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Hi, I'm Fran from Alaska who used to post on the old CML group. I lost

track of you guys until a thanks to a recent email from Zavie, I found

this group. After 5 years in complete cytogenetic remission, my

last PCR detected leukemia cells again (still a low number). My doctor

recommended increasing my gleevec dose to 600mg. (from the 300mg. I've

been on for 5 years). I'm doing ok on the 600mg which is surprising

as in the past my blood counts have not been able to maintain on

higher doses. Just an update and open to any advice from other long

time gleevec users whose results have detected BCR-ABL cells after a

long CCR. I'll have another PCR in May to see if the BCR-ABL cells are

the same, increasing or gone. I'm hoping for gone!

Fran

dx 5/99

Peg Interferon and Ara C 1/2000-5/2001-CCR 10/2000

gleevec 300mg 7/01-3/06 then increasing to 600mg 4/06

Currently PCR by Fred Hutch measures--148 BCR-ABL cells detected

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