Guest guest Posted September 25, 2004 Report Share Posted September 25, 2004 O.K. Who want's to do research of Re-Transfusion devices And figure out price supplier and wich ones would be more appropriate to our practice environments ? Their's a few hints/names of various devices I came across in my search : D E V I C E S J Trauma. 1975 Aug;15(8):663-9. Related Articles, Links Blood availability for the trauma patient-autotransfusion. Mattox KL, LE, Beall AC, Jordan GL. Recovery of intrathoracic and intraperitoneal blood and reinfusion by autotransfusion has been demonstrated to be safe and practical in selected trauma patients. Autotransfusion is ideally applicable to the trauma patient in whom replacement of six or fewer units of blood is required. In addition, autotransfusion provides readily available blood for patients with unusual blood types and for those in whom multiple transfusions may rapidly deplete available stores. The properties of an ideal autotransfusion device include rapid assembly, relatively low cost, ease of operation, in-line filtration, minimized air blood interface, simplified anticoagulation, and safety from air embolism and coagulopathies. Ann Vasc Surg. 1986 May;1(1):131-3. Related Articles, Links Intraoperative autotransfusion with a new disposable system. Imhoff M, Schmidt R, Horsch S. Institute of Anesthesiology, University of Koln, West Germany. In the past 2 years we have used a simple, disposable set for intraoperative autotransfusion. The system consists of a rigid plastic case with a flexible bag inside constituting a 600 ml reservoir which can be connected to any suitable vacuum source. We used it so far in 56 patients undergoing various vascular operations who were autotransfused a total of about 160 units of blood without any complications with regard to blood coagulation or hemolysis. Br J Surg. 1993 Jan;80(1):32-5. Related Articles, Links Comment in: • Br J Surg. 1993 Aug;80(8):1082. Autotransfusion in aortic surgery: the Haemocell System 350 cell saver. Kalra M, Beech MJ, al-Khaffaf H, worth D. Department of Surgery, University Hospital of South Manchester, UK. Autotransfusion was performed during elective abdominal aortic reconstruction in ten patients using the recently developed Haemocell System 350. A mean of 60 per cent of total blood loss was salvaged, and during operation each patient was autotransfused 1 unit. Good preservation of cellular components, including platelets, was seen after processing with the device, which uses a vortex mixing filter for cell separation. There was no evidence of coagulopathy; mean free plasma haemoglobin levels were slightly raised (17 mg/dl) and plasma heparin concentration was negligible (0.10 units/ml) 4 h after surgery. A transient drop in plasma fibrinogen levels and the appearance of fibrin degradation products in low concentrations (mean 1.5 mg/l) were seen. Oxyhaemoglobin dissociation curves showed the salvaged red blood cells to have a normal affinity for oxygen. Renal and hepatic function remained unaltered and there were no complications attributable to autotransfusion. The device was easy to handle and a trained operator was not required. Obstet Gynecol. 1988 Dec;72(6):947-50. Related Articles, Links A simplified device for intraoperative autotransfusion. Grimes DA. Department of Obstetrics and Gynecology, Women's Hospital, University of Southern California School of Medicine, Los Angeles. Intraoperative autotransfusion, a widely accepted adjunct in many surgical disciplines, has been underused in obstetrics and gynecology. This report describes a new device for autotransfusion that is simpler to operate than traditional systems requiring a technician. The device was used successfully in two obstetric patients with life-threatening intraoperative hemorrhage, one with abdominal pregnancy and the other with postpartum hemorrhage. The patients received autotransfusions of 1700 and 2200 mL, respectively, without incident. Advantages of autotransfusion over banked blood include avoidance of alloimmunization, reduction of transfusion reactions and blood-borne infections, less expense, and acceptance by most religious groups. Disadvantages include potential hemolysis and limited usefulness in the presence of bacterial contamination or malignancy. On balance, the benefits of autotransfusion outweigh the risks. Ugeskr Laeger. 1993 Mar 1;155(9):605-8. Related Articles, Links [solcotrans, a new autotransfusion system] [Article in Danish] Dich Nielsen JO, Skoven A, Henneberg EW, Fasting H. Anaestesi- og karkirurgisk afdeling, Skive Sygehus. Thirty-one patients scheduled to undergo aortic reconstruction were studied. 16 had aortic aneurysms and 15 required aortobifemoral grafts. The solcotrans unit comprises a rigid plastic container with an inner lining bag, into which blood is aspirated. When the bag is full (500 ml), the unit is inverted and blood is re-infused through a 40 micron filter. Sixty-three percent of the blood transfused per-operatively and 41% peri-operatively was given with the solcotrans unit. Only minor changes in the coagulation parameters were seen. Blood cultures from ten solcotrans units were all negative. Two patients contracted pneumonia, and one cystitis. We conclude that the solcotrans system is safe to use when two-to four units of blood are transfused. Further studies are required to define its role when multitransfusions of blood are needed. Anaesthesist. 1983 Nov;32(11):538-44. Related Articles, Links [Autotransfusion with the Sorensen apparatus] [Article in German] Homann B. Since 1980 in Wurzburg the Sorensen autotransfusion unit has been clinically used in 47 patients (35 vascular, 11 trauma patients, one with arterial bleeding after BII, one with aneurysm of the a. pericallosa) and tested to study its practicability, its advantages and disadvantages. Within the laboratory data there was a small decrease of hemoglobin, hematocrit and blood platelets, as well as of the " Quick " and AT-3. PTT and thrombin-time persisted unchanged, as did the results of electrolytes, parameters of renal and liver function, and the status of blood gas analysis. Free hemoglobin i.s. or i.u. was found in three patients with extremely high volume autotransfusions. The autotransfusion unit is convenient, easy to use and reliable. However, it is only suitable for the reinfusion of blood when hemorrhage is moderate and not severe. Hemothorax blood can be used only when adequate anti-fibrinolytic therapy is guaranteed. Nevertheless, the use of the Sorensen autotransfusion unit within the named diagnoses can achieve a precious contribution for saving homologous blood. J Trauma. 1987 May;27(5):537-42. Related Articles, Links Use of the Heimlich valve in a compact autotransfusion device. Schweitzer EJ, Hauer JM, Swan KG, Bresch JR, Harmon JW, Graeber GM. A compact device which evacuates blood from a hemothorax and facilitates rapid autotransfusion was evaluated in dogs. Experimental hemothorax was established surgically by incising the internal mammary artery through a thoracotomy with the animals under general anesthesia. Postoperatively the blood was drained by one of two methods. In the Heimlich valve group (n = 5), blood was drained by a chest tube through a one-way flutter valve into a collapsible plastic bag. In the Sorenson group (n = 5), blood was drained by a chest tube into the Sorenson Autotransfusion System. Blood from these two groups was then autotransfused. In the control group (n = 5), the drained blood was not autotransfused. Results showed no statistical difference between the two autotransfusion groups in the volume of blood collected, circulating fibrinogen levels, platelet counts, stroma-free hemoglobin levels, prothrombin time, or 51Cr-labeled RBC survival. There was a significant drop in the circulating platelet count, which returned to normal by 24 hours, in both groups of dogs which were autotransfused. We conclude that autotransfusion of blood collected by a compact device which utilizes a Heimlich valve and requires no suction is similar to using the Sorenson Autotransfusion System. It may be safe to use the Heimlich valve to collect blood for autotransfusion in clinical situations, where its qualities of simplicity, portability and a minimum requirement for storage space are desirable. Ther Apher. 1999 Feb;3(1):63-8. Related Articles, Links Preliminary evaluation study of a prototype hollow fiber membrane for the continuous membrane autotransfusion system. Fukunaga K, Shimoyama T, Sueoka A, Nose Y. Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA. fukunaga@... A totally new autotransfusion system has been developed utilizing a hollow fiber membrane, based upon plasmapheresis technology. Prior to fabricating the system, it was essential to evaluate the basic performance characteristics of the filter, which was designed particularly for the new system. The objective of this study was to prove or disprove that such a system would be available using this filter. An in vitro study was conducted on the filter using bovine blood. The result of the study showed that the filter could process 2-20% of hematocrit blood at a flow rate greater than 250 ml/min of inlet blood continuously. Moreover, it could concentrate 5-20% hematocrit blood to hematocrit percentages greater than 40% by a single passage through the filter. These results seemed to prove that a rapid, continuous, and compact autotransfusion system could be developed using this filter. Br J Surg. 1995 Jun;82(6):765-9. Related Articles, Links Clinical and experimental studies of intraoperative autotransfusion using a new filtration device. Varga ZA, JF, Locke-Edmunds JC, Baird RN, Farndon JR. Department of Surgery, Bristol Royal Infirmary, UK. The Haemocell S-350 device has recently been introduced for intraoperative autotransfusion. The system uses a novel membrane filter to process shed blood. In the first part of this study a 0.2-micron pore size filter was used in a randomized trial comparing the use of autotransfusion (n = 8) with bank blood controls (n = 9) during aortic reconstruction. This part of the trial was abandoned because of unexpected non-surgical bleeding. Bank blood requirements fell from a median of 3.0 (range 0.0-9.0) units to 1.5 (range 0.0-7.0) units when autotransfusion was used, but these patients had a greater perioperative blood loss (1791 (range 932-3104) versus 1140 (range 440-3840) ml). There was evidence of postoperative heparin excess with an activated partial thromboplastin time ratio of 1.3 (range 0.9-3.0) versus 1.0 (range 1.0-1.2) in controls and an activated clotting time of 206 (range 143-280) versus 137 (range 107-142) s. This was confirmed by raised plasma heparin levels and a prolonged thrombin time normalized by protamine. To improve performance a 0.6-micron pore size filter was studied in ten patients. Filtration efficiency doubled from 19 to 38 per cent. Electron micrographs demonstrated better filter clearance, but 44 per cent of the original concentration of heparin remained in the reinfusate. The S-350 device may be an attractive alternative to centrifugation for intraoperative autotransfusion but, until efficiency is improved, it should only be used for cardiovascular surgery when excess heparin can be reversed with protamine. Artif Organs. 2000 Apr;24(4):289-95. Related Articles, Links Development of the membrane autotransfusion system prototype-II: MATS-II. Fukunaga K, Shimoyama T, Sawada K, Sueoka A, Nose Y. Department of Internal Medicine IV, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. This article is the second of a two-part series describing a membrane autotransfusion system, MATS, utilizing plasmapheresis technology. Based on experiences obtained from the first prototype (MATS-I), optimum blood filtration parameters with refined blood and flux pump synchronization were put into an original CPU-board and loaded on a miniaturized, self-operative, and preclinical prototype (MATS-II). This study was conducted to evaluate the MATS-II using diluted blood of various hematocrit concentrations. The results proved that this device could concentrate 4,000-10,000 ml of various hematocrit concentrations into higher than 40% while automatically controlling the flow speed from 250 to 400 ml/min. Also, no significant damage was generated to the red blood cells (RBC). Moreover, the MATS-II salvaged over 90% of platelets together with the RBC. These results suggest that the MATS-II achieves all clinical requirements of an autotransfusion device; it is a continuous hemoconcentration device with minimum damage to cellular components of the blood. Int J Artif Organs. 1998 Dec;21(12):820-4. Related Articles, Links Blood separation with two different autotransfusion devices: effects on blood cell quality and coagulation variables. Rosolski T, Matthey T, Frick U, Hachenberg T. Department of Anesthesiology and Intensive Care Medicine, Ernst-Moritz-Arndt - University, Greifswald - Germany. The quality of blood products obtained from two different autotransfusion devices (CATS- Fresenius and Sequestra 1000 - Medtronic) was tested in 27 patients undergoing elective orthopaedic surgery. Blood products provided from our institutional blood bank (n = 16) served as controls. Hemodiluted blood was separated into platelet poor plasma (PPP), platelet rich plasma (PRP), and packed red cells (PRC) and analysed for blood cell count, fibrinogen concentration, thromboplastin time, partial thromboplastin time, platelet aggregation and platelet recovery rate. Coagulation variables showed no differences between the CATS-group (n = 14) and the Sequestra 1000-group (n = 13). The volume of PRP was lower in the Sequestra 1000-group (45+/-3 ml vs. 89+/-1 ml, p<0.05), but hematocrit was higher (14.4+/-7.8% vs. 8.5+/-2.8%, p<0.05). PPP produced with CATS contained a higher concentration of white blood cells (0.6+/-0.2 Gpt/l vs. 0.1+/-0.01 Gpt/l, p<0.05) and thrombocytes (163+/-74 Gpt/l vs. 11+/-12 Gpt/l, p<0.05). Hematocrit of PRC was significantly higher in the CATS-group (73.8+/-2.0% vs. 69.0+/-6.5%, p<0.05). Blood products were of high quality in both groups and comparable to or superior than blood products provided from our institutional blood bank. Ann Biomed Eng. 2000 Apr;28(4):470-82. Related Articles, Links A simulation study for the design of a control system for the blood concentration process in autotransfusion. Ruggeri A, Comai G, Belloni M, Zanella A. Department of Electronics and Computer Engineering, University of Padova, Italy. ruggeri@... Autotransfusion is the process in which a patient serves as his or her own blood donor; its most important application is the intraoperative blood salvage, in which the blood collected during a surgical operation is filtered, concentrated, washed, and then reinfused. In an automatic autotransfusion device, such as the DIDECO Compact Advanced, red blood cells (RBCs) are separated from the other unwanted components and concentrated by using a rotating bowl and the effect of centrifugal force. An important characteristic of concentrated RBCs is their hematocrit (Hct), i.e., percent RBC volume divided by total blood volume. The aim of this study is to assess the feasibility of a controller, based on the artificial neural network approach, which is able to provide a closed loop control of the hematocrit of the blood in the bowl at the end of the concentration phase. A simulation approach was adopted both for training the network and for assessing its performances. The results obtained are quite satisfactory, since the target Hct was typically reached within a 3% error, and always within 6% in highly challenging situations. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 25, 2004 Report Share Posted September 25, 2004 Having no experience with autotransfusion, I did some searching on the net and found a really good PDF file from Atrium, the makers of a autotransfusion set. " A Personal Guide to Managing Chest Drain Autotransfusions " . There is a local (as opposed to systemic, like heparin) anticoagulant you can add to the collection system to prevent coagulation before retransfusion. Download it from: http://www.atriummed.com/PDF/Red%20Handbook.pdf This site has some interesting links on chest drain education at: http://www.atriummed.com/Products/Chest_Drains/education.asp I have no financial interest in this company. Jim Re: chest darts (Devices) O.K. Who want's to do research of Re-Transfusion devices And figure out price supplier and wich ones would be more appropriate to our practice environments ? Their's a few hints/names of various devices I came across in my search : D E V I C E S J Trauma. 1975 Aug;15(8):663-9. Related Articles, Links Blood availability for the trauma patient-autotransfusion. Mattox KL, LE, Beall AC, Jordan GL. Recovery of intrathoracic and intraperitoneal blood and reinfusion by autotransfusion has been demonstrated to be safe and practical in selected trauma patients. Autotransfusion is ideally applicable to the trauma patient in whom replacement of six or fewer units of blood is required. In addition, autotransfusion provides readily available blood for patients with unusual blood types and for those in whom multiple transfusions may rapidly deplete available stores. The properties of an ideal autotransfusion device include rapid assembly, relatively low cost, ease of operation, in-line filtration, minimized air blood interface, simplified anticoagulation, and safety from air embolism and coagulopathies. Ann Vasc Surg. 1986 May;1(1):131-3. Related Articles, Links Intraoperative autotransfusion with a new disposable system. Imhoff M, Schmidt R, Horsch S. Institute of Anesthesiology, University of Koln, West Germany. In the past 2 years we have used a simple, disposable set for intraoperative autotransfusion. The system consists of a rigid plastic case with a flexible bag inside constituting a 600 ml reservoir which can be connected to any suitable vacuum source. We used it so far in 56 patients undergoing various vascular operations who were autotransfused a total of about 160 units of blood without any complications with regard to blood coagulation or hemolysis. Br J Surg. 1993 Jan;80(1):32-5. Related Articles, Links Comment in: .. Br J Surg. 1993 Aug;80(8):1082. Autotransfusion in aortic surgery: the Haemocell System 350 cell saver. Kalra M, Beech MJ, al-Khaffaf H, worth D. Department of Surgery, University Hospital of South Manchester, UK. Autotransfusion was performed during elective abdominal aortic reconstruction in ten patients using the recently developed Haemocell System 350. A mean of 60 per cent of total blood loss was salvaged, and during operation each patient was autotransfused 1 unit. Good preservation of cellular components, including platelets, was seen after processing with the device, which uses a vortex mixing filter for cell separation. There was no evidence of coagulopathy; mean free plasma haemoglobin levels were slightly raised (17 mg/dl) and plasma heparin concentration was negligible (0.10 units/ml) 4 h after surgery. A transient drop in plasma fibrinogen levels and the appearance of fibrin degradation products in low concentrations (mean 1.5 mg/l) were seen. Oxyhaemoglobin dissociation curves showed the salvaged red blood cells to have a normal affinity for oxygen. Renal and hepatic function remained unaltered and there were no complications attributable to autotransfusion. The device was easy to handle and a trained operator was not required. Obstet Gynecol. 1988 Dec;72(6):947-50. Related Articles, Links A simplified device for intraoperative autotransfusion. Grimes DA. Department of Obstetrics and Gynecology, Women's Hospital, University of Southern California School of Medicine, Los Angeles. Intraoperative autotransfusion, a widely accepted adjunct in many surgical disciplines, has been underused in obstetrics and gynecology. This report describes a new device for autotransfusion that is simpler to operate than traditional systems requiring a technician. The device was used successfully in two obstetric patients with life-threatening intraoperative hemorrhage, one with abdominal pregnancy and the other with postpartum hemorrhage. The patients received autotransfusions of 1700 and 2200 mL, respectively, without incident. Advantages of autotransfusion over banked blood include avoidance of alloimmunization, reduction of transfusion reactions and blood-borne infections, less expense, and acceptance by most religious groups. Disadvantages include potential hemolysis and limited usefulness in the presence of bacterial contamination or malignancy. On balance, the benefits of autotransfusion outweigh the risks. Ugeskr Laeger. 1993 Mar 1;155(9):605-8. Related Articles, Links [solcotrans, a new autotransfusion system] [Article in Danish] Dich Nielsen JO, Skoven A, Henneberg EW, Fasting H. Anaestesi- og karkirurgisk afdeling, Skive Sygehus. Thirty-one patients scheduled to undergo aortic reconstruction were studied. 16 had aortic aneurysms and 15 required aortobifemoral grafts. The solcotrans unit comprises a rigid plastic container with an inner lining bag, into which blood is aspirated. When the bag is full (500 ml), the unit is inverted and blood is re-infused through a 40 micron filter. Sixty-three percent of the blood transfused per-operatively and 41% peri-operatively was given with the solcotrans unit. Only minor changes in the coagulation parameters were seen. Blood cultures from ten solcotrans units were all negative. Two patients contracted pneumonia, and one cystitis. We conclude that the solcotrans system is safe to use when two-to four units of blood are transfused. Further studies are required to define its role when multitransfusions of blood are needed. Anaesthesist. 1983 Nov;32(11):538-44. Related Articles, Links [Autotransfusion with the Sorensen apparatus] [Article in German] Homann B. Since 1980 in Wurzburg the Sorensen autotransfusion unit has been clinically used in 47 patients (35 vascular, 11 trauma patients, one with arterial bleeding after BII, one with aneurysm of the a. pericallosa) and tested to study its practicability, its advantages and disadvantages. Within the laboratory data there was a small decrease of hemoglobin, hematocrit and blood platelets, as well as of the " Quick " and AT-3. PTT and thrombin-time persisted unchanged, as did the results of electrolytes, parameters of renal and liver function, and the status of blood gas analysis. Free hemoglobin i.s. or i.u. was found in three patients with extremely high volume autotransfusions. The autotransfusion unit is convenient, easy to use and reliable. However, it is only suitable for the reinfusion of blood when hemorrhage is moderate and not severe. Hemothorax blood can be used only when adequate anti-fibrinolytic therapy is guaranteed. Nevertheless, the use of the Sorensen autotransfusion unit within the named diagnoses can achieve a precious contribution for saving homologous blood. J Trauma. 1987 May;27(5):537-42. Related Articles, Links Use of the Heimlich valve in a compact autotransfusion device. Schweitzer EJ, Hauer JM, Swan KG, Bresch JR, Harmon JW, Graeber GM. A compact device which evacuates blood from a hemothorax and facilitates rapid autotransfusion was evaluated in dogs. Experimental hemothorax was established surgically by incising the internal mammary artery through a thoracotomy with the animals under general anesthesia. Postoperatively the blood was drained by one of two methods. In the Heimlich valve group (n = 5), blood was drained by a chest tube through a one-way flutter valve into a collapsible plastic bag. In the Sorenson group (n = 5), blood was drained by a chest tube into the Sorenson Autotransfusion System. Blood from these two groups was then autotransfused. In the control group (n = 5), the drained blood was not autotransfused. Results showed no statistical difference between the two autotransfusion groups in the volume of blood collected, circulating fibrinogen levels, platelet counts, stroma-free hemoglobin levels, prothrombin time, or 51Cr-labeled RBC survival. There was a significant drop in the circulating platelet count, which returned to normal by 24 hours, in both groups of dogs which were autotransfused. We conclude that autotransfusion of blood collected by a compact device which utilizes a Heimlich valve and requires no suction is similar to using the Sorenson Autotransfusion System. It may be safe to use the Heimlich valve to collect blood for autotransfusion in clinical situations, where its qualities of simplicity, portability and a minimum requirement for storage space are desirable. Ther Apher. 1999 Feb;3(1):63-8. Related Articles, Links Preliminary evaluation study of a prototype hollow fiber membrane for the continuous membrane autotransfusion system. Fukunaga K, Shimoyama T, Sueoka A, Nose Y. Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA. fukunaga@... A totally new autotransfusion system has been developed utilizing a hollow fiber membrane, based upon plasmapheresis technology. Prior to fabricating the system, it was essential to evaluate the basic performance characteristics of the filter, which was designed particularly for the new system. The objective of this study was to prove or disprove that such a system would be available using this filter. An in vitro study was conducted on the filter using bovine blood. The result of the study showed that the filter could process 2-20% of hematocrit blood at a flow rate greater than 250 ml/min of inlet blood continuously. Moreover, it could concentrate 5-20% hematocrit blood to hematocrit percentages greater than 40% by a single passage through the filter. These results seemed to prove that a rapid, continuous, and compact autotransfusion system could be developed using this filter. Br J Surg. 1995 Jun;82(6):765-9. Related Articles, Links Clinical and experimental studies of intraoperative autotransfusion using a new filtration device. Varga ZA, JF, Locke-Edmunds JC, Baird RN, Farndon JR. Department of Surgery, Bristol Royal Infirmary, UK. The Haemocell S-350 device has recently been introduced for intraoperative autotransfusion. The system uses a novel membrane filter to process shed blood. In the first part of this study a 0.2-micron pore size filter was used in a randomized trial comparing the use of autotransfusion (n = 8) with bank blood controls (n = 9) during aortic reconstruction. This part of the trial was abandoned because of unexpected non-surgical bleeding. Bank blood requirements fell from a median of 3.0 (range 0.0-9.0) units to 1.5 (range 0.0-7.0) units when autotransfusion was used, but these patients had a greater perioperative blood loss (1791 (range 932-3104) versus 1140 (range 440-3840) ml). There was evidence of postoperative heparin excess with an activated partial thromboplastin time ratio of 1.3 (range 0.9-3.0) versus 1.0 (range 1.0-1.2) in controls and an activated clotting time of 206 (range 143-280) versus 137 (range 107-142) s. This was confirmed by raised plasma heparin levels and a prolonged thrombin time normalized by protamine. To improve performance a 0.6-micron pore size filter was studied in ten patients. Filtration efficiency doubled from 19 to 38 per cent. Electron micrographs demonstrated better filter clearance, but 44 per cent of the original concentration of heparin remained in the reinfusate. The S-350 device may be an attractive alternative to centrifugation for intraoperative autotransfusion but, until efficiency is improved, it should only be used for cardiovascular surgery when excess heparin can be reversed with protamine. Artif Organs. 2000 Apr;24(4):289-95. Related Articles, Links Development of the membrane autotransfusion system prototype-II: MATS-II. Fukunaga K, Shimoyama T, Sawada K, Sueoka A, Nose Y. Department of Internal Medicine IV, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. This article is the second of a two-part series describing a membrane autotransfusion system, MATS, utilizing plasmapheresis technology. Based on experiences obtained from the first prototype (MATS-I), optimum blood filtration parameters with refined blood and flux pump synchronization were put into an original CPU-board and loaded on a miniaturized, self-operative, and preclinical prototype (MATS-II). This study was conducted to evaluate the MATS-II using diluted blood of various hematocrit concentrations. The results proved that this device could concentrate 4,000-10,000 ml of various hematocrit concentrations into higher than 40% while automatically controlling the flow speed from 250 to 400 ml/min. Also, no significant damage was generated to the red blood cells (RBC). Moreover, the MATS-II salvaged over 90% of platelets together with the RBC. These results suggest that the MATS-II achieves all clinical requirements of an autotransfusion device; it is a continuous hemoconcentration device with minimum damage to cellular components of the blood. Int J Artif Organs. 1998 Dec;21(12):820-4. Related Articles, Links Blood separation with two different autotransfusion devices: effects on blood cell quality and coagulation variables. Rosolski T, Matthey T, Frick U, Hachenberg T. Department of Anesthesiology and Intensive Care Medicine, Ernst-Moritz-Arndt - University, Greifswald - Germany. The quality of blood products obtained from two different autotransfusion devices (CATS- Fresenius and Sequestra 1000 - Medtronic) was tested in 27 patients undergoing elective orthopaedic surgery. Blood products provided from our institutional blood bank (n = 16) served as controls. Hemodiluted blood was separated into platelet poor plasma (PPP), platelet rich plasma (PRP), and packed red cells (PRC) and analysed for blood cell count, fibrinogen concentration, thromboplastin time, partial thromboplastin time, platelet aggregation and platelet recovery rate. Coagulation variables showed no differences between the CATS-group (n = 14) and the Sequestra 1000-group (n = 13). The volume of PRP was lower in the Sequestra 1000-group (45+/-3 ml vs. 89+/-1 ml, p<0.05), but hematocrit was higher (14.4+/-7.8% vs. 8.5+/-2.8%, p<0.05). PPP produced with CATS contained a higher concentration of white blood cells (0.6+/-0.2 Gpt/l vs. 0.1+/-0.01 Gpt/l, p<0.05) and thrombocytes (163+/-74 Gpt/l vs. 11+/-12 Gpt/l, p<0.05). Hematocrit of PRC was significantly higher in the CATS-group (73.8+/-2.0% vs. 69.0+/-6.5%, p<0.05). Blood products were of high quality in both groups and comparable to or superior than blood products provided from our institutional blood bank. Ann Biomed Eng. 2000 Apr;28(4):470-82. Related Articles, Links A simulation study for the design of a control system for the blood concentration process in autotransfusion. Ruggeri A, Comai G, Belloni M, Zanella A. Department of Electronics and Computer Engineering, University of Padova, Italy. ruggeri@... Autotransfusion is the process in which a patient serves as his or her own blood donor; its most important application is the intraoperative blood salvage, in which the blood collected during a surgical operation is filtered, concentrated, washed, and then reinfused. In an automatic autotransfusion device, such as the DIDECO Compact Advanced, red blood cells (RBCs) are separated from the other unwanted components and concentrated by using a rotating bowl and the effect of centrifugal force. An important characteristic of concentrated RBCs is their hematocrit (Hct), i.e., percent RBC volume divided by total blood volume. The aim of this study is to assess the feasibility of a controller, based on the artificial neural network approach, which is able to provide a closed loop control of the hematocrit of the blood in the bowl at the end of the concentration phase. A simulation approach was adopted both for training the network and for assessing its performances. The results obtained are quite satisfactory, since the target Hct was typically reached within a 3% error, and always within 6% in highly challenging situations. Member Information: List owner: Ian Sharpe Owner@... Editor: Ross Boardman Editor@... ALL list admin messages (subscriptions & unsubscriptions) should be sent to the list owner. Post message: egroups Please visit our website http://www.remotemedics.co.uk Regards The Remote Medics Team Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 26, 2004 Report Share Posted September 26, 2004 --- Dawdy <jdawdy@...> wrote: > Having no experience with autotransfusion, I did some searching on > the net and found a really good PDF file from Atrium, the makers of > a autotransfusion set. " A Personal Guide to Managing Chest Drain > Autotransfusions " . > > Jim > W O W ! Excellent site Good training and product support But I can't help noticing how bulky and breakable the equipment appears... So I've looked a bit further and found : http://www.vitaid.com/usa/celltrans/ http://www.vitaid.com/usa/celltrans/CellTransBrochure.pdf & http://www.sigroupplc.com/haemocell-index1.html Also Another article in PreHosp AutoTransfusion : Chest, Vol 93, 522-526, Copyright © 1988 by American College of Chest Physicians Prehospital autotransfusion in life-threatening hemothorax P Barriot, B Riou and P Viars Service de Sante de la Brigade des Sapeurs Pompiers de Paris, France. Eighteen patients with life-threatening traumatic hemothorax received prehospital autotransfusion using a simple new device. During transfer to the hospital, they received 3.9 +/- 0.5 L of colloid fluid and 4.1 +/- 0.6 L of autotransfused blood, without anticoagulation. Hemorrhagic blood was not coagulable, had a hematocrit of 20 +/- 4 percent, few platelets, and low fibrinogen levels. Five patients died from irreversible hemorrhagic shock. Thirteen patients were alive upon admission to the hospital, underwent emergency surgery, and were discharged alive. During autotransfusion, hematocrit decreased from 24 +/- 3 to 19 +/- 3 percent, and systolic arterial pressure increased from 78 +/- 11 to 88 +/- 12 mm Hg. Upon admission to the hospital, platelet count was 90,800 +/- 21,400/cu mm, prothrombin time 48 +/- 3 percent, partial thromboplastin time 197 +/- 18 percent, plasma free hemoglobin levels 21 +/- 7 mg/100 ml, and serum potassium levels 3.6 +/- 0.5 mmol/L. No serious complication could be related to autotransfusion considered to be crucial to patients' survival. The preliminary results of this study suggest that autotransfusion might be developed in the prehospital setting since it appears simple and safe, and represents the only hope of survival for patients with life-threatening hemothorax. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 28, 2004 Report Share Posted September 28, 2004 Hey - My partner today, Cusson, says hello. He saw your name on the post about capnography, as I printed it and posted it in the station. We use both ETCO and SaO2 via a ProPaq in all of our helicopters. He will look you up when he goes back to Montreal later this year. Cheers Jerry RE: chest darts (Devices) --- Dawdy <jdawdy@...> wrote: > Having no experience with autotransfusion, I did some searching on the > net and found a really good PDF file from Atrium, the makers of a > autotransfusion set. " A Personal Guide to Managing Chest Drain > Autotransfusions " . > > Jim > W O W ! Excellent site Good training and product support But I can't help noticing how bulky and breakable the equipment appears... So I've looked a bit further and found : http://www.vitaid.com/usa/celltrans/ http://www.vitaid.com/usa/celltrans/CellTransBrochure.pdf & http://www.sigroupplc.com/haemocell-index1.html Also Another article in PreHosp AutoTransfusion : Chest, Vol 93, 522-526, Copyright C 1988 by American College of Chest Physicians Prehospital autotransfusion in life-threatening hemothorax P Barriot, B Riou and P Viars Service de Sante de la Brigade des Sapeurs Pompiers de Paris, France. Eighteen patients with life-threatening traumatic hemothorax received prehospital autotransfusion using a simple new device. During transfer to the hospital, they received 3.9 +/- 0.5 L of colloid fluid and 4.1 +/- 0.6 L of autotransfused blood, without anticoagulation. Hemorrhagic blood was not coagulable, had a hematocrit of 20 +/- 4 percent, few platelets, and low fibrinogen levels. Five patients died from irreversible hemorrhagic shock. Thirteen patients were alive upon admission to the hospital, underwent emergency surgery, and were discharged alive. During autotransfusion, hematocrit decreased from 24 +/- 3 to 19 +/- 3 percent, and systolic arterial pressure increased from 78 +/- 11 to 88 +/- 12 mm Hg. Upon admission to the hospital, platelet count was 90,800 +/- 21,400/cu mm, prothrombin time 48 +/- 3 percent, partial thromboplastin time 197 +/- 18 percent, plasma free hemoglobin levels 21 +/- 7 mg/100 ml, and serum potassium levels 3.6 +/- 0.5 mmol/L. No serious complication could be related to autotransfusion considered to be crucial to patients' survival. The preliminary results of this study suggest that autotransfusion might be developed in the prehospital setting since it appears simple and safe, and represents the only hope of survival for patients with life-threatening hemothorax. Member Information: List owner: Ian Sharpe Owner@... Editor: Ross Boardman Editor@... ALL list admin messages (subscriptions & unsubscriptions) should be sent to the list owner. Post message: egroups Please visit our website http://www.remotemedics.co.uk Regards The Remote Medics Team Quote Link to comment Share on other sites More sharing options...
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