Re: Interpretation of PCR Analysis

[Guest guest]

Hi Barbara,

It looks like the Gleevec is working great! It's hard to compare PCR

values because every lab uses independent methods to do the test but

generally speaking, anything that's as far as the third decimal point

is a GREAT result. You'll have to find out the lab's baseline before

you can be sure but from the surface, I think you should celebrate.

Congratulations,

Tracey

>

> I haven't seen my doctor yet, but did get a copy of my latest PCR

Analysis.

> Wondered if someone could confirm the analysis for me. I'm anxious

to know

> if the Gleevec is working. I've been on 400mg since diagnosed July

06.

>

>

>

> Results: Positive Major breakpoint (0.006%)

>

> Interpretation=this result is consistent with minimal residual

disease

>

>

>

> BCR_ABL transcript

>

> Major a13a2=.006%

>

> Major e14a2=not detected

>

> Major combined=.006%

>

> Minor e1a2=not detected

>

>

>

>

>

> Thanks

>

>

>

>

>

> Barbara

>

> Fayetteville, GA

>

>

>

>

[Guest guest]

O!!! YIPPEEE!!!

Number 1065 in the Zero Club

Zavie

Zavie (age 68)

67 Shoreham Avenue

Ottawa, Canada, dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

[ ] Interpretation of PCR Analysis

I haven't seen my doctor yet, but did get a copy of my latest PCR Analysis.

Wondered if someone could confirm the analysis for me. I'm anxious to know

if the Gleevec is working. I've been on 400mg since diagnosed July 06.

Results: Positive Major breakpoint (0.006%)

Interpretation=this result is consistent with minimal residual disease

BCR_ABL transcript

Major a13a2=.006%

Major e14a2=not detected

Major combined=.006%

Minor e1a2=not detected

Thanks

Barbara

Fayetteville, GA