Re: Honey betters microflora, reduces toxicity of mycotoxins

[Guest guest]

very interesting KC, thanks

>

> Honey betters microflora, reduces toxicity of mycotoxins

>

> By Aly M Ezz El-Arab , Shenouda M Girgis , Eman M Hegazy and Azzat

B

> Abd El-Khalek

> Mar 30, 2006, 00:44

> Lisle,IL

>

>

http://www.foodconsumer.org/777/8/Honey_betters_microflora_reduces_to

> xicity_of_mycotoxins.shtml

>

> Research article

>

> Effect of dietary honey on intestinal microflora and toxicity of

> mycotoxins in mice

>

> Aly M Ezz El-Arab , Shenouda M Girgis , Eman M Hegazy and Azzat B

> Abd El-Khalek

>

> BMC Complementary and Alternative Medicine 2006, 6:6

> doi:10.1186/1472-6882-6-6

>

> Published 14 March 2006

>

> Abstract (provisional)

>

> Background

>

> Bee honey is a functional food which has a unique composition,

> antimicrobial properties and bifidogenic effect. In order to assess

> whether honey can inhibit the toxic effect of mycotoxins, the

> present study was undertaken.

>

> Methods

>

> Production of biomass and toxins by Aspergillus parasiticus and

> Aspergillus ochraceus were followed in media without and with

honey.

> Although aflatoxins and ochratoxin A. were administrated to male

> Swiss albino mice up to 1ug and 10 ng /kg body weight / day

> respectively. The experimental animals were fed diets without our

> with 10% honey for two months. The changes in colonic probiotic

> bacteria, determintal colon enzyme glucuronidases, and genotoxicity

> were followed.

>

> Results

>

> Addition of 32% in its media increased the biomass of A

parasiticus,

> while the biomass of A. ochraceus decreased and Ochratoxin A. was

> not produced. When the honey was added at the ratio of 32 and 48%

in

> the medium. No relationship was found between mycelium weight and

> production of mycotoxins. Oral administration of aflatoxins

(mixture

> of B1, B2, G1 and G2 ) and Ochratoxin A. induced structural and

> numerical chromosomal aberrations in bone marrow and germ cells of

> male mice. Also both toxins induced histopathological changes in

> liver and kidney. Feeding on diet supplemented with honey improved

> the histopathological changes in case of aflatoxin group, but not

in

> the case of ochratoxin A. group (except of kidney in two cases). No

> significant differences were found in the activity of colon -

> glucuronidase between group fed diet with or without honey. On the

> other hand, the colon bifido bacteria and lactobacilli counts were

> increased markedly in group receiving diet supplemented with honey.

>

> Conclusions

>

> Substituting sugars with honey in processed food can inhibit the

> harmful effect of mycotoxins, and improve the gut microflora

>

> Source: http://www.biomedcentral.com/

>