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RE: I.V. Asprin

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Ricky,

The stuff we used before was " Aspegic " made in Brussels I think, mainly used

as an IV anti-Pyretic, We stopped using it as it was abused and used on

everyone in some cases even in Children. If your looking for an IV

relatively safe anti-pyretic it might be worth looking at Prodafalgon which

is also made in Brussels and is a form if IV paracetamol and safe for kids.

Not sure of the manufacture but try Rumsey in Cambridge he can

source either for you.

>From: " ricky_nightingale " <ricky@...>

>Reply-

>

>Subject: I.V. Asprin

>Date: Sun, 10 Oct 2004 16:59:44 -0000

>

>

>

>Hi guys,

>I am enquiring about I.V. aspirin, dosage, Indications,

>manufacturers, etc. This is mainly directed towards Brash as i

>know you are aware of the drug , but i would welcome input from

>anyone else.

>Regards,

>Ricky.

>

>

>

>

>

>

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--- paul brash <pbrash@...> wrote:

>

> Ricky,

>

> The stuff we used before was " Aspegic " made in Brussels I think,

> mainly used as an IV anti-Pyretic, We stopped using it as it was

> abused and used on everyone in some cases even in Children. If

> your looking for an IV

> relatively safe anti-pyretic it might be worth looking at

> Prodafalgon which is also made in Brussels and is a form if IV

> paracetamol and safe for kids.

> Not sure of the manufacture but try Rumsey in Cambridge he

> can source either for you.

Hi Ricky ! ! !

If I may add :

- Their is no (zero) IV A.S.A. or IV Paracetamol in North America

- They seem to do just fine using the P.O., P.R., or N.G. routes ! ?

- Last I heard ProDafalgan was pulled from the market ?

- A.S.A. is still widely given to children, in France ! ???

- Dosages are the same

- Allergic reactions, as in any IV med is going to be more acute

- I personnaly never used it, and discouraged many a times local docs

from using it

General rules of thumb :

- If one can give something in any other way than the IV route

With relatively the same effect... then they should

- If it's a med that has a small and varied therapeutic window

Then slow titrated IV is the way to go

- Add rules ...

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> >

> > Ricky,

> >

> > The stuff we used before was " Aspegic " made in Brussels I think,

> > mainly used as an IV anti-Pyretic, We stopped using it as it was

> > abused and used on everyone in some cases even in Children. If

> > your looking for an IV

> > relatively safe anti-pyretic it might be worth looking at

> > Prodafalgon which is also made in Brussels and is a form if IV

> > paracetamol and safe for kids.

> > Not sure of the manufacture but try Rumsey in Cambridge he

> > can source either for you.

>

> Hi Ricky ! ! !

>

> If I may add :

> - Their is no (zero) IV A.S.A. or IV Paracetamol in North America

> - They seem to do just fine using the P.O., P.R., or N.G. routes ! ?

> - Last I heard ProDafalgan was pulled from the market ?

> - A.S.A. is still widely given to children, in France ! ???

> - Dosages are the same

> - Allergic reactions, as in any IV med is going to be more acute

> - I personnaly never used it, and discouraged many a times local

docs

> from using it

>

> General rules of thumb :

> - If one can give something in any other way than the IV route

> With relatively the same effect... then they should

>

> - If it's a med that has a small and varied therapeutic window

> Then slow titrated IV is the way to go

>

> - Add rules ...

>

>

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,

We don't give aspirin to kids anymore in the uK because of Reyes syndrome.

ASA and Paracetamol IV are not so much banned in the UK just never licensed

would cost too much for little benifit, I agree I see no real need for IV

anti-pyretics genarally yu can Give paracetamol both ends !!

>From: Brault <c_brault@...>

>Reply-

>

>Subject: RE: I.V. Asprin

>Date: Mon, 11 Oct 2004 06:50:18 -0700 (PDT)

>

>--- paul brash <pbrash@...> wrote:

> >

> > Ricky,

> >

> > The stuff we used before was " Aspegic " made in Brussels I think,

> > mainly used as an IV anti-Pyretic, We stopped using it as it was

> > abused and used on everyone in some cases even in Children. If

> > your looking for an IV

> > relatively safe anti-pyretic it might be worth looking at

> > Prodafalgon which is also made in Brussels and is a form if IV

> > paracetamol and safe for kids.

> > Not sure of the manufacture but try Rumsey in Cambridge he

> > can source either for you.

>

>Hi Ricky ! ! !

>

>If I may add :

>- Their is no (zero) IV A.S.A. or IV Paracetamol in North America

>- They seem to do just fine using the P.O., P.R., or N.G. routes ! ?

>- Last I heard ProDafalgan was pulled from the market ?

>- A.S.A. is still widely given to children, in France ! ???

>- Dosages are the same

>- Allergic reactions, as in any IV med is going to be more acute

>- I personnaly never used it, and discouraged many a times local docs

>from using it

>

>General rules of thumb :

>- If one can give something in any other way than the IV route

>With relatively the same effect... then they should

>

>- If it's a med that has a small and varied therapeutic window

>Then slow titrated IV is the way to go

>

>- Add rules ...

>

>

>

>

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Hi,

In message <20041011135018.61465.qmail@...> Brault

<c_brault@...> writes:

>

> --- paul brash <pbrash@...> wrote:

> >

> > Ricky,

> >

> > The stuff we used before was " Aspegic " made in Brussels I think,

> > mainly used as an IV anti-Pyretic, We stopped using it as it was

> > abused and used on everyone in some cases even in Children. If

> > your looking for an IV

> > relatively safe anti-pyretic it might be worth looking at

> > Prodafalgon which is also made in Brussels and is a form if IV

> > paracetamol and safe for kids.

> > Not sure of the manufacture but try Rumsey in Cambridge he

> > can source either for you.

>

> Hi Ricky ! ! !

>

> If I may add :

> - Their is no (zero) IV A.S.A. or IV Paracetamol in North America

> - They seem to do just fine using the P.O., P.R., or N.G. routes ! ?

> - Last I heard ProDafalgan was pulled from the market ?

Replaced by Perfalgan, which is i/v paracetamol, marketed as Perfalgan.

ProDafalgan was pro-paracetamol, which was a powder which was irritant on

infusion. New stuff comes prepared in 100mL solution and costs 1.50 GBP each.

The literature with it states that is equivalent to 10mg morphine i/m and has a

morphine sparing effect when used with a patient-controlled morphine pump.

> - A.S.A. is still widely given to children, in France ! ???

> - Dosages are the same

> - Allergic reactions, as in any IV med is going to be more acute

> - I personnaly never used it, and discouraged many a times local docs

> from using it

VERY low incidence of allergic reactions to paracetamol.

>

> General rules of thumb :

> - If one can give something in any other way than the IV route

> With relatively the same effect... then they should

General principle would be to avoid the GI system as a route of administration

in an emergency situation - we ask our patients to chew their aspirin in an MI

....

Cheers

Anton

>

> - If it's a med that has a small and varied therapeutic window

> Then slow titrated IV is the way to go

>

> - Add rules ...

>

>

>

>

>

>

>

> Member Information:

>

> List owner: Ian Sharpe Owner@...

> Editor: Ross Boardman Editor@...

>

> ALL list admin messages (subscriptions & unsubscriptions) should be sent to

the list owner.

>

> Post message: egroups

>

> Please visit our website http://www.remotemedics.co.uk

>

> Regards

>

> The Remote Medics Team

>

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--- anton.vandellen@... wrote:

> > If I may add :

> > - Their is no (zero) IV A.S.A. or IV Paracetamol in North America

> > - They seem to do just fine using the P.O., P.R., or N.G. routes

> ! ?

> > - Last I heard ProDafalgan was pulled from the market ?

>

> Replaced by Perfalgan, which is i/v paracetamol, marketed as

> Perfalgan. ProDafalgan was pro-paracetamol, which was a powder

> which was irritant on infusion. New stuff comes prepared in 100mL

> solution and costs 1.50 GBP each.

Thanks for the update !

>

> > - A.S.A. is still widely given to children, in France ! ???

Note the " ??? "

Geography, History & Culture

Still have a fair amount of influence out their

As we can all attest too !

Peds ASA is pretty close to Taboo in N-A

> > - Allergic reactions, as in any IV med is going to be more acute

>

> VERY low incidence of allergic reactions to paracetamol.

Indeed

Very, very safe medication

(bar some rare Hepatic probs & Nasty Overdoses)

Wich we can't say the same of ASA

Otherwise the statement was general

And absolutely holds true

>

> >

> > General rules of thumb :

> > - If one can give something in any other way than the IV route

> > With relatively the same effect... then they should

>

> General principle would be to avoid the GI system as a route of

> administration in an emergency situation - we ask our patients to

> chew their aspirin in an MI ...

Indeed

Even the SQ route is not indicated in some emergencies

(SQ Epi in some anaphylaxis)

I meant my statement to fully acknowledge these nuances

" With relatively the same effect... then they should "

Un-chewed ASA does not have the same effect as if was chewed

And, even then, may not have the same effect

If the Pt is in schock !

Not only in the speed of action

But also in the accumulation, timing & distribution of the dose

Note:

I don't think we disagree on anything

I am merely throwing more meet on the bone

.... just a lazy Sunday

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Hi ,

Quite agree we are on the same wavelength - and was being deliberately

provocative with comment on avoiding GI tract in emergencies - can use the

GI route with plenty of remote patients.

National idiosyncracies are very interestign and seldom evidence based -

eg. the use of diamporh for MIs in the UK.

Think there may well be a widespread role for i/v paracetamol, esp. as we

move to a synergistic approach to pain management - using NSAIDs,

paracetamol, codeine and opiates - certainly our approach to back pain

patients - we now say that unless there is neurological deficit, very

little reason for these patients to go to hospital at all.

Cheers

Anton

Brault said:

>

> --- anton.vandellen@... wrote:

>> > If I may add :

>> > - Their is no (zero) IV A.S.A. or IV Paracetamol in North America

>> > - They seem to do just fine using the P.O., P.R., or N.G. routes

>> ! ?

>> > - Last I heard ProDafalgan was pulled from the market ?

>>

>> Replaced by Perfalgan, which is i/v paracetamol, marketed as

>> Perfalgan. ProDafalgan was pro-paracetamol, which was a powder

>> which was irritant on infusion. New stuff comes prepared in 100mL

>> solution and costs 1.50 GBP each.

>

> Thanks for the update !

>

>>

>> > - A.S.A. is still widely given to children, in France ! ???

>

> Note the " ??? "

> Geography, History & Culture

> Still have a fair amount of influence out their

> As we can all attest too !

> Peds ASA is pretty close to Taboo in N-A

>

>> > - Allergic reactions, as in any IV med is going to be more acute

>>

>> VERY low incidence of allergic reactions to paracetamol.

>

> Indeed

> Very, very safe medication

> (bar some rare Hepatic probs & Nasty Overdoses)

> Wich we can't say the same of ASA

>

> Otherwise the statement was general

> And absolutely holds true

>

>>

>> >

>> > General rules of thumb :

>> > - If one can give something in any other way than the IV route

>> > With relatively the same effect... then they should

>>

>> General principle would be to avoid the GI system as a route of

>> administration in an emergency situation - we ask our patients to

>> chew their aspirin in an MI ...

>

> Indeed

> Even the SQ route is not indicated in some emergencies

> (SQ Epi in some anaphylaxis)

>

> I meant my statement to fully acknowledge these nuances

> " With relatively the same effect... then they should "

> Un-chewed ASA does not have the same effect as if was chewed

> And, even then, may not have the same effect

> If the Pt is in schock !

>

> Not only in the speed of action

> But also in the accumulation, timing & distribution of the dose

>

> Note:

> I don't think we disagree on anything

> I am merely throwing more meet on the bone

> ... just a lazy Sunday

>

>

>

>

>

>

>

>

> Member Information:

>

> List owner: Ian Sharpe Owner@...

> Editor: Ross Boardman Editor@...

>

> ALL list admin messages (subscriptions & unsubscriptions) should be sent

> to the list owner.

>

> Post message: egroups

>

> Please visit our website http://www.remotemedics.co.uk

>

> Regards

>

> The Remote Medics Team

>

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