Splitting the Gleevec pill

[Guest guest]

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

I called Novartis, and they said we do not recommend unless you doctor

approves it.

_____

From: [mailto: ] On Behalf Of Tammy

Ferns

Sent: Friday, June 06, 2008 11:58 AM

Subject: [ ] Splitting the Gleevec pill

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

I would not mess with success..

Sharon T

_____

From: [mailto: ] On Behalf Of Tammy

Ferns

Sent: Friday, June 06, 2008 9:06 AM

Subject: RE: [ ] Splitting the Gleevec pill

I called Novartis, and they said we do not recommend unless you doctor

approves it.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: Friday, June 06, 2008 11:58 AM

groups (DOT) <mailto:%40> com

Subject: [ ] Splitting the Gleevec pill

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

I have been on 200mg of Gleevec since May of 07' and I have had no

problems with splitting a 400mg pill.

I know some may take issue with only being on 200mg so before anyone

comments: I have been on 200mg since May 07' and my PCR tests have

been great my last test was .0029. The reason for 200mg is becasue I

suffered from severe neutropenia at 400mg and 300mg and was constantly

on and off gleevec. My onc suggested trying 200mg before moving on to

another drug, and I have been doing well ever since.

e

DX 2006

[Guest guest]

e,

You had a very good reason to do it. I am so glad that worked for you.

I just wouldn't mess with my dosage if I was doing fine. But maybe Tammy

has more side effects then she has told us. If so then I say go for it.

And everyone reacts differently to the medication.

Sharon T

_____

From: [mailto: ] On Behalf Of

jonesdjkj

Sent: Friday, June 06, 2008 9:57 AM

Subject: [ ] Re: Splitting the Gleevec pill

I have been on 200mg of Gleevec since May of 07' and I have had no

problems with splitting a 400mg pill.

I know some may take issue with only being on 200mg so before anyone

comments: I have been on 200mg since May 07' and my PCR tests have

been great my last test was .0029. The reason for 200mg is becasue I

suffered from severe neutropenia at 400mg and 300mg and was constantly

on and off gleevec. My onc suggested trying 200mg before moving on to

another drug, and I have been doing well ever since.

e

DX 2006

[Guest guest]

Tammy

Gleevec comes in 100 and 200 mg. tablets anyway. Have your doctor

order that dosage and just split your dosage. When I was on it, they

recommended the split dosage because of its half life. I do think it

is possible. But maybe actually cutting a pill in half is not so

advisable.... You were wise to call Novartis.

Be well

Barb in AZ

>

> I called Novartis, and they said we do not recommend unless you doctor

> approves it.

>

> _____

>

> From: [mailto: ] On Behalf Of

Tammy

> Ferns

> Sent: Friday, June 06, 2008 11:58 AM

>

> Subject: [ ] Splitting the Gleevec pill

>

>

>

> Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a

time

> to avoid having to eat a huge bready meal. Thank you,

> Tammy

> P.S. When I called my onc she said " Go ahead and try that for now, and

I'll

> research it and if I find any issues I'll call you. "

> ---I'm not getting a happy feeling.

>

>

[Guest guest]

Hello,

I'm new here so hopefully this info is ok to post..I read on the

Gleevec webpage that it was ok to disolve the pills in water and it

least the EXACT amounts to use.It said not to cut them..I have no

personal experience though..Good luck..I asked my Dr for the 100mg

pills..I take them 4 times aday..

SharonS

In , " Tammy Ferns " <tammy@...> wrote:

>

> I called Novartis, and they said we do not recommend unless you

doctor

> approves it.

>

> _____

>

> From: [mailto: ] On Behalf

Of Tammy

> Ferns

> Sent: Friday, June 06, 2008 11:58 AM

>

> Subject: [ ] Splitting the Gleevec pill

>

>

>

> Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at

a time

> to avoid having to eat a huge bready meal. Thank you,

> Tammy

> P.S. When I called my onc she said " Go ahead and try that for now,

and I'll

> research it and if I find any issues I'll call you. "

> ---I'm not getting a happy feeling.

>

>

[Guest guest]

Hi when I first got Dx in 2003 I was taking 200mg twice & nbsp;a day, due to my

stomach not being able to take all 400mg at one time. My doctor prescribed me

Gleevec 100mg for me to take 2 in the morning and 2 in the afternoon. Which

worked great for me unfortunately not so great for my & nbsp;CML after about 2

years of dividing my dosage and my BCR still positive my doctor suggested I try

taking all 400mg at once, which I did and after already taking Gleevec

for & nbsp;2 years & nbsp;I was able to tolerate all 400mg at once and most

importantly & nbsp;6 months after my BCR was finally negative , and & nbsp; that's

what I have been doing since then, and thankfully it has been working. I hope

that helps

& nbsp;

- 27

DX 2003

From: Tammy Ferns & lt;tammy@... & gt;

Subject: [ ] Splitting the Gleevec pill

Date: Friday, June 6, 2008, 8:58 AM

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

Hi Tammy,

That's a remarkable answer. Why would they score the pill if they didn't

want you to take half of it?

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of Tammy

Ferns

Sent: June 6, 2008 12:06 PM

Subject: RE: [ ] Splitting the Gleevec pill

I called Novartis, and they said we do not recommend unless you doctor

approves it.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: Friday, June 06, 2008 11:58 AM

groups (DOT) <mailto:%40> com

Subject: [ ] Splitting the Gleevec pill

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

O!!! YIPPEEE!!!

Number 1194 in the Zero Club

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of

jonesdjkj

Sent: June 6, 2008 12:57 PM

Subject: [ ] Re: Splitting the Gleevec pill

I have been on 200mg of Gleevec since May of 07' and I have had no

problems with splitting a 400mg pill.

I know some may take issue with only being on 200mg so before anyone

comments: I have been on 200mg since May 07' and my PCR tests have

been great my last test was .0029. The reason for 200mg is becasue I

suffered from severe neutropenia at 400mg and 300mg and was constantly

on and off gleevec. My onc suggested trying 200mg before moving on to

another drug, and I have been doing well ever since.

e

DX 2006

[Guest guest]

I don't know... but the doc called back and said no. She wants all the

medicine working at once. Ugh.

My side effects aren't bad. I was just trying to get rid of the nausea when

taking it. At 400mg it isn't too bad if I eat a lot of bread, but I was

trying to cut back.

Oh well.

_____

From: [mailto: ] On Behalf Of Zavie

miller

Sent: Saturday, June 07, 2008 12:20 AM

Subject: RE: [ ] Splitting the Gleevec pill

Hi Tammy,

That's a remarkable answer. Why would they score the pill if they didn't

want you to take half of it?

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmillersympatico (DOT) <mailto:zmiller%40sympatico.ca> ca

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: June 6, 2008 12:06 PM

groups (DOT) <mailto:%40> com

Subject: RE: [ ] Splitting the Gleevec pill

I called Novartis, and they said we do not recommend unless you doctor

approves it.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: Friday, June 06, 2008 11:58 AM

groups (DOT) <mailto:%40> com

Subject: [ ] Splitting the Gleevec pill

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

Hi Tammy,

I wouldn't give up so easy. Why not write Dr. Druker and pose the question

to him.

Your doctor's answer doesn't make sense. The half life if Gleevec is 18

hours. What this means is that whether you take 1x400 mg pill daily or 2x200

mg pills daily, the Gleevec level is the same all day.

Zavie

Dr. Druker drukerb@...

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of Tammy

Ferns

Sent: June 7, 2008 12:40 AM

Subject: RE: [ ] Splitting the Gleevec pill

I don't know... but the doc called back and said no. She wants all the

medicine working at once. Ugh.

My side effects aren't bad. I was just trying to get rid of the nausea when

taking it. At 400mg it isn't too bad if I eat a lot of bread, but I was

trying to cut back.

Oh well.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Zavie

miller

Sent: Saturday, June 07, 2008 12:20 AM

groups (DOT) <mailto:%40> com

Subject: RE: [ ] Splitting the Gleevec pill

Hi Tammy,

That's a remarkable answer. Why would they score the pill if they didn't

want you to take half of it?

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmillersympatico (DOT) <mailto:zmiller%40sympatico.ca> ca

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: June 6, 2008 12:06 PM

groups (DOT) <mailto:%40> com

Subject: RE: [ ] Splitting the Gleevec pill

I called Novartis, and they said we do not recommend unless you doctor

approves it.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: Friday, June 06, 2008 11:58 AM

groups (DOT) <mailto:%40> com

Subject: [ ] Splitting the Gleevec pill

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

Tammy,

I am on 400mg of Tsigna and the pills are 200mg each. My Dr. told me that I

could take 200 in the am and 200 in the pm if I wanted to. I decided against

it because I had no side effects from it and you have to take it 2 hours

after you eat and then wait another hour before eating. I thought that would

be tougher for me to do so now I get up at 5:30 (I wake at that time every

morning to go to the bathroom anyways) and take them and go back to bed.

So I believe you could do it if you wanted to. I remember when I was on

Gleevec. I used to worry about getting sick all the time and worried if I

ate enough. I took them at night before I went to bed with a snack.

I did not mean to sound like I knew about it all I was just concerned that

you were doing so well so why mess with it but I can now understand where

you are coming from. I did not realize you got sick from the gleevec. It is

a tough one. Your dr. says no yet you know of people who are doing it and

they are fine. I would talk to the dr. again.

Good luck to you.

Sharon t

_____

From: [mailto: ] On Behalf Of Zavie

miller

Sent: Friday, June 06, 2008 10:02 PM

Subject: RE: [ ] Splitting the Gleevec pill

Hi Tammy,

I wouldn't give up so easy. Why not write Dr. Druker and pose the question

to him.

Your doctor's answer doesn't make sense. The half life if Gleevec is 18

hours. What this means is that whether you take 1x400 mg pill daily or 2x200

mg pills daily, the Gleevec level is the same all day.

Zavie

Dr. Druker drukerbohsu (DOT) <mailto:drukerb%40ohsu.edu> edu

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmillersympatico (DOT) <mailto:zmiller%40sympatico.ca> ca

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: June 7, 2008 12:40 AM

groups (DOT) <mailto:%40> com

Subject: RE: [ ] Splitting the Gleevec pill

I don't know... but the doc called back and said no. She wants all the

medicine working at once. Ugh.

My side effects aren't bad. I was just trying to get rid of the nausea when

taking it. At 400mg it isn't too bad if I eat a lot of bread, but I was

trying to cut back.

Oh well.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Zavie

miller

Sent: Saturday, June 07, 2008 12:20 AM

groups (DOT) <mailto:%40> com

Subject: RE: [ ] Splitting the Gleevec pill

Hi Tammy,

That's a remarkable answer. Why would they score the pill if they didn't

want you to take half of it?

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmillersympatico (DOT) <mailto:zmiller%40sympatico.ca> ca

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: June 6, 2008 12:06 PM

groups (DOT) <mailto:%40> com

Subject: RE: [ ] Splitting the Gleevec pill

I called Novartis, and they said we do not recommend unless you doctor

approves it.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: Friday, June 06, 2008 11:58 AM

groups (DOT) <mailto:%40> com

Subject: [ ] Splitting the Gleevec pill

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

You know what I think? I think most doctors get the info on these drugs , read

it, and then go by it, without taking into consideration everything is not that

cut and dried. Everyone is so different. When the drugs are in trial, that is

different strict protocol has to be followed. But when the drug is approved,

they can ease off a bit, and I think the cml experts do, it's the " other "

doctors that may not have the experience to do so.

I was on 800 mg, and split the dose , morning and evening. but I would eat a

little, take a pill, eat a little more, take another pill. But always with a

substantial meal, never anything light.

As far as cutting a scored pill in half, isn't they why they are scored? As

long as the required dose is being taken, I don't know why you can't take it

when and how you want, as long as it works for you. That's my two cents worth,

Bobby

ps - except for right before nap or bed time, then Gleevec can upset the

stomach!!!!

Zavie miller <zmiller@...> wrote:

Hi Tammy,

I wouldn't give up so easy. Why not write Dr. Druker and pose the question

to him.

Your doctor's answer doesn't make sense. The half life if Gleevec is 18

hours. What this means is that whether you take 1x400 mg pill daily or 2x200

mg pills daily, the Gleevec level is the same all day.

Zavie

Dr. Druker drukerb@...

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: [mailto: ] On Behalf Of Tammy

Ferns

Sent: June 7, 2008 12:40 AM

Subject: RE: [ ] Splitting the Gleevec pill

I don't know... but the doc called back and said no. She wants all the

medicine working at once. Ugh.

My side effects aren't bad. I was just trying to get rid of the nausea when

taking it. At 400mg it isn't too bad if I eat a lot of bread, but I was

trying to cut back.

Oh well.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Zavie

miller

Sent: Saturday, June 07, 2008 12:20 AM

groups (DOT) <mailto:%40> com

Subject: RE: [ ] Splitting the Gleevec pill

Hi Tammy,

That's a remarkable answer. Why would they score the pill if they didn't

want you to take half of it?

Zavie

Zavie (age 70)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.5 log reduction Jan/08

3.6 log reduction Apr/08

e-mail: zmillersympatico (DOT) <mailto:zmiller%40sympatico.ca> ca

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

YM: zaviemiller

Skype: Zavie

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: June 6, 2008 12:06 PM

groups (DOT) <mailto:%40> com

Subject: RE: [ ] Splitting the Gleevec pill

I called Novartis, and they said we do not recommend unless you doctor

approves it.

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf Of

Tammy

Ferns

Sent: Friday, June 06, 2008 11:58 AM

groups (DOT) <mailto:%40> com

Subject: [ ] Splitting the Gleevec pill

Can I split a 400 mg Gleevec pill? I'd like to try taking 200 mg at a time

to avoid having to eat a huge bready meal. Thank you,

Tammy

P.S. When I called my onc she said " Go ahead and try that for now, and I'll

research it and if I find any issues I'll call you. "

---I'm not getting a happy feeling.

[Guest guest]

Zavie,

THANKS!!!

I emailed Dr. Druker and here is his response! I'm gonna try it for a

while and see if it works.

We'll see!

Tammy

Re: Splitting the Gleevec Pill

Dear Tammy,

Yes, it is okay to split the pills. I'm told by some patients that the inner

edges have a bitter taste. You can also get 100 mg tablets prescribed and

take two of these twice per day.

Druker, MD

>>> " Tammy Ferns " <tammy@...> 6/7/2008 6:05 AM >>>

Dear Dr. Druker,

First, I'm thankful for your wisdom and ingenuity to create a powerful drug

that has saved my life.

Second, I am trying to find out if it safe to cut the 400mg Gleevec in half

to talk 200 mg in the morning and 200 mg in the evening. I really don't have

many side effects, except that in order to not be very nauseated, I have to

eat a huge meal of mainly bread. To get to the point - I am gaining about

1-2 lbs per week, and I can't seem to stop it. I was hoping to try taking

less Gleevec at a time to not be as nauseated at a time.

Thank you for your time,

Tammy