assessing risks and benefits in CT

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hello,Risk is a

multidimensional concept involving both the probability and magnitude of harms to research

participants. The proper ethical analysis of risk

requires that both the magnitude of the

harm and its probability of occurring be considered.eg. A risk of death of one

in one million has to be treated differently than a risk of death of one in

ten.

Read carefully the

following two case studies:

Study A:

Placebo controlled

trial of a drug for people with acutely symptomatic schizophrenia.

The study involves

schizophrenic patients who are newly hospitalized with acute symptoms of their

disease. Despite the existence

of effective treatment for such symptoms, patients are randomized to a new antipsychotic drug, a

standard drug, or placebo. Patients are treated in hospital for four weeks, and

a variety of psychometric scales are measured..

Study B:

Questionnaire examining adolescent sexual practices.

The study involves the

administration of a pencil and paper questionnaire to 400 Minneapolis high school students during

regularly scheduled health classes. The survey seeks to document attitudes and

behaviors related to HIV prevention. Accordingly, adolescent participants are

asked whether they are sexually active, what types of sexual activity they have

experienced (e.g., oral, vaginal, or anal intercourse), and the gender(s) of

their partners. A variety of risks are presented by this study to participants

..

Before we proceed

further, to remind you of the classification dealt with in the earlier post, risks

are classified into four categories:

physical, psychological, social,and economic.

Physical risks.

The research subject

may suffer bodily harm - minor or serious, temporary or permanent, immediate or

delayed - as a result of his or her participation in the study.

Psychological risks.

Study participation

may impact upon the research subject's perception of self and cause emotional

suffering, e.g., anxiety or shame, or may induce aberrations in thought or

behavior.

Social risks.

Research findings, or

even study participation itself, may expose subjects to the possibility of

insurance or employment discrimination or other forms of social stigmatization.

Economic risks.

Research

subjects may directly or indirectly costs related to research participation

Exercise

1

Using

this classification can we now assign the type of risk/s involved in the above two case studies? There could be several risks in one study itself. The

more you can think of, the closer you would be to the answer.kunda

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