Re: Chlamydia--why them in CFS?

[Guest guest]

i like all these glutathione posts...especially how short the half

life is in the blood, my goodness...

when i was first getting it, i'd feel " happy " , or rather, my body

would feel " glad. " I don't notice that anymore....

I wonder if I should try more. I think I'm getting 1000 mg, once a

week, in a chaser. I think I'll try that nasal spray or sublingual.

Have to do more research on that.

I really didn't like the whey products...I wonder if the nasal spray

is actually effective.

>

> Hi, all.

>

> O.K., I've talked about why the Herpes family of viruses acts up in

> CFS (Epstein--Barr, HHV-6, cytomegalovirus, etc.), and why the

> mycoplasma get into the act, too, so now what about the other major

> pathogen, chlamydiae? Why does it become active in CFS?

>

> Well, if you've been reading my recent messages, you already know

> that the answer is always the same: glutathione depletion!

>

> But what are the specifics? How does glutathione impact

chlamydia?

> Well, I've just spent a few hours getting to know the chlamydia a

> little better, and I think I have a clue. I've learned that the

> chlamydia have kind of a unique life cycle. As you may know,

> chlamydia live and reproduce inside our cells. They exist in two

> forms, called the " elementary body " and the " reticulate body, " and

> they cycle between them. When a chlamyidiae is leaving a cell to

go

> and invade another one, it is in the form of the elementary body,

> which is smaller and is wrapped up tightly in a protein coat that

is

> heavily cross-linked by (you guessed it!) disulfide bonds! When it

> enters a new host cell, these bonds are broken and it expands into

> the larger reticulate body. In this form, it multiplies, and then

> the progeny convert back to the elementary body form for their

> departure from the new cell. It is known that in many cases the

> chlamydia just sit inside one of our cells and don't complete their

> life cycle and spread to other cells. It doesn't seem to be

> understood why this occurs, but I have a hunch that if glutathione

> is high enough in the cells, the disulfide bonds can't form, and

the

> chlamydiae can't convert to elementary bodies for the trip out.

> They get stuck, and they wait until the local glutathione gets

> depleted enough that the disulfide bonds will form, and then off

> they go!

>

> Old-timers on the list may recall that back in 1999 Dr. Cheney was

> giving talks in which he told about his testing of undenatured whey

> protein on his patients. He had only about 7 and 9 patients or so

> on the two products he tried at that time, but he found that

several

> had positive results. In the ones who were helped, he found that

> their active infections with Herpes family viruses, mycoplasma and

> chlamydia just vanished! Well, now this makes more sense to me.

> These three types of pathogens all need to have the glutathione

> depleted in order to do their thing, but by three different

> mechanisms! If the glutathione concentration is up where it should

> normally be, they are frozen in place and can't carry on active

> infections.

>

> The other interesting wrinkle here is that all these guys have

their

> own favorites among our cells to live in, and they don't all favor

> the same cell types. Furthermore, glutathione is

compartmentalized,

> so that different cell types have different normal glutathione

> concentrations. Some cell types will drop in glutathione before

> others, so some of these pathogens will probably become active

> before others as the CFS develops and progresses. The lower the

> overall glutathione status goes, the more these miserable creatures

> wake up and start causing trouble. Epstein--Barr likes to live in

B

> lymphocytes. HHV-6 seems to like several kinds of cells, including

> NK cells, T cells, cells in the nervous system, and endothelial

> cells (on the inner surface of blood vessels). That's probably why

> HHV-6 so commonly activates in CFS. It's like putting some money

on

> several numbers at the roulette wheel. The more places you have

> your chips sitting, the more likely the ball will drop into one of

> your slots.

>

> Well, I find all this very fascinating. If you're wondering what

> the message from all of this is to PWCs, it's that if you are

> plagued by any of these critters I've been talking about, getting

> your glutathione back up would be a very good way to put them in

> back into hibernation!

>

> Rich

[Guest guest]

Hi, Jill.

I think it would be helpful if you could get a measurement of your

blood glutathione level. Then you would have a better idea where it

is relative to normal, and would have a better basis for deciding

whether to try getting more.

Rich

>

> i like all these glutathione posts...especially how short the half

> life is in the blood, my goodness...

>

> when i was first getting it, i'd feel " happy " , or rather, my body

> would feel " glad. " I don't notice that anymore....

>

> I wonder if I should try more. I think I'm getting 1000 mg, once

a

> week, in a chaser. I think I'll try that nasal spray or

sublingual.

> Have to do more research on that.

>

> I really didn't like the whey products...I wonder if the nasal

spray

> is actually effective.

[Guest guest]

That's true, Rich, but the fact is, my alternative health costs are

already high and I'm not rich. That means, I am not you, no, just

kidding. Anyway, I avoid testing and try clinical measures as that

cuts down on costs and it seems like people have all kinds of things

to recommend to test, that can run into hundreds and thousands of $.

But if I try more and notice an improvement, well, that is an answer

in itself.

> >

> > i like all these glutathione posts...especially how short the

half

> > life is in the blood, my goodness...

> >

> > when i was first getting it, i'd feel " happy " , or rather, my body

> > would feel " glad. " I don't notice that anymore....

> >

> > I wonder if I should try more. I think I'm getting 1000 mg, once

> a

> > week, in a chaser. I think I'll try that nasal spray or

> sublingual.

> > Have to do more research on that.

> >

> > I really didn't like the whey products...I wonder if the nasal

> spray

> > is actually effective.

[Guest guest]

You want to cover staph next?

Doris

----- Original Message -----

O.K., I've talked about why the Herpes family of viruses acts up in

CFS (Epstein--Barr, HHV-6, cytomegalovirus, etc.), and why the

mycoplasma get into the act, too, so now what about the other major

pathogen, chlamydiae? Why does it become active in CFS?

[Guest guest]

Hi, Doris.

I'd love to, and hopefully will be able to, once this conference

paper is delivered. Time is running out on me right now, so I'm

going to have to stop having so much fun and do the work!

Rich

> You want to cover staph next?

> Doris

> ----- Original Message -----

> O.K., I've talked about why the Herpes family of viruses acts up

in

> CFS (Epstein--Barr, HHV-6, cytomegalovirus, etc.), and why the

> mycoplasma get into the act, too, so now what about the other

major

> pathogen, chlamydiae? Why does it become active in CFS?

>

>