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Re: CR monkey site

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This article (and others) refers to a 30% reduction in calories

relative to free-feeding as an " extremely low calorie diet. " I

don't think too many actual human practitioners of CR would consider

70% of their " free-feeding " diet to be extreme.

--- In , Al Pater <old542000@...>

wrote:

>

> Hi All,

>

> http://tinyurl.com/yf28we appears to be a site of

> interest with regard to ongoing rhesus monkey CR

> studies. The Photo Essay link from this page contains

> pictures plus script that exceeds that of the primary site.

>

> -- Al Pater, PhD; email: Alpater@...

>

>

>

>

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> " orb85750 " <sudarsky@...> wrote:

>

> This article (and others) refers to a 30% reduction in calories

> relative to free-feeding as an " extremely low calorie diet. " I

> don't think too many actual human practitioners of CR would consider

> 70% of their " free-feeding " diet to be extreme.

>

The 30%CR (or 70% of ad libitum food) for mice is calculated based on

a diet that does not cause the ad lib mice to fatten up. There was

much criticism on this point about the early CR experiments which

resulted in overweight ad lib mice. The fact that diets of 30%

and 40% restriction stunt growth indicates that they are quite severe.

The mature restricted mice weigh only one half as much as the ad lib

mice for a 40%CR diet, and a little bit more for 30%CR.

Similarly, for humans, the %CR should not be calculated from an

all-you-can-eat diet, but rather from a diet that would keep your BMI

in the normal range. To put it in perspective, if you are a 5'8 " male

who exercises moderately, you would need about 2200 calories to

maintain a BMI of 22, which is the middle of the normal range. A 30%

CR diet would only allow you ~1550 calories per day at the same level

of activity. Try that for a couple of weeks and let us know if you

still don't think that is severe.

Percent CR calculator:

http://www.scientificpsychic.com/health/cron1.html

Tony

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Here's what is stated in the article to which I

am referring:

---

Dieting monkeys in the study are given 30 percent fewer calories

than normal (but with full nutrition); those in the control group

get enough very healthy chow to eat as much as they want.

---

I was under the impression that " eat as much as they want "

control group average was the calorie basis from which the

30% reduction was computed. Perhaps not, but then is this

study not missing a non-free-feeding control group from

which the 30% is actually computed (if not from the free-

feeding 'eat all they want' group)?

> >

> > This article (and others) refers to a 30% reduction in calories

> > relative to free-feeding as an " extremely low calorie diet. " I

> > don't think too many actual human practitioners of CR would

consider

> > 70% of their " free-feeding " diet to be extreme.

> >

>

> The 30%CR (or 70% of ad libitum food) for mice is calculated based

on

> a diet that does not cause the ad lib mice to fatten up. There was

> much criticism on this point about the early CR experiments which

> resulted in overweight ad lib mice. The fact that diets of 30%

> and 40% restriction stunt growth indicates that they are quite

severe.

> The mature restricted mice weigh only one half as much as the ad

lib

> mice for a 40%CR diet, and a little bit more for 30%CR.

>

> Similarly, for humans, the %CR should not be calculated from an

> all-you-can-eat diet, but rather from a diet that would keep your

BMI

> in the normal range. To put it in perspective, if you are a 5'8 "

male

> who exercises moderately, you would need about 2200 calories to

> maintain a BMI of 22, which is the middle of the normal range. A

30%

> CR diet would only allow you ~1550 calories per day at the same

level

> of activity. Try that for a couple of weeks and let us know if you

> still don't think that is severe.

>

> Percent CR calculator:

> http://www.scientificpsychic.com/health/cron1.html

>

> Tony

>

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