Guest guest Posted October 18, 2004 Report Share Posted October 18, 2004 Can anyone give me credible sites on Flumist and the dangers it poses to immunocompromised people and the population in general? My husbands work did flu shots a couple weeks ago and announced today that they would be doing Flumist on Thurs/Friday. I am not happy about this and my husband emailed someone at his work about it and of course they said it was safe, if it wasn't the dept of health wouldn't allow them to use it: rolling eyes::: I told him to tell them to just pull the insert and look under precautions but not sure if that is going to work. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 18, 2004 Report Share Posted October 18, 2004 At 11:09 PM 10/18/2004 -0000, you wrote: > > >Can anyone give me credible sites on Flumist and the dangers it poses >to immunocompromised people and the population in general? My husbands >work did flu shots a couple weeks ago and announced today that they >would be doing Flumist on Thurs/Friday. I am not happy about this and >my husband emailed someone at his work about it and of course they >said it was safe, if it wasn't the dept of health wouldn't allow them >to use it: rolling eyes::: I told him to tell them to just pull the >insert and look under precautions but not sure if that is going to work. > > I have POSTED tons - is anyone reading anythinng I post? I will post it again -------------------------------------------------------- Sheri Nakken, R.N., MA, Classical Homeopath Vaccination Information & Choice Network, Nevada City CA & Wales UK $$ Donations to help in the work - accepted by Paypal account vaccineinfo@... voicemail US 530-740-0561 (go to http://www.paypal.com) or by mail Vaccines - http://www.nccn.net/~wwithin/vaccine.htm Vaccine Dangers On-Line course - http://www.nccn.net/~wwithin/vaccineclass.htm Homeopathy On-Line course - http://www.nccn.net/~wwithin/homeo.htm ANY INFO OBTAINED HERE NOT TO BE CONSTRUED AS MEDICAL OR LEGAL ADVICE. THE DECISION TO VACCINATE IS YOURS AND YOURS ALONE. ****** " Just look at us. Everything is backwards; everything is upside down. Doctors destroy health, lawyers destroy justice, universities destroy knowledge, governments destroy freedom, the major media destroy information and religions destroy spirituality " .... Ellner Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 18, 2004 Report Share Posted October 18, 2004 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi? cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=15034829 Clin Infect Dis. 2004 Apr 1;38(7):974-80. Epub 2004 Mar 15. Related Articles, Links Intranasal influenza vaccine in a working population. Sendi P, Locher R, Bucheli B, Battegay M. Division of Infectious Diseases, Basel University Hospital, Basel, Switzerland. In the present study, we assessed the incidence of adverse events and influenza-like symptoms in a working population in Switzerland that was vaccinated against influenza. A total of 12,582 individuals of working age (<65 years old) were offered a free influenza vaccine of their choice (injectable or intranasal vaccine) in October and November 2000. Of these individuals, 1600 were vaccinated against influenza. Ninety-seven percent of the vaccine recipients chose the intranasal vaccine, and 3% chose the injectable influenza vaccine. The incidence of influenza-like symptoms and side effects was 13% and 36%, respectively. Individuals who chose the intranasal vaccine were more likely to report side effects (OR, 3.23; 95% CI, 1.29-8.08). Facial paralysis was observed in 11 patients and was the most severe adverse event associated with the intranasal influenza vaccine. As a result of these adverse events, the intranasal vaccine was removed from the market in the fall of 2001. PMID: 15034829 [PubMed - indexed for MEDLINE FluMist - MedImmune http://www.flumist.com/pdf/prescribinginfo.pdf CONTRAINDICATIONS Under no circumstances should FluMist® be administered parenterally. Individuals with a history of hypersensitivity, especially anaphylactic reactions, to any component of FluMist, including eggs or egg products, should not receive FluMist (see DESCRIPTION). FluMist is contraindicated in children and adolescents (5-17 years of age) receiving aspirin therapy or aspirin-containing therapy, because of the association of Reye syndrome with aspirin and wild-type influenza infection. FluMist should not be administered to individuals who have a history of Guillain-Barré syndrome. As with other live virus vaccines, FluMist should not be administered to individuals with known or suspected immune deficiency diseases such as combined immunodeficiency, agammaglobulinemia, and thymic abnormalities and conditions such as human immunodeficiency virus infection, malignancy, leukemia, or lymphoma. FluMist is also contraindicated in patients who may be immunosuppressed or have altered or compromised immune status as a consequence of treatment with systemic corticosteroids, alkylating drugs, antimetabolites, radiation, or other immunosuppressive therapies. WARNINGS The safety of FluMist in individuals with asthma or reactive airways disease has not been established. In a large safety study in children 1-17 years of age, children <5 years of age who received FluMist were found to have an increased rate of asthma within 42 days of vaccination when compared to placebo recipients (see ADVERSE REACTIONS). FluMist should not be administered to individuals with a history of asthma or reactive airways disease. The safety of FluMist in individuals with underlying medical conditions that may predispose them to severe disease following wild- type influenza infection has not been established. FluMist is not indicated for these individuals. High-risk individuals include, but are not limited to, adults and children with chronic disorders of the cardiovascular and pulmonary systems, including asthma; pregnant women; adults and children who required regular medical follow-up or hospitalization during the preceding year because of chronic metabolic diseases (including diabetes), renal dysfunction, or hemoglobinopathies; and adults and children with congenital or acquired immunosuppression caused by underlying disease or immunosuppressive therapy (see CONTRAINDICATIONS). Intramuscularly administered inactivated influenza vaccines are available to immunize high-risk individuals [1]. As with any vaccine, FluMist may not protect 100% of individuals receiving the vaccine. Prior to administration of FluMist, individuals or their parent/guardian should be asked about their current health status and their personal medical history, including immune status, to determine the existence of any contraindications to immunization with FluMist (see CONTRAINDICATIONS and WARNINGS). FluMist recipients should avoid close contact (e.g., within the same household) with immunocompromised individuals for at least 21 days.EPINEPHRINE INJECTION (1:1000) OR COMPARABLE TREATMENT MUST BE READILY AVAILABLE IN THE EVENT OF AN ACUTE ANAPHYLACTIC REACTION FOLLOWING VACCINATION. The health care provider should ensure prevention of any allergic or other adverse reactions by reviewing the individual's history for possible sensitivity to influenza vaccine components, including eggs and egg products. Administration of FluMist should be postponed until after the acute phase (at least 72 hours) of febrile and/or respiratory illnesses. Information for Vaccine Recipients or Parents/Guardians Vaccine recipients or their parents/guardians should be informed by the health care provider of the potential benefits and risks of FluMist, and the need for two doses for the first use of FluMist in 5-8 year olds. Due to the possible transmission of vaccine virus, vaccine recipients or their parents/guardians should be advised that vaccine recipients should avoid close contact (e.g., within the same household) with immunocompromised individuals for at least 21 days. The vaccine recipient or the parent/guardian accompanying the vaccine recipient should be told to report any suspected adverse events to the physician or clinic where the vaccine was administered (see ADVERSE EVENT REPORTING). Concurrent Administration with Other Vaccines The safety and immunogenicity of FluMist when administered concurrently with other vaccines have not been determined. Therefore, FluMist should not be administered concurrently with other vaccines. Studies of FluMist in healthy individuals excluded subjects who received any live virus vaccine within one month of enrollment and any inactivated or subunit vaccine within two weeks of enrollment; therefore, health care providers should adhere to these intervals when administering FluMist. Laboratory Interactions Data related to the length of time that FluMist can be recovered from nasal specimens of children and adults are limited. Nasopharyngeal secretions or swabs collected from vaccinees may test positive for influenza virus for up to three weeks. Carcinogenesis, Mutagenesis, Impairment of Fertility FluMist has not been evaluated for its carcinogenic or mutagenic potential or its potential to impair fertility. FluMist contains live attenuated influenza viruses that must infect and replicate in cells lining the nasopharynx of the recipient to induce immunity. Vaccine viruses capable of infection and replication can be cultured from nasal secretions obtained from vaccine recipients. The relationship of viral replication in a vaccine recipient and transmission of vaccine viruses to other individuals has not been established. A prospective, randomized, double-blind, placebo-controlled trial in a daycare setting in children less than three years of age was performed with the primary objective of assessing the probability that vaccine viruses will be transmitted from a vaccinated individual to a non-vaccinated individual [17]. Children enrolled in the study attended daycare at least three days per week for four hours per day, and were in a playroom with at least four children, at least one of whom was vaccinated with FluMist. A total of 197 children 8-36 months of age were randomized to receive one dose of FluMist (n=98) or placebo (n=99). Virus shedding was evaluated for 21 days by culture of nasal swab specimens obtained from each subject approximately three times per week. Wild-type A (H3N2) influenza virus was documented to have circulated in the community and in the study population during the trial, whereas Type A (H1N1) and Type B strains did not. At least one vaccine strain was isolated from 80% of FluMist recipients. Viruses were recovered from specimens obtained over a range of 1-21 days (mean duration of 7.6 days ± 3.4 days). The cold-adapted (ca) and temperature-sensitive (ts) phenotypes were preserved in all recovered viruses tested (n=135 tested of 250 strains isolated at the local laboratory). Ten influenza isolates were cultured from a total of seven placebo subjects. One placebo subject became infected with a Type B virus confirmed as a transmitted vaccine virus by a FluMist recipient in the same playgroup. Of the 11 nasal swabs obtained from the subject on Days 0-21, vaccine virus was cultured only from the Day 15 specimen. This Type B isolate retained the ca, ts, and att phenotypes of the vaccine strain, and had the same genetic sequence when compared to a Type B virus cultured from a vaccine recipient within the same playgroup. This placebo recipient experienced cough, coryza, and irritability similar to the symptoms observed among some FluMist vaccinees in the trial. No viruses were cultured from any of the other placebo recipients in this playgroup. Nine isolates identified as Type A were cultured from six placebo subjects; two of these subjects had two cultures that grew Type A strains (four isolates) confirmed as wild-type A/Panama H3N2). Type A isolates that could not be further characterized were cultured from the four remaining placebo subjects; because the isolates could not be further characterized, the possibility that they were vaccine strains could not be excluded. > > Can anyone give me credible sites on Flumist and the dangers it poses > to immunocompromised people and the population in general? My husbands > work did flu shots a couple weeks ago and announced today that they > would be doing Flumist on Thurs/Friday. I am not happy about this and > my husband emailed someone at his work about it and of course they > said it was safe, if it wasn't the dept of health wouldn't allow them > to use it: rolling eyes::: I told him to tell them to just pull the > insert and look under precautions but not sure if that is going to work. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 18, 2004 Report Share Posted October 18, 2004 I appologize for asking again:( I have company in from out of town and needed the info fast. there is so much flu stuff on list it would take forever. Again, I appologize, I will make sure next time to have time to do my own searches. > > > > > >Can anyone give me credible sites on Flumist and the dangers it poses > >to immunocompromised people and the population in general? My husbands > >work did flu shots a couple weeks ago and announced today that they > >would be doing Flumist on Thurs/Friday. I am not happy about this and > >my husband emailed someone at his work about it and of course they > >said it was safe, if it wasn't the dept of health wouldn't allow them > >to use it: rolling eyes::: I told him to tell them to just pull the > >insert and look under precautions but not sure if that is going to work. > > > > > > I have POSTED tons - is anyone reading anythinng I post? > I will post it again > -------------------------------------------------------- > Sheri Nakken, R.N., MA, Classical Homeopath > Vaccination Information & Choice Network, Nevada City CA & Wales UK > $$ Donations to help in the work - accepted by Paypal account > vaccineinfo@t... voicemail US 530-740-0561 > (go to http://www.paypal.com) or by mail > Vaccines - http://www.nccn.net/~wwithin/vaccine.htm > Vaccine Dangers On-Line course - http://www.nccn.net/~wwithin/vaccineclass.htm > Homeopathy On-Line course - http://www.nccn.net/~wwithin/homeo.htm > ANY INFO OBTAINED HERE NOT TO BE CONSTRUED AS MEDICAL > OR LEGAL ADVICE. THE DECISION TO VACCINATE IS YOURS AND YOURS ALONE. > > ****** > " Just look at us. Everything is backwards; everything is upside down. > Doctors destroy health, lawyers destroy justice, universities destroy > knowledge, governments destroy freedom, the major media destroy information > and religions destroy spirituality " .... Ellner Quote Link to comment Share on other sites More sharing options...
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