Guest guest Posted October 31, 2004 Report Share Posted October 31, 2004 Ann's comment about Campath posted above a paper dealing with Fludarabine and alkylators seems somewhat out of place. Was that a mistake or am I not getting the message here? I think a lot of new therapies have come down the pipe since Fludara and alkylators so is there a reason for the focus on Campath only? Fred Hummel, 78, Arcata, CA; CLL/SLL dx 1.98; Fludara 2000; Rituxan, Fludara, Novantrone, & Decadron, April-August 2002; Rituxan X 4, Aug-Sep 2004. > Campath is looking better and better. > Ann > > Leuk Lymphoma. 2004 Nov;45(11):2239-45. Related Articles, Links > > Fludarabine in Comparison to Alkylator-based Regimen as Induction > Therapy for Chronic Lymphocytic Leukemia: A Systematic Review and > Meta-analysis. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 31, 2004 Report Share Posted October 31, 2004 Fred, I agree, the problems with Fludurabine are well established, but they are in no way less than the problems associated with Campath, if anything very similar, but probably not quite as bad as Campath. So, your right the conclusion that it means that Campath is the obvious answer to Fludurabines failures, is by no means a sensible conclusion. Perhaps Ann is just an interested patient trying to be involved like us all , who made a conclusion on her own. Perhaps something she is answering for herself at the moment. But her presentation or off the cuff assessment lacks a certain necessary set-up to properly present her idea so that we can follow along or begin to agree. I also think Campath in certain patients has been very successful, wildly so, but on the other side of the coin, for every success there are 10 miserable failures and patients that end up with horribly compromised immune systems and very sick and infiltrated marrow after trying Campath. It's truly a very dangerous monoclonal antibody......especially as compared to Rituxan. My situation is even more evidence against such treatments. I took everything mild, " LRCP " (leukapheresis, Rituxan, Chlorambucil/Prednisone) and I have a remission now for 2 years. I have damaged nothing meanwhile. My CBC counts are normal across the board with the lone exception of Platelets, but they remain in a very safe place always somewhere between 85 - 175. Everything else is exceptional. I live a normal life. I have no doubt that some day I will need to take either Fludurabine or Campath or some of the other dangerous protocols. But, until then I have thus far extended my life by 5 yrs thus far without having to take any of the dangerous stuff. If I had taken Fludurabine or Campath 5 yrs ago as I was strongly advised to do by the honorable Kipps and Marti and Coutre and all the doctors I saw, where would I be today? Food for thought. Regards, Kurt Re: Fludarabine Ann's comment about Campath posted above a paper dealing with Fludarabine and alkylators seems somewhat out of place. Was that a mistake or am I not getting the message here? I think a lot of new therapies have come down the pipe since Fludara and alkylators so is there a reason for the focus on Campath only? Fred Hummel, 78, Arcata, CA; CLL/SLL dx 1.98; Fludara 2000; Rituxan, Fludara, Novantrone, & Decadron, April-August 2002; Rituxan X 4, Aug-Sep 2004. > Campath is looking better and better. > Ann > > Leuk Lymphoma. 2004 Nov;45(11):2239-45. Related Articles, Links > > Fludarabine in Comparison to Alkylator-based Regimen as Induction > Therapy for Chronic Lymphocytic Leukemia: A Systematic Review and > Meta-analysis. > Let's keep the list UNCLUTTERED!!! To do ANY HOUSEKEEPING business such as changing the way you get mail, please go to mygoups or mail me at scott_fs@.... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 20, 2011 Report Share Posted March 20, 2011 I had FR ten years ago. Who can complain? And, as Pat says, it still is the " gold standard " But, in my own case, now fighting a second cancer, there is a question of whether the F may not be responsible for some of my current CBC numbers. Perhaps the doctors will comment. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 21, 2011 Report Share Posted March 21, 2011 , If you do not mind me asking, is second cancer a solid cancer? My husband too is fighting a second cancer. carla Quote Link to comment Share on other sites More sharing options...
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