Hi all,

[Guest guest]

reading the latests posts I can't dismiss the eiry feeling that lately

there is a mind struggle going on between some members in particular.

Could that perhaps be kept between the parties concerned ?

And if not then please show your credentials (private mails) so we all

can enjoy the razzamatazz!

This used to be a friendly forum with friendly exchange of knowledge

gathered.

love and peace to all of you!

Ursula

[Guest guest]

My workplace (Virginia Mason Hospital in Seattle) requires H1N1 and regular flu

shot for " fitness for duty " requirements and so I will be having both, though as

yet we haven't had enough of the H1N1 to go around, and regular flu shots were

given while I was out sick, so I have to get both.

>

> I am now having Philadelphia chromosome show up again in my blood work so I am

having another bone marrow biopsy in early November, and I am guessing I will be

switched to a different medication. I'm on Gleevec 600 mg per day, and it has

never worked all that well for me--I seem to be rather resistant, or my leukemia

is rather resistant, I should say. Can anybody tell me what the usual next drug

is if Gleevec is not working well?

_________________

Hi Vicki,

I am sorry about little Roscoe. I am sure he had a great life with you.

Because you had a case of H1N1, you now have immunity and would not need a shot,

but your work may still require it.

If 600mg of Gleevec is not working, then you would need a new drug (rather than

increase the dose). Before deciding on a drug, they need to do a mutations test

to see if you have any binding point mutations that interfere with the drug

working and that helps determine what drug to use next.

Because you are so close to Portland and OHSU, I would go for a consult there

and let them, with all their expertise, make the decision and do what ever

special testing that you need. When the primary drug (Gleevec) is not working

for you, this is when you need to see a CML specialist. You don't want to waste

time with a drug that is not working well for you.

Best wishes,

C.