Alpha Lipoic Acid and rash

January 11, 2006

Hi

I went back and was reading some old posts and found that people were

discussing ALA and that it was helping them. I break out with severe

itchy bumpy red rash all over my body even if I take a TINY amount

(like 1mg) of ALA. Does anyone know why this could be happening ? No,

I do NOT have such a reaction with ANYTHING else at all. I honestly do

not think it could be the mercury as the reaction seems to be

immediate like an allergic reaction. But why only to ALA and it

doesn't happen with any other sulphur supplement either.

Thanks for any thoughts

Jay

January 11, 2006

There are still a lot of questions about this. For one thing, most places sell

ALA. R-Lipoic Acid is what the original research was done with, and even the

original researcher disclaims general use as the research done was very limited.

There is some suspicion that ALA, besides not being helpful, can be downright

harmful. Rustoleum is a fabulous anti-oxidant, too. But you wouldn't eat the

stuff. I don't have the link any more, but you could google it. (I can't take

either type. The stomach acidity is just too much to deal with. Once I found the

research on it, I really didn't care about it any more.)

jkrishnaa <jkrishnaa@...> wrote: Hi

I went back and was reading some old posts and found that people were

discussing ALA and that it was helping them. I break out with severe

itchy bumpy red rash all over my body even if I take a TINY amount

(like 1mg) of ALA. Does anyone know why this could be happening ? No,

I do NOT have such a reaction with ANYTHING else at all. I honestly do

not think it could be the mercury as the reaction seems to be

immediate like an allergic reaction. But why only to ALA and it

doesn't happen with any other sulphur supplement either.

Thanks for any thoughts

Jay

FAIR USE NOTICE:

January 11, 2006

Wow, Serena. I didn't know about this.

Thanks

Jay

SERENA EDWARDS <pushcrash@...> wrote:

There are still a lot of questions about this. For one thing, most places sell

ALA. R-Lipoic Acid is what the original research was done with, and even the

original researcher disclaims general use as the research done was very limited.

There is some suspicion that ALA, besides not being helpful, can be downright

harmful. Rustoleum is a fabulous anti-oxidant, too. But you wouldn't eat the

stuff. I don't have the link any more, but you could google it. (I can't take

either type. The stomach acidity is just too much to deal with. Once I found the

research on it, I really didn't care about it any more.)

jkrishnaa <jkrishnaa@...> wrote: Hi

I went back and was reading some old posts and found that people were

discussing ALA and that it was helping them. I break out with severe

itchy bumpy red rash all over my body even if I take a TINY amount

(like 1mg) of ALA. Does anyone know why this could be happening ? No,

I do NOT have such a reaction with ANYTHING else at all. I honestly do

not think it could be the mercury as the reaction seems to be

immediate like an allergic reaction. But why only to ALA and it

doesn't happen with any other sulphur supplement either.

Thanks for any thoughts

Jay

FAIR USE NOTICE:

January 11, 2006

Me, either, until then. There might actually be some benefits in there

somewhere, but I couldn't find any further studies or anything to support it,

and the original was just a rat study (Oh, where I heard THAT one before?).

What I did find, was that the idea got picked up, a couple of very enthuiastic

articles came out, and the product was suddenly all over the place - in a form

other than the one the study was about. People still swear by it - but they

always seem to be the same people who slug down fistfuls of other supplements,

so then I always wonder how they could possibly tell what was affecting their

sense of well-being and what was not. Even the first popular articles didn't

claim that ALA would make anyone feel instantly fabulous. Sheer enthusiasm,

otoh, can make you feel pretty groovy. It might even have some strong antoxident

properties, but I'm fresh out of rats ( a little mold-related research joke,

there : )

I'm keeping a good thought on your baby boy. I hope he regains his health

soon.

Serena

There is no such thing as an anomaly. Recheck your original premise.

...Ayn Rand,

paraphrased

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January 11, 2006

Hi

I have used ALA at very low doses with my son (per Andy Cutler protocol) and

he did extremely well initially but started to develop fears, photophobia etc

(though he was on biotin supp too at that time). Even now, initially he does

very well on it but starts to react slowly.

For me, it was the rash reaction. So, if you have any ideas on why this

reaction, I would really appreciate it. I don't usually have allergic reaction

like this to anything at all. And no doctor so far has been helpful in figuring

this out.

Thanks

Jay

LiveSimply <quackadillian@...> wrote:

You guys are too much. Well, suit yourselves, its your life..

BTW, every indication I have seen and literally 70 or 80 studies show

ALA (yes, especially the R isomer, but also the racemic ALA you find

at a much lower markup in stores) as helping dramatically improve your

body's ability to fight reactive oxygen species - induced cell damage.

This seems to me to be a no-brainer.. (VERY MUCH WORTH SOME STOMACH

DISCOMFORT..)

I GOT THE FOLLOWING FROM A PDF OF ABSTRACTS ON ALA FOUND ON ANOTHER

WEBSITE.. (I did not check the following information. I DO NOT HAVE AN

AGENDA...)

I am not a Scientologist.. also... I chew all cults very well and

prefer not to swallow them...

____BEGIN QUOTED TEXT_________

ALPHA LIPOIC ACID

70 ABSTRACTS

PubMed search of:

Alpha-lipoic acid, therapeutic = 380 hits

Alpha-lipoic acid, deficiency = 50 hits

Alpha-lipoic acid, human = 510 hits

Alpha-lipoic acid, animal = 673 hits

MESH search of:

Alpha-lipoic acid, therapeutic = 320 hits

Alpha-lipoic acid, deficiency = 2 hits

____MORE QUOTED TEXT_________

Alpha lipoic acid Overview

Alpha lipoic acid is an enzyme found in the mitochondria – the energy

producing structures found inside each cell. As a dietary supplement,

alpha-lipoic acid may act as a powerful antioxidant. Its action is

enhanced by other nutrient antioxidants like vitamins C and E.

The body under optimum conditions may be able to manufacture enough

alpha-lipoic acid for its metabolic functions (as a co-factor for a

number of enzymes involved in converting fat and sugar to energy), but

additional amounts provided by supplements allow alpha-lipoic acid to

circulate in a " free " state. In this state, alpha-lipoic acid has the

unique ability to function as both a water- and fat-soluble

antioxidant. Most antioxidants are effective in only one area or the

other. Vitamin C is usually restricted to the interior compartment of

cells and the watery portion of blood, while vitamin E works at the

lipid level of cell membranes. Also important is its role in the

production of glutathione, one of the chief antioxidants produced

directly by the body.

____MORE QUOTED TEXT_________

Dosage: Average dosage, 50-100 mg per day.

Side Effects: Alpha lipoic acid appears to be safe as a dietary

supplement. Intakes of as much as 600 mg per day have been used for

treatment of diabetic neuropathy, with no serious side effects.

(Source: www.supplementwatch.com)

Research Overview

1. Improves several indices of metabolic activity

2. Lowers the degree of oxidative stress

3. Reverses the declines in oxygen consumption and mitochondrial

energy production that are commonly observed with aging

4. Enhances mitochondrial energy levels

25. Elevates levels of glutathione and ascorbic acid suggesting that

it helps protect and/or recycle these antioxidants and contributes to

the overall capacity of the body to neutralize free radical damage

6. May be helpful in patients with diabetes

a. Promotes the production of energy from fat and sugar in the mitochondria

b. Enhances removal of glucose from the bloodstream

c. Decreases insulin resistance

d. Treats peripheral neuropathy associated with diabetes.

e. The American Diabetes Association has suggested that alpha-lipoic

acid plus vitamin E may be helpful in combating some of the health

complications associated with diabetes, including heart disease,

vision problems, nerve damage and kidney disease.

7. May help to protect the brain from damage following a stroke.

8. Prevents cellular damage (from free radicals)

9. Reduces oxidative stress

____ENDING QUOTED TEXT FROM FOUND PDF - IN WHICH THERE ARE ROUGHLY 70

PAGES MORE_________

On 1/11/06, SERENA EDWARDS

wrote:

> Me, either, until then. There might actually be some benefits in there

somewhere, but I couldn't find any further studies or anything to support it,

and the original was just a rat study (Oh, where I heard THAT one before?). What

I did find, was that the idea got picked up, a couple of very enthuiastic