Re: Sprycel Side Effects

[Guest guest]

Hi Mandy--

My husband has been on Sprycel for about 6 months. First couple weeks were a

little odd with strange rashes, some swelling around the eyes, fatigue and some

headaches. I say " odd " only because sometimes we would be talking, I'd go to the

bathroom really quick and come back and all of the sudden his entire neck would

be rashed! So the side affects literally could come out of the blue and last for

an hour or longer and then go away as fast as they came on. But all in all his

experience on Sprycel has been way better than on Gleevec. In fact, I think his

favorite thing is the fact that on Sprycel he can take it with or without food

and it is fine either way (I think they recommend taking it with food, I am just

stating what 's experience has been!. On Gleevec, he had to gourge himself

before taking it and most days he would still get extreme fatigue for about an

hour or two after taking it, not to mention a very upset stomach.

All in all other than what I have mentioned above, he has been pretty " normal "

on Sprycel. He is at the higher 140mg doseage (taken twice a day), and has

pretty much no side affects. Well, he does require more sleep than he used

to--at least 8-9 hours per night, but other than that is doing very well. Our

" new life " involves earlier bed times, less drinking, less physical activity

like snowboarding or working all day in our yard, but we always wonder if that

is due to our getting older and the fact that we now have a 1 1/2 year old!

Those little guys should come with some warning labels: toddlers may cause:

severe fatigue, headaches, muscle pain (from picking them up all the time!),

upset stomach (from the nasty diapers they have!), and the list goes on!!

My husband went off Gleevec due to liver toxicity...may I ask why your husband

is switching?

Good luck to you guys--dont hesitate to write to us offline if you have any

further questions at: weez_555@....

Good luck!

Cervera

(wife of Cervera, CML since 07/2006, currently on 140mg Sprycel daily)

@...: bledsoewedding@...: Wed, 26 Dec 2007

03:12:04 +0000Subject: [ ] Sprycel side effects

Hey all!My husband (CML) has just been switched from Gleevec to Sprycel in the

last week. We're trying to get a good idea what types of side effects he can

expect. The documentation never seems to be 100% accurate, so we like to get a

little bit of feedback from people already on it.Thanks in advance for all of

the help that you are able to provide!Mandy

_________________________________________________________________

Don't get caught with egg on your face. Play Chicktionary!

http://club.live.com/chicktionary.aspx?icid=chick_wlhmtextlink1_dec

[Guest guest]

Hi,

First of all I wish you well, My experience is the that I had severe migraines

for about 3 weeks. Some soft stool, but that was it. I took tramadol 100mg for

the migraines, since tylenol and advil, aleve were all contraindicated by the

doc. Well good luck on your journey.

Mel

-------------- Original message from " " <bledsoewedding@...>:

--------------

Hey all!

My husband (CML) has just been switched from Gleevec to Sprycel in the

last week. We're trying to get a good idea what types of side effects

he can expect. The documentation never seems to be 100% accurate, so

we like to get a little bit of feedback from people already on it.

Thanks in advance for all of the help that you are able to provide!

Mandy

[Guest guest]

Hi Mandy,or the first 1 1/2 years I didn't have any side effects at all. Now,

for the last 3 weeks, a.\ll 10 finger tips are numb. It's getting better but

still there. Minor compared to what it could be, don't you think?

Susa L

[ ] Sprycel side effects

Hey all!

My husband (CML) has just been switched from Gleevec to Sprycel in the

last week. We're trying to get a good idea what types of side effects

he can expect. The documentation never seems to be 100% accurate, so

we like to get a little bit of feedback from people already on it.

Thanks in advance for all of the help that you are able to provide!

Mandy

[Guest guest]

I've mentioned this before---I had a serious reaction to Sprycel which affects a

very small percentage. It was shortness of breath followed by pulmonary edema

that sent me to the ER and ICU. It came on quite suddenly and was so severe that

I had no doubt that I needed to get to the hospital. I'm back on Gleevec (400mg)

and am doing better on a reduced maintance dose and have milder side effects.

Good luck. I hope Sprycel works better for others. It sure would be nice not

to have a puffy face and weight gain.

Margaret

Loewenkamp <loewen1@...> wrote:

Hi Mandy,or the first 1 1/2 years I didn't have any side effects at

all. Now, for the last 3 weeks, a.\ll 10 finger tips are numb. It's getting

better but still there. Minor compared to what it could be, don't you think?

Susa L

[ ] Sprycel side effects

Hey all!

My husband (CML) has just been switched from Gleevec to Sprycel in the

last week. We're trying to get a good idea what types of side effects

he can expect. The documentation never seems to be 100% accurate, so

we like to get a little bit of feedback from people already on it.

Thanks in advance for all of the help that you are able to provide!

Mandy

[Guest guest]

Thanks to all who have already responded. DH was on 600mg Gleevec

since diagnosis in 2/07, but stopped responding to Gleevec in the

last month and moved into a blast crisis. The doctor tested his

Gleevec level (thanks to a free test from Novartis) and said there

was plenty of medicine floating around in there, but his CML was

resisting it. Which is really too bad because he had very minimal

side effects on the drug and was able to work and exercise.

We are adjusting to the Sprycel and likelihood of a transplant. It's

a lot to wrap our heads around, but I'm sure we'll get there. DH has

mentioned a very itchy head several times and worries about hair loss

with the new meds. He's also gotten rash like symptoms -- bumpy

skin, although not really itchy.

He's only been on Sprycel about a week, but it's so much nicer to be

educated about potential symptoms so that we are reassured if we see

them.

Thanks again for your feedback!

Mandy

[Guest guest]

Yes--scratchy head..forgot to mention that one. Yep-- had that, too...lasted

about 2-3 weeks then went away.

Good luck on your CML journey, hope Sprycel gives him more success than Gleevec.

@...: bledsoewedding@...: Wed, 26 Dec 2007

23:33:06 +0000Subject: Re: [ ] Sprycel side effects

Thanks to all who have already responded. DH was on 600mg Gleevec since

diagnosis in 2/07, but stopped responding to Gleevec in the last month and moved

into a blast crisis. The doctor tested his Gleevec level (thanks to a free test

from Novartis) and said there was plenty of medicine floating around in there,

but his CML was resisting it. Which is really too bad because he had very

minimal side effects on the drug and was able to work and exercise.We are

adjusting to the Sprycel and likelihood of a transplant. It's a lot to wrap our

heads around, but I'm sure we'll get there. DH has mentioned a very itchy head

several times and worries about hair loss with the new meds. He's also gotten

rash like symptoms -- bumpy skin, although not really itchy.He's only been on

Sprycel about a week, but it's so much nicer to be educated about potential

symptoms so that we are reassured if we see them.Thanks again for your

feedback!Mandy

_________________________________________________________________

The best games are on Xbox 360. Click here for a special offer on an Xbox 360

Console.

http://www.xbox.com/en-US/hardware/wheretobuy/

[Guest guest]

my daughter is on sprycel and the doctor told her she can take tylenol extra

stringth, I would like to know who told you MEl that tylenol were not good with

this pills, she have been taking tylenol like crazy , because of headach,

please let me know more info, im very nervous about this, i woudent want some

more bad reaction to her meds , she had a ruff time with gleevec, and she just

started on sprycel, and i woudent want some thing els to go wrong, please let me

know , so i can educate miself and her , thanks

http://asksantaclaus.spaces.live.com/

[Guest guest]

I had severe headaches (burning worst than a migraine if possible) almost from

beginning. Lasting anywhere from 3 seconds to 5 minutes and somtimes continue

for a couple of hours and then went away eventually, havent had one months.

Joint pain fatigue. If you really excert yourself the muscles burn almost scream

at you. But all is something you can live with. I have been on Sprycel since

April to now.

God Bless you Happy New Year

[ ] Sprycel side effects

Hey all!

My husband (CML) has just been switched from Gleevec to Sprycel in the

last week. We're trying to get a good idea what types of side effects

he can expect. The documentation never seems to be 100% accurate, so

we like to get a little bit of feedback from people already on it.

Thanks in advance for all of the help that you are able to provide!

Mandy

________________________________________________________________________________\

____

Looking for last minute shopping deals?

Find them fast with Search.

http://tools.search./newsearch/category.php?category=shopping

[Guest guest]

I had some hair loss but not real bad, but has stopped and is coming back, yes I

too have the numbness in my fingers and toes but not as often as it was. Dry

skin has become the major problem now. And red, itchy splotches on my face, but

am waiting for it to go away as the other things have with time. I drink almost

a gallon of water a day that keeps the stomach cramps to a minimum. But not

every one has the same side effects. Still much better than the experiences of

Gleevic.

God Bless , Anita

Re: [ ] Sprycel side effects

Thanks to all who have already responded. DH was on 600mg Gleevec

since diagnosis in 2/07, but stopped responding to Gleevec in the

last month and moved into a blast crisis. The doctor tested his

Gleevec level (thanks to a free test from Novartis) and said there

was plenty of medicine floating around in there, but his CML was

resisting it. Which is really too bad because he had very minimal

side effects on the drug and was able to work and exercise.

We are adjusting to the Sprycel and likelihood of a transplant. It's

a lot to wrap our heads around, but I'm sure we'll get there. DH has

mentioned a very itchy head several times and worries about hair loss

with the new meds. He's also gotten rash like symptoms -- bumpy

skin, although not really itchy.

He's only been on Sprycel about a week, but it's so much nicer to be

educated about potential symptoms so that we are reassured if we see

them.

Thanks again for your feedback!

Mandy

________________________________________________________________________________\

____

Never miss a thing. Make your home page.

http://www./r/hs

[Guest guest]

>

>

> my daughter is on sprycel and the doctor told her she can take

tylenol extra stringth, I would like to know who told you MEl that

tylenol were not good with this pills, she have been taking tylenol

like crazy , because of headach, please let me know more info, im

very nervous about this, i woudent want some more bad reaction to her

meds , she had a ruff time with gleevec, and she just started on

sprycel, and i woudent want some thing els to go wrong, please let me

know , so i can educate miself and her , thanks

> http://asksantaclaus.spaces.live.com/

>

>

[Guest guest]

I thought that it was a no-no to take tyleonol while on Gleevec because of the

fact that Gleevec is processed by the liver, and so is Tyleonol and the thinking

was that one should not overload the liver. My husband had to go off Gleevec due

to liver toxicity, and so when he switched to Sprycel there was alot of talk

(with his oncologist and Dr. Druker), about how most likely he would NOT have

the same liver issues on Sprycel because it is not processed by the liver. So,

because Sprycel is not hard on the liver, it makes sense that one could take

Tylenol. BUT--yes--conflicting opinions...and this is just MY thinking on the

issue--so take it with a grain of salt I guess.

@...: no_reply@...: Thu, 27 Dec 2007

14:22:02 +0000Subject: [ ] Re: Sprycel side effects

>> > my daughter

is on sprycel and the doctor told her she can take tylenol extra stringth, I

would like to know who told you MEl that tylenol were not good with this pills,

she have been taking tylenol like crazy , because of headach, please let me know

more info, im very nervous about this, i woudent want some more bad reaction to

her meds , she had a ruff time with gleevec, and she just started on sprycel,

and i woudent want some thing els to go wrong, please let me know , so i can

educate miself and her , thanks > http://asksantaclaus.spaces.live.com/> >

[Guest guest]

I was told by my Onc and also by the lead trail specialist at MDACC orlando. It

has a liver effect, and so does any tyrosine kinase inhibitor, so they said no,

no.

That is my experience.

Mel

-------------- Original message from jeanny forest <jeanny-f@...>:

--------------

my daughter is on sprycel and the doctor told her she can take tylenol extra

stringth, I would like to know who told you MEl that tylenol were not good with

this pills, she have been taking tylenol like crazy , because of headach, please

let me know more info, im very nervous about this, i woudent want some more bad

reaction to her meds , she had a ruff time with gleevec, and she just started on

sprycel, and i woudent want some thing els to go wrong, please let me know , so

i can educate miself and her , thanks

http://asksantaclaus.spaces.live.com/

[Guest guest]

It may depend on each case. I am on gleevec (400mg, since 2005), my

liver numbers were never abnormal and my hemato let me take tylenol,

in moderation. I don't need it often. When I have a cold I take 1 or 2

daily pills of sudafed. Some tylenol also when I get some joint pain

after climbing (maybe some damage from when my wbc was sky high, or

just getting older). I alternate with aspirin or ibuprophen when

necessary (what happened only once and for just 2/3 h since 2005).

Happy new year everybody,

Marcos.

On Dec 27, 2007 1:46 PM, <g8trdoc81@...> wrote:

>

>

> I was told by my Onc and also by the lead trail specialist at MDACC orlando.

It has a liver effect, and so does any tyrosine kinase inhibitor, so they said

no, no.

>

> That is my experience.

> Mel

>

> -------------- Original message from jeanny forest <jeanny-f@...>:

--------------

>

>

> my daughter is on sprycel and the doctor told her she can take tylenol extra

stringth, I would like to know who told you MEl that tylenol were not good with

this pills, she have been taking tylenol like crazy , because of headach, please

let me know more info, im very nervous about this, i woudent want some more bad

reaction to her meds , she had a ruff time with gleevec, and she just started on

sprycel, and i woudent want some thing els to go wrong, please let me know , so

i can educate miself and her , thanks

> http://asksantaclaus.spaces.live.com/

>

>

[Guest guest]

if she cant take tylenol what should she take with sprycel, help me out every

body, it havent been that long that sprycel is on the market, so i dont beleive

doctors to much, because some say to take only tylenol then you go see another

doctor and he say, dont take tylenol, did any one have experience on this,

http://asksantaclaus.spaces.live.com/

[Guest guest]

,

I was given Tramadol 100mg for the bad times, and 50 mg for the so so times. If

her platlets are low it goes without saying no aspirin.

Mel

-------------- Original message from jeanny forest <jeanny-f@...>:

--------------

if she cant take tylenol what should she take with sprycel, help me out every

body, it havent been that long that sprycel is on the market, so i dont beleive

doctors to much, because some say to take only tylenol then you go see another

doctor and he say, dont take tylenol, did any one have experience on this,

http://asksantaclaus.spaces.live.com/

[Guest guest]

>

> I have been on Sprycel since Thanksgiving and have had many strange

> side effects, but one I'm really having trouble dealing with is the

> amount of weight I have gained in such a short time. Has anyone else

> experienced this? I'm not a junk food junkie and I don't sit around

> all the time, unless I'm in a lot of pain,most of the time I'm quite

> active. I just can't believe that this much weight gain is normal

> unless the medication is causing it. I was given lasix 40 mg for

> fluid retention but it does not help much. Please tell me I'm not the

> only one experiencing this.

>

> Thanks!

> LB

>

Did your doctor see something on your exams that made them think you

were retaining fluid and hence the need for Lasix?

The prescribing information for Sprycel lists that 11% of people taking

the drug reported some weight gain. 1% reported a gain of more than

20% of their baseline weight before swithcing to Sprycel.

What dose of Sprycel did your Oncologist put you on?

[Guest guest]

Matt,

Sorry to hear about the loss of PCRU...I switched from Gleevec to sprycel a

couple months ago..I had some headaches,fatigue,severe bone/joint/muscle pains

and spasms and severe constipation..Oh yeah..the big ol weight gain too..The

typical stuff I think..Doesn't seem to matter which med I take I have the same

damn side effects..lol..Just the way it is I suppose..I hope your transition

goes smoothly and regain PCRU..I check in two more weeks to see if I am

regaining my old levels before the switch..

Good Luck.

SharonS

In , mtmaynor@... wrote:

>

> To make a very long story short, I have lost my PCRU while

> on Tasigna, and I am moving to Sprycel on Saturday of this

> week. Can anyone give me some ideas of what to expect

> and anything that has relieved the side effects and adjustment

> period that you seem to always have to go through.

>

> Matt

> Florida

>

>

>

>

[Guest guest]

Matt, please tell me there's more to the story than just losing your PCRU status

and please tell me that a clinical decision wasn't based on one single blood

test, more importantly, a test that wasn't even done in your regular lab.

You know that most of the experts don't believe PCRU should be a goal of

treatment right? A good stable response is what is hoped for by the top

experts.

I've gone in and out of PCRU more times than I can count. What matters is that

I remain stable within a one log range, not if a test is negative or positive.

In fact, to be honest, whenever I get a PCRU result I wonder if they screwed

something up. We all know that these drugs don't cure us and we know that we'll

always have cancer cells lingering around therefore, it's not comforting to me

to see a test that doesn't show any cells, it makes me think they didn't use

enough blood or run the sample long enough.

I've just seen too many examples of tests that bounced around to be concerned.

Unless there's a dramatic increase and by dramatic I mean OVER a log increase in

two or even three consecutive tests, I personally wouldn't make any therapeutic

changes.

Tracey

>

> To make a very long story short, I have lost my PCRU while

> on Tasigna, and I am moving to Sprycel on Saturday of this

> week. Can anyone give me some ideas of what to expect

> and anything that has relieved the side effects and adjustment

> period that you seem to always have to go through.

>

> Matt

> Florida

>

>

>

>

[Guest guest]

Hi again,

Sprycel can also cause Pleural Effusion and that can kill you.

Zavie

Zavie (age 71)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 613-482-4801

Cell: 613-282-0204

ID: zaviem

_____

From: [mailto: ] On Behalf Of

mtmaynor@...

Sent: September 17, 2009 8:50 PM

Subject: Re: [ ] Re: Sprycel Side Effects

Thank you, that is helpful. I thought Sprycel gave you

the " runs " .

Sent from my iPhone

On Sep 17, 2009, at 8:18 PM, " Serenity " <serenitywon@

<mailto:serenitywon%40> > wrote:

> Matt,

> Sorry to hear about the loss of PCRU...I switched from Gleevec to

> sprycel a couple months ago..I had some headaches,fatigue,severe

> bone/joint/muscle pains and spasms and severe constipation..Oh

> yeah..the big ol weight gain too..The typical stuff I think..Doesn't

> seem to matter which med I take I have the same damn side

> effects..lol..Just the way it is I suppose..I hope your transition

> goes smoothly and regain PCRU..I check in two more weeks to see if I

> am regaining my old levels before the switch..

> Good Luck.

> SharonS

>

> In groups (DOT) <mailto:%40> com, mtmaynor@...

wrote:

> >

> > To make a very long story short, I have lost my PCRU while

> > on Tasigna, and I am moving to Sprycel on Saturday of this

> > week. Can anyone give me some ideas of what to expect

> > and anything that has relieved the side effects and adjustment

> > period that you seem to always have to go through.

> >

> > Matt

> > Florida

> >

> >

> >

> >

[Guest guest]

Zavie,

I don't have that one(not yet anyways).Sure hope it is not something I do get

either..My DR does listen to my lungs at every visit.I have some shortness of

breath but I also have leaky heart valves and was told I would eventualy need to

be on oxygen..I'm hope not at 41 but maybe 81..lolI've only been on it for about

2 months now..Strugglin with losing the nearly 20 pounds in abouta month..Slowly

going down if I cut out all extras and count my calories closely..Hope it levels

off and then starts dropping..

Thanks

SharonS

In , " Zavie " <zmiller@...> wrote:

>

> Hi again,

>

> Sprycel can also cause Pleural Effusion and that can kill you.

>

> Zavie

>

> Zavie (age 71)

> 67 Shoreham Avenue

> Ottawa, Canada, K2G 3X3

> dxd AUG/99

> INF OCT/99 to FEB/00, CHF

> No meds FEB/00 to JAN/01

> Gleevec since MAR/27/01 (400 mg)

> CCR SEP/01. #102 in Zero Club

> 2.8 log reduction Sep/05

> 3.0 log reduction Jan/06

> 2.9 log reduction Feb/07

> 3.6 log reduction Apr/08

> 3.6 log reduction Sep/08

> 3.7 log reduction Jan/09

> 3.8 log reduction May/09

> 3.8 log reduction Aug/09

> e-mail: zmiller@...

> Tel: 613-726-1117

> Fax: 613-482-4801

> Cell: 613-282-0204

> ID: zaviem

>

[Guest guest]

My post wasn't clear..I gained nearly 20 pounds in the first month..Trying to

get that weight gain off..

SharonS

In , " Serenity " <serenitywon@...> wrote:

>

> Zavie,

> I don't have that one(not yet anyways).Sure hope it is not something I do

get either..My DR does listen to my lungs at every visit.I have some shortness

of breath but I also have leaky heart valves and was told I would eventualy need

to be on oxygen..I'm hope not at 41 but maybe 81..lolI've only been on it for

about 2 months now..Strugglin with losing the nearly 20 pounds in abouta

month..Slowly going down if I cut out all extras and count my calories

closely..Hope it levels off and then starts dropping..

> Thanks

> SharonS

>

>

> In , " Zavie " <zmiller@> wrote:

> >

> > Hi again,

> >

> > Sprycel can also cause Pleural Effusion and that can kill you.

> >

> > Zavie

> >

> > Zavie (age 71)

> > 67 Shoreham Avenue

> > Ottawa, Canada, K2G 3X3

> > dxd AUG/99

> > INF OCT/99 to FEB/00, CHF

> > No meds FEB/00 to JAN/01

> > Gleevec since MAR/27/01 (400 mg)

> > CCR SEP/01. #102 in Zero Club

> > 2.8 log reduction Sep/05

> > 3.0 log reduction Jan/06

> > 2.9 log reduction Feb/07

> > 3.6 log reduction Apr/08

> > 3.6 log reduction Sep/08

> > 3.7 log reduction Jan/09

> > 3.8 log reduction May/09

> > 3.8 log reduction Aug/09

> > e-mail: zmiller@

> > Tel: 613-726-1117

> > Fax: 613-482-4801

> > Cell: 613-282-0204

> > ID: zaviem

> >

>

[Guest guest]

Hi Sharon, last year on the xl228 drug I had severe constipation,  Nothing

seemed to help.

I discovered Kellogg's All Bran Bran Buds, They have 13 grams of fiber in 1/3

cup/  I don't like milk, but do like whipped yogurt, and that is my breakfast,

every day, I sprinkle the buds on the yogurt.  I also have it for snack in the

evening. And even though it is a bit high in calories, it " does the trick. "  

Ever listen to Dr. Oz on Oprah?  This is his terminology, not mine, but you

should " poop an " S " , every day.  I guarantee, if you eat these little all bran

buds, 1/3 twice a day, or 2/3 once a day, you will not have any problems.  Try

it, and I hope it works for you.  Bobby

a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec

Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra

Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840  -   Zavie's

Zero Club 09/2006 -  out of CCR 04/29/08 - XL228 Trial/ U.of Michigan

06/02/08 - CCR ( in 4 weeks)

02/13/09 - XL trial ended due to side effects

04/13/09 - New Trial, Ariad / U. of Mich./ Dr. Talpaz

 

> > >

> > > To make a very long story short, I have lost my PCRU while

> > > on Tasigna, and I am moving to Sprycel on Saturday of this

> > > week. Can anyone give me some ideas of what to expect

> > > and anything that has relieved the side effects and adjustment

> > > period that you seem to always have to go through.

> > >

> > > Matt

> > > Florida

> > >

> > >

> > >

> > >

[Guest guest]

Sharon, sorry, I forgot to add, just to be sure, I also take a dose of Metamucil

every day.  I am going to stop the Metamucil, and see if just the Bran buds

work, no sense spending extra money if one doesn't have to!  Bobby

a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec

Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra

Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840  -   Zavie's

Zero Club 09/2006 -  out of CCR 04/29/08 - XL228 Trial/ U.of Michigan

06/02/08 - CCR ( in 4 weeks)

09/08/09 - PCR 0.017

02/13/09 - XL trial ended due to side effects

04/13/09 - New Trial, Ariad / U. of Mich./ Dr. Talpaz

 

> > >

> > > To make a very long story short, I have lost my PCRU while

> > > on Tasigna, and I am moving to Sprycel on Saturday of this

> > > week. Can anyone give me some ideas of what to expect

> > > and anything that has relieved the side effects and adjustment

> > > period that you seem to always have to go through.

> > >

> > > Matt

> > > Florida

> > >

> > >

> > >

> > >

[Guest guest]

Bobby,

I am lactose intolerant so no dairy for me..I do have the All Bran Buds and

have used them but I don't eat them every single day..It hasn't helped me but I

will try them daily for a bit and see if that helps..I have had this issue for

10 years and tried just about everything everyone has ever suggested..Fact is I

have a very slow transit time..Takes days to move through..Maybe because I have

had WLS and my intestines have been cut and altered who knows..I will try it

daily and see if it helps..I can't take metamucil as it swells.I do use

benefiber as it doesn't swell and mirilax daily..Swelling is not good for those

who have had RNY surgery.Thanks

SharonS

In , ROBERTA DOYLE <rcd1929@...> wrote:

>

> Sharon, sorry, I forgot to add, just to be sure, I also take a dose of

Metamucil every day.  I am going to stop the Metamucil, and see if just the Bran

buds work, no sense spending extra money if one doesn't have to!  Bobby

>

> a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec

Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra

Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840  -   Zavie's

Zero Club 09/2006 -  out of CCR 04/29/08 - XL228 Trial/ U.of Michigan

06/02/08 - CCR ( in 4 weeks)

> 09/08/09 - PCR 0.017

> 02/13/09 - XL trial ended due to side effects

> 04/13/09 - New Trial, Ariad / U. of Mich./ Dr. Talpaz

>  

>

>

>

>

>

> > > >

>

>

>

> > > > To make a very long story short, I have lost my PCRU while

>

>

>

> > > > on Tasigna, and I am moving to Sprycel on Saturday of this

>

>

>

> > > > week. Can anyone give me some ideas of what to expect

>

>

>

> > > > and anything that has relieved the side effects and adjustment

>

>

>

> > > > period that you seem to always have to go through.

>

>

>

> > > >

>

>

>

> > > > Matt

>

>

>

> > > > Florida

>

>

>

> > > >

>

>

>

> > > >

>

>

>

> > > >

>

>

>

> > > >

[Guest guest]

As far as the buds go, you can mix them with another cereal, and take them with

Silk, which is made of soy, right? I don't because I don't want to take the

milk, and can't even think of eating soyl..  But you must take them faithfully,

every day, to get 26 grams of fiber, and also drink lots of water.  By the way,

if you buy Miralax at Sam's club, you can buy two large ones for the price of

less than one at Walgreen's, just in case you didn't know, I think I paid under

10 for two large.  Always something, right?  Bobby

a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec

Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra

Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840  -   Zavie's

Zero Club 09/2006 -  out of CCR 04/29/08 - XL228 Trial/ U.of Michigan

06/02/08 - CCR ( in 4 weeks)

09/08/09 - PCR 0.017

02/13/09 - XL trial ended due to side effects

04/13/09 - New Trial, Ariad / U. of Mich./ Dr. Talpaz

 

>

>

>

> > > >

>

>

>

> > > > To make a very long story short, I have lost my PCRU while

>

>

>

> > > > on Tasigna, and I am moving to Sprycel on Saturday of this

>

>

>

> > > > week. Can anyone give me some ideas of what to expect

>

>

>

> > > > and anything that has relieved the side effects and adjustment

>

>

>

> > > > period that you seem to always have to go through.

>

>

>

> > > >

>

>

>

> > > > Matt

>

>

>

> > > > Florida

>

>

>

> > > >

>

>

>

> > > >

>

>

>

> > > >

>

>

>

> > > >