Re: Incidence of Vit D deficiency

March 13, 2006

Goldner, W.S., O'Dorisio, T.M., Dillon, J.S. and Mason, E.E. (2002).

Severe Metabolic Bone Disease as a Long-Term Complication of Obesity

Surgery, Obesity Surgery, 12, 685-692.

Editorial: Bone Loss and Gastric Bypass Surgery for Morbid Obesity.

The Journal of Clinical Endocrinology & Metabolism 89(3):1059–1060.

Ott MT, Fanti P, Malluche HH, Ryo UY, Whaley FS, Strodel WE, Colacchi

TA 1992 Biochemical evidence of metabolic bone disease in women

following Roux-Y gastric bypass for morbid obesity. Obes Surg 2:341–

348

Pugnale N, Giusti V, Suter M, Zysset F, Heraief E, Gaillard RC,

Burckhardt P 2003 Bone metabolism and risk of secondary

hyperparathyroidism 12 months after gastric banding in obese pre-

menopausal women. Int J Obes Relat Metab Disord 27:110–116

Guney E, Kisakol G, Ozgen G, Yilmaz C, Yilmaz R, Kabalak T 2003

Effect of weight loss on bone metabolism: comparison of vertical

banded gastroplasty and medical intervention. Obes Surg 13:383–388

Bell NH, Epstein S, Greene A, Shary J, Oexmann MJ, Shaw S 1985

Evidence for alteration of the vitamin D-endocrine system in obese

subjects. J Clin Invest 76:370–373

Liel Y, Ulmer E, Shary J, Hollis BW, Bell NH 1988 Low circulating

vitamin D in obesity. Calcif Tissue Int 43:199–201

Compston JRE, Vedi S, Ledger JE, Webb A, Gazet JC, Pilkington TR 1981

Vitamin D status and bone histomorphometry in gross obesity. AmJ

Clin Nutr 34:2359–2363

Parfitt AM, Podenphant J, Villanueva AR, Frame B 1985 Metabolic bone

diseases with and without osteomalacia after intestinal bypass

surgery: a bone histomorphometric study. Bone 6:211–220

van Loan MD, HL, Barbieri TF 1998 Effect of weight loss on

bone mineral content and bone mineral density in obese women. Am J

Clin Nutr 67:734–738

Coates PS, Fernstrom JD, Fernstrom MH, Schauer PR, Greenspan SL 2004

Gastric bypass surgery for morbid obesity leads to an increase in

bone turnover and a decrease in bone mass. J Clin Endocrinol Metab

89:1061–1065

Goldner, W.S., O'Dorisio, T.M., Dillon, J.S. and Mason, E.E. (2002).

Severe Metabolic Bone Disease as a Long-Term Complication of Obesity

Surgery, Obesity Surgery, 12, 685-692.

Editorial: Bone Loss and Gastric Bypass Surgery for Morbid Obesity.

The Journal of Clinical Endocrinology & Metabolism 89(3):1059–1060.

Ott MT, Fanti P, Malluche HH, Ryo UY, Whaley FS, Strodel WE, Colacchi

TA 1992 Biochemical evidence of metabolic bone disease in women

following Roux-Y gastric bypass for morbid obesity. Obes Surg 2:341–

348

Pugnale N, Giusti V, Suter M, Zysset F, Heraief E, Gaillard RC,

Burckhardt P 2003 Bone metabolism and risk of secondary

hyperparathyroidism 12 months after gastric banding in obese pre-

menopausal women. Int J Obes Relat Metab Disord 27:110–116

Guney E, Kisakol G, Ozgen G, Yilmaz C, Yilmaz R, Kabalak T 2003

Effect of weight loss on bone metabolism: comparison of vertical

banded gastroplasty and medical intervention. Obes Surg 13:383–388

Bell NH, Epstein S, Greene A, Shary J, Oexmann MJ, Shaw S 1985

Evidence for alteration of the vitamin D-endocrine system in obese

subjects. J Clin Invest 76:370–373

Liel Y, Ulmer E, Shary J, Hollis BW, Bell NH 1988 Low circulating

vitamin D in obesity. Calcif Tissue Int 43:199–201

Compston JRE, Vedi S, Ledger JE, Webb A, Gazet JC, Pilkington TR 1981

Vitamin D status and bone histomorphometry in gross obesity. AmJ

Clin Nutr 34:2359–2363

Parfitt AM, Podenphant J, Villanueva AR, Frame B 1985 Metabolic bone

diseases with and without osteomalacia after intestinal bypass

surgery: a bone histomorphometric study. Bone 6:211–220

van Loan MD, HL, Barbieri TF 1998 Effect of weight loss on

bone mineral content and bone mineral density in obese women. Am J

Clin Nutr 67:734–738

Coates PS, Fernstrom JD, Fernstrom MH, Schauer PR, Greenspan SL 2004

Gastric bypass surgery for morbid obesity leads to an increase in

bone turnover and a decrease in bone mass. J Clin Endocrinol Metab

89:1061–1065

Ava

Lap RNY 4/21/04

245/122

The Ohio State University Medical Center

>

> We routinely check Vit D levels pre-operatively and have been

detecting

> a high incidence of deficiency (about 80%). Our Medical Director

is

> who is an Endocrinologist, is finding a much lower incidence of

Vit D

> deficiency in her clinic population. I was wondering if anyone is

> aware of any literature regarding the incidence of Vit D

deficiency in

> the morbidly obese. I've not been able to find much in my

searches.

> Thanks in advance for any replies!!

>

> Patti

>

March 13, 2006

Posted here previously:

From: " DIANE R. JAVELLI " <djav>

Date: Tue Feb 7, 2006 12:17 pm

Subject: Re: Vitamin D Deficiency

We recently had a MD talk to our RD's about Vitamin D deficiency.

They actually recommend as much as 50,000 weekly to three times per

week for 6-8 weeks dependent on degree of deficiency. And then

maintenance dosage after that: 1000 IU per day or more. Should be

cholecalciferol form only. Also, make sure test done is 25 OH

vitamin D. 1,25(OH)2 vitamin D not good measure of vitamin

D status. A good resource for you might be www.cholecalciferol-

council.com. They have research and recs. that are a little

different than the above info. but more than standard 1000 IU. I

personally have not had any pts to try this on, but some of our

other RD's have worked with the MD on dosing pts and are having good

success, including a gastric bypass pt.

------------------------------

As an RNY pt. currently dealing with Vit. D deficiency, I've just

discovered that the Rx ordered by my PCP is Vit. D2 in vegetable oil

(50,000 IU). RNY pts. have some trouble converting the D2 into D3,

yet D3 is what we need. Plus, we may malabsorb oil-based vites, so

dry Vit. D3 is recommended.

Ava

Lap RNY 4/21/04

245/122

The Ohio State Medical Center

>

> Excellent question. How valid are measuring vit D levels and do

they represent dietary intake?

> thanks

> Nazy

>

> Incidence of Vit D

deficiency

>