Question

[Guest guest]

Alan I do know Prilosec does not do for me what Nexium will. Ruth

[Guest guest]

Nexium IS Prilosec, except that one side chain of the molecule is

altered. The company had to make a slight change when the patent ran

out on Prilosec so they could continue selling a patented drug. You

might remember (or you could do a Google search) that Nexium was

released right before Prilosec became available generically as

omeprazole. They had a massive ad campaign and it seemed to work.

Gwen

>

> I was under the impression that Nexium and Prilosec are not exactly

the same drug. I believe AstraZeneca replaced Prilosec (omeprazole)

with Nexium (esomeprazole) as their premier reflux/gerd medication of

choice, which in turn eventually lead to Prilosec being an OTC

medication. Not sure what the exact difference is, but I recall the

marketing being something along the lines of Prilosec as a

prevetative for acid reflux/GERD, while Nexium not only did the same

as Prilosec, it also repaired any damage done previously.

>

> Talk about life imitating life - as this message thread appeared on

this group, I opened some mail from Cigna asking if I wanted to

switch my Nexium to generic Prilosec. I'm pretty sure it's a money-

saving effort on their part. I'm still not convinced they're exactly

the same medication.

>

> Alan (of LI, NY)

> 316 | 293.5 |248.5 |190

> Start | Band | Now |Goal

> PreOp |10/5/07 |

> Diet

> Re: question

>

>

> > Nexium is called Prilosec over the counter.

> >

> >

> >

> > Judy

>

>

>

[Guest guest]

Exactly!! That is what I remember - the ad campaign. So the side chain of the

molecule (which I assume is the difference between the two generic names) really

makes no difference? If that's true, then " Grrrrrr " to AstraZeneca!!

Alan (of LI, NY)

316 | 293.5 |248.5 |190

Start | Band | Now |Goal

PreOp |10/5/07 |

Diet

Re: question

> Nexium IS Prilosec, except that one side chain of the molecule

> is

> altered. The company had to make a slight change when the

> patent ran

> out on Prilosec so they could continue selling a patented drug.

> You

> might remember (or you could do a Google search) that Nexium was

> released right before Prilosec became available generically as

> omeprazole. They had a massive ad campaign and it seemed to work.

> Gwen

[Guest guest]

Judy, If we're eating the good band diet we need, we should not need

a stool softener. It's always best to get the fiber we need from

whole grains, veggies, and fruits.

Also, be sure to get the minimum 80-100 oz a day of fluids - that is

essential to prevent constipation.

Not sure why your doc RX'd nexium - so you must ask HIM if and when

to discontinue it. Only your doc can advise about meds, as only he

knows your medical history and other essential things.

You have a very complicated medical situation, and we can only offer

general info here.

Sandy R

>

> Hi guys,

> I've got a question. When I was banded my Lapband doc gave me a

script for

> Colace which is a stool softener. Should I continue to take it? How

about

> Nexium?

>

> Judy

>

>

>

>

>

> **************************************See AOL's top rated recipes

> (http://food.aol.com/top-rated-recipes?NCID=aoltop00030000000004)

>

>

>

[Guest guest]

Yep, that side chain carbon (I think it was) is the only difference,

and makes NO clinical difference in the effectiveness of the drugs.

A very sneaky little " fix " for AstraZeneca to get around the loss of

their patent. And the docs seemed to eat it up with a big spoon--how

many people are prescribed Nexium now? Loads, partly because of all

the free samples the company made available, plus whatever other

perks they give the prescribing practitioners.

Which drug is given truly makes no difference clinically, and if you

want to test that out just get admitted to any mid-to-large size

hospital and have your doc prescribe Nexium in your admission

orders. The mid to large size hospitals will almost always

substitute omeprazole, without even consulting your doc because the

pharmacy has an agreement with all physicians with admitting

privileges that this substitution will occur, to save the hospital

money without comprimising the intended effect for the patient.

They do this with a couple other drugs too, like Zantac and its

cousins, and Xopenex, a nebulized medication for asthma and other

respiratory problems which is as different from albuterol as Nexium

is from Prilosec. The drug companies will have you believe that

their current patented version is newer and improved, but ask a

pharmacist for the truth. (No, I'm not a pharmacist.

Gwen

>

> Exactly!! That is what I remember - the ad campaign. So the side

chain of the molecule (which I assume is the difference between the

two generic names) really makes no difference? If that's true,

then " Grrrrrr " to AstraZeneca!!

>

> Alan (of LI, NY)

> 316 | 293.5 |248.5 |190

> Start | Band | Now |Goal

> PreOp |10/5/07 |

> Diet

> Re: question

>

>

> > Nexium IS Prilosec, except that one side chain of the molecule

> > is

> > altered. The company had to make a slight change when the

> > patent ran

> > out on Prilosec so they could continue selling a patented drug.

> > You

> > might remember (or you could do a Google search) that Nexium was

> > released right before Prilosec became available generically as

> > omeprazole. They had a massive ad campaign and it seemed to work.

> > Gwen

>

>

>

[Guest guest]

Thank you Gwen. Very informative. Not really surprising...although it was

news to me. I guess I'm not too old to learn something new .

Can't complain too much about the Nexium free samples though ... my doctor

loves me and gives out samples of my meds by the boat-load to me. I

remember when I switched from Prilosec to Nexium. I probably received about

6 months worth of samples, which at my normal $40/month for it, saved me

$240. Sigh... sadly, back when I saved that money, I was probably spending

the savings on food. But at least I wasn't getting acid reflux from the

food!!

Alan (of LI, NY)

316 |293.5 |248.5 |190

High |Band |Now |Goal

9/21/07 |10/5/07 |

From:

[mailto: ] On Behalf Of Gwen

Sent: Friday, December 28, 2007 12:34 PM

Subject: Re: question

Yep, that side chain carbon (I think it was) is the only difference,

and makes NO clinical difference in the effectiveness of the drugs.

A very sneaky little " fix " for AstraZeneca to get around the loss of

their patent. And the docs seemed to eat it up with a big spoon--how

many people are prescribed Nexium now? Loads, partly because of all

the free samples the company made available, plus whatever other

perks they give the prescribing practitioners.

Which drug is given truly makes no difference clinically, and if you

want to test that out just get admitted to any mid-to-large size

hospital and have your doc prescribe Nexium in your admission

orders. The mid to large size hospitals will almost always

substitute omeprazole, without even consulting your doc because the

pharmacy has an agreement with all physicians with admitting

privileges that this substitution will occur, to save the hospital

money without comprimising the intended effect for the patient.

They do this with a couple other drugs too, like Zantac and its

cousins, and Xopenex, a nebulized medication for asthma and other

respiratory problems which is as different from albuterol as Nexium

is from Prilosec. The drug companies will have you believe that

their current patented version is newer and improved, but ask a

pharmacist for the truth. (No, I'm not a pharmacist.

Gwen

[Guest guest]

For me, that is a symptom of a cold sore. Sometimes it's a blister,

but usually just a " crack. " Frequently I get a cold within the next

week. Try " Blixtex, " " Carmex, " or one of the other cold sore remedies.

in Atlanta

06/03/04

290/118

>

> In the last week or so I have had a crack appear in the corner of my

> mouth that is extremely painful and quite frankly, ugly. I think I

> remember a post that said this was caused by a deficiency in

> something or other, but for the life of me, I cannot remember what was

> said. If anyone knows, can you please repost?

>

> Thanks!

>

> Dr. R

> 8/16/06

> 335/191/???

>

[Guest guest]

For me, it means that I have not been eating my yogurt or getting my

acidophilus. If I take both every day, I won't get them at all. My whole family

is on the same " remedy " . Works for anyone with fever blisters too.

Re: Question

For me, that is a symptom of a cold sore. Sometimes it's a blister,

but usually just a " crack. " Frequently I get a cold within the next

week. Try " Blixtex, " " Carmex, " or one of the other cold sore remedies.

in Atlanta

06/03/04

290/118

>

> In the last week or so I have had a crack appear in the corner of my

> mouth that is extremely painful and quite frankly, ugly. I think I

> remember a post that said this was caused by a deficiency in

> something or other, but for the life of me, I cannot remember what was

> said. If anyone knows, can you please repost?

>

> Thanks!

>

> Dr. R

> 8/16/06

> 335/191/???

>

________________________________________________________________________

More new features than ever. Check out the new AOL Mail ! -

http://webmail.aol.com

[Guest guest]

Thanks -

> >

> > In the last week or so I have had a crack appear in the corner of my

> > mouth that is extremely painful and quite frankly, ugly. I think I

> > remember a post that said this was caused by a deficiency in

> > something or other, but for the life of me, I cannot remember what was

> > said. If anyone knows, can you please repost?

> >

> > Thanks!

> >

> > Dr. R

> > 8/16/06

> > 335/191/???

> >

>

[Guest guest]

I believe, with myself it is a vitamin B deficiency. I only get a

crack...not a 'cold sore' type appearance at all. I also know that

it is worse in winter for me...perhaps it is because of the dryer air,

due to heating.

> >

> > In the last week or so I have had a crack appear in the corner of my

> > mouth that is extremely painful and quite frankly, ugly. I think I

> > remember a post that said this was caused by a deficiency in

> > something or other, but for the life of me, I cannot remember what was

> > said. If anyone knows, can you please repost?

> >

> > Thanks!

> >

> > Dr. R

> > 8/16/06

> > 335/191/???

> >

>

[Guest guest]

Thanks, I haven't been eating my yogurt daily like I should. This is

a great reminder to not let things slide.

> >

> > In the last week or so I have had a crack appear in the corner of my

> > mouth that is extremely painful and quite frankly, ugly. I think I

> > remember a post that said this was caused by a deficiency in

> > something or other, but for the life of me, I cannot remember what was

> > said. If anyone knows, can you please repost?

> >

> > Thanks!

> >

> > Dr. R

> > 8/16/06

> > 335/191/???

> >

>

>

>

>

>

> ________________________________________________________________________

> More new features than ever. Check out the new AOL Mail ! -

http://webmail.aol.com

>

>

>

[Guest guest]

That is exactly what I have, a crack that keeps cracking further

whenever I open my mouth to speak or eat. I will up my vitamin B -

Thanks for the suggestion.

> > >

> > > In the last week or so I have had a crack appear in the corner of my

> > > mouth that is extremely painful and quite frankly, ugly. I think I

> > > remember a post that said this was caused by a deficiency in

> > > something or other, but for the life of me, I cannot remember

what was

> > > said. If anyone knows, can you please repost?

> > >

> > > Thanks!

> > >

> > > Dr. R

> > > 8/16/06

> > > 335/191/???

> > >

> >

>

[Guest guest]

The one thing that helped my mouth get better was after I had an iron infusion-

so make sure you are not anemic.

@...: skymtn@...: Thu, 3 Jan 2008

15:44:26 +0000Subject: Re: Question

That is exactly what I have, a crack that keeps cracking furtherwhenever I open

my mouth to speak or eat. I will up my vitamin B -Thanks for the suggestion.---

In , " Terry " <tberkis@...> wrote:>> I believe, with

myself it is a vitamin B deficiency. I only get a> crack...not a 'cold sore'

type appearance at all. I also know that> it is worse in winter for me...perhaps

it is because of the dryer air,> due to heating.> > > > > >> > > In the last week or so I have had a crack appear in the corner

of my> > > mouth that is extremely painful and quite frankly, ugly. I think I> >

> remember a post that said this was caused by a deficiency in> > > something or

other, but for the life of me, I cannot rememberwhat was> > > said. If anyone

knows, can you please repost?> > > > > > Thanks!> > > > > > Dr. R > > >

8/16/06> > > 335/191/???> > >> >>

_________________________________________________________________

Share life as it happens with the new Windows Live.

http://www.windowslive.com/share.html?ocid=TXT_TAGHM_Wave2_sharelife_012008

[Guest guest]

The one thing that helped my mouth get better was after I had an iron infusion-

so make sure you are not anemic.

@...: skymtn@...: Thu, 3 Jan 2008

15:44:26 +0000Subject: Re: Question

That is exactly what I have, a crack that keeps cracking furtherwhenever I open

my mouth to speak or eat. I will up my vitamin B -Thanks for the suggestion.---

In , " Terry " <tberkis@...> wrote:>> I believe, with

myself it is a vitamin B deficiency. I only get a> crack...not a 'cold sore'

type appearance at all. I also know that> it is worse in winter for me...perhaps

it is because of the dryer air,> due to heating.> > > > > >> > > In the last week or so I have had a crack appear in the corner

of my> > > mouth that is extremely painful and quite frankly, ugly. I think I> >

> remember a post that said this was caused by a deficiency in> > > something or

other, but for the life of me, I cannot rememberwhat was> > > said. If anyone

knows, can you please repost?> > > > > > Thanks!> > > > > > Dr. R > > >

8/16/06> > > 335/191/???> > >> >>

_________________________________________________________________

Make distant family not so distant with Windows Vista® + Windows Live™.

http://www.microsoft.com/windows/digitallife/keepintouch.mspx?ocid=TXT_TAGLM_CPC\

_VideoChat_distantfamily_012008

[Guest guest]

i think i've beern away too long.

george

> >

> > Exactly!! That is what I remember - the ad campaign. So the side

> chain of the molecule (which I assume is the difference between the

> two generic names) really makes no difference? If that's true,

> then " Grrrrrr " to AstraZeneca!!

> >

> > Alan (of LI, NY)

> > 316 | 293.5 |248.5 |190

> > Start | Band | Now |Goal

> > PreOp |10/5/07 |

> > Diet

> > Re: question

> >

> >

> > > Nexium IS Prilosec, except that one side chain of the molecule

> > > is

> > > altered. The company had to make a slight change when the

> > > patent ran

> > > out on Prilosec so they could continue selling a patented drug.

> > > You

> > > might remember (or you could do a Google search) that Nexium

was

> > > released right before Prilosec became available generically as

> > > omeprazole. They had a massive ad campaign and it seemed to

work.

> > > Gwen

> >

> >

> >

[Guest guest]

My major response to rituxan/steroid treatment and cytoxan/rituxan/prednisone

was soreness of involved nodes. This included unexplained internal pain.

One of my first signs of recurring disease is generally sore nodes also.,

Bonnie

Don't tell God how big the storm is-

Tell the storm how BIG God is!

[Guest guest]

>

> Can achalasia effect the heart?

>

When I was an ICU Nurse years ago I took care of a man who had

Achalasia but he also had diverticulum in his esophagus, pockets that

form for no real reason in your esophagus. These pockets can hold

food for days at a time or can create passages between the organs in

the chest.

Unlike diverticulum that forms in the GI tract, these can connect

with the lungs or the heart. This gentleman had his esophagus

connect to his decending Aorta the big blood vessel that supplies

blood to the whole body. He began to vomit large amounts of bright

red blood. He went to his local hospital where a smart surgeon

quickly did an incision after a local and pain meds were given and he

put a Dacron Patch over the hole and stapled it in place and packed

the esophagus with an old fashion balloon device that was used to

stop Esophageal Varices from bleeding and gauze.

Despite out best efforts the gentleman ended up with brain damage

from the loss of blood and a stroke, but he is alive and is aware of

what is going on he has no connection from his esophagus just a

pocket that has a drain attached to it.

I hope this does not scare anyone again, as this is rare, very rare

Joe

[Guest guest]

Thank you for your response Joe- I too have had diveticulitis in my

esophagus nd had it removed twice, last time was five years ago, i

have ha d a lot of chest painand until lately assumed it was because

of my achalasia but other symptoms caused concern with my doctor and

so he sent me to a cardiologist. I have had two days of testing and

the results will come in on the twenty first so we will see then.

again thanks

> >

> > Can achalasia effect the heart?

> >

> When I was an ICU Nurse years ago I took care of a man who had

> Achalasia but he also had diverticulum in his esophagus, pockets

that

> form for no real reason in your esophagus. These pockets can hold

> food for days at a time or can create passages between the organs

in

> the chest.

>

> Unlike diverticulum that forms in the GI tract, these can connect

> with the lungs or the heart. This gentleman had his esophagus

> connect to his decending Aorta the big blood vessel that supplies

> blood to the whole body. He began to vomit large amounts of bright

> red blood. He went to his local hospital where a smart surgeon

> quickly did an incision after a local and pain meds were given and

he

> put a Dacron Patch over the hole and stapled it in place and packed

> the esophagus with an old fashion balloon device that was used to

> stop Esophageal Varices from bleeding and gauze.

>

> Despite out best efforts the gentleman ended up with brain

damage

> from the loss of blood and a stroke, but he is alive and is aware

of

> what is going on he has no connection from his esophagus just a

> pocket that has a drain attached to it.

>

> I hope this does not scare anyone again, as this is rare, very

rare

>

> Joe

>

[Guest guest]

jmr12667 wrote:

> ... Unlike diverticulum that forms in the GI tract, these can connect

> with the lungs or the heart. ...

I saw a case study similar to that. In this case the esophagus became so

large that although it didn't grow together it would push against the

heart causing it to beat funny.

There have been studies done looking at groups of patients with

achalasia to see if they have more heart problems than normal groups. In

general these studies don't seem to find much of a connection if any.

Most of us have idiopathic achalasia which means we don't know what

caused it. It may be possible that there are some uncommon causes that

do have a connection while in general achalasia does not have a

connection to heart problems.

Speaking of causes of achalasia and heart problems, I saw report

yesterday about interstitial cells of cajal (ICC) in patients with

achalasia. In looking at tissue samples from their esophagi it was found

that patients with achalasia fell into two groups, those with two many

interstitial cells of cajal and those with too few. This may reflect two

different causes, or not, who knows. Maybe this will in time help us to

know. There is a lot of research into these cells being done and they

are known to play a not yet fully understood part in GI motility and

heart rhythm. Like the nerves that are damaged in achalasia the ICC are

also nitric oxide active and can be damaged by NO produced by the immune

system, such as in inflammation. (Sound familiar?)

Alterations in the Density of Interstitial Cells of Cajal in Achalasia

http://www.springerlink.com/content/5134k7rn0737712v/

Inactivation of inducible nitric oxide synthase protects intestinal

pacemaker cells from postoperative damage

http://www.blackwell-synergy.com/doi/abs/10.1113/jphysiol.2006.126482

notan

[Guest guest]

I'll updaet all of you on what my cardiologist says:)

Ms Dee

> > ... Unlike diverticulum that forms in the GI tract, these can

connect

> > with the lungs or the heart. ...

>

> I saw a case study similar to that. In this case the esophagus

became so

> large that although it didn't grow together it would push against

the

> heart causing it to beat funny.

>

> There have been studies done looking at groups of patients with

> achalasia to see if they have more heart problems than normal

groups. In

> general these studies don't seem to find much of a connection if

any.

> Most of us have idiopathic achalasia which means we don't know what

> caused it. It may be possible that there are some uncommon causes

that

> do have a connection while in general achalasia does not have a

> connection to heart problems.

>

> Speaking of causes of achalasia and heart problems, I saw report

> yesterday about interstitial cells of cajal (ICC) in patients with

> achalasia. In looking at tissue samples from their esophagi it was

found

> that patients with achalasia fell into two groups, those with two

many

> interstitial cells of cajal and those with too few. This may

reflect two

> different causes, or not, who knows. Maybe this will in time help

us to

> know. There is a lot of research into these cells being done and

they

> are known to play a not yet fully understood part in GI motility

and

> heart rhythm. Like the nerves that are damaged in achalasia the ICC

are

> also nitric oxide active and can be damaged by NO produced by the

immune

> system, such as in inflammation. (Sound familiar?)

>

> Alterations in the Density of Interstitial Cells of Cajal in

Achalasia

> http://www.springerlink.com/content/5134k7rn0737712v/

>

> Inactivation of inducible nitric oxide synthase protects intestinal

> pacemaker cells from postoperative damage

> http://www.blackwell-

synergy.com/doi/abs/10.1113/jphysiol.2006.126482

>

> notan

>

[Guest guest]

My heart problems. mainly atrial fibrillation did develop after my esophagectomy but my Drs. believe the problems I have are genetic in origin as both of my parents had heart related problems. However since my surgery I have noticed that if I exercise immediately after eating I get a shortness of breath since my stomach is in my chest I have always believed that the fullness of the esoph/stomach puts pressure on the lungs. I don't have any scientific facts to back this up but if I wait an hour or so after eating I don't have the shortness of breath. I am curious as to whether anyone else has experienced this after surgery?

F

From: achalasia [mailto:achalasia ] On Behalf Of notan ostrichSent: Thursday, January 17, 2008 10:54 AMachalasia Subject: Re: Re: Question

jmr12667 wrote:> ... Unlike diverticulum that forms in the GI tract, these can connect > with the lungs or the heart. ...I saw a case study similar to that. In this case the esophagus became so large that although it didn't grow together it would push against the heart causing it to beat funny.There have been studies done looking at groups of patients with achalasia to see if they have more heart problems than normal groups. In general these studies don't seem to find much of a connection if any. Most of us have idiopathic achalasia which means we don't know what caused it. It may be possible that there are some uncommon causes that do have a connection while in general achalasia does not have a connection to heart problems.Speaking of causes of achalasia and heart problems, I saw report yesterday about interstitial cells of cajal (ICC) in patients with achalasia. In looking at tissue samples from their esophagi it was found that patients with achalasia fell into two groups, those with two many interstitial cells of cajal and those with too few. This may reflect two different causes, or not, who knows. Maybe this will in time help us to know. There is a lot of research into these cells being done and they are known to play a not yet fully understood part in GI motility and heart rhythm. Like the nerves that are damaged in achalasia the ICC are also nitric oxide active and can be damaged by NO produced by the immune system, such as in inflammation. (Sound familiar?)Alterations in the Density of Interstitial Cells of Cajal in Achalasiahttp://www.springerlink.com/content/5134k7rn0737712v/Inactivation of inducible nitric oxide synthase protects intestinal pacemaker cells from postoperative damagehttp://www.blackwell-synergy.com/doi/abs/10.1113/jphysiol.2006.126482notan

[Guest guest]

I havent had an esophagectomy yet I have had two Heller Myotomies

Re: Re: Question

jmr12667 wrote:> ... Unlike diverticulum that forms in the GI tract, these can connect > with the lungs or the heart. ...I saw a case study similar to that. In this case the esophagus became so large that although it didn't grow together it would push against the heart causing it to beat funny.There have been studies done looking at groups of patients with achalasia to see if they have more heart problems than normal groups. In general these studies don't seem to find much of a connection if any. Most of us have idiopathic achalasia which means we don't know what caused it. It may be possible that there are some uncommon causes that do have a connection while in general achalasia does not have a connection to heart problems.Speaking of causes of achalasia and heart problems, I saw report yesterday about interstitial cells of cajal (ICC) in patients with achalasia. In looking

at tissue samples from their esophagi it was found that patients with achalasia fell into two groups, those with two many interstitial cells of cajal and those with too few. This may reflect two different causes, or not, who knows. Maybe this will in time help us to know. There is a lot of research into these cells being done and they are known to play a not yet fully understood part in GI motility and heart rhythm. Like the nerves that are damaged in achalasia the ICC are also nitric oxide active and can be damaged by NO produced by the immune system, such as in inflammation. (Sound familiar?)Alterations in the Density of Interstitial Cells of Cajal in Achalasiahttp://www.springer link.com/ content/5134k7rn 0737712v/Inactivation of inducible nitric oxide synthase protects intestinal pacemaker cells from

postoperative damagehttp://www.blackwel l-synergy. com/doi/abs/ 10.1113/jphysiol .2006.126482notan

Be a better friend, newshound, and know-it-all with Mobile. Try it now.

[Guest guest]

,

I had my 'ectomy in March of 2007 - can't believe I'm almost at one

year. WOW.

Anyway, I have not had any such issues or heart related problems.

in NY

Re: Re: Question

>

>

> jmr12667 wrote:

> > ... Unlike diverticulum that forms in the GI tract, these can

> connect

> > with the lungs or the heart. ...

>

> I saw a case study similar to that. In this case the esophagus

> became so

> large that although it didn't grow together it would push against

> the

> heart causing it to beat funny.

>

> There have been studies done looking at groups of patients with

> achalasia to see if they have more heart problems than normal

> groups. In

> general these studies don't seem to find much of a connection if

> any.

> Most of us have idiopathic achalasia which means we don't know

> what

> caused it. It may be possible that there are some uncommon causes

> that

> do have a connection while in general achalasia does not have a

> connection to heart problems.

>

> Speaking of causes of achalasia and heart problems, I saw report

> yesterday about interstitial cells of cajal (ICC) in patients with

> achalasia. In looking at tissue samples from their esophagi it was

> found

> that patients with achalasia fell into two groups, those with two

> many

> interstitial cells of cajal and those with too few. This may

> reflect two

> different causes, or not, who knows. Maybe this will in time help

> us to

> know. There is a lot of research into these cells being done and

> they

> are known to play a not yet fully understood part in GI motility

> and

> heart rhythm. Like the nerves that are damaged in achalasia the

> ICC are

> also nitric oxide active and can be damaged by NO produced by the

> immune

> system, such as in inflammation. (Sound familiar?)

>

> Alterations in the Density of Interstitial Cells of Cajal in

Achalasia

> http://www.springer link.com/ content/5134k7rn 0737712v/

>

> Inactivation of inducible nitric oxide synthase protects

> intestinal

> pacemaker cells from postoperative damage

> http://www.blackwel l-synergy. com/doi/abs/ 10.1113/jphysiol

> .2006.126482

> notan

>

>

>

>

>

>

>

_______________________________________________________________________

_____________Never miss a thing. Make your home page.

> http://www./r/hs

[Guest guest]

I have atrial fibrillation since 1998, at which time I also was diagnosed with Acid Reflux, Spasmatic E. In 2007 was diagnosed with A and had surgery in Dec. 2007. But it makes me wonder if the two are connected. But I also have a long family history of heart problems but never atrial fibrillation mostly heartattacks. Millie in Virginia <efitzgar@...> wrote: My heart problems. mainly atrial fibrillation did develop after my esophagectomy but my Drs. believe the problems I have are genetic in origin as both of my parents had heart related problems. However since my surgery I have noticed that if I exercise immediately after eating I get a shortness of breath since my stomach is in my chest I have always believed that the fullness of the esoph/stomach puts pressure on the lungs. I don't have any scientific facts to back this up but if I wait an hour or so after eating I don't have the shortness of breath. I am curious as to whether anyone else has experienced this after surgery? F From: achalasia [mailto:achalasia ] On Behalf Of notan ostrichSent: Thursday, January 17, 2008 10:54 AMachalasia Subject: Re: Re: Question jmr12667 wrote:> ... Unlike diverticulum that forms in the GI tract, these can connect > with the lungs or the heart. ...I saw a case study similar to that. In this case the esophagus became so large that although it didn't grow together it would push against the heart causing it to beat funny.There have been studies done looking at groups of patients with achalasia to see if they have more heart problems than normal groups. In general these studies

don't seem to find much of a connection if any. Most of us have idiopathic achalasia which means we don't know what caused it. It may be possible that there are some uncommon causes that do have a connection while in general achalasia does not have a connection to heart problems.Speaking of causes of achalasia and heart problems, I saw report yesterday about interstitial cells of cajal (ICC) in patients with achalasia. In looking at tissue samples from their esophagi it was found that patients with achalasia fell into two groups, those with two many interstitial cells of cajal and those with too few. This may reflect two different causes, or not, who knows. Maybe this will in time help us to know. There is a lot of research into these cells being done and they are known to play a not yet fully understood part in GI motility and heart rhythm. Like the nerves that are damaged in achalasia the ICC are also nitric

oxide active and can be damaged by NO produced by the immune system, such as in inflammation. (Sound familiar?)Alterations in the Density of Interstitial Cells of Cajal in Achalasiahttp://www.springerlink.com/content/5134k7rn0737712v/Inactivation of inducible nitric oxide synthase protects intestinal pacemaker cells from postoperative damagehttp://www.blackwell-synergy.com/doi/abs/10.1113/jphysiol.2006.126482notan

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[Guest guest]

Hi,

I also had my surgery that date. I was the same way.I just got my first fill

so I hope that changes!!

boobarb41 <qutegirl003@...> wrote:

I had my lapband procedure on Dec 6,07. I have not had a fill yet. I

seem to be able to eat a lot more than what I should and I am hungry 2

hours after I eat. Is this something normal that everyone goes thru?

---------------------------------

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