RE: Sprycel News

[Guest guest]

The dose of 100 mg has to be in the morning to be considered the " best

dose? " I take mine in the evening at bedtime and was wondering if should

switch

the time.....I am also PCRU.

Hugs and Hope-

36

CML 5/13/05

Gleevec 800mg until 8/07

Spyrcel 100 mg since 9/07

Wife and mother of 3 (12,9,7)

# 907 in Zavie's Zero Club

In a message dated 4/9/2008 6:01:20 P.M. Central Daylight Time,

seloew12@... writes:

Hi Everyone,

Some of you may already know this but if you don't here's some news on what

is now considered the best dosage of Sprycel. I had my quarterly check-up

today (all counts excellent and PCRU). I've been on the trial at the University

of loand for more than 2 years and have been PCRU for about a year with

very low counts prior to that.

I take 100 mg once in the morning daily. That is now considered the best

dosage of Sprycel in trials. For those on higher dosages I don't know but for

those at 100 mg or less, the best dosage is 100 mg a day once in the morning.

People on other dosages and those who take their dosage twice a day instead of

once may have their dosages changed on trials because of " safety " issues

according to Bristol Meyers Squibb. They don't say exactly what those issues

are

but I imagine it has to do with side effects such as pleural effusion.

I feel fortunate that I've been on what has now proven out to be the best

overall dosage and the proof lies in the fact that although I had one bout with

pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the

symptoms disappeared.

Cheerfully,

[Non-text portions of this message have been removed]

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[Guest guest]

Thanks Sharon and . The time seems to work so I will not " mess with a

good thing!!! "

Thanks for the input.

In a message dated 4/9/2008 10:46:37 P.M. Central Daylight Time,

onthewtr@... writes:

,

I agree with susan. If it works don't break it. Know what I mean? They told

me I could take my Tasigna 100mg in the morning and 100mg at night. I have

always taken 200mg in the morning and I am doing so well I decided to

continue doing 200mg in the morning.

Sharon

_____

From: _@..._ (mailto: )

[mailto:_@..._ (mailto: ) ] On Behalf Of

seloew12

Sent: Wednesday, April 09, 2008 5:38 PM

_@..._ (mailto: )

Subject: Re: [ ] Sprycel News

Don't know, . If you haven't had side effects and you're PCRU I

personally wouldn't worry about it! You're doing great!

Cheers,

Re: [ ] Sprycel News

The dose of 100 mg has to be in the morning to be considered the " best

dose? " I take mine in the evening at bedtime and was wondering if should

switch

the time.....I am also PCRU.

Hugs and Hope-

36

CML 5/13/05

Gleevec 800mg until 8/07

Spyrcel 100 mg since 9/07

Wife and mother of 3 (12,9,7)

# 907 in Zavie's Zero Club

In a message dated 4/9/2008 6:01:20 P.M. Central Daylight Time,

seloew12cox (DOT) <mailto:seloew12%mailto:se> net writes:

Hi Everyone,

Some of you may already know this but if you don't here's some news on what

is now considered the best dosage of Sprycel. I had my quarterly check-up

today (all counts excellent and PCRU). I've been on the trial at the

University

of loand for more than 2 years and have been PCRU for about a year with

very low counts prior to that.

I take 100 mg once in the morning daily. That is now considered the best

dosage of Sprycel in trials. For those on higher dosages I don't know but

for

those at 100 mg or less, the best dosage is 100 mg a day once in the

morning.

People on other dosages and those who take their dosage twice a day instead

of

once may have their dosages changed on trials because of " safety " issues

according to Bristol Meyers Squibb. They don't say exactly what those issues

are

but I imagine it has to do with side effects such as pleural effusion.

I feel fortunate that I've been on what has now proven out to be the best

overall dosage and the proof lies in the fact that although I had one bout

with

pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the

symptoms disappeared.

Cheerfully,

[Non-text portions of this message have been removed]

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(_http://travel._'>http://travel._ (http://travel./)

<_http://travel.http://travel.http://travelhttp://travehttp://travel.<Whttp_

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aol.com/travel-aol.com/traveaol.com/travaol.com/travel-aol.c

[Non-text portions of this message have been removed]

[Non-text portions of this message have been removed]

[Non-text portions of this message have been removed]

**************Planning your summer road trip? Check out AOL Travel Guides.

(http://travel.aol.com/travel-guide/united-states?ncid=aoltrv00030000000016)

[Guest guest]

Don't know, . If you haven't had side effects and you're PCRU I

personally wouldn't worry about it! You're doing great!

Cheers,

Re: [ ] Sprycel News

The dose of 100 mg has to be in the morning to be considered the " best

dose? " I take mine in the evening at bedtime and was wondering if should

switch

the time.....I am also PCRU.

Hugs and Hope-

36

CML 5/13/05

Gleevec 800mg until 8/07

Spyrcel 100 mg since 9/07

Wife and mother of 3 (12,9,7)

# 907 in Zavie's Zero Club

In a message dated 4/9/2008 6:01:20 P.M. Central Daylight Time,

seloew12@... writes:

Hi Everyone,

Some of you may already know this but if you don't here's some news on what

is now considered the best dosage of Sprycel. I had my quarterly check-up

today (all counts excellent and PCRU). I've been on the trial at the

University

of loand for more than 2 years and have been PCRU for about a year with

very low counts prior to that.

I take 100 mg once in the morning daily. That is now considered the best

dosage of Sprycel in trials. For those on higher dosages I don't know but for

those at 100 mg or less, the best dosage is 100 mg a day once in the morning.

People on other dosages and those who take their dosage twice a day instead of

once may have their dosages changed on trials because of " safety " issues

according to Bristol Meyers Squibb. They don't say exactly what those issues

are

but I imagine it has to do with side effects such as pleural effusion.

I feel fortunate that I've been on what has now proven out to be the best

overall dosage and the proof lies in the fact that although I had one bout

with

pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the

symptoms disappeared.

Cheerfully,

[Guest guest]

,

I agree with susan. If it works don't break it. Know what I mean? They told

me I could take my Tasigna 100mg in the morning and 100mg at night. I have

always taken 200mg in the morning and I am doing so well I decided to

continue doing 200mg in the morning.

Sharon

_____

From: [mailto: ] On Behalf Of

seloew12

Sent: Wednesday, April 09, 2008 5:38 PM

Subject: Re: [ ] Sprycel News

Don't know, . If you haven't had side effects and you're PCRU I

personally wouldn't worry about it! You're doing great!

Cheers,

Re: [ ] Sprycel News

The dose of 100 mg has to be in the morning to be considered the " best

dose? " I take mine in the evening at bedtime and was wondering if should

switch

the time.....I am also PCRU.

Hugs and Hope-

36

CML 5/13/05

Gleevec 800mg until 8/07

Spyrcel 100 mg since 9/07

Wife and mother of 3 (12,9,7)

# 907 in Zavie's Zero Club

In a message dated 4/9/2008 6:01:20 P.M. Central Daylight Time,

seloew12cox (DOT) <mailto:seloew12%40cox.net> net writes:

Hi Everyone,

Some of you may already know this but if you don't here's some news on what

is now considered the best dosage of Sprycel. I had my quarterly check-up

today (all counts excellent and PCRU). I've been on the trial at the

University

of loand for more than 2 years and have been PCRU for about a year with

very low counts prior to that.

I take 100 mg once in the morning daily. That is now considered the best

dosage of Sprycel in trials. For those on higher dosages I don't know but

for

those at 100 mg or less, the best dosage is 100 mg a day once in the

morning.

People on other dosages and those who take their dosage twice a day instead

of

once may have their dosages changed on trials because of " safety " issues

according to Bristol Meyers Squibb. They don't say exactly what those issues

are

but I imagine it has to do with side effects such as pleural effusion.

I feel fortunate that I've been on what has now proven out to be the best

overall dosage and the proof lies in the fact that although I had one bout

with

pleural effusion and peripheral neuropathy, 2 1/2 weeks off Sprycel and the

symptoms disappeared.

Cheerfully,