Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 Here is a link that lists many of sx from all adrenal adenomas http://www.wrongdiagnosis.com/a/adrenal_adenoma_familial/symptoms.htm > > > > > > Okay, so I got my test results, > > > My aldo was <1.6 and my Renin was 2.0 > > > Does this mean I don't have PA????? > > > Bridget > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 So from that article: " A strong predictor for PA is a PRA level undetectable low, in a patient taking an ACE inhibitor " So does that mean I could still have it, being my raio is .8? Bridget > > > > Okay, so I got my test results, > > My aldo was <1.6 and my Renin was 2.0 > > Does this mean I don't have PA????? > > Bridget > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 If your Aldo is 16 and not 1.6 then you could possibly have PA. I am sure Dr Grim will give you his thoughts on this. > > > > > > Okay, so I got my test results, > > > My aldo was <1.6 and my Renin was 2.0 > > > Does this mean I don't have PA????? > > > Bridget > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 It was 1.6, which is low for upright position. I am so confused about all of this! The normal low for upright is 4 Bridget > > > > > > > > Okay, so I got my test results, > > > > My aldo was <1.6 and my Renin was 2.0 > > > > Does this mean I don't have PA????? > > > > Bridget > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 It is possible that someone wrote it down wrong > > > > > > > > > > Okay, so I got my test results, > > > > > My aldo was <1.6 and my Renin was 2.0 > > > > > Does this mean I don't have PA????? > > > > > Bridget > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 Hi Bridget:ARR is Aldosterone to Renin Ratio. Meaning divide aldosterone number to your renin. the higher the number from this divistion the most likely you may have PA. In most of PA patients Aldosterone is rather on the high side and renin is less than 1. In your case it appears to be the oposite. However, keep in mind that you are on medication that can and cause your renin to be high. So if you were on Toprol and other medication it is possible that your renin may have not measured properly. Also, did your doctor instruct you to take salt(salt loading) for at least a couple of days before doing the blood test? All of this can alter the results. Dr. Grim will give you more insights as the medication you were on during the tests. Hang in there.FarahOn Thu, Oct 22, 2009 at 10:28 AM, bridget <blueyes7648@...> wrote: Â I am still going to see an endo, I have been thinking cushing's as well, addison's causes low bp. do you know how they figure the ARR value? Bridget > > > > Okay, so I got my test results, > > My aldo was <1.6 and my Renin was 2.0 > > Does this mean I don't have PA????? > > Bridget > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 There is something wrong with those results. I seriously doubt aldo is <1.6 Val From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of bridget Okay, so I got my test results, My aldo was <1.6 and my Renin was 2.0 Does this mean I don't have PA????? Bridget Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 Val, maybe someone in the lab recorded it wrong or something, but I copied and pasted this from my online lab report. Bridget Component Results ALDOSTERONE, SERUM: <1.6 Unit: ng/dL (Note) REFERENCE INTERVALS: Aldosterone, Serum Reference intervals for age 15 and older: Upright ......... 4.0 - 31.0 ng/dL Supine .......... 16.0 ng/dL or less Unspecified ..... 31.0 ng/dL or less Normal serum levels of aldosterone are dependent on the sodium intake and whether the patient is upright or supine. High sodium intake will tend to suppress serum aldosterone, whereas low sodium intake will elevate serum aldosterone. The reference intervals for serum aldosterone are based on normal sodium intake. Performed by ARUP Laboratories, 500 Chipeta Way, SLC,UT 84108 800-522-2787 www.aruplab.com, Sherrie L. Perkins, MD, Lab. Director > > There is something wrong with those results. I seriously doubt aldo is <1.6 > > Val > > From: hyperaldosteronism > [mailto:hyperaldosteronism ] On Behalf Of bridget > > > Okay, so I got my test results, > My aldo was <1.6 and my Renin was 2.0 > Does this mean I don't have PA????? > Bridget > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2009 Report Share Posted October 22, 2009 Farah, thank you for the info. No, my doc didn't tell me to do anything at all, he was only doing the test because I suggested it and really doesn't know much about conn's. Bridget > > > > > > > > Okay, so I got my test results, > > > > My aldo was <1.6 and my Renin was 2.0 > > > > Does this mean I don't have PA????? > > > > Bridget > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 Very interesting. You likely have another problem that is causing a VERY low aldo and a low renin. (Assuming this is a true statement regarding the normal values for that lab). Causes include eating licorice or having one of 2 other rare problems: AME or Liddle's Syndrome.Read my article about licorice , AMI and Liddle's and talk to your Dr. I need to review Bridgit's story. Is it in our files? May your pressure be low!Clarence E. Grim, BS, MS, MDSpecializing in Primary Aldosteronism the most common cause of "Difficult/Drug Resistant High Blood Pressure". Other research interests focus on the interactions of recent evolutionary forces on the body's ability to handle salt and the effect of dietary salt on blood pressure in populations today.Listed in Best Doctors of America 2009. On Oct 22, 2009, at 11:00 AM, bridget wrote: Okay, so I got my test results, My aldo was <1.6 and my Renin was 2.0 Does this mean I don't have PA????? Bridget Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 Where do you live I may know someone in the area. May your pressure be low!Clarence E. Grim, BS, MS, MDSpecializing in Primary Aldosteronism the most common cause of "Difficult/Drug Resistant High Blood Pressure". Other research interests focus on the interactions of recent evolutionary forces on the body's ability to handle salt and the effect of dietary salt on blood pressure in populations today.Listed in Best Doctors of America 2009. On Oct 22, 2009, at 12:22 PM, Lori wrote: You were on medications and I have no idea if it can affect the lab values. Can't 's or Cushings cause low aldo and renin ? And I know Cushings causes uncontrolled hypertension.I think 's is the opposite. I still think you shoud see an endo.I know how frustrating it is to go thru test after test and have no answers but it is out there and you will find it. An endo knows alot more about this and I hope u can find a really good one who will evaluate you well. Please keep us posted,Lori From: bridget <blueyes7648 >Subject: Re: test resultshyperaldosteronism Date: Thursday, October 22, 2009, 11:08 AM I was on Lisiniprol, but off for a week before the blood work, and on 150 mg of toprol during the test.>> Okay, so I got my test results, > My aldo was <1.6 and my Renin was 2.0> Does this mean I don't have PA?????> Bridget> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 's has low aldo and high renin. You do not have that.Cushings can often be suspected by looking at the Driver's lic picture. 'Google Cushing's Images and see if you look like that. Cushing's is one of the Dxs that can be made when the patient walks in the room. There are several others that cause high blood pressure that can be suspected when the patient walks in the room. May your pressure be low!Clarence E. Grim, BS, MS, MDSpecializing in Primary Aldosteronism the most common cause of "Difficult/Drug Resistant High Blood Pressure". Other research interests focus on the interactions of recent evolutionary forces on the body's ability to handle salt and the effect of dietary salt on blood pressure in populations today.Listed in Best Doctors of America 2009. On Oct 22, 2009, at 12:28 PM, bridget wrote: I am still going to see an endo, I have been thinking cushing's as well, addison's causes low bp. do you know how they figure the ARR value? Bridget > > > > Okay, so I got my test results, > > My aldo was <1.6 and my Renin was 2.0 > > Does this mean I don't have PA????? > > Bridget > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 Again you have something very interesting going on. Where do You live I may know an expert in the area. May your pressure be low!Clarence E. Grim, BS, MS, MDSpecializing in Primary Aldosteronism the most common cause of "Difficult/Drug Resistant High Blood Pressure". Other research interests focus on the interactions of recent evolutionary forces on the body's ability to handle salt and the effect of dietary salt on blood pressure in populations today.Listed in Best Doctors of America 2009. On Oct 22, 2009, at 11:18 PM, bridget wrote: Val, maybe someone in the lab recorded it wrong or something, but I copied and pasted this from my online lab report. Bridget Component Results ALDOSTERONE, SERUM: <1.6 Unit: ng/dL (Note) REFERENCE INTERVALS: Aldosterone, Serum Reference intervals for age 15 and older: Upright ......... 4.0 - 31.0 ng/dL Supine .......... 16.0 ng/dL or less Unspecified ..... 31.0 ng/dL or less Normal serum levels of aldosterone are dependent on the sodium intake and whether the patient is upright or supine. High sodium intake will tend to suppress serum aldosterone, whereas low sodium intake will elevate serum aldosterone. The reference intervals for serum aldosterone are based on normal sodium intake. Performed by ARUP Laboratories, 500 Chipeta Way, SLC,UT 84108 800-522-2787 www.aruplab.com, Sherrie L. Perkins, MD, Lab. Director > > There is something wrong with those results. I seriously doubt aldo is <1.6 > > Val > > From: hyperaldosteronism > [mailto:hyperaldosteronism ] On Behalf Of bridget > > > Okay, so I got my test results, > My aldo was <1.6 and my Renin was 2.0 > Does this mean I don't have PA????? > Bridget > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 ly, there is not much distance between northern Minnesota and Milawaukee. Brigid should just go see Dr. Grim. Bindner Web Directory (links to my sites and blogs): http://www.geocities.com/mikeybdc/index.html http://mikeybdc.blogspot.com >> There is something wrong with those results. I seriously doubt aldo is <1.6> > Val> > From: hyperaldosteronism> [mailto:hyperaldosteronism] On Behalf Of bridget> > > Okay, so I got my test results, > My aldo was <1.6 and my Renin was 2.0> Does this mean I don't have PA?????> Bridget> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 I would go to the Mayo clininc. I am not seeing patients now as have retired. But having fun doing this and when I retire to Tahoe will likely set up clinic in S Lake. May your pressure be low!Clarence E. Grim, BS, MS, MDSpecializing in Primary Aldosteronism the most common cause of "Difficult/Drug Resistant High Blood Pressure". Other research interests focus on the interactions of recent evolutionary forces on the body's ability to handle salt and the effect of dietary salt on blood pressure in populations today.Listed in Best Doctors of America 2009. On Oct 23, 2009, at 5:10 AM, Bindner wrote: ly, there is not much distance between northern Minnesota and Milawaukee. Brigid should just go see Dr. Grim. Bindner Web Directory (links to my sites and blogs): http://www.geocities.com/mikeybdc/index.html http://mikeybdc.blogspot.com Val, maybe someone in the lab recorded it wrong or something, but I copied and pasted this from my online lab report.BridgetComponent Results ALDOSTERONE, SERUM: <1.6Unit: ng/dL(Note)REFERENCE INTERVALS: Aldosterone, SerumReference intervals for age 15 and older:Upright ......... 4.0 - 31.0 ng/dLSupine .......... 16.0 ng/dL or lessUnspecified ..... 31.0 ng/dL or lessNormal serum levels of aldosterone are dependent on thesodium intake and whether the patient is upright orsupine. High sodium intake will tend to suppress serumaldosterone, whereas low sodium intake will elevate serumaldosterone. The reference intervals for serum aldosteroneare based on normal sodium intake.Performed by ARUP Laboratories,500 Chipeta Way, SLC,UT 84108 800-522-2787www.aruplab. com, Sherrie L. Perkins, MD, Lab. Director>> There is something wrong with those results. I seriously doubt aldo is <1.6> > Val> > From: hyperaldosteronism> [mailto:hyperaldosteronism] On Behalf Of bridget> > > Okay, so I got my test results, > My aldo was <1.6 and my Renin was 2.0> Does this mean I don't have PA?????> Bridget> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 Some labs say that blood can't be refrigerated but has to be frozen or room temp. > > > > > > There is something wrong with those results. I seriously doubt > > aldo is <1.6 > > > > > > Val > > > > > > From: hyperaldosteronism > > > [mailto:hyperaldosteronism ] On Behalf Of bridget > > > > > > > > > Okay, so I got my test results, > > > My aldo was <1.6 and my Renin was 2.0 > > > Does this mean I don't have PA????? > > > Bridget > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 It is the ratio not the ranges that matters in PA. Most use a ratio 20 or higher to show PA. 20 is used becaues 80% of the time you have PA. Can still have PA at lower ratio just less chance of it. At some ratio it would be a 50% chance that you have PA. I think that just looking at the ratio that is 20 or above does a disservice to 75% of those that may have PA. > > My Aldo ranges upright were <= 28, <=21. No lower limit. > Leads me to believe there's a lot of " leeway " in the measurement. > Regards > > RE: test results > > > > There is something wrong with those results. I seriously doubt aldo is <1.6 > > > > Val > > > > From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of bridget > > > > Okay, so I got my test results, > My aldo was <1.6 and my Renin was 2.0 > Does this mean I don't have PA????? > Bridget > > > > > > > __________ NOD32 4389 (20090902) Information __________ > > This message was checked by NOD32 antivirus system. > http://www.eset.com > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 It is the ratio not the ranges that matters in PA. Most use a ratio 20 or higher to show PA. 20 is used becaues 80% of the time you have PA. Can still have PA at lower ratio just less chance of it. At some ratio it would be a 50% chance that you have PA. I think that just looking at the ratio that is 20 or above does a disservice to 75% of those that may have PA. > > My Aldo ranges upright were <= 28, <=21. No lower limit. > Leads me to believe there's a lot of " leeway " in the measurement. > Regards > > RE: test results > > > > There is something wrong with those results. I seriously doubt aldo is <1.6 > > > > Val > > > > From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of bridget > > > > Okay, so I got my test results, > My aldo was <1.6 and my Renin was 2.0 > Does this mean I don't have PA????? > Bridget > > > > > > > __________ NOD32 4389 (20090902) Information __________ > > This message was checked by NOD32 antivirus system. > http://www.eset.com > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 My Aldo ranges upright were <= 28, <=21. No lower limit. Leads me to believe there's a lot of "leeway" in the measurement. Regards RE: test results There is something wrong with those results. I seriously doubt aldo is <1.6 Val From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of bridget Okay, so I got my test results, My aldo was <1.6 and my Renin was 2.0Does this mean I don't have PA?????Bridget __________ NOD32 4389 (20090902) Information __________This message was checked by NOD32 antivirus system.http://www.eset.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 My Aldo ranges upright were <= 28, <=21. No lower limit. Leads me to believe there's a lot of "leeway" in the measurement. Regards RE: test results There is something wrong with those results. I seriously doubt aldo is <1.6 Val From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of bridget Okay, so I got my test results, My aldo was <1.6 and my Renin was 2.0Does this mean I don't have PA?????Bridget __________ NOD32 4389 (20090902) Information __________This message was checked by NOD32 antivirus system.http://www.eset.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 Have you thought about doing video conferences. > >> > > >> > There is something wrong with those results. I seriously doubt > >> aldo is <1.6 > >> > > >> > Val > >> > > >> > From: hyperaldosteronism > >> > [mailto:hyperaldosteronism] On Behalf Of bridget > >> > > >> > > >> > Okay, so I got my test results, > >> > My aldo was <1.6 and my Renin was 2.0 > >> > Does this mean I don't have PA????? > >> > Bridget > >> > > >> > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 not sure what that is, with the doctors? > > >> > > > >> > There is something wrong with those results. I seriously doubt > > >> aldo is <1.6 > > >> > > > >> > Val > > >> > > > >> > From: hyperaldosteronism > > >> > [mailto:hyperaldosteronism] On Behalf Of bridget > > >> > > > >> > > > >> > Okay, so I got my test results, > > >> > My aldo was <1.6 and my Renin was 2.0 > > >> > Does this mean I don't have PA????? > > >> > Bridget > > >> > > > >> > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 Was refering to Dr Grim doing them. Video conferences are done over the Internet I bit like useing a web cam. The idea being He could teach hundreds of doctors at one time. He can do this from his home if he has the setup. > > > >> > > > > >> > There is something wrong with those results. I seriously doubt > > > >> aldo is <1.6 > > > >> > > > > >> > Val > > > >> > > > > >> > From: hyperaldosteronism > > > >> > [mailto:hyperaldosteronism] On Behalf Of bridget > > > >> > > > > >> > > > > >> > Okay, so I got my test results, > > > >> > My aldo was <1.6 and my Renin was 2.0 > > > >> > Does this mean I don't have PA????? > > > >> > Bridget > > > >> > > > > >> > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 The ratio is only a screening test. If it shows you could have PA then should have more tests done. > > > > My Aldo ranges upright were <= 28, <=21. No lower limit. > > Leads me to believe there's a lot of " leeway " in the measurement. > > Regards > > > > RE: test results > > > > > > > > There is something wrong with those results. I seriously doubt aldo is <1.6 > > > > > > > > > . > > > > > __________ NOD32 4389 (20090902) Information __________ > > This message was checked by NOD32 antivirus system. > http://www.eset.com > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2009 Report Share Posted October 23, 2009 From Mayo lab site A high ratio of SA (in ng/dL) to PRA (in ng/mL/hour) is a positive screening test result, a finding that warrants further testing. An SA/PRA ratio >20 and SA >15 ng/dL indicates probable primary aldosteronism. Confirmatory testing—aldosterone suppression testing An elevated SA/PRA ratio is not diagnostic by itself, and primary aldosteronism must be confirmed by demonstrating inappropriate aldosterone secretion. The list of drugs and hormones capable of affecting the renin-angiotensin-aldosterone axis is extensive; and frequently in patients with severe hypertension, a " medication-contaminated " evaluation is unavoidable. Calcium channel blockers, & #945;1 & #8722;adrenergic receptor blockers, and ß-adrenergic receptor blockers do not affect the diagnostic accuracy in most cases. It is impossible to interpret data obtained from patients receiving treatment with spironolactone. Therefore, spironolactone treatment should not be initiated until the evaluation is completed and the final decisions about treatment are made. If primary aldosteronism is suspected in a patient receiving treatment with spironolactone, the treatment should be discontinued for at least 6 weeks. I would as long as you are doing good wouldn't be overly concerned. I would just keep a watch on things and if you start seening things in your self that you are seening in others on here. Then you might want to do other tests. At this time I can't say for sure if I have PA but based on what I see here I belive I do. A lot of little things have been going on with me that I now think have led up to a big thing. I belive what pushed it over edge was doing a lot labor it the hot humid weather. Loseing more K then I was replacing. I think at this point my system was no longer able to overcome the aldo. > > > > > > My Aldo ranges upright were <= 28, <=21. No lower limit. > > > Leads me to believe there's a lot of " leeway " in the measurement. > > > Regards > > > > > > RE: test results > > > > > > > > > > > > There is something wrong with those results. I seriously doubt aldo is <1.6 > > > > > > > > > > > > > > . > > > > > > > > > > __________ NOD32 4389 (20090902) Information __________ > > > > This message was checked by NOD32 antivirus system. > > http://www.eset.com > > > > > > > > > __________ NOD32 4389 (20090902) Information __________ > > This message was checked by NOD32 antivirus system. > http://www.eset.com > Quote Link to comment Share on other sites More sharing options...
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