Guest guest Posted August 23, 2004 Report Share Posted August 23, 2004 It took forever to get a response, but a while back I wrote a question about Heterochromia on a genetics website. " Question: I have Heterochromia iridis (different colored eyes, where one eye is of two colors), and I was wondering if there are statistics on how many other people have this trait? My particular case is independent of disease or disorder, but I was curious. Answer: We were unable to find a specific number for the frequency of heterochromia of the iris in the general population. Asymmetry in the pigmentation of the irides probably occurs as an isolated phenomenon inherited as a dominant trait. This means a parent with heterochromia of the iris has a 50/50 chance to pass the trait to their offspring. " http://server2k.genetics.emory.edu/ask/user/view_response.pl? resp=142 & temp=3 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 24, 2004 Report Share Posted August 24, 2004 That's really cool that they answered you. His answer doesn't seem to hold up in my case though. My grandmother has heterochromia (no related diseases). None of her five children (including my mom) has heterochromia, but somehow I do. Both of my (American) parents have English ancestry, so maybe there is a recessive gene in there somewhere that caused this? Or maybe my mom has extremely slight heterochromia that I've never noticed? I will have to look again next time I see her. Thanks for posting this, very thought provoking. > It took forever to get a response, but a while back I wrote a > question about Heterochromia on a genetics website. > > > " Question: > I have Heterochromia iridis (different colored eyes, where one eye > is of two colors), and I was wondering if there are statistics on > how many other people have this trait? My particular case is > independent of disease or disorder, but I was curious. > > Answer: > We were unable to find a specific number for the frequency of > heterochromia of the iris in the general population. Asymmetry in > the pigmentation of the irides probably occurs as an isolated > phenomenon inherited as a dominant trait. This means a parent with > heterochromia of the iris has a 50/50 chance to pass the trait to > their offspring. " > > http://server2k.genetics.emory.edu/ask/user/view_response.pl? > resp=142 & temp=3 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 24, 2004 Report Share Posted August 24, 2004 -- Hmm, I guess this is where the multiple genes controlling eye color thing would come in and make it more complicated that it first appears. I wrote back to them and told them about this group, since there seems to be alot of unknowns in the Heterochromia world. I figured if they were interested in researching, there is a large group of potential subjects right here, some of which might be interested in participating in research... I'll let you know what they say... ______________________________________ K. US2002066259 Acting Chapter Coordinator Phoenix House CA-003-C Domain of Los Angeles CA-053-D Los Angeles, California Geek insult: " Get back to me when you can pass a Turing test. " Quoting littlel77 <lcountee@...>: > That's really cool that they answered you. His answer doesn't seem to > hold up in my case though. My grandmother has heterochromia (no > related diseases). None of her five children (including my mom) has > heterochromia, but somehow I do. Both of my (American) parents have > English ancestry, so maybe there is a recessive gene in there > somewhere that caused this? Or maybe my mom has extremely slight > heterochromia that I've never noticed? I will have to look again next > time I see her. > > Thanks for posting this, very thought provoking. > > > > > > It took forever to get a response, but a while back I wrote a > > question about Heterochromia on a genetics website. > > > > > > " Question: > > I have Heterochromia iridis (different colored eyes, where one eye > > is of two colors), and I was wondering if there are statistics on > > how many other people have this trait? My particular case is > > independent of disease or disorder, but I was curious. > > > > Answer: > > We were unable to find a specific number for the frequency of > > heterochromia of the iris in the general population. Asymmetry in > > the pigmentation of the irides probably occurs as an isolated > > phenomenon inherited as a dominant trait. This means a parent with > > heterochromia of the iris has a 50/50 chance to pass the trait to > > their offspring. " > > > > http://server2k.genetics.emory.edu/ask/user/view_response.pl? > > resp=142 & temp=3 > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2004 Report Share Posted October 16, 2004 Hi - It's still likely to be a dominant gene in your case.. It has a very variable expression, so it could be anything from really obvious to not visually observable. Since you have it, it could be said your mother inherited the gene but did not 'exhibit' the trait herself. That wouldn't have stopped her from passing it on genetically, nor would have it stopped any of her offspring who inherited the gene from expressing it visually. To give an example, it's very possible(expected, actually) for identical twins with the gene to have different eyes from each other. One twin could have heterochromia irides and the other not, or both have it except the colors are reversed.. or not.. if they have heterochromia iridis, they will not be the same in both twins. The possiblites are endless just in this twin case. It has to do with the migration of the pigment cells in the embryo. If it were to be a recessive trait, it would be an amazing concidence that both of your maternal great-grandparents happened to have it and showed up in your grandmother and then for your mother to marry someone who happens to be a recessive carrier. Not completely impossible but " pretty strongly unlikely " . Basically if you or anybody on the maternal side produces a baby with heterochromia(assuming the partner does not have heterochromia) it would pretty much seal it as being a dominant, but with an extremely variable expression. > > It took forever to get a response, but a while back I wrote a > > question about Heterochromia on a genetics website. > > > > > > " Question: > > I have Heterochromia iridis (different colored eyes, where one eye > > is of two colors), and I was wondering if there are statistics on > > how many other people have this trait? My particular case is > > independent of disease or disorder, but I was curious. > > > > Answer: > > We were unable to find a specific number for the frequency of > > heterochromia of the iris in the general population. Asymmetry in > > the pigmentation of the irides probably occurs as an isolated > > phenomenon inherited as a dominant trait. This means a parent with > > heterochromia of the iris has a 50/50 chance to pass the trait to > > their offspring. " > > > > http://server2k.genetics.emory.edu/ask/user/view_response.pl? > > resp=142 & temp=3 Quote Link to comment Share on other sites More sharing options...
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