Drug induced Hepatitis can be fatal

[Guest guest]

Apparently drug induced hepatitis is very serious, so take care of

your liver.

From Indiana Journal of Dermatology

A 57 year old woman dies of drug induced hepatitis and rash:

http://tinyurl.com/r9dgl

ABSTRACT: A 57 year old female presented with

generalized erythematous scaly plaques of one and

half months duration and jaundice since 1 month.

She was on leflunomide since 3 months for chronic

rheumatoid arthritis. Investigations revealed

positive ANA, rheumatoid factor and negative

anti-DsDNA. Bilirubin and liver enzymes were

markedly raised. Viral markers were negative.

Direct immunoflourescence did not show lupus

band. A diagnosis of drug induced hepatitis and

skin rash was made. She was treated with

cholestyramine but she died after ten days of

hospitalisation.

Uppal M, Rai R, Srinivas C,. Leflunomide induced drug rash and

hepatotoxicity.Indian J Dermatol 2004;49:154-155