Re: Scientists identify agent that regulates appetite

[Guest guest]

Hi folks:

This study posted by Diane is very interesting. And might,

conceivably, be a solution to the obesity epidemic .............

great for the drug companies, and easy, just one more pill to pop.

Maybe.

HOWEVER, this might be counter-productive for people on CRON. There

was a discussion here a while ago, about some studies originally

posted by ('pct'). These appeared to indicate that the life

extension benefits obtained from CRON might be derived from the exact

same mechanism that creates the sensation of hunger. So without the

hunger, perhaps, there would be no remarkable degree of life

extension.

's original post on this was # 19,795. A couple of (my)

responses were posts #s 19,798 and 19,799.

I do not believe we came to a definitive conclusion about this. If

anyone has information that would help reach a conclusion it would be

great to see it posted.

In the meantime, while I do tend to eat bulky, low calorie, foods I

have to date avoided things like guar which in effect, so far as I

know, serve pretty much only the purpose of getting rid of hunger.

So far I have not had huge problems putting up with the hunger on

CRON. I do sometimes wonder if that is a disadvantage and whether if

I restricted a little more I would be a little more hungry and

increase my potential life expectancy.

Rodney.

>

>

> HONG KONG (Reuters) - Scientists in Japan have identified a molecule

> responsible for making mammals feel full, a discovery that could

lead

> to new ways to treat obesity in humans.

>

> Scientists believe appetite is controlled in a region of the brain

> called the hypothalamus, and the group of researchers claims to be

the

> first to pinpoint an agent that triggers an increase or decrease in

> appetite.

>

> In an article published on Sunday in the online version of the

journal

> Nature, the scientists identified the molecule as nesfatin-1, which

is

> produced naturally in the brain.

>

> After injecting the molecule into the brains of rats, the scientists

> observed that the rodents began to eat less and lose weight.

>

> The researchers also were able to induce the rats to eat more, by

> blocking nesfatin-1.

>

> " After we injected anti-nesfatin-1 antibody, these rats showed

> increased appetite and finally showed a progressive increase in body

> weight, " Masatomo Mori of the medicine and molecular science

> department at Gunma University Graduate School of Medicine told

> Reuters in a telephone interview.

>

> Mori said the finding could pave the way for treating obesity, which

> has become a major health problem in the developing world as well as

> in economically advanced countries.

>

> There are at least a billion overweight adults across the world, 300

> million of them considered obese, according to the

> World Health Organization.

>

> Obesity has been linked to chronic diseases, such as type 2

diabetes,

> cardiovascular disease, hypertension and stroke, and some forms of

> cancer.

>

> Source:

> http://news./s/nm/20061001/sc_nm/appetite_dc

>

> - Diane

>