the largest contributor of daily calcium intake in the study

population. Overall, we observed a modest, statistically nonsignificant 25%

increase in prostate cancer risk for the 4th (median = 659 mg/d) versus 1st

(median = 211 mg/d) quartiles of calcium intake after adjustment for potential

confounders. The association became considerably stronger and achieved

statistical significance (hazard ratio, 2.03; 95% confidence interval,

1.23-3.34; P for trend = 0.01) for men with a below median body mass index

(22.9 kg/m(2)). Dietary calcium might be a risk factor for prostate cancer even

at relatively low intake.

[Guest guest]

If you search for other studies, you get enough information to not be

particularly concerned with the Singapore study.

For example, " Diet, Supplement Use, and Prostate Cancer Risk: Results From the

Prostate Cancer Prevention Trial " found that dietary calcium (but not

supplemental calcium) was associated with increased risk of low-grade prostate

cancer, but REDUCED risk of high-grade prostate cancer.

Another article, " Dairy products and prostate cancer risk " suggests that it is

only in dairy products that the increased prostate cancer risk is found, and

that is due to the high levels of phosphate in dairy products.

Searching for other articles on pubmed would probably lead to other reasons to

calm down about this.

Bruce