Re: Interesting timing of article post CHF story

July 27, 2006

At 03:07 PM 7/27/06 -0400, you wrote:

> It is not new but was moderately successful with a

>small subset of patients in combination with IFN and IFN + Ara-C. Both

>Jerry Mayfield and Cogan tried it but were not successful with

>these combos. It is now being investigated again and may have some

>effect on T315i.

Hi ,

Yes, this is hardly a new drug. It was in 1999 that I tried triple therapy

(inf, ara-c and HHT). MDACC had quite a few people in trial for a long

period of time. I think Jerry was on this cocktail for about a year with no

benefit. I did not tolerate and was off in 3 months. I don't know anyone

who did not eventually relapse....then move onto Gleevec. There have been

trial combining Gleevec and HHT....I think in the Netherlands did

this in the UK.....it was not tolerable and did not benefit her (that is

what I am remembering).

From the article you posted:

" Our drug is the only one in late stage trials that has a different

mechanism so this expands the potential market, " he said.

This comment looks like the main reason for them writing the article that

they did......trying to grab a share of the market, or impress investors

that they will. We don't like big money factoring into our health

care.....but the truth is that this is what is driving the drug companies!!

We can be so glad that the L & L Society is funding so much research, such as

that done by Dr. Druker, Dr. Sawyers and others.

C.

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