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Do Antidepressants Cure or Create Abnormal Brain States?

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Entire article can be read by clicking on the URL

Gill

http://medicine.plosjournals.org/perlserv/?request=get-document & doi=10%2E1371%

2Fjournal%2Epmed%2E0030240

Do Antidepressants Cure or Create Abnormal Brain States?

Joanna Moncrieff*, Cohen

Joanna Moncrieff is a senior lecturer in Psychiatry, University College

London, London, United Kingdom. Cohen is a professor at the School

of Social Work, College of Health and Urban Affairs, Florida

International University, Miami, Florida, United States of America.

Article Summary

Antidepressants are assumed to work on the specific neurobiology of

depressive disorders according to a “disease-centred†model of drug

action. However, little evidence supports this idea. An alternative,

“drug-centred,†model suggests that psychotropic drugs create abnormal

states that may coincidentally relieve symptoms. Drug-induced effects of

antidepressants vary widely according to their chemical class—from

sedation and cognitive impairment to mild stimulation and occasionally

frank agitation. Results of clinical trials may be explained by

drug-induced effects and placebo amplification. No evidence shows that

antidepressants or any other drugs produce long-term elevation of mood

or other effects that are particularly useful in treating depression.

(See Text S1 for French translation.)

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You have no idea.... I take Effexor for panic and anxiety only now I panic and

have anxiety attacks if I forget to take it because it screws my head up so bad.

Explain that. So now I am stuck taking this crap. I can honestly say all these

new meds are at least in part created to keep you on them, but God forbid you

break your leg and ask for pain meds, see these are to addictive. Please....

LymeAngl@... wrote: Entire article can be read by clicking on the

URL

Gill

http://medicine.plosjournals.org/perlserv/?request=get-document & doi=10%2E1371%

2Fjournal%2Epmed%2E0030240

Do Antidepressants Cure or Create Abnormal Brain States?

Joanna Moncrieff*, Cohen

Joanna Moncrieff is a senior lecturer in Psychiatry, University College

London, London, United Kingdom. Cohen is a professor at the School

of Social Work, College of Health and Urban Affairs, Florida

International University, Miami, Florida, United States of America.

Article Summary

Antidepressants are assumed to work on the specific neurobiology of

depressive disorders according to a “disease-centred†model of drug

action. However, little evidence supports this idea. An alternative,

“drug-centred,†model suggests that psychotropic drugs create abnormal

states that may coincidentally relieve symptoms. Drug-induced effects of

antidepressants vary widely according to their chemical class—from

sedation and cognitive impairment to mild stimulation and occasionally

frank agitation. Results of clinical trials may be explained by

drug-induced effects and placebo amplification. No evidence shows that

antidepressants or any other drugs produce long-term elevation of mood

or other effects that are particularly useful in treating depression.

(See Text S1 for French translation.)

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Gives me a server error??

Lourdes Salvador <salvadorlourdes@...> wrote: This link did not

work. Can you check it?

Lourdes " Sal " Salvador, salvadorlourdes@...

Subject: [] Do Antidepressants Cure or Create Abnormal Brain

States?

Entire article can be read by clicking on the URL

Gill

http://medicine.plosjournals.org/perlserv/?request=get-document & doi=10%2E1371%

2Fjournal%2Epmed%2E0030240

Life is a balance of holding on and letting go...

__________________________________________________

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Here it is..

http://medicine.plosjournals.org/perlserv/?request=get-document & doi=10%2E1371%2F\

journal%2Epmed%2E0030240

Lourdes Salvador <salvadorlourdes@...> wrote:

This link did not work. Can you check it?

Lourdes " Sal " Salvador, salvadorlourdes@...

Subject: [] Do Antidepressants Cure or Create Abnormal Brain

States?

Entire article can be read by clicking on the URL

Gill

http://medicine.plosjournals.org/perlserv/?request=get-document & doi=10%2E1371%

2Fjournal%2Epmed%2E0030240

Life is a balance of holding on and letting go...

__________________________________________________

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