Guest guest Posted January 13, 2010 Report Share Posted January 13, 2010 Hi Diane, I cannot take credit for Mercola's language/quote from his article. It sounds like you know a lot about this...more than me. Mercola described zonulin as a protein if I recall. I do have a hunch that somewhere along the line, vaccine ingredients have played a role in creating the auto-immune environment which predisposes one to celiac. I can't prove it yet though Dr. Carley has her research www.drcarley.com that proves vaccines cause " all auto-immune " diseases through the over stimulation of the immune system. The short story is no vaccines and no gluten. I am doing well with the first one but not as good as my wife on the second. Little by little... Thank you for the info. " Leaky Gut " Intestinal Protein Linked to Autoimmune Disorders " Researchers report that a protein called zonulin appears to be responsible for maintaining the protective barrier in the small intestine, and that high levels of this protein are associated with disruptions in the barrier that allow foreign substances into the body's tissues. " http://articles.mercola.com/sites/articles/archive/2000/05/14/leaky-gut.aspx On Jan 12, 2010, at 5:43 PM, Evie wrote: > Hi, , > > Great job explaining this! Yes, thyroid problems abound among > people with celiac disease (caused by gluten intolerance). I was > hypothyroid and it actually normalized as a result of going gf and > soy-free! It is interesting, tho, that ALL auto-immune diseases > abound among celiacs, not just thyroid problems. It is because > gluten causes the body to excrete a hormone (I believe it is called > zonulin) which temporarily opens the tight junctions in the gut > (this is how the gut permeability gets started). Glutens also open > tjs in, at least, some of the organs--it is known they affect the > blood brain barrier, the lungs, the liver, and highly suspected, > that they open the tjs of the heart. Even normal people have this > reaction to eating glutens, but among people with gluten > intolerances, tjs open for a much longer time period and sometimes > the tjs refuse to close altogether. > > I didn't know if you knew this about other auto-immune diseases > being connected to eating glutens, but you really did a great job > describing how glutens do damage. They act the same way thru-out > the body. I have auto-immune TMJ, for instance. My jaw surgeons > went in to repair my left jaw joint and found there was nothing > there but dead tissue--it could not be repaired. They said it > looked like the remains of a building that had been " fire-bombed " -- > it was all gray and full of debris. This was due to my body > attacking glutens in or near my jaw joint. This is also how it is I > have so many diagnoses. I have auto-immune diseases upon auto- > immune diseases. > > Just thought you might be interested, if you do not already know this. > Take care, . My best to you and your wife, > Diane > > > >> >>> Just want to clarify one point for those who like to >> quibble and >>> argue, the autoimmune thyroid has been known as >> Hashimoto's Disease. >>> The orginal contributions claimed about this newer >> author is to >>> break that down into a more detailed understanding. >>> >>> >>> >>> ------------------------------------ >>> >>> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 26, 2010 Report Share Posted January 26, 2010 Hi, , You write: > Mercola described zonulin as a protein if I recall. > I do have a hunch that somewhere along the line, vaccine > ingredients > have played a role in creating the auto-immune environment > which > predisposes one to celiac. My reply: You are correct re zonulin being a protein--I mis-wrote when I called it a hormone. I know a bit about zonulin and zot ( " zonulin occult toxin " , which is what causes the brain damage in some people with celiac disease), as I have followed medical research studies concerning them since Dr Fasano first made the zonulin and zot/gluten connection in 2000, (which was also when I was dxed with CD). I think there's more here than meets the eye, too (regarding your thoughts on vaccines)--but I think the vacine issue is possibly related to the tight junction permeability gene dysfunction. I notice that I do not do well on vaccines. I come down with whatever I am being immunized for, even tho doctors claim these are not live viruses. But, like I mentioned yesterday, if one's blood-brain barrier is leaky, we are not getting the same amount of vaccine as a normal person would be getting; we are getting more. At least more to our brains; it would be interesting to know how this, then, would then affect the immune system. My best to you and your wife, Diane > >> > >>> Just want to clarify one point for those who > like to > >> quibble and > >>> argue, the autoimmune thyroid has been known > as > >> Hashimoto's Disease. > >>> The orginal contributions claimed about this > newer > >> author is to > >>> break that down into a more detailed > understanding. > >>> > >>> > >>> > >>> ------------------------------------ > >>> > >>> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 8, 2010 Report Share Posted February 8, 2010 Hi, , So sorry I am just getting to this email (and I missed sending the info for your presentation entirely)! How did that go for you, btw? Hope it went very well. You write: > I am surprised that anyone on this > list is still allowing needles to > penetrate your skin with animal DNA, antifreeze, MSG, > mercury, > aluminum, many viral components, etc., etc. in them. So true. It has been well over 20 years since I have had vaccines, flu shots, etc. I got very ill everytime I got one--it didn't make any sense to continue such a practice. lol Even my husband got ill with them. When my doctor insisted one year that they had now changed vaccines and they were no longer live virus, I tried one last time, mainly to appease him. The result was still the same--I came down with a serious flu-like illness. You write: > Do you know of any enzymes that can be taken regarding > zonulin or > anything in that area to help with celiac? Dr. Alesio Fasano was in drug trials last year for a pill called larazotide acetate. It went thru all 3 trial phases and was said to be on track to go to market in April of this year. That pill worked for minor gluten contaminations in celiacs who did not have bad on-going gut damage, as I understand. But what Dr. Fasano had hoped it would do is keep the tight junctions closed after one eats glutens and repair the damaged tjs which remained inoperational after particularly ill celiacs have gone gf. It did not do this, however, and so he did not, in the end, deem the trials a success. I have not heard whether he is going to continue onto marketing that pill for mild gluten ingestion. Another researcher, however, is now working on an enzyme pill (larazotide was a peptide). This enzyme pill is in trials now. (Actually my understanding is that there are several researchers in different countries competing at this at the moment.) They are saying the results so far are good for the one that is in trials, but this was leaked about the larazotide pill too--means nothing yet. Dr. Fasano is still looking for a tj fix, however, which is why my money is on him. The enzyme pill will not likely address the tjs. I personally do not see an enzyme as working, long run; it is similar to using devices to control ES. You are not actually curing ES with a device, but stunting the effects of emfs. Same would be true of an enzyme, I would think. Yes, if you can get an enzyme that is effective enough at digesting gluten it will help symptoms, but the tjs are still open; zonulin is still produced. (But certainly one would think researchers would know this too--so I may be wrong.) But I have noted that Dr Fasano has not moved on--his focus has not been changed by the enzyme race. There is also an enzyme pill already on the market in Canada being touted for use for celiacs. I forget the name of that product, but it *does not* work for celiacs. It may work for those with mild gluten intolerance. It has been around for at least 5 years and every year or so someone comes on the celiac forum pushing it. But those who have tried it got gut damage eventually; some right away. Best wishes to you and your wife, , Diane Quote Link to comment Share on other sites More sharing options...
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