Beta-Alanine for workout recovery

[Guest guest]

Beta-Alanine is supposed to be great for workout recovery.

http://www.betaalanine.info/

Is there any validity to this?

It’s not for me, it’s for a tired, worn out, raggedy assed, thinks he’s still 25, workout driven older guy.

This friend bought the Amino Acid powder to try and he doesn’t seem to notice much affect but he’s giving it some time.

AminoBoost XXL: Increase muscle protein synthesis, activates new muscle growth, be smarter, get a giant chest, GET HUGE AND BE SOMEBODY, improves recovery from intense training.

http://www.dotfit.com/aminoboostxxl

--

E. Abrahamson, D.C.

Chiropractic physician

Lake Oswego Chiropractic Clinic

315 Second Street

Lake Oswego, OR 97034

503-635-6246

Website: http://www.lakeoswegochiro.com

[Guest guest]

Don't forget weight loss and the wallet will feel lighterAlan , D.C743 Lawrence StEugene, OR 97401-2501541.343.1942alansmithdc@...To: From: drscott@...Date: Mon, 19 Dec 2011 18:48:05 -0800Subject: Beta-Alanine for workout recovery

Beta-Alanine is supposed to be great for workout recovery.

http://www.betaalanine.info/

Is there any validity to this?

It’s not for me, it’s for a tired, worn out, raggedy assed, thinks he’s still 25, workout driven older guy.

This friend bought the Amino Acid powder to try and he doesn’t seem to notice much affect but he’s giving it some time.

AminoBoost XXL: Increase muscle protein synthesis, activates new muscle growth, be smarter, get a giant chest, GET HUGE AND BE SOMEBODY, improves recovery from intense training.

http://www.dotfit.com/aminoboostxxl

--

E. Abrahamson, D.C.

Chiropractic physician

Lake Oswego Chiropractic Clinic

315 Second Street

Lake Oswego, OR 97034

503-635-6246

Website: http://www.lakeoswegochiro.com

[Guest guest]

:

Here is what Wikipedia says about b-alanine (see below).

Lyndon McGill, D.C.

Salem, Oregon

www.SalemSpineClinic.com

www.LimitlessRelief.com

β-Alanine (or beta-alanine) is a naturally

occurring beta amino acid,

which are amino acids in which

the amino group is at the β-position from

the carboxylate group (i.e., two atoms away, see Figure 1). The IUPAC name for β-alanine would be 3-aminopropanoic

acid. Unlike its normal counterpart, α-alanine,

β-alanine has no chiral center.

β-Alanine is not used in the biosynthesis of any major proteins

or enzymes.

It is formed in vivo by the degradation of dihydrouracil and carnosine.

It is a component of the naturally occurring peptides carnosine and anserine

and also of pantothenic acid (vitamin B5)

which itself is a component of coenzyme A. Under normal conditions, β-alanine is metabolized into acetic acid.

β-Alanine is the rate-limiting precursor of carnosine,

which is to say carnosine levels are limited by the amount of

available β-alanine. Supplementation with

β-alanine has been shown to increase the concentration of

carnosine in muscles, decrease fatigue in athletes and increase

total muscular work done.[3][4]

Figure 1: Comparison of β-alanine (right) with the more

customary (chiral) amino acid, L-α-alanine

(left)

Typically studies have used supplementing strategies of multiple

doses of 400 mg or 800 mg, administered at regular intervals for

up to eight hours, over periods ranging from 4 to 10 weeks.[4][5]

After a 10 week supplementing strategy, the reported increase in

intramuscular carnosine content was an average of 80.1% (range 18

to 205%).[4]

L-Histidine, with a pKa of 6.1 is a

relatively weak buffer over the physiological intramuscular pH

range. However, when bound to other amino acids this increases

nearer to 6.8-7.0. In particular, when bound to β-alanine the pKa

value is 6.83,[6]

making this a very efficient intramuscular buffer. Furthermore,

because of the position of the beta amino group, β-alanine

dipeptides are not incorporated proteins and thus can be stored at

relatively high concentrations (millimolar). Occurring at

17-25 mmol/kg (dry muscle),[7]

carnosine (β-alanyl-L-histidine) is an important

intramuscular buffer, constituting 10-20% of the total buffering

capacity in type I and II muscle fibres.

β-Alanine, provided in solution or as powder in gelatine

capsules, however, causes paraesthesia when

ingested in amounts above 10 mg per kg body weight (bwt).[5]

This is variable between individuals. Symptoms may be experienced

by some individuals as mild even at 10 mg per kg bwt, in a

majority as significant at 20 mg per kg bwt, and severe at 40 mg

per kg bwt.[5]

However, an equivalent amount (equimolar) to 40 mg per kg bwt,

ingested in the form of histidine containing dipeptides in chicken

broth extract, did not cause paraesthesia.[5]

It is probable that the paraesthesia, a

form of neuropathic pain, results from high peak blood-plasma

concentrations of β-alanine since greater quantities, ingested in

the form of the β-alanine / histidine (or methylhistidine)

containing dipeptides (i.e. carnosine and anserine) in meat, do

not cause the same symptoms. In this case the β-alanine absorption

profile is flattened but sustained for a longer period of time,[5]

whereas, the β-alanine samples in the studies were administered as

gelatine capsules containing powder. This resulted in plasma

concentrations rising rapidly, peaking within 30 to 45 minutes,

and being eliminated after 90 to 120 minutes. The paraesthesia

caused is no indication of efficacy since the published studies

undertaken so far have utilised doses of 400 mg or 800 mg at a

time to avoid the paraesthesia. Furthermore, excretion of

β-alanine in urine accounted for 0.60%(+/-0.09), 1.50%(+/-0.40)

and 3.64%(+/-0.47) of the administered doses of 10, 20, or 40 mg

per kg body weight,[5]

indicating greater losses occurring with increasing dosage.

Even though much weaker than glycine

(and thus with a debated role as a physiological transmitter),

β-alanine is an agonist next in activity to the cognate ligand

glycine itself, for strychnine-sensitive inhibitory glycine receptors (GlyRs) (the

agonist order: glycine >> β-alanine > taurine >>

alanine, L-serine > proline).[8]

On 12/19/2011 6:48 PM, Abrahamson wrote:

Beta-Alanine is supposed to

be great for workout recovery.

http://www.betaalanine.info/

Is there any validity to this?

It’s not for me, it’s for a tired, worn out, raggedy

assed, thinks he’s still 25, workout driven older guy.

This friend bought the Amino Acid powder to try and he

doesn’t seem to notice much affect but he’s giving it

some time.

AminoBoost XXL:

Increase muscle protein synthesis, activates new

muscle growth, be smarter, get a giant chest, GET

HUGE AND BE SOMEBODY, improves recovery from intense

training.

http://www.dotfit.com/aminoboostxxl

--

E. Abrahamson, D.C.

Chiropractic physician

Lake Oswego Chiropractic Clinic

315 Second Street

Lake Oswego, OR 97034

503-635-6246

Website: http://www.lakeoswegochiro.com