Re: Green tea linked to long life in Japanese study

[Guest guest]

Hi All,

The below articles introduce and present some details

of a pdf-availed study on the benefits of drinking

green tea.

Diane has introduced the topic with:

http://apnews.excite.com/article/20060912/D8K3HHV00.html

http://news./s/nm/20060912/hl_nm/tea_dc

This Week in JAMA

Green Tea Consumption and Mortality

JAMA. 2006;296:1203.

In vitro and animal data suggest that green tea

consumption may protect against cardiovascular disease

(CVD) and cancer, but data from human studies are

lacking. Kuriyama and colleagues report results of a

prospective cohort study of Japanese adults who had no

history of CVD or cancer at baseline. During 11 years

of follow-up, the authors found significant inverse

associations of green tea consumption with reduced

all-cause and CVD mortality, particularly among women,

but found no association with cancer mortality.

Green Tea Consumption and Mortality Due to

Cardiovascular Disease, Cancer, and All Causes in

Japan: The Ohsaki Study

Shinichi Kuriyama; Taichi Shimazu; Kaori Ohmori;

Nobutaka Kikuchi; Naoki Nakaya; Yoshikazu Nishino;

Yoshitaka Tsubono; Ichiro Tsuji

JAMA. 2006;296:1255-1265.

... The Ohsaki National Health Insurance Cohort

Study, a population-based, prospective cohort study

initiated in 1994 among 40 530 Japanese adults aged 40

to 79 years without history of stroke, coronary heart

disease, or cancer at baseline. Participants were

followed up for up to 11 years (1995-2005) for

all-cause mortality and for up to 7 years (1995-2001)

for cause-specific mortality.

... Results Over 11 years of follow-up

(follow-up rate, 86.1%), 4209 participants died, and

over 7 years of follow-up (follow-up rate, 89.6%), 892

participants died of cardiovascular disease and 1134

participants died of cancer. Green tea consumption was

inversely associated with mortality due to all causes

and due to cardiovascular disease. The inverse

association with all-cause mortality was stronger in

women (P = .03 for interaction with sex). In men, the

multivariate hazard ratios of mortality due to all

causes associated with different green tea consumption

frequencies were 1.00 (reference) for less than 1

cup/d, 0.93 (95% confidence interval [CI], 0.83-1.05)

for 1 to 2 cups/d, 0.95 (95% CI, 0.85-1.06) for 3 to 4

cups/d, and 0.88 (95% CI, 0.79-0.98) for 5 or more

cups/d, respectively (P = .03 for trend). The

corresponding data for women were 1.00, 0.98 (95% CI,

0.84-1.15), 0.82 (95% CI, 0.70-0.95), and 0.77 (95%

CI, 0.67-0.89), respectively (P<.001 for trend). The

inverse association with cardiovascular disease

mortality was stronger than that with all-cause

mortality. This inverse association was also stronger

in women (P = .08 for interaction with sex). In women,

the multivariate hazard ratios of cardiovascular

disease mortality across increasing green tea

consumption categories were 1.00, 0.84 (95% CI,

0.63-1.12), 0.69 (95% CI, 0.52-0.93), and 0.69 (95%

CI, 0.53-0.90), respectively (P = .004 for trend).

Among the types of cardiovascular disease mortality,

the strongest inverse association was observed for

stroke mortality. In contrast, the hazard ratios of

cancer mortality were not significantly different from

1.00 in all green tea categories compared with the

lowest-consumption category.

Conclusion Green tea consumption is associated

with reduced mortality due to all causes and due to

cardiovascular disease but not with reduced mortality

due to cancer.

... frequency of recent average consumption of 4

beverages (green tea, oolong tea, black tea, and

coffee) ...

Table 3. Proportional Hazard Ratios (HRs) for

11-Year Mortality Due to All Causes by Green Tea

Consumption in Japanese Adults

==================================================================

---Green Tea Consumption, Cups/d---

Mortality Outcomes---<1 1-2 3-4 =/>5---PTrend

==================================================================

Total Participants

No. of person-years 97 127 80 416 82 121 114 510

No. of deaths 1109 872 920 1308

Age- and sex-adjusted HR (95% CI) 1.00 0.94

(0.86-1.03) 0.88 (0.80-0.96) 0.83 (0.77-0.90) <.001

Multivariate HR (95% CI)^* 1.00 0.96 (0.87-1.05) 0.90

(0.82-0.98) 0.84 (0.77-0.92) <.001

Multivariate HR (95% CI)^§ 1.00 0.95 (0.85-1.05) 0.92

(0.83-1.02) 0.85 (0.77-0.94) .001

Men

No. of person-years 53 348 39 678 35 984 47 273

No. of deaths 747 541 584 796

Age-adjusted HR (95% CI) 1.00 0.96 (0.86-1.07) 0.95

(0.86-1.06) 0.89 (0.81-0.99) .03

Multivariate HR (95% CI)^* 1.00 0.93 (0.83-1.05) 0.95

(0.85-1.06) 0.88 (0.79-0.98) .03

Multivariate HR (95% CI)^§ 1.00 0.94 (0.82-1.07) 0.97

(0.85-1.10) 0.88 (0.78-1.00) .07

Women

No. of person-years 43 779 40 738 46 137 67 238

No. of deaths 362 331 336 512

Age-adjusted HR (95% CI) 1.00 0.91 (0.78-1.05) 0.75

(0.65-0.87) 0.74 (0.64-0.84) <.001

Multivariate HR (95% CI)^* 1.00 0.98 (0.84-1.15) 0.82

(0.70-0.95) 0.77 (0.67-0.89) <.001

Multivariate HR (95% CI)^§ 1.00 0.96 (0.81-1.15) 0.86

(0.72-1.02) 0.80 (0.68-0.94) .003

==================================================================

Abbreviation: CI, confidence interval.

^*The multivariate HR has been adjusted for age

(continuous variable), sex (among total participants),

job status (employed vs unemployed), years of

education (<10, 10-12, or =/>13), body mass index

(calculated as weight in kilograms divided by height

in meters squared; <18.5, 18.5-22.9, 23.0-24.9,

25.0-29.9, or =/>30.0), engaging in sports or exercise

(<1, 1-2, or =/>3 h/wk), walking duration (<1 vs =/>1

h/d), history of hypertension, diabetes mellitus, and

gastric ulcer (for each disease, yes or no), smoking

status (never, former, currently smoking <20, or

currently smoking =/>20 cigarettes/d), alcohol

drinking (never, former, currently drinking <45.6 g/d,

or currently drinking =/>45.6 g/d ethanol), total

energy intake per day (continuous variable), daily

consumption of rice (<3, 3, 4, or =/>5 bowls), daily

consumption of miso (soybean paste) soup (yes or no),

daily consumption of soybean products, total meat,

total fish, dairy products, total fruits, and total

vegetables (for each food, continuous variable), and

consumption of oolong tea, black tea, and coffee (for

each beverage, never or occasionally, 1-2 cups/d, or

=/>3 cups/d).

^§Participants who died in the first 3 years of

follow-up were excluded from this analysis.

Table 4. Proportional Hazard Ratios (HRs) for

7-Year Mortality Due to Cardiovascular Disease and

Cancer by Green Tea Consumption in Japanese Adults

==================================================================

---Green Tea Consumption, Cups/d---

Mortality Outcomes---<1 1-2 3-4 =/>5---PTrend

==================================================================

Total Participants

No. of person-years 65 656 54 443 55 290 76 712

Cardiovascular disease mortality

No. of deaths 261 186 182 263

Age- and sex-adjusted HR (95% CI) 1.00 0.83

(0.69-1.00) 0.70 (0.58-0.85) 0.67 (0.57-0.80) <.001

Multivariate HR (95% CI)^* 1.00 0.87 (0.72-1.06) 0.77

(0.63-0.93) 0.74 (0.62-0.89) <.001

Multivariate HR (95% CI)^§ 1.00 0.76 (0.59-0.97) 0.77

(0.60-0.98) 0.74 (0.59-0.92) .01

Cancer mortality

No. of deaths 256 229 265 384

Age- and sex-adjusted HR (95% CI) 1.00 1.08

(0.91-1.29) 1.13 (0.95-1.34) 1.11 (0.95-1.30) .21

Multivariate HR (95% CI)^* 1.00 1.11 (0.93-1.34) 1.16

(0.97-1.38) 1.11 (0.94-1.31) .25

Multivariate HR (95% CI)^§ 1.00 1.12 (0.89-1.41) 1.17

(0.94-1.46) 1.11 (0.90-1.37) .36

Men

No. of person-years 36 003 26 885 24 250 31 718

Cardiovascular disease mortality

No. of deaths 149 103 98 131

Age-adjusted HR (95% CI) 1.00 0.91 (0.71-1.17) 0.79

(0.61-1.02) 0.73 (0.58-0.92) .005

Multivariate HR (95% CI)^* 1.00 0.88 (0.68-1.14) 0.84

(0.64-1.09) 0.78 (0.61-1.00) .05

Multivariate HR (95% CI)^§ 1.00 0.82 (0.59-1.16) 0.91

(0.65-1.27) 0.87 (0.64-1.19) .49

Cancer mortality

No. of deaths 179 142 175 243

Age-adjusted HR (95% CI) 1.00 1.04 (0.84-1.30) 1.21

(0.98-1.48) 1.16 (0.96-1.41) .08

Multivariate HR (95% CI)^* 1.00 1.02 (0.82-1.28) 1.18

(0.95-1.46) 1.11 (0.90-1.36) .22

Multivariate HR (95% CI)^§ 1.00 1.02 (0.77-1.35) 1.13

(0.86-1.48) 1.04 (0.80-1.35) .66

Women

No. of person-years 29 653 27 558 31 040 44 995

Cardiovascular disease mortality

No. of deaths 112 83 84 132

Age-adjusted HR (95% CI) 1.00 0.74 (0.55-0.98) 0.61

(0.46-0.81) 0.62 (0.48-0.80) <.001

Multivariate HR (95% CI)^* 1.00 0.84 (0.63-1.12) 0.69

(0.52-0.93) 0.69 (0.53-0.90) .004

Multivariate HR (95% CI)^§ 1.00 0.68 (0.47-0.98) 0.65

(0.45-0.93) 0.61 (0.44-0.85) .006

Cancer mortality

No. of deaths 77 87 90 141

Age-adjusted HR (95% CI) 1.00 1.14 (0.84-1.55) 0.97

(0.72-1.32) 1.00 (0.75-1.32) .68

Multivariate HR (95% CI)^* 1.00 1.27 (0.93-1.74) 1.09

(0.79-1.49) 1.07 (0.80-1.44) .97

Multivariate HR (95% CI)^§ 1.00 1.34 (0.90-1.98) 1.22

(0.83-1.79) 1.20 (0.83-1.73) .53

==================================================================

Abbreviation: CI, confidence interval.

^*The multivariate HR has been adjusted for age

(continuous variable), sex (among total participants),

job status (employed vs unemployed), years of

education (<10, 10-12, or =/>13), body mass index

(calculated as weight in kilograms divided by height

in meters squared; <18.5, 18.5-22.9, 23.0-24.9,

25.0-29.9, or =/>30.0), engaging in sports or exercise

(<1, 1-2, or =/>3 h/wk), walking duration (<1 vs =/>1

h/d), history of hypertension, diabetes mellitus, and

gastric ulcer (for each disease, yes or no), smoking

status (never, former, currently smoking <20, or

currently smoking =/>20 cigarettes/d), alcohol

drinking (never, former, currently drinking <45.6 g/d,

or currently drinking =/>45.6 g/d ethanol), total

energy intake per day (continuous variable), daily

consumption of rice (<3, 3, 4, or =/>5 bowls), daily

consumption of miso (soybean paste) soup (yes or no),

daily consumption of soybean products, total meat,

total fish, dairy products, total fruits, and total

vegetables (for each food, continuous variable), and

consumption of oolong tea, black tea, and coffee (for

each beverage, never or occasionally, 1-2 cups/d, or

=/>3 cups/d).

^§Participants who died in the first 3 years of

follow-up were excluded from this analysis.

Table 5. Proportional Hazard Ratios (HRs) Among

All Participants for 7-Year Mortality Due to

Cardiovascular Disease and Cancer Subtypes by Green

Tea Consumption in Japanese Adults

==================================================================

---Green Tea Consumption, Cups/d---

Mortality Outcomes---<1 1-2 3-4 =/>5---PTrend

==================================================================

Coronary heart disease

No. of deaths 58 47 43 61

Multivariate HR (95% CI)^* 1.00 1.04 (0.70-1.56) 0.90

(0.60-1.36) 0.86 (0.59-1.26) .34

Stroke

No. of deaths 145 99 102 126

Multivariate HR (95% CI)^* 1.00 0.84 (0.65-1.09) 0.78

(0.60-1.01) 0.63 (0.49-0.82) <.001

Cerebral infarction

No. of deaths 65 41 48 43

Multivariate HR (95% CI)^* 1.00 0.77 (0.52-1.15) 0.81

(0.55-1.19) 0.49 (0.33-0.73) .001

Cerebral hemorrhage

No. of deaths 34 30 33 40

Multivariate HR (95% CI)^* 1.00 1.10 (0.66-1.82) 1.15

(0.70-1.89) 0.98 (0.60-1.58) .94

Subarachnoid hemorrhage

No. of deaths 21 13 12 26

Multivariate HR (95% CI)^* 1.00 0.71 (0.35-1.44) 0.57

(0.27-1.17) 0.78 (0.42-1.43) .42

Gastric cancer

No. of deaths 44 44 38 67

Multivariate HR (95% CI)^* 1.00 1.33 (0.86-2.04) 1.00

(0.64-1.58) 1.17 (0.78-1.76) .72

Lung cancer

No. of deaths 49 41 46 82

Multivariate HR (95% CI)^* 1.00 1.03 (0.67-1.58) 1.05

(0.69-1.59) 1.18 (0.81-1.72) .36

Colorectal cancer

No. of deaths 30 24 36 42

Multivariate HR (95% CI)^* 1.00 1.04 (0.59-1.82) 1.45

(0.87-2.41) 1.10 (0.67-1.82) .54

==================================================================

Abbreviation: CI, confidence interval.

^*The multivariate HR has been adjusted for age

(continuous variable), sex, job status (employed vs

unemployed), years of education (<10, 10-12, or

=/>13), body mass index (calculated as weight in

kilograms divided by height in meters squared; <18.5,

18.5-22.9, 23.0-24.9, 25.0-29.9, or =/>30.0), engaging

in sports or exercise (<1, 1-2, or =/>3 h/wk), walking

duration (<1 vs =/>1 h/d), history of hypertension,

diabetes mellitus, and gastric ulcer (for each

disease, yes or no), smoking status (never, former,

currently smoking <20, or currently smoking =/>20

cigarettes/d), alcohol drinking (never, former,

currently drinking <45.6 g/d, or currently drinking

=/>45.6 g/d ethanol), total energy intake per day

(continuous variable), daily consumption of rice (<3,

3, 4, or =/>5 bowls), daily consumption of miso

(soybean paste) soup (yes or no), daily consumption of

soybean products, total meat, total fish, dairy

products, total fruits, and total vegetables (for each

food, continuous variable), and consumption of oolong

tea, black tea, and coffee (for each beverage, never

or occasionally, 1-2 cups/d, or =/>3 cups/d).

Table 6. Proportional Hazard Ratios (HRs) Among

Men for 7-Year Mortality Due to Cardiovascular Disease

and Cancer Subtypes by Green Tea Consumption in

Japanese Adults

==================================================================

---Green Tea Consumption, Cups/d---

Mortality Outcomes---<1 1-2 3-4 =/>5---PTrend

==================================================================

Coronary heart disease

No. of deaths 37 29 27 36

Multivariate HR (95% CI)^* 1.00 1.03 (0.62-1.71) 0.96

(0.57-1.62) 0.91 (0.56-1.48) .66

Stroke

No. of deaths 79 53 59 58

Multivariate HR (95% CI)^* 1.00 0.85 (0.60-1.22) 0.97

(0.68-1.37) 0.65 (0.45-0.93) .04

Cerebral infarction

No. of deaths 37 23 33 23

Multivariate HR (95% CI)^* 1.00 0.78 (0.45-1.34) 1.16

(0.71-1.91) 0.58 (0.33-1.00) .15

Cerebral hemorrhage

No. of deaths 21 15 17 21

Multivariate HR (95% CI)^* 1.00 0.91 (0.46-1.78) 1.08

(0.56-2.09) 1.01 (0.53-1.91) .88

Subarachnoid hemorrhage

No. of deaths 10 5 3 5

Multivariate HR (95% CI)^* 1.00 0.58 (0.19-1.73) 0.37

(0.10-1.38) 0.37 (0.11-1.27) .08

Gastric cancer

No. of deaths 32 30 30 46

Multivariate HR (95% CI)^* 1.00 1.29 (0.78-2.16) 1.19

(0.71-2.00) 1.20 (0.74-1.95) .55

Lung cancer

No. of deaths 43 29 34 60

Multivariate HR (95% CI)^* 1.00 0.88 (0.54-1.42) 0.97

(0.61-1.54) 1.14 (0.75-1.73) .46

Colorectal cancer

No. of deaths 22 18 21 23

Multivariate HR (95% CI)^* 1.00 1.09 (0.57-2.09) 1.23

(0.66-2.29) 0.88 (0.47-1.63) .74

==================================================================

Abbreviation: CI, confidence interval.

^*The multivariate HR has been adjusted for age

(continuous variable), job status (employed vs

unemployed), years of education (<10, 10-12, or

=/>13), body mass index (calculated as weight in

kilograms divided by height in meters squared; <18.5,

18.5-22.9, 23.0-24.9, 25.0-29.9, or =/>30.0), engaging

in sports or exercise (<1, 1-2, or =/>3 h/wk), walking

duration (<1 vs =/>1 h/d), history of hypertension,

diabetes mellitus, and gastric ulcer (for each

disease, yes or no), smoking status (never, former,

currently smoking <20, or currently smoking =/>20

cigarettes/d), alcohol drinking (never, former,

currently drinking <45.6 g/d, or currently drinking

=/>45.6 g/d ethanol), total energy intake per day

(continuous variable), daily consumption of rice (<3,

3, 4, or =/>5 bowls), daily consumption of miso

(soybean paste) soup (yes or no), daily consumption of

soybean products, total meat, total fish, dairy

products, total fruits, and total vegetables (for each

food, continuous variable), and consumption of oolong

tea, black tea, and coffee (for each beverage, never

or occasionally, 1-2 cups/d, or =/>3 cups/d).

Table 7. Proportional Hazard Ratios (HRs) Among

Women for 7-Year Mortality Due to Cardiovascular

Disease and Cancer Subtypes

by Green Tea Consumption in Japanese Adults

==================================================================

---Green Tea Consumption, Cups/d---

Mortality Outcomes---<1 1-2 3-4 =/>5---PTrend

==================================================================

Coronary heart disease

No. of deaths 21 18 16 25

Multivariate HR (95% CI)^* 1.00 1.04 (0.54-2.01) 0.79

(0.40-1.56) 0.77 (0.42-1.44) .31

Stroke

No. of deaths 66 46 43 68

Multivariate HR (95% CI)^* 1.00 0.79 (0.53-1.16) 0.61

(0.41-0.90) 0.58 (0.41-0.84) .002

Cerebral infarction

No. of deaths 28 18 15 20

Multivariate HR (95% CI)^* 1.00 0.76 (0.41-1.39) 0.47

(0.24-0.89) 0.38 (0.21-0.69) <.001

Cerebral hemorrhage

No. of deaths 13 15 16 19

Multivariate HR (95% CI)^* 1.00 1.33 (0.61-2.90) 1.32

(0.61-2.82) 0.98 (0.46-2.09) .87

Subarachnoid hemorrhage

No. of deaths 11 8 9 21

Multivariate HR (95% CI)^* 1.00 0.80 (0.32-2.03) 0.71

(0.29-1.75) 1.05 (0.49-2.26) .81

Gastric cancer

No. of deaths 12 14 8 21

Multivariate HR (95% CI)^* 1.00 1.32 (0.59-2.94) 0.64

(0.26-1.63) 1.08 (0.50-2.33) .84

Lung cancer

No. of deaths 6 12 12 22

Multivariate HR (95% CI)^* 1.00 1.83 (0.68-4.96) 1.46

(0.54-3.95) 1.59 (0.63-4.05) .54

Colorectal cancer

No. of deaths 8 6 15 19

Multivariate HR (95% CI)^* 1.00 0.98 (0.32-2.97) 1.96

(0.78-4.95) 1.49 (0.60-3.71) .26

==================================================================

Abbreviation: CI, confidence interval.

^*The multivariate HR has been adjusted for age

(continuous variable), job status (employed vs

unemployed), years of education (<10, 10-12, or

=/>13), body mass index (calculated as weight in

kilograms divided by height in meters squared;<18.5,

18.5-22.9, 23.0-24.9, 25.0-29.9, or=/>30.0), engaging

in sports or exercise (<1, 1-2, or=/>3 h/wk), walking

duration (<1 vs =/>1 h/d), history of hypertension,

diabetes mellitus, and gastric ulcer (for each

disease, yes or no), smoking status (never, former,

currently smoking <20, or currently smoking =/>20

cigarettes/d), alcohol drinking (never, former,

currently drinking<45.6 g/d, or currently

drinking=/>45.6 g/d ethanol), total energy intake per

day (continuous variable), daily consumption of rice

(<3, 3, 4, or=/>5 bowls), daily consumption of miso

(soybean paste) soup (yes or no), daily consumption of

soybean products, total meat, total fish, dairy

products, total fruits, and total vegetables (for each

food, continuous variable), and consumption of oolong

tea, black tea, and coffee (for each beverage, never

or occasionally, 1-2 cups/d, or =/>3 cups/d).

Table 8. Proportional Hazard Ratios (HRs) for

11-Year Mortality Due to All Causes by Type of Tea

Consumption in Japanese Adults

==================================================================

---Tea Consumption, Cups/d---

Mortality Outcomes---<1 1-2 3-4 =/>5---PTrend

==================================================================

Green tea

No. of person-years 97 127 80 416 196 631

No. of deaths 1109 872 2228

Multivariate HR (95% CI)^* 1.00 0.96 (0.87-1.05) 0.87

(0.80-0.93) <.001

Oolong tea (Chinese tea)

No. of person-years 256 266 15 909 14 715

No. of deaths 2646 135 122

Multivariate HR (95% CI)^* 1.00 1.01 (0.84-1.21) 1.03

(0.85-1.25) .76

Black tea

No. of person-years 271 605 8313 2712

No. of deaths 2750 87 33

Multivariate HR (95% CI)^* 1.00 1.00 (0.79-1.25) 1.04

(0.72-1.51) .89

Abbreviation: CI, confidence interval.

^*The multivariate HR has been adjusted for age

(continuous variable), sex, job status (employed vs

unemployed), years of education (<10, 10-12, or

=/>13), body mass index (calculated as weight in

kilograms divided by height in meters squared; <18.5,

18.5-22.9, 23.0-24.9, 25.0-29.9, or =/>30.0), engaging

in sports or exercise (<1, 1-2, or =/>3 h/wk), walking

duration (<1 vs =/>1 h/d), history of hypertension,

diabetes mellitus, and gastric ulcer (for each

disease, yes or no), smoking status (never, former,

currently smoking <20, or currently smoking =/>20

cigarettes/d), alcohol drinking (never, former,

currently drinking <45.6 g/d, or currently drinking

=/>45.6 g/d ethanol), total energy intake per day

(continuous variable), daily consumption of rice (<3,

3, 4, or =/>5 bowls), daily consumption of miso

(soybean paste) soup (yes or no), daily consumption of

soybean products, total meat, total fish, dairy

products, total fruits, and total vegetables (for each

food, continuous variable), and consumption of green

tea, oolong tea, black tea, and coffee (for each

beverage, never or occasionally, 1-2 cups/d, or =/>3

cups/d). Models for green tea, oolong tea, or black

tea did not include these variables, respectively.

-- Al Pater, alpater@...

--- Diane Walter <dianepwalter@...> wrote:

> http://news./s/nm/20060912/hl_nm/tea_dc

>

> A study of more than 40,000 men and women in Japan

> has found that

> those who drink a lot of green tea live longer,

> researchers said on

> Tuesday.

-- Al Pater, PhD; email: old542000@...

__________________________________________________

[Guest guest]

Hi folks:

Well, sorry to be the devil's advocate here. But my take on these

numbers is a little different from that of the media. It is far from

clear to me that these data suggest green tea will benefit people on

CRON. Indeed, perhaps the opposite.

People on CRON have hugely improved risk factor data for CVD. If CVD

incidence among us will reflect our risk factor data (does it make

sense to assume otherwise?) then not many of us are going to have a

problem with CVD.

In most countries, after CVD the largest cause of death is cancer.

Certainly, there are reasons to believe our risk of cancer is also

significantly reduced, but based on our lipids test measurements it

seems likely cancer will be a much bigger issue for us than CVD.

So what do these green tea consumption data show for cancer? Well,

while the numbers are not statistically significant, for cancer in

the aggregate and for each of the sub-types they show data for, in

EVERY case the hazard is GREATER for those who drink green tea than

for those who do not.

There does seem to be a meaningful reduction in risk of subarachnoid

hemorrhage.

We need to see the results of further studies. But these data do not

persuade me that people on CRON will live longer if they drink green

tea. We may experience a reduction in a minimal (CVD) risk, but an

increase in a larger (cancer) risk. It is especially interesting

that green tea shows no signs of reducing gastric cancer. It

certainly would have been expected that if the polyphenols in tea

have benefit this would be shown clearly in the intestines.

Apparently not.

Jmo.

[up until now I have drunk a considerable amount of tea, of various

types. I will be interested to see what further research shows.]

Rodney.

>

> > http://news./s/nm/20060912/hl_nm/tea_dc

> >

> > A study of more than 40,000 men and women in Japan

> > has found that

> > those who drink a lot of green tea live longer,

> > researchers said on

> > Tuesday.

>

> -- Al Pater, PhD; email: old542000@...

>

> __________________________________________________

>

[Guest guest]

Hi folks:

Worth remembering that if you do a search in Pubmed using the

terms " tea bone density " most of the studies, but not all, find tea

drinking helps preserve bone mass. So CVD and cancer are not the

only issues that may be relevant here.

Rodney.

> >

> > > http://news./s/nm/20060912/hl_nm/tea_dc

> > >

> > > A study of more than 40,000 men and women in Japan

> > > has found that

> > > those who drink a lot of green tea live longer,

> > > researchers said on

> > > Tuesday.

> >

> > -- Al Pater, PhD; email: old542000@

> >

> > __________________________________________________

> >