Guest guest Posted December 22, 2006 Report Posted December 22, 2006 A big > challenge likely is that the medications that are now considered front-line > treatment haven't been shown yet to extend survival (or is that data now > coming in?). >****************************************** I would say that there is clear evidence to show that Gleevec is extending survival for CMLer's. Just look at the 5 year data for Gleevec users as compared to people who have had a BMT. According to http://www.marrow.org/PHYSICIAN/URD_Search_and_Tx/Comparing_URD_Sibling_ Donor_Tx/index.html The five year survival rate for people who had a BMT for CML is 53%. Now compare that with the recent 5 year statistics for Gleevec users (the IRIS trial)and there's really no comparison at all. 5 year survival rates for Gleevec users is over 90%. Looks pretty clear to me Tracey Quote
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