Re: Immunoglobulin Test results

[Guest guest]

Hi Sue,

I too had this test, and it was normal.

(At that time I was reacting to all kinds of stuff, from orange juice to new

plastic.)

Ron

Message 5

From: " Sue T " morabshadow@...

Date: Sat May 27, 2006 8:34pm(PDT)

Subject: Immunoglobulin Test results

Hi Rich and All,

My infectious disease doc ran some immunoglobulin

testing.

Can anyone give me an idea what this may mean to me in

regards to my

CFS, Lyme, and heavy metal toxicity even though the

results seems to be

in the normal to high normal range?

Would it better to have them in low

normal . . . I don't have a clue?

immunoglobulin IGA 253 mg/dl range 40-375

immunoglobulin IGG 1,160 mg/dl range 600-1,500

immunoglobulin IGM 133 mg/dl range 30-190

Thanks a bunch!

Sue T

__________________________________________________

[Guest guest]

janet,

how did you raise your nk cells?

thanks,

jim

jgstev716@... writes:

> I raised my killer cells and that stopped

[Guest guest]

Hi Sue T, you bring up a good question. I have autoimmune antibodies

and one infection after another, but my immunoglobulin test results

are normal. I have never understood why this is the case. I hope

someone can shed some light on this for me too.

Better health,

Vickie

>

> Hi Rich and All,

>

> My infectious disease doc ran some immunoglobulin testing.

>

> Can anyone give me an idea what this may mean to me in regards to

my

> CFS, Lyme, and heavy metal toxicity even though the results seems

to be

> in the normal to high normal range?

>

> Would it better to have them in low

> normal . . . I don't have a clue?

>

> immunoglobulin IGA 253 mg/dl range 40-375

>

> immunoglobulin IGG 1,160 mg/dl range 600-1,500

>

> immunoglobulin IGM 133 mg/dl range 30-190

>

> Thanks a bunch!

> Sue T

>

[Guest guest]

Vickie,

Are you also testing for killer cell activity???

Janet

in San Diego

Vickie <vickie77077@...> wrote:

Hi Sue T, you bring up a good question. I have autoimmune antibodies

and one infection after another, but my immunoglobulin test results

are normal. I have never understood why this is the case. I hope

someone can shed some light on this for me too.

Better health,

Vickie

>

> Hi Rich and All,

>

> My infectious disease doc ran some immunoglobulin testing.

>

> Can anyone give me an idea what this may mean to me in regards to

my

> CFS, Lyme, and heavy metal toxicity even though the results seems

to be

> in the normal to high normal range?

>

> Would it better to have them in low

> normal . . . I don't have a clue?

>

> immunoglobulin IGA 253 mg/dl range 40-375

>

> immunoglobulin IGG 1,160 mg/dl range 600-1,500

>

> immunoglobulin IGM 133 mg/dl range 30-190

>

> Thanks a bunch!

> Sue T

>

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

[Guest guest]

My killer cell activity is extremely low. Are you saying that my

immunoglobulin results are normal because of T2 upregulation and T1

downregulation?

Vickie

>Janet s <jgstev716@...> wrote:

>

> Vickie,

>

> Are you also testing for killer cell activity???

>

> Janet

> in San Diego

>

> Vickie <vickie77077@...> wrote:

> Hi Sue T, you bring up a good question. I have autoimmune

antibodies

> and one infection after another, but my immunoglobulin test results

> are normal. I have never understood why this is the case. I hope

> someone can shed some light on this for me too.

>

> Better health,

>

> Vickie

>

>

> >

> > Hi Rich and All,

> >

> > My infectious disease doc ran some immunoglobulin testing.

> >

> > Can anyone give me an idea what this may mean to me in regards to

> my

> > CFS, Lyme, and heavy metal toxicity even though the results seems

> to be

> > in the normal to high normal range?

> >

> > Would it better to have them in low

> > normal . . . I don't have a clue?

> >

> > immunoglobulin IGA 253 mg/dl range 40-375

> >

> > immunoglobulin IGG 1,160 mg/dl range 600-1,500

> >

> > immunoglobulin IGM 133 mg/dl range 30-190

> >

> > Thanks a bunch!

> > Sue T

> >

>

>

>

>

>

>

> This list is intended for patients to share personal experiences

with each other, not to give medical advice. If you are interested

in any treatment discussed here, please consult your doctor.

>

>

>

>

[Guest guest]

HI Vickie,

The reason I asked is I was getting everything that came around. Colds, flu,

etc. I raised my killer cells and that stopped.

Janet

in San Diego

Vickie <vickie77077@...> wrote:

My killer cell activity is extremely low. Are you saying that my

immunoglobulin results are normal because of T2 upregulation and T1

downregulation?

Vickie

>Janet s <jgstev716@...> wrote:

>

> Vickie,

>

> Are you also testing for killer cell activity???

>

> Janet

> in San Diego

>

> Vickie <vickie77077@...> wrote:

> Hi Sue T, you bring up a good question. I have autoimmune

antibodies

> and one infection after another, but my immunoglobulin test results

> are normal. I have never understood why this is the case. I hope

> someone can shed some light on this for me too.

>

> Better health,

>

> Vickie

>

>

> >

> > Hi Rich and All,

> >

> > My infectious disease doc ran some immunoglobulin testing.

> >

> > Can anyone give me an idea what this may mean to me in regards to

> my

> > CFS, Lyme, and heavy metal toxicity even though the results seems

> to be

> > in the normal to high normal range?

> >

> > Would it better to have them in low

> > normal . . . I don't have a clue?

> >

> > immunoglobulin IGA 253 mg/dl range 40-375

> >

> > immunoglobulin IGG 1,160 mg/dl range 600-1,500

> >

> > immunoglobulin IGM 133 mg/dl range 30-190

> >

> > Thanks a bunch!

> > Sue T

> >

>

>

>

>

>

>

> This list is intended for patients to share personal experiences

with each other, not to give medical advice. If you are interested

in any treatment discussed here, please consult your doctor.

>

>

>

>

[Guest guest]

HI Jim,

I use Moducare whicfh helps the body move from TH2 to TH1 (killer cells), IP-6

and I still have some MGN-3. I used all three for while. Then I worked down into

a maintenance level

Janet

in San Diego.

jschm111@... wrote:

janet,

how did you raise your nk cells?

thanks,

jim

jgstev716@... writes:

> I raised my killer cells and that stopped

[Guest guest]

Sue,

Looks pretty normal to me, mine are similar. You can request he/she

run the subclasses to see if there is a deficiency within each class.

Terry

>

> Hi Rich and All,

>

> My infectious disease doc ran some immunoglobulin testing.

>

> Can anyone give me an idea what this may mean to me in regards to

my

> CFS, Lyme, and heavy metal toxicity even though the results seems

to be

> in the normal to high normal range?

>

> Would it better to have them in low

> normal . . . I don't have a clue?

>

> immunoglobulin IGA 253 mg/dl range 40-375

>

> immunoglobulin IGG 1,160 mg/dl range 600-1,500

>

> immunoglobulin IGM 133 mg/dl range 30-190

>

> Thanks a bunch!

> Sue T

>

[Guest guest]

Janet, how did you raise your natural killer cells? At this point, I

would do ANYTHING to improve my immune functioning. I have ordered

some new supplements based on my Amy Yasko gene test results, but

they have not arrived yet.

I have had an absolutely ghastly two or three weeks. I caught stomach

flu from Hell from my husband. My case of it was 3 times worse than

his. I still have lingering effects from it. I have developed chronic

reflux -- (but not acid reflux). My food just backs up into my

esophagus after I eat. There is no pain, but I can feel it backing

up, and then I belch a lot or feel nauseated.

In an effort to get the diarhea under control, I went too far in the

other direction and my bowel became impacted. If I had any faith in

the emergency rooms in this city, I would have gone. My hemorroids

bled and then became swollen and infected. Normally I don't have

problems with hemorroids. Then I came down with a very painful

bladder infection. Sorry to be so graphic. I just had to vent my pain

and frustration.

My husband, with his normal immune system, didn't have all these

problems. ARGH!!

Vickie

> > >

> > > Hi Rich and All,

> > >

> > > My infectious disease doc ran some immunoglobulin testing.

> > >

> > > Can anyone give me an idea what this may mean to me in regards

to

> > my

> > > CFS, Lyme, and heavy metal toxicity even though the results

seems

> > to be

> > > in the normal to high normal range?

> > >

> > > Would it better to have them in low

> > > normal . . . I don't have a clue?

> > >

> > > immunoglobulin IGA 253 mg/dl range 40-375

> > >

> > > immunoglobulin IGG 1,160 mg/dl range 600-1,500

> > >

> > > immunoglobulin IGM 133 mg/dl range 30-190

> > >

> > > Thanks a bunch!

> > > Sue T

> > >

> >

> >

> >

> >

> >

> >

> > This list is intended for patients to share personal experiences

> with each other, not to give medical advice. If you are interested

> in any treatment discussed here, please consult your doctor.

> >

> >

> >

> >

[Guest guest]

HI Vicki,

I am fairly new to this group, but my gut feeling after reading and doing some

extensive reseach of my own is that Amy Yaskow is on the right track. I am

waiting for my genetic tests to come back. I think it is our " terrain " and not a

specific " bug " .

I used Moducare (it shifts the body from TH2 to TH1, IP-6 and I also had some

MGN-3 which I also used. One supplement I don't see referred to often here is

larch arabinogalactans, known as Arabinex. It raises killer cells and also other

parts of the immune system. Google it. I used all of these for awhile. I had

that " stomach flu from hell " and also got sick with everything going around.

That has stopped for me.

Get well soon and let me know how your are doing.

Janet

in San Diego

Vickie <vickie77077@...> wrote:

Janet, how did you raise your natural killer cells? At this point, I

would do ANYTHING to improve my immune functioning. I have ordered

some new supplements based on my Amy Yasko gene test results, but

they have not arrived yet.

I have had an absolutely ghastly two or three weeks. I caught stomach

flu from Hell from my husband. My case of it was 3 times worse than

his. I still have lingering effects from it. I have developed chronic

reflux -- (but not acid reflux). My food just backs up into my

esophagus after I eat. There is no pain, but I can feel it backing

up, and then I belch a lot or feel nauseated.

In an effort to get the diarhea under control, I went too far in the

other direction and my bowel became impacted. If I had any faith in

the emergency rooms in this city, I would have gone. My hemorroids

bled and then became swollen and infected. Normally I don't have

problems with hemorroids. Then I came down with a very painful

bladder infection. Sorry to be so graphic. I just had to vent my pain

and frustration.

My husband, with his normal immune system, didn't have all these

problems. ARGH!!

Vickie

> > >

> > > Hi Rich and All,

> > >

> > > My infectious disease doc ran some immunoglobulin testing.

> > >

> > > Can anyone give me an idea what this may mean to me in regards

to

> > my

> > > CFS, Lyme, and heavy metal toxicity even though the results

seems

> > to be

> > > in the normal to high normal range?

> > >

> > > Would it better to have them in low

> > > normal . . . I don't have a clue?

> > >

> > > immunoglobulin IGA 253 mg/dl range 40-375

> > >

> > > immunoglobulin IGG 1,160 mg/dl range 600-1,500

> > >

> > > immunoglobulin IGM 133 mg/dl range 30-190

> > >

> > > Thanks a bunch!

> > > Sue T

> > >

> >

> >

> >

> >

> >

> >

> > This list is intended for patients to share personal experiences

> with each other, not to give medical advice. If you are interested

> in any treatment discussed here, please consult your doctor.

> >

> >

> >

> >

[Guest guest]

vicki,

what doses of ip-6 and moducare have you taken? know of any research or

references on them?

thanks,

jim

[Guest guest]

Hi, Sue.

Sorry for the slow response. We've been working on our house

lately, and I haven't had much time to respond to emails.

I think that the most that can be said from your immunoglobulin

class measurements is that you don't have an immune deficiency in

your humoral (antibody-related) immune response. I think this is

consistent with what is generally found to be true in CFS. The

problems in the immune system in CFS are primarily in the cell-

mediated immune response (involving the T cells). That's why yeast,

viral and intracellular bacterial infections are the main ones

encountered. These types of infections require a healthy cell-

mediated immune response to defeat them. As you probably know, the

Lyme disease causing bacteria are able to assume an intracellular

form.

In the past, I attributed the problems in the Th1 and killer-T cell-

mediated immune response to glutathione depletion. I still believe

that is a major factor, but in addition, based on the work of Amy

Yasko, I now suspect that the blocks in the folate metabolism that

are linked to the methylation cycle block also contribute to the

problems with the cell-mediated immune response in CFS. Folate is

needed to make new DNA and RNA, and these are needed in large

amounts to allow the T cells to proliferate (clone themselves),

which is needed for an effective cell-mediated immune response. So

now I believe that the cell-mediated immunity is suppressed by both

these factors when there is a vicious circle that involves both a

block in the methylation cycle and a depletion of glutathione. I

think that to restore proper function of the cell-mediated immunity,

it is necessary to correct the methylation/folate cycles block, as

well as to restore the level of glutathione. These are linked

together.

Rich

>

> Hi Rich and All,

>

> My infectious disease doc ran some immunoglobulin testing.

>

> Can anyone give me an idea what this may mean to me in regards to

my

> CFS, Lyme, and heavy metal toxicity even though the results seems

to be

> in the normal to high normal range?

>

> Would it better to have them in low

> normal . . . I don't have a clue?

>

> immunoglobulin IGA 253 mg/dl range 40-375

>

> immunoglobulin IGG 1,160 mg/dl range 600-1,500

>

> immunoglobulin IGM 133 mg/dl range 30-190

>

> Thanks a bunch!

> Sue T

>

[Guest guest]

Hi Rich,

Thanks again for your time and explaination. These particular tests are just a

portion of the tests I had run at Kaiser lately. I had some T-cell tests run and

when I receive the results I will scan them ans send them to you. For instance

my CD4 is 52% range 30-60 and CD8 was 28% range 11-37. The only one I saw out

of range was the CD3 82% range 68-80.

Have a great weekend and I will be sending you more of a report of how I am

improving in a week or so.

I am riding horses again a little, but my main problemfor the moment I

believe is my adrenals. I will be addressing that very soon with your

recommendations.

Cheers!

Sue

rvankonynen <richvank@...> wrote:

Hi, Sue.

Sorry for the slow response. We've been working on our house

lately, and I haven't had much time to respond to emails.

I think that the most that can be said from your immunoglobulin

class measurements is that you don't have an immune deficiency in

your humoral (antibody-related) immune response. I think this is

consistent with what is generally found to be true in CFS. The

problems in the immune system in CFS are primarily in the cell-

mediated immune response (involving the T cells). That's why yeast,

viral and intracellular bacterial infections are the main ones

encountered. These types of infections require a healthy cell-

mediated immune response to defeat them. As you probably know, the

Lyme disease causing bacteria are able to assume an intracellular

form.

In the past, I attributed the problems in the Th1 and killer-T cell-

mediated immune response to glutathione depletion. I still believe

that is a major factor, but in addition, based on the work of Amy

Yasko, I now suspect that the blocks in the folate metabolism that

are linked to the methylation cycle block also contribute to the

problems with the cell-mediated immune response in CFS. Folate is

needed to make new DNA and RNA, and these are needed in large

amounts to allow the T cells to proliferate (clone themselves),

which is needed for an effective cell-mediated immune response. So

now I believe that the cell-mediated immunity is suppressed by both

these factors when there is a vicious circle that involves both a

block in the methylation cycle and a depletion of glutathione. I

think that to restore proper function of the cell-mediated immunity,

it is necessary to correct the methylation/folate cycles block, as

well as to restore the level of glutathione. These are linked

together.

Rich

>

> Hi Rich and All,

>

> My infectious disease doc ran some immunoglobulin testing.

>

> Can anyone give me an idea what this may mean to me in regards to

my

> CFS, Lyme, and heavy metal toxicity even though the results seems

to be

> in the normal to high normal range?

>

> Would it better to have them in low

> normal . . . I don't have a clue?

>

> immunoglobulin IGA 253 mg/dl range 40-375

>

> immunoglobulin IGG 1,160 mg/dl range 600-1,500

>

> immunoglobulin IGM 133 mg/dl range 30-190

>

> Thanks a bunch!

> Sue T

>

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

[Guest guest]

Hi, Sue.

It's good to hear that you're " back in the saddle again " some these

days!

It sounds as though your lymphocyte cell counts are pretty good, too.

Did they check your lymphocyte function, such as by provoking them

with conconavalin or pokeweed mitogen or bacterial polysaccharides?

In CFS, the T cells tend not to be able to respond normally when

provoked, and the NK cells tend to have low activity. The cell

counts may be normal, but the cells may still not be able to respond

as they should. The U. of Miami group found that both the killer T

cells and the natural killer cells are low in perforin in CFS, and

that may be contributing to their low activity. As I mentioned

before, I think that both glutathione depletion and folate

metabolism problems are involved in this, too. I don't know yet if

there is a connection between them and the low perforin, but there

may be.

I'll look forward to seeing your additional test results, and I'm

glad you are going to pursue the endocrine stuff.

Rich

> >

> > Hi Rich and All,

> >

> > My infectious disease doc ran some immunoglobulin testing.

> >

> > Can anyone give me an idea what this may mean to me in regards

to

> my

> > CFS, Lyme, and heavy metal toxicity even though the results

seems

> to be

> > in the normal to high normal range?

> >

> > Would it better to have them in low

> > normal . . . I don't have a clue?

> >

> > immunoglobulin IGA 253 mg/dl range 40-375

> >

> > immunoglobulin IGG 1,160 mg/dl range 600-1,500

> >

> > immunoglobulin IGM 133 mg/dl range 30-190

> >

> > Thanks a bunch!

> > Sue T

> >

>

>

>

>

>

>

>

> This list is intended for patients to share personal experiences

with each other, not to give medical advice. If you are interested

in any treatment discussed here, please consult your doctor.

>

>

>

>

[Guest guest]

HI Rich,

I will ask Kaiser to run the function tests next time.

Do you know how Moducare works? I understand it is suppose to help the the

Th1/Th2 response system?

Hope you are doing well.

I am in the middle of listening to you radio program and it is Excellent!

Sue T

rvankonynen <richvank@...> wrote:

Hi, Sue.

It's good to hear that you're " back in the saddle again " some these

days!

It sounds as though your lymphocyte cell counts are pretty good, too.

Did they check your lymphocyte function, such as by provoking them

with conconavalin or pokeweed mitogen or bacterial polysaccharides?

In CFS, the T cells tend not to be able to respond normally when

provoked, and the NK cells tend to have low activity. The cell

counts may be normal, but the cells may still not be able to respond

as they should. The U. of Miami group found that both the killer T

cells and the natural killer cells are low in perforin in CFS, and

that may be contributing to their low activity. As I mentioned

before, I think that both glutathione depletion and folate

metabolism problems are involved in this, too. I don't know yet if

there is a connection between them and the low perforin, but there

may be.

I'll look forward to seeing your additional test results, and I'm

glad you are going to pursue the endocrine stuff.

Rich

> >

> > Hi Rich and All,

> >

> > My infectious disease doc ran some immunoglobulin testing.

> >

> > Can anyone give me an idea what this may mean to me in regards

to

> my

> > CFS, Lyme, and heavy metal toxicity even though the results

seems

> to be

> > in the normal to high normal range?

> >

> > Would it better to have them in low

> > normal . . . I don't have a clue?

> >

> > immunoglobulin IGA 253 mg/dl range 40-375

> >

> > immunoglobulin IGG 1,160 mg/dl range 600-1,500

> >

> > immunoglobulin IGM 133 mg/dl range 30-190

> >

> > Thanks a bunch!

> > Sue T

> >

>

>

>

>

>

>

>

> This list is intended for patients to share personal experiences

with each other, not to give medical advice. If you are interested

in any treatment discussed here, please consult your doctor.

>

>

>

>