Prostate cancer and ALA (was Walnuts, Flax, and ALMONDS?)

[Guest guest]

>Rodney wrote:

>

>>Al wrote:

>> The latest and well done study (prospective study) of

>> the association of alpha-linolenic acid (ALA) with

>> protate cancer is:

>> ...

>> Koralek DO, s U, Andriole G, Reding D, Kirsh V,

>> Subar A, Schatzkin A, R, Leitzmann MF.

>> A prospective study of dietary alpha-linolenic acid

>> and the risk of prostate cancer (United States).

>> Cancer Causes Control. 2006 Aug;17(6):783-91.

>> PMID: 16783606

>> ...

>> CONCLUSIONS: In this prospective study of

>> predominantly Caucasian men who were screened annually

>> for newly incident prostate cancer, dietary intake of

>> total ALA and ALA from specific food sources was not

>> associated with risk of total prostate cancer or

>> prostate tumors that were defined by stage and grade.

>

>Hmmmmm. Thank you for that reference. So now we have one that

>denies the connection.

Rodney,

There's more than *one* such study.

I think it's more accurate to say that there has been controversy.

Here's another not too old study indicating

" Among polyunsaturated fatty acids,

linolenic acid (OR = 0.7; 95% CI: 0.6-0.9) and

linoleic acid (OR = 0.8; 95% CI: 0.6-1.0)

were inversely related to prostate cancer. "

Bidoli E, Talamini R, Bosetti C, Negri E, Maruzzi D, Montella M,

Franceschi S, La Vecchia C.

Macronutrients, fatty acids, cholesterol and prostate cancer risk.

Ann Oncol. 2005 Jan;16(1):152-7.

Servizio di Epidemiologia e Biostatistica,

Centro di Riferimento Oncologico, Aviano (PN), Italy.

BACKGROUND: The role of selected macronutrients, fatty acids and

cholesterol in the etiology of prostate cancer was analyzed using

data from a case-control study carried out in five Italian areas

between 1991 and 2002.

PATIENTS AND METHODS: Cases were 1294 men with incident,

histologically confirmed prostate cancer, and admitted to the

major teaching and general hospitals of study areas. Controls were

1451 men admitted for acute, non-neoplastic conditions to the same

hospital network.

PMID: 15598953

Thanks,

Todd