Re: New to group --- question regarding hospitalization & symptomsou

[Guest guest]

Thank you for your input. I know that Dr. Giles is one of the doctors that

participates in many of the new studies. I see his name on a number of

abstracts along with Dr. Talpaz who left MD last year.

With warm regards,

Matt

ville, FL

DX January of 2005

Gleevec Since May 2005

Father of 3

mtmaynor@...

In a message dated 11/13/2006 10:12:10 A.M. Eastern Standard Time,

no_reply writes:

Hi

Just my 2 cents-I was at a meeting at Princess Margaret Hospital in

Toronto in September where Dr. Giles from MD was speaking.

In HIS opinion 800 mg is the optimal dosage for newly diagnosed

patients in chronic phase. Your doctor and you will decide what is

the best dosage for you. Each case is different and personal.

[Guest guest]

---

Hi

Just my 2 cents-I was at a meeting at Princess Margaret Hospital in

Toronto in September where Dr. Giles from MD was speaking.

In HIS opinion 800 mg is the optimal dosage for newly diagnosed

patients in chronic phase. Your doctor and you will decide what is

the best dosage for you. Each case is different and personal.

In , " Tracey " <traceyincanada@...> wrote:

>

> Hi Matt,

>

> Can you tell us where on the Novartis site you read that 800mg is

> the standard dose for chronic phase patients?

>

> All the Novartis prescribing information that I've read, clearly

> states that 400mg is the standard dose for chronic phase patients.

> http://www.pharma.us.novartis.com/product/pi/pdf/gleevec_tabs.pdf

> The dosing is on page 26.

>

> My personal feeling is that if I can get a good response from

400mg,

> then I can't see any reason to tax my body with a dose of 800mg,

> especially knowing that I'm going to be on this drug for the rest

of

> my life.

>

> Take care,

> Tracey

>

>

>

> > I was told by MD ,

> > Shands Cancer Center and the LLS that 400 mg was not an

> appropriate initial dosage

> > and that 800 mg was the proper dosage for the newly diagnosed if

> they can

> > tolerate it. In fact, when I was first prescribed 400 mg, the

> LLS sent the

> > local representative from Novartis to the oncologist that

> prescribed me that

> > amount to tell him that this is not the optimal dose for newly

> diagnosed CML

> > patients.

> >

> > But then again, that is what they are telling me. What do I

> really know,

> > other than what I read on the Novartis site and what MD

> says is the

> > proper protocol.

> >

> > But yes, I realize that a number of people are on 400 mg or even

> less. And

> > yes, I realize that opinions differ as to what dosage is

> appropriate. I

> > think the bottom line is that if you are responding to your

> dosage at the level

> > you are at, then it is the appropriate dose for you.

> >

> > With warm regards,

> > Matt

> > ville, FL

> > DX January of 2005

> > Gleevec Since May 2005

> > Father of 3

> > mtmaynor@

> > In a message dated 11/11/2006 9:27:26 P.M. Eastern Standard

Time,

> > traceyincanada@ writes:

> >

> > Hi Matt,

> >

> > Actually 400mg is the standard dose for newly diagnosed patients

> in

> > chronic phase. It's not considered to be a low dose and there

are

> many

> > of us who have been on 400mg for our entire CML career... some

> are even

> > PCRU. I've been on 400mg since Feb 2002 and I've achived a 3.5

log

> > reduction.

> >

> > Take care,

> > Tracey

> >

> >

> >

> >

> >

> >

> >

> >

> >